Deletion in chromosome 11 and Bcl-1/Cyclin D1 alterations are independently associated with the development of uterine cervical carcinoma

Journal of Cancer Research and Clinical Oncology

Volumn 131, Issue 6, 2005, Pages 395-406

  Singh, Ratnesh Kumar ^a   Dasgupta, Santanu ^b   Bhattacharya, Nilanjana ^a   Chunder, Neelanjana ^a   Mondal, Ranjit ^a   Roy, Anup ^c   Mandal, Syamsundar ^a   Roychowdhury, Susanta ^d   Panda, Chinmay Kumar ^a  

^a CHITTARANJAN NATIONAL CANCER INSTITUTE   (India)

^b UNIVERSITY OF CINCINNATI   (United States)

^c MEDICAL COLLEGE AND HOSPITAL   (India)

^d INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Bcl 1 Cyclin D1 alteration; Chromosome 11; HPV infection; LOH; Tumor suppressor gene (s); Uterine cervical carcinoma

Indexed keywords

BCL 1 PROTEIN; CYCLIN D1; PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CHROMOSOME 11; CHROMOSOME DELETION; CHROMOSOME DELETION 11; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GENE FREQUENCY; GENE LOCUS; HUMAN; HUMAN CELL; MICROSATELLITE MARKER; POLYMORPHIC LOCUS; PRIORITY JOURNAL; SOUTHERN BLOTTING; STATISTICAL SIGNIFICANCE; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; UTERINE CERVIX CARCINOMA;

ADENOCARCINOMA; ADULT; AGED; BLOTTING, SOUTHERN; CARCINOMA, SQUAMOUS CELL; CERVICAL INTRAEPITHELIAL NEOPLASIA; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 11; FEMALE; GENE AMPLIFICATION; GENES, BCL-1; HUMANS; MICROSATELLITE REPEATS; MIDDLE AGED; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; POLYMERASE CHAIN REACTION; PROGNOSIS; REPRESSOR PROTEINS; UTERINE CERVICAL NEOPLASMS;

EID: 18744415181     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-004-0655-7     Document Type: Article

References (52)

