Angiogenesis and proteinases: Influence on vascular morphogenesis, stabilization and regression

Drug Discovery Today: Disease Models

Volumn 8, Issue 1, 2011, Pages 13-20

  Davis, George E ^a,b  

^a UNIVERSITY OF MISSOURI   (United States)

^b University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 4; ENTACTIN; FIBRONECTIN; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; INTERSTITIAL COLLAGENASE; LAMININ; MATRIX METALLOPROTEINASE; PERLECAN; PLASMINOGEN ACTIVATOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLATELET DERIVED GROWTH FACTOR BB; PROTEINASE; PROTEINASE INHIBITOR; STROMELYSIN 2; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; VASCULOTROPIN D; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ARTICLE; BASEMENT MEMBRANE; BLOOD VESSEL; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MORPHOGENESIS; PERICYTE;

EID: 82455192222     PISSN: None     EISSN: 17406757     Source Type: Journal    
DOI: 10.1016/j.ddmod.2011.03.004     Document Type: Review

References (68)

1. Apte, S. S. (2009) A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms. J. Biol. Chem. 284, 31493-31497
2. Arroyo, A. G. and Iruela-Arispe, M. L. (2010) Extracellular matrix, inflammation, and the angiogenic response. Cardiovasc. Res. 86, 226-235
3. Binder, B. R. et al. (2007) uPAR-uPA-PAI-1 interactions and signaling: a vascular biologist's view. Thromb. Haemost. 97, 336-342 (Pubitemid 46437793)
4. Blobel, C. P. (2005) ADAMs: key components in EGFR signalling and development. Nat. Rev. Mol. Cell Biol. 6, 32-43 (Pubitemid 40064897)
5. Castellino, F. J. and Ploplis, V. A. (2005) Structure and function of the plasminogen/plasmin system. Thromb. Haemost. 93, 647-654 (Pubitemid 40485399)
6. Coughlin, S. R. (2005) Protease-activated receptors in hemostasis, thrombosis and vascular biology. J. Thromb. Haemost. 3, 1800-1814 (Pubitemid 41716567)
7. Davis, G. E. and Saunders, W. B. (2006) Molecular balance of capillary tube formation versus regression in wound repair: role of matrix metalloproteinases and their inhibitors. J. Investig. Dermatol. Symp. Proc. 11, 44-56 (Pubitemid 44413144)
8. Porter, S. et al. (2005) The ADAMTS metalloproteinases. Biochem. J. 386, 15-27
9. Sabeh, F. et al. (2009) Protease-dependent versus-independent cancer cell invasion programs: three-dimensional amoeboid movement revisited. J. Cell Biol. 185, 11-19
10. van Hinsbergh, V. W. and Koolwijk, P. (2008) Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead. Cardiovasc. Res. 78, 203-212 (Pubitemid 351556093)
11. Davis, G. E. (2010) Matricryptic sites control tissue injury responses in the cardiovascular system: relationships to pattern recognition receptor regulated events. J. Mol. Cell. Cardiol. 48, 454-460
12. Adams, R. H. and Alitalo, K. (2007) Molecular regulation of angiogenesis and lymphangiogenesis. Nat. Rev. Mol. Cell Biol. 8, 464-478 (Pubitemid 46823443)
13. Davis, G. E. et al. Molecular basis for endothelial lumen formation and tubulogenesis during vasculogenesis and angiogenic sprouting. Int. Rev. Cell. Mol. Biol. (in press)
14. Senger, D. R. and Davis, G. E. Angiogenesis. Cold Spring Harb. Perspect. Biol. (in press)
15. Davis, G. E. and Senger, D. R. (2005) Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization. Circ. Res. 97, 1093-1107
16. Hynes, R. O. (2009) The extracellular matrix: not just pretty fibrils. Science 326, 1216-1219
17. Davis, G. E. et al. (2007) Mechanisms controlling human endothelial lumen formation and tube assembly in three-dimensional extracellular matrices. Birth Defects Res. C: Embryo Today 81, 270-285 (Pubitemid 351186175)
18. Gonzalo, P. et al. (2010) MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling. Dev. Cell 18, 77-89
