Evaluation of the reliability of nonlinear optimal solutions in pharmaceuticals using a bootstrap resampling technique in combination with Kohonen's self-organizing maps

Journal of Pharmaceutical Sciences

Volumn 97, Issue 1, 2008, Pages 331-339

  Onuki, Yoshinori ^a   Ohyama, Koichi ^a   Kaseda, Chosei ^b   Arai, Hiroaki ^c   Suzuki, Tatsuya ^c   Takayama, Kozo ^a,b,c  

^a HOSHI UNIVERSITY   (Japan)

^b YAMATAKE CORPORATION   (Japan)

^c DAIICHI SANKYO CO   (Japan)

Author keywords

Dissolution rate; Multivariate analysis; Physical characterization; Preformulation; Processing; Simulations; Solid dosage form; Tableting

Indexed keywords

CEOLUS; LACTOSE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; STARCH; THEOPHYLLINE; UNCLASSIFIED DRUG;

ARTICLE; BOOTSTRAPPING; DRUG DOSAGE FORM; DRUG RELEASE; RELIABILITY; RESPONSE SURFACE METHOD; TABLET FORMULATION; TABLET HARDNESS;

EID: 38349141055     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21097     Document Type: Article

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