SKF 83566 attenuates the effects of ghrelin on performance in the object location memory task

Neuroscience Letters

Volumn 504, Issue 3, 2011, Pages 316-320

  Jacoby, Sarah M ^a   Currie, Paul J ^a  

^a REED COLLEGE   (United States)

Author keywords

D 1 receptor antagonist; Food intake; Ghrelin; Memory; Object location task; SKF 83566

Indexed keywords

8 BROMO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL; DOPAMINE 1 RECEPTOR; GHRELIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN THIRD VENTRICLE; CONTROLLED STUDY; FOOD INTAKE; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPATIAL MEMORY; TASK PERFORMANCE;

2,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-1-PHENYL-1H-3-BENZAZEPINE; ANIMALS; APPETITE; DOPAMINE; DOPAMINE ANTAGONISTS; EATING; EXPLORATORY BEHAVIOR; GHRELIN; INJECTIONS, INTRAVENTRICULAR; LONG-TERM POTENTIATION; MALE; MEMORY DISORDERS; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; SPATIAL BEHAVIOR;

EID: 82455188053     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.09.056     Document Type: Article

References (44)

1. Abel T., Lattal K.M. Molecular mechanisms of memory acquisition, consolidation and retrieval. Curr. Opin. Neurobiol. 2001, 11:180-187.
2. Abizaid A., Horvath T.L. Brain circuits regulating energy homeostasis. Regul. Pept. 2008, 149:3-10.
3. Aguilar-Valles A., Sanchez E., deGortari P., Ramirez-Amaya V., Bermudez-Rattoni F., Joseph-Bravo P. Analysis of the stress response in rats trained in the water-maze: differential expression of corticotropin-releasing hormone, CRH-R1, glucocorticoid receptors and brain-derived neurotrophic factor in limbic regions. Neuroendocrinology 2005, 82(5-6):306-319.
4. Andrews Z.B., Erion D., Beiler R., Liu Z.W., Abizaid A., Zigman J., Elsworth J.D., Savitt J.M., DiMarchi R., Tschoep M., Roth R.H., Gao X.B., Horvath T.L. Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism. J. Neurosci. 2009, 29:14057-14065.
5. Atcha Z., Chen W.S., Ong A.B., Wong F.K., Neo A., Browne E.R., Witherington J., Pemberton D.J. Cognitive enhancing effects of ghrelin receptor agonists. Psychopharmacology 2009, 206:415-427.
6. Carlini V.P., Monzon M.E., Varas M.M., Cragnolini A.B., Schioth H.B., Scimonelli T.N., de Barioglio S.R. Ghrelin increases anxiety-like behavior and memory retention in rats. Biochem. Biophys. Res. Commun. 2002, 299(5):739-743.
7. Carlini V.P., Varas M.M., Cragnolini A.B., Schioth H.B., Scimonelli T.N., de Barioglio S.R. Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin. Biochem. Biophys. Res. Commun. 2004, 313(3):635-641.
8. Carlini V.P., Martini A.C., Schioth H.B., Ruiz R.D., Fiol de Cuneo M., de Barioglio S.R. Decreased memory for novel object recognition in chronically food-restricted mice is reversed by acute ghrelin administration. Neuroscience 2008, 153:929-934.
9. Carlini V.P., Ghersi M., Schioth H.B., de Barioglio S.R. Ghrelin and memory: differential effects on acquisition and retrieval. Peptides 2010, 31:1190-1193.
10. Carlini V.P., Perez M.F., Salde E., Schioth H.B., Ramirez O.A., de Barioglio S.R. Ghrelin induced memory facilitation implicates nitric oxide synthase activation and decrease in the threshold to promote LTP in hippocampal dentate gyrus. Physiol. Behav. 2010, 101:117-123.
11. Carvajal P., Carlini V.P., Shioth H.B., de Barioglio S.R., Salvatierra N.A. Central ghrelin increases anxiety in the open field test and impairs retention memory in a passive avoidance task in neonatal chicks. Neurobiol. Learn Mem. 2009, 91:402-407.
