Conjugation of hydroxyapatite nanocrystals with human immunoglobulin G for nanomedical applications

Colloids and Surfaces B: Biointerfaces

Volumn 90, Issue 1, 2012, Pages 1-7

  Iafisco, Michele ^a,b   Varoni, Elena ^a   Di Foggia, Michele ^b   Pietronave, Stefano ^a,e   Fini, Milena ^c   Roveri, Norberto ^b   Rimondini, Lia ^a,d   Prat, Maria ^a,d  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^d Biotecnologie per la Ricerca Medica Applicata (BRMA)   (Italy)

^e WASEDA UNIVERSITY   (Japan)

Author keywords

Antibody; Functionalization; Hydroxyapatite; Nanocrystals; Nanomedicine

Indexed keywords

ADSORPTION CAPABILITY; DOSE-DEPENDENT; DRUG CARRIER; FREUNDLICH; FUNCTIONALIZATION; FUNCTIONALIZED; HUMAN IMMUNOGLOBULIN; HYDROXYAPATITE NANOCRYSTALS; IMMUNOCHEMICAL TECHNIQUES; LANGMUIRS; MAXIMUM LOADING; NANO-SIZED; NANOMEDICINES; PREFERENTIAL ORIENTATION; SECONDARY STRUCTURES; SELECTIVE RECOGNITION; STERIC HINDRANCES; TARGETED DRUG DELIVERY; THEORETICAL MODELS; WESTERN BLOTS;

ADSORPTION; APATITE; BINDING SITES; BIOMIMETICS; DRUG DELIVERY; HYDROXYAPATITE; MEDICAL NANOTECHNOLOGY; NANOCRYSTALS; NANOPARTICLES;

ANTIBODIES;

CARBONIC ACID; HYDROXYAPATITE; IMMUNOGLOBULIN G; NANOCRYSTAL; NANOPARTICLE;

ADSORPTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CONJUGATION; DRUG DELIVERY SYSTEM; PARTICLE SIZE; POWDER; PRIORITY JOURNAL; STEREOSPECIFICITY; THEORETICAL MODEL;

ADSORPTION; ANTINEOPLASTIC AGENTS; BINDING SITES; BLOTTING, WESTERN; DRUG CARRIERS; DURAPATITE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOCONJUGATES; IMMUNOGLOBULIN G; MOLECULAR TARGETED THERAPY; NANOMEDICINE; NANOPARTICLES; NEOPLASMS; PARTICLE SIZE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SPECTRUM ANALYSIS; STATIC ELECTRICITY; SURFACE PROPERTIES;

EID: 82355190222     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2011.09.033     Document Type: Article

References (37)

