Enantioselective estrogenicity of o,p'-dichlorodiphenyltrichloroethane in the MCF-7 human breast carcinoma cell line

Environmental Toxicology and Chemistry

Volumn 28, Issue 1, 2009, Pages 1-8

  Wang, Lumei ^a   Zhou, Shanshan ^a   Lin, Kunde ^b   Zhao, Meirong ^b   Liu, Weiping ^a,b   Gan, Jianying ^c  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell proliferation; Enantioselectivity; Endocrine disruption; Gene expression; o,p' dichlorodiphenyltrichloroethane

Indexed keywords

ABSOLUTE CONFIGURATION; BASELINE SEPARATION; CHIRAL COLUMN; CONCENTRATION OF; DICHLORODIPHENYLTRICHLOROETHANE; DOWN-REGULATION; E-SCREEN; ECOLOGICAL TOXICITY; ENANTIOSELECTIVE; ENDOCRINE DISRUPTION; ESTROGEN RECEPTOR; ESTROGENICITY; HUMAN BREAST; HUMAN BREAST CARCINOMA CELLS; MCF-7 CELLS; MRNA LEVEL; O,P'- DICHLORODIPHENYLTRICHLOROETHANE; PROLIFERATIVE EFFECTS; QUANTITATIVE POLYMERASE CHAIN REACTION; SIGNALING PATHWAYS; SOLVENT CONTROL; TOXICOLOGICAL EFFECTS; TRANSCRIPTION LEVEL; UP-REGULATION;

BIOACTIVITY; CELL CULTURE; CELL PROLIFERATION; CHIRALITY; CHROMATOGRAPHIC ANALYSIS; COLUMN CHROMATOGRAPHY; ELECTRON TRANSITIONS; ENANTIOMERS; ENANTIOSELECTIVITY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; OPTICAL ROTATION; POLYMERASE CHAIN REACTION; TOXICITY; TRANSCRIPTION;

GENE EXPRESSION REGULATION;

2,4' DICHLORODIPHENYLTRICHLOROETHANE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ORGANOCHLORINE DERIVATIVE; PROTEIN PS2; UNCLASSIFIED DRUG; 1,1,1 TRICHLORO 2 (2 CHLOROPHENYL) 2 (4 CHLOROPHENYL)ETHANE; CHLORPHENOTANE; ESTROGEN; O,P'-DDT; PRIMER DNA;

BIOASSAY; BIOMARKER; CANCER; CHROMATOGRAPHY; DDT; ENDOCRINE DISRUPTOR; ESTROGENIC COMPOUND; GENE EXPRESSION; POLLUTION EFFECT; POLYMERASE CHAIN REACTION; PUBLIC HEALTH; TOXICOLOGY;

ARTICLE; CELL PROLIFERATION; CELL STRAIN MCF 7; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENANTIOMER; ENANTIOSELECTIVITY; ESTROGEN ACTIVITY; HUMAN; HUMAN CELL; OPTICAL ROTATION; PRIORITY JOURNAL; RACEMIC MIXTURE; RECEPTOR DOWN REGULATION; STRUCTURE ANALYSIS; UPREGULATION; BREAST TUMOR; CHEMISTRY; DRUG EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEOTIDE SEQUENCE; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEREOISOMERISM; TUMOR CELL LINE;

BASE SEQUENCE; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DDT; DNA PRIMERS; ESTROGENS; HUMANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEREOISOMERISM;

EID: 65449158134     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1897/08-055.1     Document Type: Article

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