The recombinant gut-associated M17 leucine aminopeptidase in combination with different adjuvants confers a high level of protection against Fasciola hepatica infection in sheep

Vaccine

Volumn 29, Issue 48, 2011, Pages 9057-9063

  Maggioli, Gabriela ^a   Acosta, Daniel ^a   Silveira, Fernando ^a   Rossi, Silvina ^b   Giacaman, Sheila ^a   Basika, Tatiana ^a   Gayo, Valeria ^c   Rosadilla, Diego ^c   Roche, Leda ^d   Tort, José ^d   Carmona, Carlos ^a  

^a Universidad de la Republica Instituto de Higiene   (Uruguay)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^c DILAVE   (Uruguay)

^d DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

Author keywords

Fasciola hepatica; Leucine aminopeptidase; Ruminants; Vaccine

Indexed keywords

ADJUVANT; ALUMINUM HYDROXIDE; ALUMINUM POTASSIUM SULFATE; DIETHYLAMINOETHYLDEXTRAN; FASCIOLA HEPATICA VACCINE; FREUND ADJUVANT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; METALLOPROTEINASE; RECOMBINANT ENZYME; RECOMBINANT M17 LEUCINE AMINOPEPTIDASE; UNCLASSIFIED DRUG; VACCINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ESCHERICHIA COLI; FASCIOLA HEPATICA; FASCIOLIASIS; GROUPS BY AGE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOASSAY; INOCULATION; INTESTINE; LIVER; MALE; METACERCARIA; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; SHEEP; TREATMENT DURATION; TREMATODE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, HELMINTH; ANTIBODY FORMATION; FASCIOLA HEPATICA; FASCIOLIASIS; IMMUNOGLOBULIN G; LEUCYL AMINOPEPTIDASE; MALE; PARASITE LOAD; RECOMBINANT PROTEINS; SHEEP; SHEEP DISEASES; SHEEP, DOMESTIC; VACCINATION; VACCINES;

EID: 82455171862     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2011.09.020     Document Type: Article

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