1. Pietronave S., Iafisco M., Locarno D., Rimondini L., Maria Prat M. Functionalized nanomaterials for diagnosis and therapy of cancer. J. Appl. Biomater. Biomech. 2009, 7:77-89.
2. Peer D., Karp J.M., Hong S., FaroKHzad O.C., Margalit R., Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat. Nanotechnol. 2007, 2:751-760.
3. Davis M.E., Chen Z., Shin D.M. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat. Rev. Drug Discov. 2008, 7:771-782.
4. Cho K.J., Wang X., Nie S.M., Chen Z., Shin D.M. Therapeutic nanoparticles for drug delivery in cancer. Clin. Cancer Res. 2008, 14:1310-1316.
5. Iafisco M., Palazzo B., Falini G., Foggia M.D., Bonora S., Nicolis S., Casella L., Roveri N. Adsorption and conformational change of myoglobin on biomimetic hydroxyapatite nanocrystals functionalized with alendronate. Langmuir 2008, 24:4924-4930.
6. Leucuta S.E. Nanotechnology for delivery of drugs and biomedical applications. Curr. Clin. Pharmacol. 2010, 5:257-280.
7. Roveri N., Palazzo B., Iafisco M. The role of biomimetism in developing nanostructured inorganic matrices for drug delivery. Expert Opin. Drug Deliv. 2008, 5:861-877.
8. Roveri N., Palazzo B. Hydroxyapatite Nanocrystals as Bone Tissue Substitute 2007, Wiley-VCH Verlag GmbH & Co. KGaA.
9. Epple M., Ganesan K., Heumann R., Klesing J., Kovtun A., Neumann S., Sokolova V. Application of calcium phosphate nanoparticles in biomedicine. J. Mater. Chem. 2010, 20:18-23.
10. Uskokovic V., Uskokovic D.P. Nanosized hydroxyapatite and other calcium phosphates: chemistry of formation and application as drug and gene delivery agents. J. Biomed. Mater. Res. B: Appl. Biomater. 2011, 96:152-191.
11. Petros R.A., DeSimone J.M. Strategies in the design of nanoparticles for therapeutic applications. Nat. Rev. Drug Discov. 2010, 9:615-627.
12. Adams G.P., Weiner L.M. Monoclonal antibody therapy of cancer. Nat. Biotechnol. 2005, 23:1147-1157.
13. Platt V.M., Szoka F.C. Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor. Mol. Pharm. 2008, 5:474-486.
14. Zafir-Lavie I., Michaeli Y., Reiter Y. Novel antibodies as anticancer agents. Oncogene 2007, 26:3714-3733.
15. Prat M., Narsimhan R.P., Crepaldi T., Nicotra M.R., Natali P.G., Comoglio P.M. The receptor encoded by the human c-Met oncogene is expressed in hepatocytes, epithelial-cells and solid tumors. Int. J. Cancer 1991, 49:323-328.
16. Tseng C.L., Wang T.W., Dong G.C., Wu S.Y.H., Young T.H., Shieh M.J., Lou P.J., Lin F.H. Development of gelatin nanoparticles with biotinylated EGF conjugation for lung cancer targeting. Biomaterials 2007, 28:3996-4005.
17. Chen H.W., Gao J., Lu Y., Kou G., Zhang H., Fan L., Sun Z.G., Guo Y.J., Zhong Y.Q. Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy. J. Control. Release 2008, 128:209-216.
18. Mamot C., Drummond D.C., Noble C.O., Kallab V., Guo Z., Hong K., Kirpotin D.B., Park J.W. Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo. Cancer Res. 2005, 65:11631-11638.
19. Gullotti E., Yeo Y. Extracellularly activated nanocarriers: a new paradigm of tumor targeted drug delivery. Mol. Pharm. 2009, 6:1041-1051.
20. Arruebo M., Valladares M., Gonzalez-Fernandez A. Antibody-conjugated nanoparticles for biomedical applications. J. Nanomater. 2009, -
21. Gagnon P. Monoclonal antibody purification with hydroxyapatite. New Biotechnol. 2009, 25:287-293.
22. Roque A.C.A., Bispo S., Pinheiro A.R.N., Antunes J.M.A., Goncalves D., Ferreira H.A. Antibody immobilization on magnetic particles. J. Mol. Recogn. 2009, 22:77-82.
23. Brunauer S., Emmett P.H., Teller E. Adsorption of gases in multimolecular layers. J. Am. Chem. Soc. 1938, 60:309-319.
24. Langmuir I. The adsorption of gases on plane surfaces of glass, mica and platinum. J. Am. Chem. Soc. 1918, 40:1361-1403.
25. Iafisco M., Di Foggia M., Bonora S., Prat M., Roveri N. Adsorption and spectroscopic characterization of lactoferrin on hydroxyapatite nanocrystals. Dalton Trans. 2011, 40:820-827.
26. Sips R. On the structure of a catalyst surface. J. Chem. Phys. 1948, 16:490-495.
27. Rill C., Kolar Z.I., Kickelbick G., Wolterbeek H.T., Peters J.A. Kinetics and thermodynamics of adsorption on hydroxyapatite of the [Tb-160]Terbium complexes of the bone-targeting ligands DOTP and BPPED. Langmuir 2009, 25:2294-2301.
28. Rey C., Combes C., Drouet C., Lebugle A., Sfihi H., Barroug A. Nanocrystalline apatites in biological systems: characterisation, structure and properties. Materialwissenschaft Werkst 2007, 38:996-1002.
29. Dorozhkin S.V. Nanosized and nanocrystalline calcium orthophosphates. Acta Biomater. 2010, 6:715-734.
30. Palazzo B., Iafisco M., Laforgia M., Margiotta N., Natile G., Bianchi C.L., Walsh D., Mann S., Roveri N. Biomimetic hydroxyapatite-drug nanocrystals as potential bone substitutes with antitumor drug delivery properties. Adv. Funct. Mater. 2007, 17:2180-2188.
31. Kandori K., Miyagawa K., Ishikawa T. Adsorption of immunogamma globulin onto various synthetic calcium hydroxyapatite particles. J. Colloid Interf. Sci. 2004, 273:406-413.
32. Iafisco M., Sabatino P., Lesci I.G., Prat M., Rimondini L., Roveri N. Conformational modifications of serum albumins adsorbed on different kinds of biomimetic hydroxyapatite nanocrystals. Colloids Surf. B Biointerf. 2010, 81:274-284.
33. Batalha I.L., Hussain A., Roque A.C.A. Gum Arabic coated magnetic nanoparticles with affinity ligands specific for antibodies. J. Mol. Recogn. 2010, 23:462-471.
34. Gorbunoff M.J., Timasheff S.N. The interaction of protein with hydroxyapatite: III. Mechanism. Anal. Biochem. 1984, 136:440-445.
35. Chen Y., Zhang X., Gong Y., Zhao N., Zeng T., Song X. Conformational changes of fibrogen adsorption onto hydroxyapatite and titanium oxide nanoparticles. J. Colloid Interf. Sci. 1999, 214:38-45.
36. 2 surfaces. J. Mol. Struct. 2009, 924-926:120-126.
37. Di Foggia M., Taddei P., Torreggiani A., Dettin M., Tinti A. Interactions between oligopeptides and oxidised titanium surfaces detected by vibrational spectroscopy. J. Raman Spectrosc. 2010, 42:276-285.