Effects of rs6234/rs6235 and rs6232/rs6234/rs6235 PCSK1 single-nucleotide polymorphism clusters on proprotein convertase 1/3 biosynthesis and activity

Molecular Genetics and Metabolism

Volumn 104, Issue 4, 2011, Pages 682-687

  Mbikay, Majambu ^a,b,c   Sirois, Francine ^a   Nkongolo, Kabwe K ^d   Basak, Ajoy ^a,b,c   Chrétien, Michel ^a,b,c  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

^d LAURENTIAN UNIVERSITY   (Canada)

Author keywords

Allelic cluster; PC1 3; PCSK1; Proopiomelanocortin; Proprotein convertase 1; Single nucleotide polymorphism

Indexed keywords

PROOPIOMELANOCORTIN; PROPROTEIN CONVERTASE 1;

ALLELE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SYNTHESIS; GENE EXPRESSION; GENETIC VARIABILITY; IMMUNOBLOTTING; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; RAT; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; ANIMALS; GENE EXPRESSION; ISOENZYMES; MODELS, MOLECULAR; POLYMORPHISM, SINGLE NUCLEOTIDE; PRO-OPIOMELANOCORTIN; PROPROTEIN CONVERTASE 1; RATS; RECOMBINANT PROTEINS;

RATTUS;

EID: 82355191718     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2011.09.027     Document Type: Article

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