1. Akiyama N, Tsuruta H, Sasaki H, Sakamoto H, Hamaguchi M, Ohmura Y, Seto M, Ueda R, Hirai H, Yazaki Y, Sugimura T, Terada M (1994) Messenger RNA levels of five genes located at chromosome 11q13 in B cell tumors with chromosome translocation t(11;14) (q13;q32). Cancer Res 54:377-379
2. Arai Y, Hosoda F, Kobayashi H, Arai K, Hayashi Y, Kamada N, Kaneko Y, Ohki M (1997) The inv (11) (p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10. Blood 89:3936-3944
3. Azzena A, Zen T, Ferrara A, Brunetti V, Vasile C, Marchetti M (1994) Risk factors for breast cancer. Case-control study results. Eur J Gynecol Oncol 15:386-392
4. Balaram P, Nalinakumari KR, Abraham E, Balan A, Hareendran NK, Bernard HU, Chan SY (1995) Human papillomavirus in 91 oral cancers from Indian betel quid chewers - high prevalence and multiplicity of infections. Int J Cancer 61:450-454
5. Berenson JR, Yang J, Mickel RA (1989) Frequent amplification of the Bc1-1 locus in head and neck squamous cell carcinoma. Oncogene 4:1111-1116
6. Cattani P, Hohaus S, Bellacosa A, Genuardi M, Cavallo S, Rovella V, Almadori G, Cadoni G, Galli J, Maurizi M, Fadda G, Neri G (1998) Association between cyclin D1 (CCND1) gene amplification and human papillomavirus infection in human laryngeal squamous cell carcinoma. Clin Cancer Res 4:2585-2589
7. Cheung TH, Yu MMY, Lo KWK, Yim SF, Chung TKH, Wong YF (2001) Alteration of Cyclin D1 and CDK4 gene in carcinoma of uterine cervix. Cancer Lett 166:199-206
8. Chunder N, Mandal S, Roy A, Roychoudhury S, Panda CK (2004) Analysis of different deleted regions in chromosome 11 and their interrelations in early and late-onset breast tumors: association with Cyclin D1 amplification and survival. Diagn Mol Pathol 13:172-182
9. Dasgupta S, Mukherjee N, Roy S, Roy A, Roychowdhury S, Panda CK (2002) Mapping of the candidate tumor suppressor gene's loci on human chromosome 3 in head and neck squamous cell carcinoma of Indian patient population. Oral Oncol 38:6-15
10. Dasgupta S, Chakraborty SB, Roy A, Roychowdhury S, Panda CK (2003) Differential deletions of chromosome 3p are associated with the development of uterine cervical carcinoma in Indian patients. Mol Pathol 56:263-269
11. D' Costa J, Saranath D, Dedhia P, Sanghvi V, Mehta AR (1998) Detection of HPV-16 genome in human oral cancers and potentially malignant lesions from India. Oral Oncol 34:413-420
12. Donnellan R, Chetty R (1998) Cyclin D1 and human neoplasia. Mol Pathol 51:1-7
13. Gentile M, Ahnstrom M, Schon F, Wingren S (2001) Candidate tumor suppressor genes at 11q23-24 in breast cancer: evidence of alterations in PIG8, a gene involved in p53 -induced apoptosis. Oncogene 20:7753-7760
14. Hampton GM, Penny LA, Baergen RN, Larson A, Brewer C, Liao S, Busby-Earle RMC, Williams AWR, Steel CM, Bird CC, Stanbridge EJ, Evans GA (1994) Loss of heterozygosity in cervical carcinoma: subchromosomal localization of a putative tumor suppressor gene to chromosome 11q22-24. Proc Natl Acad Sci USA 9:6953-6957
15. Hampton GM, Larson AA, Baergen RN, Sommers RL, Kern S, Cavenee WK (1996) Simultaneous assessment of loss of heterozygosity at multiple microsatellite loci using semi- automated fluorescence based detection: subregional mapping of chromosome 4 in cervical carcinoma. Proc Natl Acad Sci USA 93:6704-6709
16. Hu RJ, Lee MP, Connors TD, Johnson LA, Burn TC, Su K, Landes GM, Feinberg AP (1997) A 2.5- Mb transcript map of a tumor suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes. Genomics 46:9-17
17. Jares P, Fernandez PL, Campo E, Nadal A, Bosch F, Aiza G (1994) PRAD-1/Cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryngeal carcinomas. Cancer Res 54:4813-4817
18. Jesudasan RA, Rahman RA, Chandrasherakharappa S, Evans GA, Srivatsan ES (1995) Deletion and translocation of chromosome 11q13 sequences in cervical carcinoma cell lines. Am J Hum Genet 56:705-715
19. Koi M, Morita H, Yamada H, Satoh H, Barrett JC, Oshimura M (1989) Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa. Mol Carcinog 2:12-21
20. Krissansen GW, Owen MJ, Verbi M, Crumpton MJ (1986) Primary structure of the T3 γ subunit of the T3/T cell antigen receptor complex deduced from cDNA sequences: evolution of the T3 γ and δ subunits. EMBO J 8:1799-1808
21. Kurzrock R, Ku S, Talpaz M (1995) Abnormalities in the PRAD1 (CYCLIN D1/BCL-1) Oncogene are frequent in cervical and vulvar squamous cell carcinoma cell lines. Cancer 75:584-590
22. Kyomoto R, Kumazawa H, Toda Y, Sakaida N, Okamura A, Iwanaga M, Shintaku M, Yamashita T, Hiai H, Fukumoto M (1997) Cyclin -D1-Gene amplification is a more potent prognostic factor than its protein overexpression in human head and neck squamous cell carcinoma. Int J Cancer 74:576-581
23. Lazo PA (1999) The molecular genetics of cervical carcinoma. Br J Cancer 80:2008-2018
24. Martin ES, Rossano C, Pentimalli F, Yoder K, Fishel R, Himelstein AL, Martin SE, Godwin AK, Negrin M, Croce CM (2003) The BCSC-1 locus at chromosome 11q23-24 is a candidate tumor suppressor gene. Proc Natl Acad Sci USA 100:11517-11522
25. Milde-Langosch K, Riethdorf S (2003) Role of cell cycle regulatory protein in gynecological cancer. J Cell Physiol 196:224-244
