Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2β protein: Implications in cross-reactivity

PLoS Neglected Tropical Diseases

Volumn 5, Issue 11, 2011, Pages

  Pizarro, Juan Carlos ^a,b,e   Boulot, Ginette ^a,b   Bentley, Graham A ^a,b   Gómez, Karina A ^c   Hoebeke, Johan ^d   Hontebeyrie, Mireille ^a   Levin, Mariano J ^c   Smulski, Cristian R ^c,d  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c INSTITUTO DE INVESTIGACIONES EN INGENIERÍA GENÉTICA Y BIOLOGÍA MOLECULAR   (Argentina)

^d CNRS UPR9021   (France)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; BETA 1 ADRENERGIC RECEPTOR; CARBOXY TERMINAL TELOPEPTIDE; EPITOPE; GLUTAMIC ACID; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 17.2; PHENYLALANINE; PROTEIN P2B; PROTEIN R13; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG; IMMUNOGLOBULIN F(AB) FRAGMENT; PHOSPHOPROTEIN; PHOSPHOPROTEIN P2, RIBOSOMAL; PROTOZOON ANTIBODY; RIBOSOME PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATRIOVENTRICULAR BLOCK; CHAGAS DISEASE; CONTROLLED STUDY; CROSS REACTION; CRYSTAL STRUCTURE; FEMALE; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPOLARIZATION; STRUCTURE ANALYSIS; TRYPANOSOMA CRUZI; ANIMAL; BAGG ALBINO MOUSE; CHEMICAL STRUCTURE; CHEMISTRY; IMMUNOLOGY; METABOLISM; PROTEIN BINDING; PROTEIN QUATERNARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, PROTOZOAN; CROSS REACTIONS; CRYSTALLOGRAPHY, X-RAY; FEMALE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, ADRENERGIC, BETA-1; RIBOSOMAL PROTEINS; TRYPANOSOMA CRUZI;

EID: 82555169268     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001375     Document Type: Article

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