12. Cowley M.A., Smith R.G., Diano S., Tschöp M., Pronchuk N., Grove K.L., Strasburger C.J., Bidlingmaier M., Esterman M., Heiman M.L., Garcia-Segura L.M., Nillni E.A., Mendez P., Low M.J., Sotonyi P., Friedman J.M., Liu H., Pinto S., Colmers W.F., Cone R.D., Horvath T.L. The distribution of and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron 2003, 37:649-661.
13. Currie P.J., Coiro C.D., Duenas R., Guss J.L., Mirza A., Tal N. Urocortin I inhibits the effects of ghrelin and neuropeptide Y on feeding and energy substrate utilization. Brain Res. 2011, 1385:127-134.
14. Currie P.J., John C.S., Nicholson M.L., Chapman C.D., Loera K.E. Hypothalamic paraventricular 5-hydroxytryptamine inhibits the effects of ghrelin on eating and energy substrate utilization. Pharmacol. Biochem. Behav. 2010, 97(1):152-155.
15. Currie P.J., Mirza A., Fuld R., Park D., Vasselli J.R. Ghrelin is an orexigenic and metabolic signaling peptide in the arcuate and paraventricular nuclei. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2005, 289(2):R353-R358.
16. Dere E., Huston J.P., de Souza Silva M.A. The pharmacology, neuroanatomy, and neurogenetics of one-trial object recognition in rodents. Neurosci. Biobehav. Rev. 2007, 31:673-704.
17. Diano S., Farr A.S., Benoit S.C., McNay E.C., da Silva I., Horvath B. Ghrelin controls hippocampal spine synapse density and memory performance. Nat. Neurosci. 2006, 9:381-388.
18. Dix S.L., Aggleton J.P. Extending the spontaneous preference test of recognition: evidence of object-location and object-context recognition. Behav. Brain Res. 1999, 99:191-200.
19. Ennaceur A., Neave N. Spontaneous object recognition and object location memory in rats: the effects of lesions in the cingulate cortices, the medial prefrontal cortex, the cingulum bundle and the fornix. Exp. Brain Res. 1997, 113:509-519.
20. Faulconbridge L.F., Cummings D.E., Kaplan J.M., Grill H.J. Hyperphagic effects of brainstem ghrerlin administration. Diabetes 2003, 52:2260-2265.
21. Gahete M.D., Córdoba-Chacón J., Salvatori R., Castaño J.P., Kineman R.D., Luque R.M. Metabolic regulation of ghrelin O-acyl transferase (GOAT) expression in the mouse hypothalamus, pituitary, and stomach. Mol. Cell. Endocrinol. 2010, 317:154-160.
22. Howard H.D., Feighner S.D., Cully D.F., Arena J.P., Liberator P.A., Rosenblum C.I., Hamelin M., Hreniuk D.L., Palyha O.C., Anderson J., Paress P.S., Diaz C., Chou M., Liu K.K., McKee K.K., Pong S.S., Chaung L.Y., Elbrecht A., Dashkevicz M., Heavens R., Rigby M., Sirinathsinghji D.J.S., Dean D.C., Melillo D.G., Patchett A.A., Nargund R., Griffith P.R., DeMartino J.A., Gupta S.K., Shaeffer J.M., Smith R.G., Van der Ploeg L.H.T. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 1996, 273:974-976.
23. 5 receptor agonists induce a protein synthesis-dependent late potentiation in the CA1 region of the hippocampus. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:2446-2450.
24. Jerlhag E., Egecioglu E., Dickson S.L., Douhan A., Svensson L., Engel J.A. Ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens. Addict. Biol. 2007, 12(1):6-16.
25. Jerlhag E., Egecioglu E., Landgren S., Salome N., Heilig M., Moechars D., Datta R., Perrissoud D., Dickson S.L., Engel J.A. Requirement of central ghrelin signaling for alcohol reward. Proc. Natl. Acad. Sci. U.S.A. 2009, 106(27):11318-11323.
