Alterations of ATM and CADM1 in chromosomal 11q22.3-23.2 region are associated with the development of invasive cervical carcinoma

Human Genetics

Volumn 130, Issue 6, 2011, Pages 735-748

  Mazumder Indra, Dipanjana ^a   Mitra, Sraboni ^a   Roy, Anup ^b   Mondal, Ranajit Kumar ^a   Basu, Partha Sarathi ^a   Roychoudhury, Susanta ^c   Chakravarty, Runu ^d   Panda, Chinmay Kumar ^a  

^a CHITTARANJAN NATIONAL CANCER INSTITUTE   (India)

^b MIDNAPORE MEDICAL COLLEGE AND HOSPITAL   (India)

^c INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^d INDIAN COUNCIL OF MEDICAL RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 1; MESSENGER RNA; PROTEIN; PROTEIN CADM1; PROTEIN PPP2R1B; PROTEIN SDHD; UNCLASSIFIED DRUG;

ARTICLE; CANCER GROWTH; CANCER INVASION; CANCER STAGING; CARCINOGENESIS; CHROMOSOME 11Q; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA DAMAGE; EARLY CANCER; FEMALE; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; METHYLATION; MUTATION RATE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SURVIVAL; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU;

CELL ADHESION MOLECULES; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CERVICAL INTRAEPITHELIAL NEOPLASIA; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 11; DISEASE PROGRESSION; DNA DAMAGE; DNA METHYLATION; DNA-BINDING PROTEINS; EPIGENOMICS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HUMANS; IMMUNOGLOBULINS; MUTATION; NEOPLASM STAGING; PAPILLOMAVIRUS INFECTIONS; PROMOTER REGIONS, GENETIC; PROTEIN KINASES; PROTEIN PHOSPHATASE 2; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS; UTERINE CERVICAL NEOPLASMS;

EID: 82555174410     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-011-1015-8     Document Type: Article

References (64)

