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Volumn 12, Issue , 2011, Pages

Identification of dysfunctional modules and disease genes in congenital heart disease by a network-based approach

Author keywords

[No Author keywords available]

Indexed keywords

JAGGED1; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE 7; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; PROTEIN FOS; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6; TRANSCRIPTION FACTOR NKX2.5;

EID: 82455188358     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-12-592     Document Type: Article
Times cited : (45)

References (48)
  • 1
    • 34250305402 scopus 로고    scopus 로고
    • Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics
    • Pierpont ME, Basson CT, Benson DW, Gelb BD, Giglia TM, Goldmuntz E, McGee G, Sable CA, Srivastava D, Webb CL, et al. Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics. Circulation Research 2007, 115(23):3015-3038.
    • (2007) Circulation Research , vol.115 , Issue.23 , pp. 3015-3038
    • Pierpont, M.E.1    Basson, C.T.2    Benson, D.W.3    Gelb, B.D.4    Giglia, T.M.5    Goldmuntz, E.6    McGee, G.7    Sable, C.A.8    Srivastava, D.9    Webb, C.L.10
  • 2
    • 77957601615 scopus 로고    scopus 로고
    • Genetic factors in non-sunbdormic congenital heart malformations
    • 10.1111/j.1399-0004.2010.01435.x, 20497191
    • Wessels MW, Willems PJ. Genetic factors in non-sunbdormic congenital heart malformations. Clinical Genetics 2010, 78:103-123. 10.1111/j.1399-0004.2010.01435.x, 20497191.
    • (2010) Clinical Genetics , vol.78 , pp. 103-123
    • Wessels, M.W.1    Willems, P.J.2
  • 3
    • 39749191367 scopus 로고    scopus 로고
    • The developmental genetics of congential heart disease
    • Bruneau BG. The developmental genetics of congential heart disease. Nature Insight Review 2008, 451(7181):943-948.
    • (2008) Nature Insight Review , vol.451 , Issue.7181 , pp. 943-948
    • Bruneau, B.G.1
  • 4
    • 77952511899 scopus 로고    scopus 로고
    • From molecular mechanisms of cardiac development to genetic substrate of congenital heart diseases
    • 10.2217/fca.10.10, 20462343
    • Cecchetto A, Rampazzo A, Angelini A, Bianco LD, Padalino M, Stellin G, Daliento L. From molecular mechanisms of cardiac development to genetic substrate of congenital heart diseases. Future Cardiol 2010, 6(3):373-393. 10.2217/fca.10.10, 20462343.
    • (2010) Future Cardiol , vol.6 , Issue.3 , pp. 373-393
    • Cecchetto, A.1    Rampazzo, A.2    Angelini, A.3    Bianco, L.D.4    Padalino, M.5    Stellin, G.6    Daliento, L.7
  • 9
    • 77955471305 scopus 로고    scopus 로고
    • Transcriptomic analysis of patients with tetralogy of Fallot reveals the effect of chronic hypoxia on myocardial gene expression
    • 10.1016/j.jtcvs.2009.12.055, 2951593, 20416888
    • Ghorbel MT, Cherif M, Jenkins E, Mokhtari A, Kenny D, Angelini GD, Caputo M. Transcriptomic analysis of patients with tetralogy of Fallot reveals the effect of chronic hypoxia on myocardial gene expression. J Thorac Cardiovasc Surg 2010, 140(2):337-345. 10.1016/j.jtcvs.2009.12.055, 2951593, 20416888.
    • (2010) J Thorac Cardiovasc Surg , vol.140 , Issue.2 , pp. 337-345
    • Ghorbel, M.T.1    Cherif, M.2    Jenkins, E.3    Mokhtari, A.4    Kenny, D.5    Angelini, G.D.6    Caputo, M.7