26. Mitra AB, Murthy VVVS, Pratap M, Sodhani P, Chaganti R (1994) ERBB2 (HER2/neu) Oncogene is frequently amplified in squamous cell carcinoma of the uterine cervix. Cancer Res 54:637-639
27. Mondal G, Tripathi A, Bhattacharya N, Sikadar N, Roy A, Sengupta A, Roy B, Panda CK, Roychoudhury S (2003) Allelic imbalance at chromosome 11 in head and neck squamous cell carcinoma in an Indian patient population. J Clin Pathol 56:512-518
28. Munger K, Heselmeyer K (1999) The molecular pathogenesis of cervical cancer: the role of human papillomavirus. In: Srivatsava S et al. (eds) Molecular pathology of early cancer. IOS, pp 97-111
29. Narayan G, Pulido HA, Koul S, Lu XY, Harris CP, Yeh YA, Vargas H, Posso H, Terry MB, Gissmann L, Schneider A, Mansukhani M, Rao PH, Murty VVVS (2002) Genetic analysis identifies putative tumor suppressor sites at 2q35-q36.1 and 2q36.3-q37.1 involved in cervical cancer progression. Oncogene 22:3489-3499
30. Park JS, Dong SM, Kim HS, Lee JY, Um SJ, Park IS, Kim SJ, Namkoong SF (1999) Detection of p16 gene alteration in cervical cancer using tissue microdissection and LOH study. Cancer Lett 136:101-108
31. Perucca-Lostanlen D, Hecht BK, Courseaux A, Grosgeorge J, Hecht F, Gaudray P (1997) Mapping of FRA11A, a folate-sensitive fragile site in human chromosome band 11q13.3. Cytogenet Cell Genet 79:88-91
32. Pulido HA, Fakruddin MJ, Chatterjee A, Esplin ED, Beleno N, Martinez G, Posso H, Evans GA, Murty VVVS (2000) Identification of a 6-cM minimal deletion at 11q23.1-23.2 and exclusion of PPP2R1B gene as a deletion target in cervical cancer. Cancer Res 60:6677-6682
33. Rabbits PH, Douglas J, Fisher P, Nacheva E, Karpas A, Catovsky D, Melo JV, Baer R, Stinson MA, Rabbits TH (1988) Chromosome abnormalities at 11q13 in B-cell tumors. Oncogene 3:99-103
34. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor, NY
35. Saxon PJ, Srivatsan ES, Stanbridge (1986) Introduction of human chromosome 11 via micro-cell transfer controls tumorigenic expression of HeLa cells. EMBO J 5:3461-3466
36. Schiffman MH, Brinton LA (1995) The Epidemiology of cervical carcinogenesis. Cancer [Supp] 76:1888-1897
37. Schuuring E, Verhoeven E, Mooi WJ, Michalides RJAM (1992) Identification and cloning of two overexpressed genes, U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas Oncogene 7:355-361
38. Schwab M (1998) Amplification of oncogenes in human cancer cells. Bioessays 20:473-479
39. Sen U, Sankaranarayanan R, Mandal S, Ramanakumar AV, Parkin DM, Siddiqi M (2002) Cancer patterns in eastern India: the first report of the Kolkata cancer registry. Int J Cancer 100:86-91
40. Shanta V, Krishnamurthi S, Gajalakshmi CK, Swaminathan R, Ravichandran K (2000) Epidemiology of cancer of the cervix: global and national perspective. J Indian Med Assoc 98:49-52
41. Shuster Ml, Han L, Le Beau MM, Davis E, Sawicki MP, Lese CM, Park NH, Colicelli J, Gollin S (2000) A consistent pattern of RIN 1 rearrangement in oral squamous cell carcinoma cell lines supports a breakage-fusion- bridge cycle model for 11q13 amplification. Genes Chromosomes Cancer 28:153-163
42. Skomedal H, Helland A, Kristensen GB, Holm R, Dale ALB (1999) Allelic imbalance at chromosome region 11q23 in cervical carcinomas. Eur J Cancer 35:659-663
43. Smits PH, Smits HL, Jebbink MF, ter Schegget J (1990) The short arm of chromosome 11 likely is involved in the regulation of the human papilloma virus type -16 early enhancer-promoter and in the suppression of the transforming activity of the viral DNA. Virology 176:158-165
44. Srivatsan ES, Chakrabarti R, Zainabadi K, Pack SD, Benyamini P, Mendonca MS, Yang PK, Kang K, Motamedi D, Sawicki MP, Zhuang Z, Jesudasan RA, Bengtsson U, Sun C, Roe BA, Stanbridge EJ, Wilczynski SP, Redpath JL (2002) Localization of deletion to a 300 Kb interval of chromosome 11q13 in cervical cancer. Oncogene 21:5631-5642
45. Steenbergen RDM, Kramer D, Braakhuis BJM, Stern PL, Verheijen RHM, Meijer CJLM, Snijders PJF (2004) TSLC1 Gene silencing in cervical cancer cell lines and cervical neoplasia. J Natl Cancer Inst 96:294-305
46. Tavani A, Negri E, La Vecchia C (1996) Menstrual and reproductive factors and biliary tract cancers. Eur J Cancer Prev 5:241-247
47. The genome browser gateway (http://genome.ucsc.edu/cgi-bin/ hgGateway)
48. The Genome Database (http://www.gdb.org)
49. Tripathi A, Banerjee S, Chunder N, Roy A, Sengupta A, Roy B, Roychowdhury S, Panda CK (2003a) Differential alterations of the genes in the CDKN2A- CCND1- CDK4-RB1 pathway are associated with the development of head and neck squamous cell carcinoma in Indian patients. J Cancer Res Clin Oncol 129:642-650
50. Tripathi A, Banerjee S, Roy A, Roychowdhury S, Panda CK (2003b) Alteration of p16 gene in uterine cervical carcinoma from Indian patients. Int J Gynecol Cancer 13:472-479
51. Zhang A, Maner S, Betz R, Angstrom T, Stendahl U, Bergman F, Zetterberg A, Wallin K (2002) Genetic alterations in cervical carcinomas: frequent low level amplifications of oncogenes are associated with human papillomavirus infection. Int J Cancer 101:427-433
52. Zur Hausen H (1996) Papillomavirus infection - major cause of human cancers. Biochem Biophys Acta 1288:55-78