The C-terminal region of the proprotein convertase 1/3 (PC1/3) exerts a bimodal regulation of the enzyme activity in vitro

FEBS Journal

Volumn 274, Issue 13, 2007, Pages 3482-3491

  Rabah, Nadia ^a   Gauthier, Dany ^a   Dikeakos, Jimmy D ^a   Reudelhuber, Timothy L ^a   Lazure, Claude ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

C terminal domain; Convertase; Prohormone; Regulation; Subtilisin

Indexed keywords

ENZYME PRECURSOR; FURIN; PROPROTEIN CONVERTASE 1; PROTEINASE; SUBTILISIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONCENTRATION RESPONSE; ENZYME ACTIVITY; ENZYME SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PURIFICATION;

ANIMALS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FURIN; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INSECTS; KINETICS; MICE; PEPTIDES; PROPROTEIN CONVERTASE 1; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 34347380731     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.05883.x     Document Type: Article

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