Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 48, 2011, Pages 19365-19370

  Hastie, Kathryn M ^a   Liu, Tong ^b   Li, Sheng ^b   King, Liam B ^a   Ngo, Nhi ^a   Zandonatti, Michelle A ^a   Woods Jr , Virgil L ^b   De La Torre, Juan Carlos ^a   Saphire, Erica Ollmann ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Structural biology; Virology

Indexed keywords

RIBONUCLEOPROTEIN; SINGLE STRANDED RNA; VIRUS NUCLEOPROTEIN;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DEUTERIUM HYDROGEN EXCHANGE; HYDROGEN BOND; LASSA VIRUS; MASS SPECTROMETRY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RNA BINDING; RNA REPLICATION; RNA TRANSCRIPTION; SITE DIRECTED MUTAGENESIS; VIRUS GENOME; VIRUS MORPHOLOGY;

CELL LINE; CRYSTALLIZATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LASSA VIRUS; MODELS, MOLECULAR; PROTEIN CONFORMATION; RIBONUCLEOPROTEINS; RNA, VIRAL; VIRAL PROTEINS;

EID: 82755167958     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1108515108     Document Type: Article

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