메뉴 건너뛰기




Volumn , Issue , 2008, Pages 169-185

The Genomics and Regulation of the Human Septin Genes

Author keywords

Alternate splicing; Disease; Gene family; Gene regulation; Neoplasia; Septin; Transcript; Translational control; UTR

Indexed keywords


EID: 82755198278     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470779705.ch7     Document Type: Chapter
Times cited : (4)

References (41)
  • 1
    • 31544452500 scopus 로고    scopus 로고
    • MSF-A interacts with hypoxia-inducible factor-lalpha and augments hypoxia-inducible factor transcriptional activation to affect tumorigenicity and angiogenesis
    • Amir, S., Wang, R., Matzkin, H. et al. (2006) MSF-A interacts with hypoxia-inducible factor-lalpha and augments hypoxia-inducible factor transcriptional activation to affect tumorigenicity and angiogenesis. Cancer Research, 66, 856-66.
    • (2006) Cancer Research , vol.66 , pp. 856-866
    • Amir, S.1    Wang, R.2    Matzkin, H.3
  • 2
    • 0034898703 scopus 로고    scopus 로고
    • An ins(X;ll)(q24;q23) fuses the MLL and the Septin 6/KIAA0128 gene in an infant with AML-M2
    • Borkhardt, A., Teigler-Schlegel, A., Fuchs, U. et al. (2001) An ins(X;ll)(q24;q23) fuses the MLL and the Septin 6/KIAA0128 gene in an infant with AML-M2. Genes, Chromosomes and Cancer, 32, 82-88.
    • (2001) Genes, Chromosomes and Cancer , vol.32 , pp. 82-88
    • Borkhardt, A.1    Teigler-Schlegel, A.2    Fuchs, U.3
  • 3
    • 10744222073 scopus 로고    scopus 로고
    • Altered expression of the septin gene, SEPT9, in ovarian neoplasia
    • Burrows, J.F., Chanduloy, S., Mcllhatton, M.A. et al. (2003) Altered expression of the septin gene, SEPT9, in ovarian neoplasia. The Journal of Pathology, 201, 581-88.
    • (2003) The Journal of Pathology , vol.201 , pp. 581-588
    • Burrows, J.F.1    Chanduloy, S.2    Mcllhatton, M.A.3
  • 4
    • 33745232735 scopus 로고    scopus 로고
    • Inherited focal, episodic neuropathies: hereditary neuropathy with liability to pressure palsies and hereditary neuralgic amyotrophy
    • Chance, P.F. (2006) Inherited focal, episodic neuropathies: hereditary neuropathy with liability to pressure palsies and hereditary neuralgic amyotrophy. Neuromolecular Medicine, 8, 159-74.
    • (2006) Neuromolecular Medicine , vol.8 , pp. 159-174
    • Chance, P.F.1
  • 5
    • 33745728414 scopus 로고    scopus 로고
    • A systematic analysis of disease-associated variants in the 3' regulatory regions of human protein-coding genes I: general principles and overview
    • Chen, J.M., Ferec, C. and Cooper, D.N. (2006) A systematic analysis of disease-associated variants in the 3' regulatory regions of human protein-coding genes I: general principles and overview. Human Genetics, 120, 1-21.
    • (2006) Human Genetics , vol.120 , pp. 1-21
    • Chen, J.M.1    Ferec, C.2    Cooper, D.N.3
  • 6
    • 34347400412 scopus 로고    scopus 로고
    • A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of human alternative splicing variants
    • De la Grange, P., Dutertre, M., Correa, M. and Auboeuf, D. (2007) A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of human alternative splicing variants. BMC Bioinformatics, 8, 180-94.
    • (2007) BMC Bioinformatics , vol.8 , pp. 180-194
    • De La Grange, P.1    Dutertre, M.2    Correa, M.3    Auboeuf, D.4
  • 7
    • 12344290346 scopus 로고    scopus 로고
    • Mechanisms of translational control by the 3' UTR in development and differentiation
    • De Moor, C.H., Meijer, H. and Lissenden, S. (2005) Mechanisms of translational control by the 3' UTR in development and differentiation. Seminars in Cell and Developmental Biology, 16, 49-58.
    • (2005) Seminars in Cell and Developmental Biology , vol.16 , pp. 49-58
    • De Moor, C.H.1    Meijer, H.2    Lissenden, S.3
  • 8
    • 0141889928 scopus 로고    scopus 로고
    • Molecular analysis of t(X;11)(q24;q23) in an infant with AML-M4
    • Fu, J.F., Liang, D.C., Yang, C.P. et al. (2003) Molecular analysis of t(X;11)(q24;q23) in an infant with AML-M4. Genes, Chromosomes and Cancer, 38, 253-59.