1. L Ai QN Vo C Zuo L Li W Ling JY Suen E Hanna KD Brown CY Fan 2004 Ataxia-telangiectasia-mutated (ATM) gene in head and neck squamous cell carcinoma: promoter hypermethylation with clinical correlation in 100 cases Cancer Epidemiol Biomarkers Prev 13 150 156 14744748 10.1158/1055-9965.EPI-082-3 1:CAS:528:DC%2BD2cXmsVWiuw%3D%3D (Pubitemid 38116634)
2. BE Baysal RE Ferrell JE Willett-Brozick EC Lawrence D Myssiorek A Bosch A van der Mey PE Taschner WS Rubinstein EN Myers CW Richard 3rd CJ Cornelisse P Devilee B Devlin 2000 Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma Science 287 848 851 10657297 10.1126/science.287.5454. 848 1:CAS:528:DC%2BD3cXhtVehtrs%3D (Pubitemid 30084326)
3. G Carpenter 2003 Nuclear localization and possible functions of receptor tyrosine kinases Curr Opin Cell Biol 15 143 148 12648669 10.1016/S0955-0674(03) 00015-2 1:CAS:528:DC%2BD3sXitV2ms78%3D (Pubitemid 36332188)
4. S Chakrabarti S Dasgupta S Roy A Bhar A Sengupta A Roy K Ray NP Bhattacharyya B Roy CK Panda S Roychoudhury 2001 Microsatellite instability in squamous cell carcinoma of head and neck from the Indian patient population Int J Cancer 92 555 561 11304691 10.1002/ijc.1233 1:CAS:528:DC%2BD3MXjs1eit7k%3D (Pubitemid 32319430)
5. HC Chou CH Chen HS Lee CZ Lee GT Huang PM Yang PH Lee JC Sheu 2007 Alterations of tumour suppressor gene PPP2R1B in hepatocellular carcinoma Cancer Lett 253 138 143 17324501 10.1016/j.canlet.2007.01.016 1:CAS:528: DC%2BD2sXmtlWhsLo%3D (Pubitemid 46874734)
6. N Chunder S Mandal A Roy S Roychoudhury CK Panda 2004 Analysis of different deleted regions in chromosome 11 and their interrelations in early- and late-onset breast tumors: association with cyclin D1 amplification and survival Diagn Mol Pathol 13 172 182 15322430 10.1097/01.pas.0000124337.49401.0b (Pubitemid 39121744)
7. M Davis A Hitchcock WD Foulkes IG Campbell 1996 Refinement of two chromosome 11q regions of loss of heterozygosity in ovarian cancer Cancer Res 56 741 744 8631007 1:CAS:528:DyaK28XhtVClsLw%3D (Pubitemid 26055461)
8. De Preter K, Vandesompele J, Hoebeeck J, Vandenbroecke C, Smet J, Nuyts A, Laureys G, Combaret V, Van Roy N, Roels F, Van Coster R, Praet M, De Paepe A, Speleman F (2004) No evidence for involvement of SDHD in neuroblastoma pathogenesis. BMC Cancer 4:55
9. T Fukami H Fukuhara M Kuramochi T Maruyama K Isogai M Sakamoto S Takamoto Y Murakami 2003 Promoter methylation of the TSLC1 gene in advanced lung tumors and various cancer cell lines Int J Cancer 107 53 59 12925956 10.1002/ijc.11348 1:CAS:528:DC%2BD3sXntlKmtrg%3D (Pubitemid 37100085)
10. M Gentile M Ahnstrom F Schon S Wingren 2001 Candidate tumour suppressor genes at 11q23-q24 in breast cancer: evidence of alterations in PIG8, a gene involved in p53-induced apoptosis Oncogene 20 7753 7760 11753653 10.1038/sj.onc.1204993 1:CAS:528:DC%2BD3MXptFOntL4%3D (Pubitemid 33121948)
11. S Ghosh A Ghosh GP Maiti N Alam A Roy B Roy S Roychoudhury CK Panda 2008 Alterations of 3p21.31 tumor suppressor genes in head and neck squamous cell carcinoma: correlation with progression and prognosis Int J Cancer 123 2594 2604 18792900 10.1002/ijc.23834 1:CAS:528:DC%2BD1cXhtlyru7jO
12. O Gimm M Armanios H Dziema HP Neumann C Eng 2000 Somatic and occult germ-line mutations in SDHD, a mitochondrial complex II gene, in nonfamilial pheochromocytoma Cancer Res 60 6822 6825 11156372 1:CAS:528: DC%2BD3MXjsVKrsQ%3D%3D (Pubitemid 32059145)