26. Jerlhag E., Egecioglu E., Dickson S.L., Engel J.A. Ghrelin receptor antagonism attenuates cocaine- and amphetamine-induced locomotor stimulation, accumbal dopamine release, and conditioned place preference. Psychopharmacology 2010, 211:415-422.
27. Jiang H., Betancourt L., Smith R.G. Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor/dopamine receptor subtype 1 heterodimers. Mol. Endocrinol. 2006, 20:1772-1785.
28. Lisman J.E., Grace A.A. The hippocampal-VTA loop: controlling the entry of information into long-term memory. Neuron 2005, 46:703-713.
29. O'Carroll C.M., Martin S.J., Sandin J., Frenguelli B., Morris R.G.M. Dopaminergic modulation of the persistence of one-trial hippocampus-dependent memory. Learn Mem. 2006, 13:760-769.
30. Olzsewski P.K., Grace M.K., Billington C.J., Levine A.S. Hypothalamic paraventricular injections of ghrelin: effect on feeding and c-Fos immunoreactivity. Peptides 2003, 24:919-923.
31. 5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippocampal synapses. J. Neurosci. 1996, 16:7478-7486.
32. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates 2007, Academic Press, New York.
33. Puighermanal E., Marsicano G., Busquets-Garcia A., Lutz B., Maldonado R., Ozaita A. Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling. Nat. Neurosci. 2009, 12:1152-1158.
34. Quinlan M.G., Hussain D., Brake W.G. Use of cognitive strategies in rats: the role of estradiol and its interaction with dopamine. Horm. Behav. 2007, 53:185-191.
35. 5 receptors facilitates the induction of presynaptic long-term potentiation at hippocampal output synapses. Eur. J. Neurosci. 2010, 32:598-605.
36. Seamans J.K., Floresco S.B., Phillips A.G. D-1 receptor modulation of hippocampal-prefrontal cortical circuits integrating spatial memory with executive functions in rat. J. Neurosci. 1998, 18:1613-1621.
37. Shuto Y., Shibasaki T., Otagiri A., Kuriyama H., Ohata H., Tamara H., Kamegai J., Sugihara H., Oikawa S., Wakabayashi I. Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding and adiposity. J. Clin. Invest. 2002, 109:1429-1436.
38. Shuto Y., Shibasaki T., Wada K., Parhar I., Kamegai J., Sugihara H., Oikawa S., Wakabayashi I. Generation of polyclonal antiserum against the growth hormone secretagogue receptor (GHS-R). Evidence the GHS-R exists in the hypothalamus, pituitary and stomach of rats. Life Sci. 2001, 68:991-996.
39. Smith R.G., Leonard R., Bailey A.R., Palyha O., Feighner S., Tan C., McKee K.K., Pong S.S., Griffin P., Howard A. Growth hormone secretagogue receptor family members and ligands. Endocrine 2001, 14:9-14.
40. Toth K., Laszlo K., Lenard L. Role of intraamygdaloid acylated-ghrelin in spatial learning. Brain Res. Bull. 2010, 81:33-37.
41. Wang S.H., Morris R.G.M. Hippocampal-neocortical interactions in memory formation, consolidation and reconsolidation. Annu. Rev. Psychol. 2010, 61:49-79.
42. Weinberg Z.Y., Nicholson M.J., Currie P.J. 6-Hydroxydopamine lesions of the ventral tegmental area suppress ghrelin's ability to elicit food-reinforced behavior. Neurosci. Lett. 2011, 499:70-73.
43. Wren A.M., Small C.J., Ward H.L., Murphy K.G., Dakin C.L., Taher S., Kennedy A.R., Roberts G.H., Morgan D.G., Ghatei M.A., Bloom S.R. The novel hypothalamic peptide ghrelin stimulates food intake and GH secretion. Endocrinology 2000, 141:4325-4328.
44. Zigman J.M., Jones J.E., Lee C.E., Saper C.B., Elmquist J.K. Expression of ghrelin receptor mRNA in the rat and the mouse brain. J. Comp. Neurol. 2006, 494:528-548.