Reliability evaluation of nonlinear design space in pharmaceutical product development

Journal of Pharmaceutical Sciences

Volumn 101, Issue 1, 2012, Pages 333-341

  Hayashi, Yoshihiro ^a   Kikuchi, Shingo ^a   Onuki, Yoshinori ^a   Takayama, Kozo ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Dissolution rate; Excipients; Formulation; Multivariate analysis; Nonlinear regression; Simulations; Solid dosage form; Stability

Indexed keywords

INDOMETACIN; LACTOSE; MICROCRYSTALLINE CELLULOSE; STARCH;

ARTICLE; CONFIDENCE INTERVAL; CORRELATION COEFFICIENT; DRUG DESIGN; DRUG FORMULATION; DRUG SCREENING; DRUG SOLUBILITY; EVALUATION; EXPERIMENTAL DESIGN; NONLINEAR SYSTEM; PRODUCT DEVELOPMENT; RELIABILITY; RESPONSE SURFACE METHOD; TABLET HARDNESS;

EID: 82255162804     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22734     Document Type: Article

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