13. AA Goodarzi JC Jonnalagadda P Douglas D Young R Ye GB Moorhead SP Lees-Miller KK Khanna 2004 Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A EMBO J 23 4451 4461 15510216 10.1038/sj.emboj.7600455 1:CAS:528:DC%2BD2cXpsFahurg%3D (Pubitemid 39601970)
14. W Habano T Sugai S Nakamura N Uesugi T Higuchi M Terashima S Horiuchi 2003 Reduced expression and loss of heterozygosity of the SDHD gene in colorectal and gastric cancer Oncol Rep 10 1375 1380 12883710 1:CAS:528:DC%2BD3sXmvFWnsr8%3D
15. GM Hampton LA Penny RN Baergen A Larson C Brewer S Liao RM Busby-Earle AW Williams CM Steel CC Bird, et al. 1994 Loss of heterozygosity in cervical carcinoma: subchromosomal localization of a putative tumor-suppressor gene to chromosome 11q22-q24 Proc Natl Acad Sci USA 91 6953 6957 8041728 10.1073/pnas.91.15.6953 1:CAS:528:DyaK2cXlt1Kltbs%3D (Pubitemid 24226780)
16. S Hemmer VM Wasenius C Haglund Y Zhu S Knuutila K Franssila H Joensuu 2002 Alterations in the suppressor gene PPP2R1B in parathyroid hyperplasias and adenomas Cancer Genet Cytogenet 134 13 17 11996789 10.1016/S0165-4608(01)00597-0 1:CAS:528:DC%2BD38XjsVWjsrs%3D (Pubitemid 34462102)
17. JG Herman JR Graff S Myohanen BD Nelkin SB Baylin 1996 Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands Proc Natl Acad Sci USA 93 9821 9826 8790415 10.1073/pnas.93.18.9821 1:CAS:528:DyaK28XlsFeht7Y%3D (Pubitemid 26296693)
18. H Hirawake M Taniwaki A Tamura S Kojima K Kita 1997 Cytochrome b in human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the components in liver mitochondria and chromosome assignment of the genes for the large (SDHC) and small (SDHD) subunits to 1q21 and 11q23 Cytogenet Cell Genet 79 132 138 9533030 10.1159/000134700 1:CAS:528:DyaK1cXislKgtb8%3D (Pubitemid 28107834)
19. H Hirawake M Taniwaki A Tamura H Amino E Tomitsuka K Kita 1999 Characterization of the human SDHD gene encoding the small subunit of cytochrome b (cybS) in mitochondrial succinate-ubiquinone oxidoreductase Biochim Biophys Acta 1412 295 300 10482792 10.1016/S0005-2728(99)00071-7 1:CAS:528: DyaK1MXltV2hsb8%3D (Pubitemid 29356110)
20. KT Huang A Dobrovic SB Fox 2009 No evidence for promoter region methylation of the succinate dehydrogenase and fumarate hydratase tumour suppressor genes in breast cancer BMC Res Notes 2 194 19778456 10.1186/1756-0500-2-194
21. AB Hui KW Lo SY Chan J Kwong AS Chan DP Huang 2002 Absence of SDHD mutations in primary nasopharyngeal carcinomas Int J Cancer 97 875 877 11857371 10.1002/ijc.10066 1:CAS:528:DC%2BD38XhtVShsLo%3D (Pubitemid 34106348)
22. KK Khanna 2000 Cancer risk and the ATM gene: a continuing debate J Natl Cancer Inst 92 795 802 10814674 10.1093/jnci/92.10.795 1:CAS:528: DC%2BD3cXktVKitb8%3D (Pubitemid 30368035)
23. WJ Kim QN Vo M Shrivastav TA Lataxes KD Brown 2002 Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line Oncogene 21 3864 3871 12032824 10.1038/sj.onc.1205485 1:CAS:528:DC%2BD38Xks12gu7c%3D (Pubitemid 34620854)
24. M Koi H Morita H Yamada H Satoh JC Barrett M Oshimura 1989 Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa Mol Carcinog 2 12 21 2730761 10.1002/mc.2940020103 1:CAS:528:DyaL1MXktlOhtrg%3D (Pubitemid 19148370)