    • (2003) Genes, Chromosomes and Cancer , vol.38 , pp. 253-259
    • Fu, J.F.1    Liang, D.C.2    Yang, C.P.3
  • 10
    • 33344471142 scopus 로고    scopus 로고
    • Regulation of gene expression by alternative untranslated regions
    • Hughes, T.A. (2006) Regulation of gene expression by alternative untranslated regions. Trends in Genetics, 22, 119-22.
    • (2006) Trends in Genetics , vol.22 , pp. 119-122
    • Hughes, T.A.1
  • 11
    • 0034008329 scopus 로고    scopus 로고
    • Genomic and expression analyses of alternatively spliced transcripts of the MLL septin-like fusion gene (MSF) that map to a 17q25 region of loss in breast and ovarian tumors
    • Kalikin, L.M., Sims, H.L. and Petty, E.M. (2000) Genomic and expression analyses of alternatively spliced transcripts of the MLL septin-like fusion gene (MSF) that map to a 17q25 region of loss in breast and ovarian tumors. Genomics, 63, 165-72.
    • (2000) Genomics , vol.63 , pp. 165-172
    • Kalikin, L.M.1    Sims, H.L.2    Petty, E.M.3
  • 12
    • 0041520660 scopus 로고    scopus 로고
    • MLL/SEPTIN6 chimeric transcript from inv ins(X;11)(q24;q23q13) in acute monocytic leukemia: report of a case and review of the literature
    • Kim, H.J., Ki, C.S., Park, Q. et al. (2003) MLL/SEPTIN6 chimeric transcript from inv ins(X;11)(q24;q23q13) in acute monocytic leukemia: report of a case and review of the literature. Genes, Chromosomes and Cancer, 38, 8-12.
    • (2003) Genes, Chromosomes and Cancer , vol.38 , pp. 8-12
    • Kim, H.J.1    Ki, C.S.2    Park, Q.3
  • 13
    • 0022552131 scopus 로고
    • Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
    • Kozak, M. (1986) Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell, 44, 283-92.
    • (1986) Cell , vol.44 , pp. 283-292
    • Kozak, M.1
  • 14
    • 0025792297 scopus 로고
    • Structural features in eukaryotic mRNAs that modulate the initiation of translation
    • Kozak, M. (1991) Structural features in eukaryotic mRNAs that modulate the initiation of translation. The Journal of Biological Chemistry, 266, 19867-70.
    • (1991) The Journal of Biological Chemistry , vol.266 , pp. 19867-19870
    • Kozak, M.1
  • 15
    • 34548289288 scopus 로고    scopus 로고
    • Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7
    • Kremer, B.E., Adang, L.A. and Macara, I.G. (2007) Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. Cell, 130, 837-50.
    • (2007) Cell , vol.130 , pp. 837-850
    • Kremer, B.E.1    Adang, L.A.2    Macara, I.G.3
  • 16
    • 27144483990 scopus 로고    scopus 로고
    • Mutations in SEPT9 cause hereditary neuralgic amyotrophy
    • Kuhlenbaumer, G., Hannibal, M.C., Nelis, E. et al. (2005) Mutations in SEPT9 cause hereditary neuralgic amyotrophy. Nature Genetics, 37, 1044-46.
    • (2005) Nature Genetics , vol.37 , pp. 1044-1046
    • Kuhlenbaumer, G.1    Hannibal, M.C.2    Nelis, E.3
  • 17
    • 0033671655 scopus 로고    scopus 로고
    • A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif
    • Larisch, S., Yi, Y., Lotan, R. et al. (2000) A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif. Nature Cell Biology, 12, 915-21.
    • (2000) Nature Cell Biology , vol.12 , pp. 915-921
    • Larisch, S.1    Yi, Y.2    Lotan, R.3
  • 18
    • 19344366251 scopus 로고    scopus 로고
    • Mechanistic links between nonsense mediated mRNA decay and pre-mRNA splicing in mammalian cells
    • Lejeune, F. and Maquat, L.E. (2005) Mechanistic links between nonsense mediated mRNA decay and pre-mRNA splicing in mammalian cells. Current Opinion in Cell Biology, 17, 309-15.
    • (2005) Current Opinion in Cell Biology , vol.17 , pp. 309-315
    • Lejeune, F.1    Maquat, L.E.2
  • 20
    • 39749180354 scopus 로고    scopus 로고
    • DNA-methylation biomarkers for blood-based colorectal cancer screening
    • Lofton-Day, C., Model, F., DeVos, T. et al. (2007) DNA-methylation biomarkers for blood-based colorectal cancer screening. Clinical Chemistry, 54, 414-23.
    • (2007) Clinical Chemistry , vol.54 , pp. 414-423
    • Lofton-Day, C.1    Model, F.2    DeVos, T.3
  • 21
    • 34447341733 scopus 로고    scopus 로고