  • 10
    • 42949096140 scopus 로고    scopus 로고
    • EQED: an efficient method for interpreting eQTL associations using protein networks
    • Suthram S, Beyer A, Karp RM, Eldar Y, Ideker T. eQED: an efficient method for interpreting eQTL associations using protein networks. Molecular Systems Biology 2008, 4(162).
    • (2008) Molecular Systems Biology , vol.4 , Issue.162
    • Suthram, S.1    Beyer, A.2    Karp, R.M.3    Eldar, Y.4    Ideker, T.5
  • 11
    • 79953645463 scopus 로고    scopus 로고
    • Identifying causal genes and dysregulated pathways in complex diseases
    • 10.1371/journal.pcbi.1001095, 3048384, 21390271
    • Kim YA, Wuchty S, Przytycka TM. Identifying causal genes and dysregulated pathways in complex diseases. PLoS Comput Biol 2011, 7(3):e1001095. 10.1371/journal.pcbi.1001095, 3048384, 21390271.
    • (2011) PLoS Comput Biol , vol.7 , Issue.3
    • Kim, Y.A.1    Wuchty, S.2    Przytycka, T.M.3
  • 14
    • 0003252136 scopus 로고    scopus 로고
    • Random walks and electric networks
    • Doyle PG, Snell J. Random walks and electric networks. Am Math Mon 2000, 94:202.
    • (2000) Am Math Mon , vol.94 , pp. 202
    • Doyle, P.G.1    Snell, J.2
  • 15
    • 66249092826 scopus 로고    scopus 로고
    • Information Flow Analysis of Interactome Networks
    • 10.1371/journal.pcbi.1000350, 2685719, 19503817
    • Missiuro PV, Liu K, Zou L, Ross BC, Zhao G, Liu JS, Ge H. Information Flow Analysis of Interactome Networks. PLoS Comput Biol 2009, 5(4):e1000350. 10.1371/journal.pcbi.1000350, 2685719, 19503817.
    • (2009) PLoS Comput Biol , vol.5 , Issue.4
    • Missiuro, P.V.1    Liu, K.2    Zou, L.3    Ross, B.C.4    Zhao, G.5    Liu, J.S.6    Ge, H.7
  • 16
    • 70350452746 scopus 로고    scopus 로고
    • Integrating proteomic, transcriptional, and interactome data reveals hidden components of signaling and regulatory networks
    • 10.1126/scisignal.2000350, 2889494, 19638617
    • Huang SS, Fraenkel E. Integrating proteomic, transcriptional, and interactome data reveals hidden components of signaling and regulatory networks. Sci Signal 2009, 2(81):ra40. 10.1126/scisignal.2000350, 2889494, 19638617.
    • (2009) Sci Signal , vol.2 , Issue.81
    • Huang, S.S.1    Fraenkel, E.2
  • 17
    • 77954474131 scopus 로고    scopus 로고
    • A systems-biology approach to modular genetic complexity
    • 10.1063/1.3455183, 2909309, 20590331
    • Carter GW, Rush CG, Uygun F, Sakhanenko NA, Galas DJ, Galitski T. A systems-biology approach to modular genetic complexity. Chaos 2010, 20(2):026102. 10.1063/1.3455183, 2909309, 20590331.
    • (2010) Chaos , vol.20 , Issue.2 , pp. 026102
    • Carter, G.W.1    Rush, C.G.2    Uygun, F.3    Sakhanenko, N.A.4    Galas, D.J.5    Galitski, T.6
  • 18
    • 0003535936 scopus 로고
    • Categorical data analysis
    • John Wiley & Sons
    • Agresti A. Categorical data analysis. 1990, John Wiley & Sons.
    • (1990)
    • Agresti, A.1
  • 19
    • 3042514191 scopus 로고    scopus 로고
    • Coexpression Analysis of Human Genes Across Many Microarray Data Sets
    • 10.1101/gr.1910904, 419787, 15173114
    • Lee HK, Hsu AK, Sajdak J, Qin J, Pavlidis P. Coexpression Analysis of Human Genes Across Many Microarray Data Sets. Genome Res 2004, 14:1085-1094. 10.1101/gr.1910904, 419787, 15173114.