25. SV Kozlov ME Graham C Peng P Chen PJ Robinson MF Lavin 2006 Involvement of novel autophosphorylation sites in ATM activation EMBO J 25 3504 3514 16858402 10.1038/sj.emboj.7601231 1:CAS:528:DC%2BD28XnvVGls70%3D (Pubitemid 44264861)
26. K Laake A Odegard TI Andersen IK Bukholm R Karesen JM Nesland L Ottestad Y Shiloh AL Borresen-Dale 1997 Loss of heterozygosity at 11q23.1 in breast carcinomas: indication for involvement of a gene distal and close to ATM Genes Chromosomes Cancer 18 175 180 9071570 10.1002/(SICI)1098-2264(199703)18: 3<175::AID-GCC4>3.0.CO;2-Z 1:CAS:528:DyaK2sXitlars7w%3D (Pubitemid 27120336)
27. PA Lazo 1999 The molecular genetics of cervical carcinoma Br J Cancer 80 2008 2018 10471054 10.1038/sj.bjc.6690635 1:CAS:528:DyaK1MXlvVais7o%3D (Pubitemid 29391289)
28. AS Lee YC Seo A Chang S Tohari KW Eu F Seow-Choen JO McGee 2000 Detailed deletion mapping at chromosome 11q23 in colorectal carcinoma Br J Cancer 83 750 755 10952779 10.1054/bjoc.2000.1366 1:CAS:528:DC%2BD3cXntFOhs7g%3D
29. J Li Z Zhang M Bidder MC Funk L Nguyen PJ Goodfellow JS Rader 2005 IGSF4 promoter methylation and expression silencing in human cervical cancer Gynecol Oncol 96 150 158 15589594 10.1016/j.ygyno.2004.08.050 1:CAS:528: DC%2BD2cXhtVKltL3N (Pubitemid 39612430)
30. W Li W Jian X Xiaoping L Yingfeng X Tao X Xiaoyan 2006 Enhanced radiation-mediated cell killing of human cervical cancer cells by small interference RNA silencing of ataxia telangiectasia-mutated protein Int J Gynecol Cancer 16 1620 1630 16884376 10.1111/j.1525-1438.2006.00636.x 1:STN:280:DC%2BD28vmvFSkuw%3D%3D (Pubitemid 44060390)
31. SY Lin K Makino W Xia A Matin Y Wen KY Kwong L Bourguignon MC Hung 2001 Nuclear localization of EGF receptor and its potential new role as a transcription factor Nat Cell Biol 3 802 808 11533659 10.1038/ncb0901-802 1:CAS:528:DC%2BD3MXmvF2ls74%3D (Pubitemid 32842685)
32. KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 402 408 11846609 10.1006/meth.2001.1262 1:CAS:528:DC%2BD38XhtFelt7s%3D (Pubitemid 34164012)
33. VI Loginov AV Maliukova A Seregin Iu DS Khodyrev TP Kazubskaia VD Ermilova RF Gar'kavtseva LL Kiselev ER Zabarovskii EA Braga 2004 Methylation of the promoter region of the RASSF1A gene, a candidate tumor suppressor, in primary epithelial tumors Mol Biol 38 654 667 10.1023/B:MBIL.0000037007.71787.b9 1:STN:280:DC%2BD2cvoslyhsg%3D%3D (Pubitemid 39177841)
34. M Masuda M Yageta H Fukuhara M Kuramochi T Maruyama A Nomoto Y Murakami 2002 The tumor suppressor protein TSLC1 is involved in cell-cell adhesion J Biol Chem 277 31014 31019 12050160 10.1074/jbc.M203620200 1:CAS:528: DC%2BD38XmsF2jsro%3D (Pubitemid 34970805)
35. Mazumder Indra D, Mitra S, Singh RK, Dutta S, Roy A, Mondal RK, Basu PS, Roychoudhury S, Panda CK (2010) Inactivation of CHEK1 and EI24 are associated with the development of invasive cervical carcinoma: clinical and prognostic implications. Int J Cancer. doi: 10.1002/ijc.25849
36. BC Misra ES Srivatsan 1989 Localization of HeLa cell tumor-suppressor gene to the long arm of chromosome II Am J Hum Genet 45 565 577 2577469 1:STN:280:DyaK3Mzjs1alsw%3D%3D (Pubitemid 19261444)
37. S Mitra D Mazumder Indra N Bhattacharya RK Singh PS Basu RK Mondal A Roy ER Zabarovsky S Roychoudhury CK Panda 2010 RBSP3 is frequently altered in premalignant cervical lesions: clinical and prognostic significance Genes Chromosomes Cancer 49 155 170 19885927 1:CAS:528:DC%2BD1MXhsFGjsrjF
