A multi-technique approach to the study of structural stability and desolvation of two unusual channel hydrate solvates of finasteride

Journal of Pharmaceutical Sciences

Volumn 101, Issue 1, 2012, Pages 176-186

  Byard, Stephen ^a   Abraham, Anuji ^b   T Boulton, Paul J ^b   Harris, Robin K ^b   Hodgkinson, Paul ^b  

^a Alnwick Research Centre   (United Kingdom)

^b DURHAM UNIVERSITY   (United Kingdom)

Author keywords

Desolvation; DVS; Finasteride; Hydrates solvates; Magic angle spinning; Solid state NMR; TGA MS; Thermal analysis; X ray powder diffraction

Indexed keywords

BISFINASTERIDE MONOHYDRATE MONO 1,4 DIOXANE; BISFINASTERIDE MONOHYDRATE MONOTETRAHYDROFURAN; DRUG SOLVENT; FINASTERIDE; UNCLASSIFIED DRUG; WATER;

ARTICLE; DRUG STABILITY; DRUG STRUCTURE; ENVIRONMENT; HYDROGEN BOND; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE IMAGING; SOLVATE; THERMAL ANALYSIS; THERMOGRAVIMETRY; WATER VAPOR; X RAY DIFFRACTION;

EID: 82255175815     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22740     Document Type: Article

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