    • (2004) Genome Res , vol.14 , pp. 1085-1094
    • Lee, H.K.1    Hsu, A.K.2    Sajdak, J.3    Qin, J.4    Pavlidis, P.5
  • 20
    • 80052215666 scopus 로고    scopus 로고
    • NOA: a novel Network Ontology Analysis method
    • 10.1093/nar/gkr251, 3141273, 21543451
    • Wang J, Huang Q, Liu ZP, Wang Y, Wu LY, Chen L, Zhang XS. NOA: a novel Network Ontology Analysis method. Nucl Acids Res 2011, 39(13):e87. 10.1093/nar/gkr251, 3141273, 21543451.
    • (2011) Nucl Acids Res , vol.39 , Issue.13
    • Wang, J.1    Huang, Q.2    Liu, Z.P.3    Wang, Y.4    Wu, L.Y.5    Chen, L.6    Zhang, X.S.7
  • 23
    • 50849104527 scopus 로고    scopus 로고
    • NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling
    • 10.1093/hmg/ddn187, 2722892, 18593716
    • McBride K, Riley MF, Zender GA. NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling. Hum Mol Genet 2008, 17:2886-2893. 10.1093/hmg/ddn187, 2722892, 18593716.
    • (2008) Hum Mol Genet , vol.17 , pp. 2886-2893
    • McBride, K.1    Riley, M.F.2    Zender, G.A.3
  • 24
    • 0033531963 scopus 로고    scopus 로고
    • Jagged1 mutations in patients ascertained with isolated congenital heart defects
    • 10.1002/(SICI)1096-8628(19990507)84:1<56::AID-AJMG11>3.0.CO;2-W, 10213047
    • Krantz ID, Smith R, Colliton RP, Tinkel H, Zackai EH, Piccoli DA, Goldmuntz E, Spinner NB. Jagged1 mutations in patients ascertained with isolated congenital heart defects. Am J Med Genet 1999, 84(1):56-60. 10.1002/(SICI)1096-8628(19990507)84:1<56::AID-AJMG11>3.0.CO;2-W, 10213047.
    • (1999) Am J Med Genet , vol.84 , Issue.1 , pp. 56-60
    • Krantz, I.D.1    Smith, R.2    Colliton, R.P.3    Tinkel, H.4    Zackai, E.H.5    Piccoli, D.A.6    Goldmuntz, E.7    Spinner, N.B.8
  • 27
    • 0035828196 scopus 로고    scopus 로고
    • Identification of connexin 43 (alpha1) gap junction gene mutations in patients with hypoplastic left heart syndrome by denaturing gradient gel electrophoresis (DGGE)
    • Dasgupta C, Martinez AM, Zuppan CW, Shah MM, Bailey LL, Fletcher WH. Identification of connexin 43 (alpha1) gap junction gene mutations in patients with hypoplastic left heart syndrome by denaturing gradient gel electrophoresis (DGGE). Mutat Res 2001, 479(1-2):173-186.
    • (2001) Mutat Res , vol.479 , Issue.1-2 , pp. 173-186
    • Dasgupta, C.1    Martinez, A.M.2    Zuppan, C.W.3    Shah, M.M.4    Bailey, L.L.5    Fletcher, W.H.6
  • 30
    • 43049105408 scopus 로고    scopus 로고
    • A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts
    • 10.1093/hmg/ddn027, 18276607
    • Reamon-Buettner SM, Ciribilli Y, Inga A, Borlak J. A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts. Hum Mol Genet 2008, 17(10):1397-1405. 10.1093/hmg/ddn027, 18276607.
    • (2008) Hum Mol Genet , vol.17 , Issue.10 , pp. 1397-1405
    • Reamon-Buettner, S.M.1    Ciribilli, Y.2    Inga, A.3    Borlak, J.4
  • 31
    • 0141764868 scopus 로고    scopus 로고
    • A HANDful of questions: the molecular biology of the heart and neural crest derivatives (HAND)-subclass of basic helix-loop-helix transcription factors
    • Firulli AB. A HANDful of questions: the molecular biology of the heart and neural crest derivatives (HAND)-subclass of basic helix-loop-helix transcription factors. Gene 2003, 17(312):27-40.