38. CA Moody LA Laimins 2009 Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation PLoS Pathog 5 e1000605 19798429 10.1371/journal.ppat.1000605
39. CA Moody LA Laimins 2010 Human papillomavirus oncoproteins: pathways to transformation Nat Rev Cancer 10 550 560 20592731 10.1038/nrc2886 1:CAS:528:DC%2BC3cXotFeltLo%3D
40. Y Murakami 2005 Involvement of a cell adhesion molecule, TSLC1/IGSF4, in human oncogenesis Cancer Sci 96 543 552 16128739 10.1111/j.1349-7006.2005.00089. x 1:CAS:528:DC%2BD2MXhtVyhtLvF (Pubitemid 41488417)
41. M Negrini D Rasio GM Hampton S Sabbioni S Rattan SL Carter AL Rosenberg GF Schwartz Y Shiloh WK Cavenee, et al. 1995 Definition and refinement of chromosome 11 regions of loss of heterozygosity in breast cancer: identification of a new region at 11q23.3 Cancer Res 55 3003 3007 7606718 1:CAS:528: DyaK2MXmvVyitrw%3D
42. RM Overmeer FE Henken PJ Snijders D Claassen-Kramer J Berkhof TJ Helmerhorst DA Heideman SM Wilting Y Murakami A Ito CJ Meijer RD Steenbergen 2008 Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC J Pathol 215 388 397 18498117 10.1002/path.2367 1:CAS:528:DC%2BD1cXhtVKns77K
43. F Perrone S Suardi E Pastore P Casieri M Orsenigo S Caramuta G Dagrada M Losa L Licitra P Bossi S Staurengo M Oggionni L Locati G Cantu M Squadrelli A Carbone MA Pierotti S Pilotti 2006 Molecular and cytogenetic subgroups of oropharyngeal squamous cell carcinoma Clin Cancer Res 12 6643 6651 17121883 10.1158/1078-0432.CCR-06-1759 1:CAS:528:DC%2BD28Xht1elsL%2FN (Pubitemid 44876832)
44. P Pisani F Bray DM Parkin 2002 Estimates of the world-wide prevalence of cancer for 25 sites in the adult population Int J Cancer 97 72 81 11774246 10.1002/ijc.1571 1:CAS:528:DC%2BD3MXovFKrurk%3D (Pubitemid 33104397)
45. TJ Pugh M Keyes L Barclay A Delaney M Krzywinski D Thomas K Novik C Yang A Agranovich M McKenzie WJ Morris PL Olive MA Marra RA Moore 2009 Sequence variant discovery in DNA repair genes from radiosensitive and radiotolerant prostate brachytherapy patients Clin Cancer Res 15 5008 5016 19638463 10.1158/1078-0432.CCR-08-3357 1:CAS:528:DC%2BD1MXptl2gtrk%3D
46. HA Pulido MJ Fakruddin A Chatterjee ED Esplin N Beleno G Martinez H Posso GA Evans VV Murty 2000 Identification of a 6-cM minimal deletion at 11q23.1-23.2 and exclusion of PPP2R1B gene as a deletion target in cervical cancer Cancer Res 60 6677 6682 11118052 1:CAS:528:DC%2BD3cXosl2itro%3D
47. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor, New York
48. MH Schiffman LA Brinton 1995 The epidemiology of cervical carcinogenesis Cancer 76 1888 1901 8634980 10.1002/1097-0142(19951115)76:10+<1888::AID- CNCR2820761305>3.0.CO;2-H 1:STN:280:DyaK283ivF2mtA%3D%3D
49. T Shingai W Ikeda S Kakunaga K Morimoto K Takekuni S Itoh K Satoh M Takeuchi T Imai M Monden Y Takai 2003 Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells J Biol Chem 278 35421 35427 12826663 10.1074/jbc.M305387200 1:CAS:528:DC%2BD3sXntVWqu7Y%3D (Pubitemid 37102311)
50. RK Singh S Dasgupta N Bhattacharya N Chunder R Mondal A Roy S Mandal S Roychowdhury CK Panda 2005 Deletion in chromosome 11 and Bcl-1/Cyclin D1 alterations are independently associated with the development of uterine cervical carcinoma J Cancer Res Clin Oncol 131 395 406 15856299 10.1007/s00432-004-0655-7 1:CAS:528:DC%2BD2MXjs1OlsLc%3D (Pubitemid 40674625)