19. Seo, D. W. et al. (2003) TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism. Cell 114, 171-180
20. Stetler-Stevenson, W. G. and Seo, D. W. (2005) TIMP-2: an endogenous inhibitor of angiogenesis. Trends Mol. Med. 11, 97-103 (Pubitemid 40348986)
21. Chun, T. H. et al. (2004) MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix. J. Cell Biol. 167, 757-767
22. Sacharidou, A. et al. (2010) Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through interdependent Cdc42- and MT1-MMP-mediated events. Blood 115, 5259-5269
23. Saunders, W. B. et al. (2006) Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. J. Cell Biol. 175, 179-191 (Pubitemid 44537209)
24. Stratman, A. N. et al. (2009) Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3- dimensional collagen matrices. Blood 114, 237-247
25. Bergers, G. et al. (2000) Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat. Cell Biol. 2, 737-744
26. Haas, T. L. and Madri, J. A. (1999) Extracellular matrix-driven matrix metalloproteinase production in endothelial cells: implications for angiogenesis. Trends Cardiovasc. Med. 9, 70-77 (Pubitemid 29512239)
27. Zhou, Z. et al. (2000) Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I. Proc. Natl. Acad. Sci. U. S. A. 97, 4052-4057 (Pubitemid 30226085)
28. Stratman, A. N. et al. (2009) Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood 114, 5091-5101
29. Lee, S. et al. (2005) Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J. Cell Biol. 169, 681-691 (Pubitemid 41002860)
30. Ardi, V. C. et al. (2007) Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis. Proc. Natl. Acad. Sci. U. S. A. 104, 20262-20267
31. Heissig, B. et al. (2010) Role of neutrophil-derived matrix metalloproteinase-9 intissue regeneration. Histol. Histopathol. 25, 765-770
32. Luque, A. et al. (2003) ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165. J. Biol. Chem. 278, 23656-23665 (Pubitemid 36830188)
33. Chen, T. T. et al. (2010) Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells. J. Cell Biol. 188, 595-609
34. Horiuchi, K. et al. (2003) Potential role for ADAM15 in pathological neovascularization in mice. Mol. Cell. Biol. 23, 5614-5624 (Pubitemid 36951327)
35. Weskamp, G. et al. (2010) Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells but not in pericytes. Circ. Res. 106, 932-940
36. Swendeman, S. et al. (2008) VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling. Circ. Res. 103, 916-918
37. Hartmann, D. et al. (2002) The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts. Hum. Mol. Genet. 11, 2615-2624 (Pubitemid 35174691)
38. Sainson, R. C. et al. (2005) Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis. FASEB J. 19, 1027-1029 (Pubitemid 40827740)
39. Shi, G. P. et al. (2003) Deficiency of the cysteine protease cathepsin S impairs microvessel growth. Circ. Res. 92, 493-500
40. Chang, S. H. et al. (2009) VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Res. 69, 4537-4544
41. Joyce, J. A. et al. (2004) Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell 5, 443-453 (Pubitemid 38610246)
42. Frears, E. R. et al. (1996) Inactivation of tissue inhibitor of metalloproteinase-1 by peroxynitrite. FEBS Lett. 381, 21-24 (Pubitemid 26070416)
43. Itoh, Y. and Nagase, H. (1995) Preferential inactivation of tissue inhibitor of metalloproteinases-1 that is bound to the precursor of matrix metalloproteinase 9 (progelatinase B) by human neutrophil elastase. J. Biol. Chem. 270, 16518-16521
44. Saunders, W. B. et al. (2005) MMP-1 activation by serine proteases and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices. J. Cell Sci. 118, 2325-2340 (Pubitemid 40872853)