    • Translational control of SEPT9 isoforms is perturbed in disease
    • McDade, S.S., Hall, P.A. and Russell, S.E. (2007) Translational control of SEPT9 isoforms is perturbed in disease. Human Molecular Genetics, 16, 742-52.
    • (2007) Human Molecular Genetics , vol.16 , pp. 742-752
    • McDade, S.S.1    Hall, P.A.2    Russell, S.E.3
  • 22
    • 0035855652 scopus 로고    scopus 로고
    • Genomic organization, complex splicing pattern and expression of a human septin gene on chromosome 17q25.3
    • Mcllhatton, M.A., Burrows, J.F., Donaghy, P.G. et al. (2001) Genomic organization, complex splicing pattern and expression of a human septin gene on chromosome 17q25.3. Oncogene, 20, 5930-39.
    • (2001) Oncogene , vol.20 , pp. 5930-5939
    • Mcllhatton, M.A.1    Burrows, J.F.2    Donaghy, P.G.3
  • 23
    • 0031440018 scopus 로고    scopus 로고
    • A human gene similar to Drosophila melanogaster peanut maps to the DiGeorge syndrome region of 22q11
    • McKie, J.M., Sutherland, H.F., Harvey, E. et al. (1997) A human gene similar to Drosophila melanogaster peanut maps to the DiGeorge syndrome region of 22q11. Human Genetics, 101, 6-12.
    • (1997) Human Genetics , vol.101 , pp. 6-12
    • McKie, J.M.1    Sutherland, H.F.2    Harvey, E.3
  • 26
    • 0030057177 scopus 로고    scopus 로고
    • Isolation and mapping of a human gene (DIFF6) homologous to yeast CDC3, CDC10, CDC11, and CDC12, and mouse Diff6
    • Mori, T., Miura, K., Fujiwara, T. et al. (1996) Isolation and mapping of a human gene (DIFF6) homologous to yeast CDC3, CDC10, CDC11, and CDC12, and mouse Diff6. Cytogenetics and Cell Genetics, 73, 224-27.
    • (1996) Cytogenetics and Cell Genetics , vol.73 , pp. 224-227
    • Mori, T.1    Miura, K.2    Fujiwara, T.3
  • 27
    • 0025245455 scopus 로고
    • Lymphocyte HEV adhesion variants differ in the expression of multiple gene sequences
    • Nottenburg, C., Gallatin, W.M. and St John, T. (1990) Lymphocyte HEV adhesion variants differ in the expression of multiple gene sequences. Gene, 95, 279-84.
    • (1990) Gene , vol.95 , pp. 279-284
    • Nottenburg, C.1    Gallatin, W.M.2    John, T.3
  • 28
    • 0037081079 scopus 로고    scopus 로고
    • SEPTIN6, a human homologue to mouse Septin6, is fused to MLL in infant acute myeloid leukemia with complex chromosomal abnormalities involving 11q23 and Xq24
    • Ono, R., Taki, T., Taketani, T. et al. (2002) SEPTIN6, a human homologue to mouse Septin6, is fused to MLL in infant acute myeloid leukemia with complex chromosomal abnormalities involving 11q23 and Xq24. Cancer Research, 62, 333-37.
    • (2002) Cancer Research , vol.62 , pp. 333-337
    • Ono, R.1    Taki, T.2    Taketani, T.3
  • 30
    • 0032961592 scopus 로고    scopus 로고
    • Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene
    • Paavola, P., Horelli-Kuitunen, N., Palotie, A. and Peltonen, L. (1999) Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene. Genomics, 55, 122-25.
    • (1999) Genomics , vol.55 , pp. 122-125
    • Paavola, P.1    Horelli-Kuitunen, N.2    Palotie, A.3    Peltonen, L.4
  • 31
    • 0036132908 scopus 로고    scopus 로고
    • The septin CDCrel-1 is dispensable for normal development and neurotransmitter release
    • Peng, X.R., Jia, Z., Zhang, Y. et al. (2002) The septin CDCrel-1 is dispensable for normal development and neurotransmitter release. Molecular and Cellular Biology, 1, 378-87.
    • (2002) Molecular and Cellular Biology , vol.1 , pp. 378-387
    • Peng, X.R.1    Jia, Z.2    Zhang, Y.3
  • 32
    • 0034282804 scopus 로고    scopus 로고
    • Isolation and mapping of a human septin gene to a region on chromosome 17q, commonly deleted in sporadic epithelial ovarian tumors
    • Russell, S.E., McIlhatton, M.A., Burrows, J.F. et al. (2000) Isolation and mapping of a human septin gene to a region on chromosome 17q, commonly deleted in sporadic epithelial ovarian tumors. Cancer Research, 60, 4729-34.
    • (2000) Cancer Research , vol.60 , pp. 4729-4734
    • Russell, S.E.1    McIlhatton, M.A.2    Burrows, J.F.3
  • 33
    • 0025321246 scopus 로고