51. RD Steenbergen D Kramer BJ Braakhuis PL Stern RH Verheijen CJ Meijer PJ Snijders 2004 TSLC1 gene silencing in cervical cancer cell lines and cervical neoplasia J Natl Cancer Inst 96 294 305 14970278 10.1093/jnci/djh031 1:CAS:528:DC%2BD2cXhsV2qtLc%3D (Pubitemid 38256274)
52. M Takagi D Delia L Chessa S Iwata T Shigeta Y Kanke K Goi M Asada M Eguchi C Kodama S Mizutani 1998 Defective control of apoptosis, radiosensitivity, and spindle checkpoint in ataxia telangiectasia Cancer Res 58 4923 4929 9810001 1:CAS:528:DyaK1cXnt1yisL0%3D (Pubitemid 28503692)
53. Y Takagi M Futamura K Yamaguchi S Aoki T Takahashi S Saji 2000 Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers Gut 47 268 271 10896920 10.1136/gut.47.2.268 1:CAS:528:DC%2BD3cXlvVygu7o%3D (Pubitemid 30489772)
54. YR Thorstenson A Roxas R Kroiss MA Jenkins KM Yu T Bachrich D Muhr TL Wayne G Chu RW Davis TM Wagner PJ Oefner 2003 Contributions of ATM mutations to familial breast and ovarian cancer Cancer Res 63 3325 3333 12810666 1:CAS:528:DC%2BD3sXks1ehsr0%3D (Pubitemid 36735890)
55. A Tripathi Bhar S Banerjee N Chunder A Roy A Sengupta B Roy S Roychowdhury CK Panda 2003 Differential alterations of the genes in the CDKN2A-CCND1-CDK4-RB1 pathway are associated with the development of head and neck squamous cell carcinoma in Indian patients J Cancer Res Clin Oncol 129 642 650 14586645 10.1007/s00432-003-0485-z (Pubitemid 37452630)
56. G Walter M Mumby 1993 Protein serine/threonine phosphatases and cell transformation Biochim Biophys Acta 1155 207 226 8395218 1:CAS:528:DyaK2cXlt12l (Pubitemid 23246696)
57. SS Wang ED Esplin JL Li L Huang A Gazdar J Minna GA Evans 1998 Alterations of the PPP2R1B gene in human lung and colon cancer Science 282 284 287 9765152 10.1126/science.282.5387.284 1:CAS:528:DyaK1cXmsF2jurc%3D (Pubitemid 28487198)
58. SS Wang A Virmani AF Gazdar JD Minna GA Evans 1999 Refined mapping of two regions of loss of heterozygosity on chromosome band 11q23 in lung cancer Genes Chromosomes Cancer 25 154 159 10337999 10.1002/(SICI)1098-2264(199906)25: 2<154::AID-GCC11>3.0.CO;2-W 1:CAS:528:DyaK1MXjsFartLs%3D (Pubitemid 29226598)
59. K Watabe A Ito YI Koma Y Kitamura 2003 IGSF4: a new intercellular adhesion molecule that is called by three names, TSLC1, SgIGSF and SynCAM, by virtue of its diverse function Histol Histopathol 18 1321 1329 12973698 1:CAS:528:DC%2BD3sXps1alsL0%3D (Pubitemid 37265032)
60. R Wu DC Connolly X Ren ER Fearon KR Cho 1999 Somatic mutations of the PPP2R1B candidate tumor suppressor gene at chromosome 11q23 are infrequent in ovarian carcinomas Neoplasia 1 311 314 10935485 10.1038/sj.neo.7900042 1:CAS:528:DC%2BD3cXksVyhtw%3D%3D
61. MHP Xia 2008 Great potential of MicroRNA in cancer stem cell J Cancer Mol 4 79 89 1:CAS:528:DC%2BD1cXhtFKgs7bI
62. P Zhang KS Bhakta PL Puri RO Newbury JR Feramisco JY Wang 2003 Association of ataxia telangiectasia mutated (ATM) gene mutation/deletion with rhabdomyosarcoma Cancer Biol Ther 2 87 91 12673126
63. Z Zhang DS Gerhard L Nguyen J Li A Traugott PC Huettner JS Rader 2005 Fine mapping and evaluation of candidate genes for cervical cancer on 11q23 Genes Chromosomes Cancer 43 95 103 15672406 10.1002/gcc.20151 1:CAS:528:DC%2BD2MXjt1Kqtr8%3D (Pubitemid 40490358)
64. H zur Hausen 2000 Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis J Natl Cancer Inst 92 690 698 10793105 10.1093/jnci/92.9.690 1:CAS:528:DC%2BD3cXjslSns7Y%3D (Pubitemid 30365529)