45. Bayless, K. J. and Davis, G. E. (2004) Microtubule depolymerization rapidly collapses capillary tube networks in vitro and angiogenic vessels in vivo through the small GTPase Rho. J. Biol. Chem. 279, 11686-11695 (Pubitemid 38401672)
46. Garcia, J. G. et al. (1996) Regulation of thrombin-mediated endothelial cell contraction and permeability. Semin. Thromb. Hemost. 22, 309-315 (Pubitemid 26414408)
47. Drinane, M. et al. (2006) The anti-angiogenic activity of rPAI-1 (23) inhibits fibroblast growth factor-2 functions. J. Biol. Chem. 281, 33336-33344 (Pubitemid 46036715)
48. Raffetto, J. D. and Khalil, R. A. (2008) Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. Biochem. Pharmacol. 75, 346-359 (Pubitemid 350298459)
49. Davis, G. E. et al. (2001) Matrix metalloproteinase-1 and-9 activation by plasmin regulates a novel endothelial cell-mediated mechanism of collagen gel contraction and capillary tube regression in three dimensional collagen matrices. J. Cell Sci. 114, 917-930
50. Zhu, W. H. et al. (2000) Regulation of vascular growth and regression by matrix metalloproteinases in the rat aorta model of angiogenesis. Lab. Invest. 80, 545-555
51. Noel, A. et al. (2004) Membrane associated proteases and their inhibitors in tumour angiogenesis. J. Clin. Pathol. 57, 577-584 (Pubitemid 38725756)
52. Yamada, E. et al. (2001) TIMP-1 promotes VEGF-induced neovascularization in the retina. Histol. Histopathol. 16, 87-97 (Pubitemid 32094026)
53. Chang, S. et al. (2006) Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell 126, 321-334 (Pubitemid 44092958)
54. Khokha, R. and Werb, Z. Mammary gland reprogramming: metalloproteinases couple form with function. Cold Spring Harb. Perspect. Biol. (in press)
55. Zhang, X. and Nothnick, W. B. (2005) The role and regulation of the uterine matrix metalloproteinase system in menstruating and nonmenstruating species. Front. Biosci. 10, 353-366 (Pubitemid 40552764)
56. DeLano, F. A. and Schmid-Schonbein, G. W. (2008) Proteinase activity and receptor cleavage: mechanism for insulin resistance in the spontaneously hypertensive rat. Hypertension 52, 415-423
57. Tran, E. D. et al. (2010) Enhanced matrix metalloproteinase activity in the spontaneously hypertensive rat: VEGFR-2 cleavage, endothelial apoptosis, and capillary rarefaction. J. Vasc. Res. 47, 423-431
58. Isenberg, J. S. et al. (2008) Thrombospondin-1: a physiological regulator of nitric oxide signaling. Cell. Mol. Life Sci. 65, 728-742
59. Isenberg, J. S. et al. (2007) Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide-mediated vascular smooth muscle relaxation. Blood 109, 1945-1952 (Pubitemid 46348191)
60. Isenberg, J. S. et al. (2009) Regulation of nitric oxide signalling by thrombospondin 1: implications for anti-angiogenic therapies. Nat. Rev. Cancer 9, 182-194
61. Guaiquil, V. et al. (2009) ADAM9 is involved in pathological retinal neovascularization. Mol. Cell. Biol. 29, 2694-2703
62. Benjamin, L. E. et al. (1998) Aplasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 125, 1591-1598 (Pubitemid 28256727)
63. Brew, K. and Nagase, H. (2010) The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity. Biochim. Biophys. Acta 1803, 55-71
64. Qi, J. H. et al. (2003) A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat. Med. 9, 407-415 (Pubitemid 36460074)
65. Stratman, A. N. et al. (2010) Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization. Blood 116, 4720-4730
66. Hynes, R. O. (2007) Cell-matrix adhesion in vascular development. J. Thromb. Haemost. Suppl. 1, 32-40 (Pubitemid 46964284)
67. Bergsten, E. et al. (2001) PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor. Nat. Cell Biol. 3, 512-516 (Pubitemid 32422089)
68. McColl, B. K. et al. (2003) Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D. J. Exp. Med. 198, 863-868 (Pubitemid 37152923)