Enantioselective effects of alpha-hexachlorocyclohexane (HCH) isomers on androgen receptor activity in vitro

Chemosphere

Volumn 86, Issue 1, 2012, Pages 65-69

  Pavlíková, Nela ^a   Bláhová, Lucie ^a   Klán, Petr ^a   Bathula, Sreenivas Reddy ^a   Sklenář, Vladimír ^a   Giesy, John P ^b,c,d   Bláha, Ludek ^a  

^a MASARYK UNIVERSITY   (Czech Republic)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d CITY UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Anti androgenicity; Hexachlorocyclohexane; Optical isomers; Pesticide

Indexed keywords

CELL CULTURE; ENANTIOMERS; ENANTIOSELECTIVITY; FREE ENERGY; ORGANIC POLLUTANTS; PESTICIDES; TOXICITY;

ANTI-ANDROGENICITY; CONCENTRATION-DEPENDENT MANNERS; ENANTIOSELECTIVE EFFECTS; FREE ENERGY OF BINDING; HEXACHLOROCYCLOHEXANE ISOMERS; HEXACHLOROCYCLOHEXANES; OPTICAL ISOMERS; PERSISTENT ORGANIC POLLUTANT (POP);

PLANTS (BOTANY);

3,4 METHYLENEDIOXYAMPHETAMINE; ALPHA HEXACHLOROCYCLOHEXANE; ANDROGEN RECEPTOR; ANDROSTANOLONE; LIGAND; LUCIFERASE;

ANDROGEN; CHEMICAL BINDING; CONCENTRATION (COMPOSITION); HCH; INHIBITION; LIGAND; LIQUID CHROMATOGRAPHY; ORGANIC POLLUTANT; PERSISTENCE; PESTICIDE; POLLUTION EFFECT; TOXICOLOGY;

ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CELL ACTIVITY; CONTROLLED STUDY; ENANTIOMER; ENANTIOSELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR MODEL; REPORTER GENE;

EID: 82555166001     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2011.08.052     Document Type: Article

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