    • Splice junctions, branch point sites, and exons: sequence statistics, identification, and applications to genome project
    • Senapathy, P., Shapiro, M.B. and Harris, N.L. (1990) Splice junctions, branch point sites, and exons: sequence statistics, identification, and applications to genome project. Methods in Enzymology, 183, 252-78.
    • (1990) Methods in Enzymology , vol.183 , pp. 252-278
    • Senapathy, P.1    Shapiro, M.B.2    Harris, N.L.3
  • 34
    • 0037063170 scopus 로고    scopus 로고
    • MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site
    • Slater, D.J., Hilgenfeld, E., Rappaport, E.F. et al. (2002) MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site. Oncogene, 21, 4706-14.
    • (2002) Oncogene , vol.21 , pp. 4706-4714
    • Slater, D.J.1    Hilgenfeld, E.2    Rappaport, E.F.3
  • 35
    • 0037414429 scopus 로고    scopus 로고
    • Cloning and functional characterization of human septin 10, a novel member of septin family cloned from dendritic cells
    • Sui, L., Zhang, W., Liu, Q. et al. (2003) Cloning and functional characterization of human septin 10, a novel member of septin family cloned from dendritic cells. Biochemical and Biophysical Research Communications, 304, 93-98.
    • (2003) Biochemical and Biophysical Research Communications , vol.304 , pp. 93-98
    • Sui, L.1    Zhang, W.2    Liu, Q.3
  • 36
    • 34948892039 scopus 로고    scopus 로고
    • SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/ SEPT11 and resistance to Rho/Rhotekin-signaling
    • Sudo, K., Ito, H., Iwamoto, I. et al. (2007) SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/ SEPT11 and resistance to Rho/Rhotekin-signaling. Hum Mutat., 28, 1005-13.
    • (2007) Hum Mutat , vol.28 , pp. 1005-1013
    • Sudo, K.1    Ito, H.2    Iwamoto, I.3
  • 37
    • 0034801664 scopus 로고    scopus 로고
    • Characterization of tissue-and cell-type-specific expression of a novel human septin family gene, Bradeion
    • Tanaka, M., Tanaka, T., Kijima, H. et al. (2001) Characterization of tissue-and cell-type-specific expression of a novel human septin family gene, Bradeion. Biochemical and Biophysical Research Communications, 286, 547-53.
    • (2001) Biochemical and Biophysical Research Communications , vol.286 , pp. 547-553
    • Tanaka, M.1    Tanaka, T.2    Kijima, H.3
  • 38
    • 0032496621 scopus 로고    scopus 로고
    • Structure and expression of the human septin gene HCDCREL-1
    • Yagi, M., Zieger, B., Roth, G.J. and Ware, J. (1998) Structure and expression of the human septin gene HCDCREL-1. Gene, 212, 229-36.
    • (1998) Gene , vol.212 , pp. 229-236
    • Yagi, M.1    Zieger, B.2    Roth, G.J.3    Ware, J.4
  • 39
    • 0034615922 scopus 로고    scopus 로고
    • Phosphorylation of a new brain-specific septin, G-septin, by cGMP-dependent protein kinase
    • Xue, J., Wang, X., Malladi, C.S. et al. (2000) Phosphorylation of a new brain-specific septin, G-septin, by cGMP-dependent protein kinase. The Journal of Biological Chemistry, 275, 10047-56.
    • (2000) The Journal of Biological Chemistry , vol.275 , pp. 10047-10056
    • Xue, J.1    Wang, X.2    Malladi, C.S.3
  • 40
    • 0030854265 scopus 로고    scopus 로고
    • Alternative expression of platelet glycoprotein Ib(beta) mRNA from an adjacent 5' gene with an imperfect polyadenylation signal sequence
    • Zieger, B., Hashimoto, Y. and Ware, J. (1997) Alternative expression of platelet glycoprotein Ib(beta) mRNA from an adjacent 5' gene with an imperfect polyadenylation signal sequence. The Journal of Clinical Investigation, 99, 520-25.
    • (1997) The Journal of Clinical Investigation , vol.99 , pp. 520-525
    • Zieger, B.1    Hashimoto, Y.2    Ware, J.3
  • 41
    • 0034739803 scopus 로고    scopus 로고
    • Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2
    • Zieger, B., Tran, H., Hainmann, I. et al. (2000) Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2. Gene, 261, 197-203.
    • (2000) Gene , vol.261 , pp. 197-203
    • Zieger, B.1    Tran, H.2    Hainmann, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.