    • (2003) Gene , vol.17 , Issue.312 , pp. 27-40
    • Firulli, A.B.1
  • 32
    • 0030903857 scopus 로고    scopus 로고
    • Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND
    • 10.1038/ng0697-154, 9171826
    • Srivastava D, Thomas T, Lin Q, Kirby ML, Brown D, Olson EN. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat Genet 1997, 16(2):154-160. 10.1038/ng0697-154, 9171826.
    • (1997) Nat Genet , vol.16 , Issue.2 , pp. 154-160
    • Srivastava, D.1    Thomas, T.2    Lin, Q.3    Kirby, M.L.4    Brown, D.5    Olson, E.N.6
  • 33
    • 77954471994 scopus 로고    scopus 로고
    • Transcription factor HAND2 mutations in sporadic Chinese patients with congenital heart disease
    • Shen L, Li XF, Shen AD, Wang Q, Liu CX, Guo YJ, Song ZJ, Li ZZ. Transcription factor HAND2 mutations in sporadic Chinese patients with congenital heart disease. Chin Med J (Engl) 2010, 123(13):1623-1627.
    • (2010) Chin Med J (Engl) , vol.123 , Issue.13 , pp. 1623-1627
    • Shen, L.1    Li, X.F.2    Shen, A.D.3    Wang, Q.4    Liu, C.X.5    Guo, Y.J.6    Song, Z.J.7    Li, Z.Z.8
  • 35
    • 33745232796 scopus 로고    scopus 로고
    • NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway
    • 10.1086/505332, 1474136, 16773578
    • McDaniell R, Warthen DM, Sanchez-Lara PA, Pai AKI, Piccoli DA, Spinner NB. NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway. Am J Hum Genet 2006, 79(1):169-173. 10.1086/505332, 1474136, 16773578.
    • (2006) Am J Hum Genet , vol.79 , Issue.1 , pp. 169-173
    • McDaniell, R.1    Warthen, D.M.2    Sanchez-Lara, P.A.3    Pai, A.K.I.4    Piccoli, D.A.5    Spinner, N.B.6
  • 37
    • 0037172948 scopus 로고    scopus 로고
    • Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents
    • 10.1073/pnas.132275199, 124375, 12077312
    • Birrell GW, Brown JA, Wu HI, Giaever G, Chu AM, Davis RW, Brown JM. Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents. Proc Natl Acad Sci USA 2002, 99(13):8778-8783. 10.1073/pnas.132275199, 124375, 12077312.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.13 , pp. 8778-8783
    • Birrell, G.W.1    Brown, J.A.2    Wu, H.I.3    Giaever, G.4    Chu, A.M.5    Davis, R.W.6    Brown, J.M.7
  • 46
    • 57149092133 scopus 로고    scopus 로고
    • Inferring Pathway Activity toward Precise Disease Classification
    • 10.1371/journal.pcbi.1000217, 2563693, 18989396
    • Lee E, Chuang H-Y, Kim J-W, Ideker T, Lee D. Inferring Pathway Activity toward Precise Disease Classification. PLoS Comput Biol 2008, 4(11):e1000217. 10.1371/journal.pcbi.1000217, 2563693, 18989396.
    • (2008) PLoS Comput Biol , vol.4 , Issue.11
    • Lee, E.1    Chuang, H.-.Y.2    Kim, J.-.W.3    Ideker, T.4    Lee, D.5
  • 48
    • 77956850355 scopus 로고    scopus 로고
    • Identifying dysfunctional crosstalk of pathways in various regions of Alzheimer's disease brains
    • 10.1186/1752-0509-4-S2-S11, 2982685, 20840725
    • Liu ZP, Wang Y, Zhang XS, Chen L. Identifying dysfunctional crosstalk of pathways in various regions of Alzheimer's disease brains. BMC Syst Biol 2010, 4(Suppl 2):S11. 10.1186/1752-0509-4-S2-S11, 2982685, 20840725.
    • (2010) BMC Syst Biol , vol.4 , Issue.SUPPL. 2
    • Liu, Z.P.1    Wang, Y.2    Zhang, X.S.3    Chen, L.4


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