Complex estrogenic regulation of catechol-O-methyltransferase (COMT) in rats

Journal of Physiology and Pharmacology

Volumn 62, Issue 4, 2011, Pages 483-490

  Schendzielorz, Nadia ^a   Rysa, A ^a   Reenila, I ^a   Raasmaja, A ^a   Mannisto, P T ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Catechol O methyltransferase; Dopamine; Estrogen; Hormones; Ovariectomy; Prefrontal cortex; Rodents; Tamoxifen

Indexed keywords

CATECHOL METHYLTRANSFERASE; ESTRADIOL; TAMOXIFEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; IN VIVO STUDY; KIDNEY; MALE; NONHUMAN; OVARIECTOMY; PREFRONTAL CORTEX; PROSTATE; PROTEIN EXPRESSION; RAT; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; CATECHOL O-METHYLTRANSFERASE; DOWN-REGULATION; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGENS; FEMALE; KIDNEY; MALE; OVARIECTOMY; PREFRONTAL CORTEX; PROSTATE; RATS; RATS, WISTAR; TAMOXIFEN; UP-REGULATION;

EID: 82155192116     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Mannisto PT, Kaakkola S. Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors. Pharmacol Rev 1999; 51(4): 593-628.
2. Karhunen T, Tilgmann C, Ulmanen I, Julkunen I, Panula P. Distribution of catechol-O-methyltransferase enzyme in rat tissues. J Histochem Cytochem 1994; 42(8): 1079-1090.
3. Overbye A, Seglen PO. Phosphorylated and nonphosphorylated forms of catechol O-methyltransferase in rat liver, brain and other tissues. Biochem J 2009; 417(2): 535-545.
4. Nissinen E, Tuominen R, Perhoniemi V, Kaakkola S. Catechol-O-methyltransferase activity in human and rat small intestine. Life Sci 1988; 42(25): 2609-2614.
5. Karhunen T, Tilgmann C, Ulmanen I, Panula P. Catechol-Omethyltransferase (COMT) in rat brain: immunoelectron microscopic study with an antiserum against rat recombinant COMT protein. Neurosci Lett 1995; 187(1): 57-60.
6. Yavich L, Forsberg MM, Karayiorgou M, Gogos JA, Mannisto PT. Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum. J Neurosci 2007; 27(38): 10196-10209.
7. Guldberg HC, Marsden CA. Catechol-O-methyl transferase: pharmacological aspects and physiological role. Pharmacol Rev 1975; 27(2): 135-206.
8. Tunbridge EM, Harrison PJ, Weinberger DR. Catechol-omethyltransferase, cognition, and psychosis: Val158Met and beyond. Biol Psychiatry 2006; 60(2): 141-151.
9. Cavalieri E, Chakravarti D, Guttenplan J, et al. Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention. Biochim Biophys Acta 2006; 1766(1): 63-78.
10. Cavalieri E, Rogan E. Catechol quinones of estrogens in the initiation of breast, prostate, and other human cancers: keynote lecture. Ann N Y Acad Sci 2006; 1089: 286-301.
11. Lundstrom K, Salminen M, Jalanko A, Savolainen R, Ulmanen I. Cloning and characterization of human placental catechol-O-methyltransferase cDNA. DNA Cell Biol 1991; 10(3): 181-189.
12. Salminen M, Lundstrom K, Tilgmann C, Savolainen R, Kalkkinen N, Ulmanen I. Molecular cloning and characterization of rat liver catechol-O-methyltransferase. Gene 1990; 93(2): 241-247.
13. Tenhunen J, Salminen M, Lundstrom K, Kiviluoto T, Savolainen R, Ulmanen I. Genomic organization of the human catechol O-methyltransferase gene and its expression from two distinct promoters. Eur J Biochem 1994; 223(3): 1049-1059.
14. Vieira-Coelho MA, Soares-da-Silva P. Ontogenic aspects of liver and kidney catechol-O-methyltransferase sensitivity to tolcapone. Br J Pharmacol 1996; 117(3): 516-520.
15. Cohn CK, Axelrod J. The effect of estradiol on catechol-Omethyltransferase activity in rat liver. Life Sci I 1971; 10(23): 1351-1354.
16. Parvez S, Parvez SH, Youdim MB. Variation in activity of monoamine metabolizing enzymes in rat liver during pregnancy. Br J Pharmacol 1975; 53(2): 241-246.
17. Parvez H, Parvez S, Raza-Bukhari A. Decreased phenylethanolamine-N-methyltransferase and catechol-Omethyltransferase activity in rabbit adrenal glands during pregnancy. Br J Pharmacol 1976; 57(3): 413-416.
18. Weisz J, Fritz-Wolz G, Clawson GA, Benedict CM, Abendroth C, Creveling CR. Induction of nuclear catechol-O-methyltransferase by estrogens in hamster kidney: implications for estrogen-induced renal cancer. Carcinogenesis 1998; 19(7): 1307-1312.
19. Boudikova B, Szumlanski C, Maidak B, Weinshilboum R. Human liver catechol-O-methyltransferase pharmacogenetics. Clin Pharmacol Ther 1990; 48(4): 381-389.
20. Fahndrich E, Coper H, Christ W, Helmchen H, Muller-Oerlinghausen B, Pietzcker A. Erythrocyte COMT-activity in patients with affective disorders. Acta Psychiatr Scand 1980; 61(5): 427-437.
21. Floderus Y, Ross SB, Wetterberg L. Erythrocyte catechol-Omethyltransferase activity in a Swedish population. Clin Genet 1981; 19(5): 389-392.
22. Xie T, Ho SL, Ramsden D. Characterization and implications of estrogenic down-regulation of human catechol-O-methyltransferase gene transcription. Mol Pharmacol 1999; 56(1): 31-38.
23. Jiang H, Xie T, Ramsden DB, Ho SL. Human catechol-Omethyltransferase down-regulation by estradiol. Neuropharmacology 2003; 45(7): 1011-1018.
24. Meyers B, D'Agostino A, Walker J, Kritzer MF. Gonadectomy and hormone replacement exert region-and enzyme isoform-specific effects on monoamine oxidase and catechol-O-methyltransferase activity in prefrontal cortex and neostriatum of adult male rats. Neuroscience 2010; 165(3): 850-862.
25. Hill RA, McInnes KJ, Gong EC, Jones ME, Simpson ER, Boon WC. Estrogen deficient male mice develop compulsive behavior. Biol Psychiatry 2007; 61(3): 359-366.
26. McDonnell DP, Connor CE, Wijayaratne A, Chang CY, Norris JD. Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators. Recent Prog Horm Res 2002; 57: 295-316.
27. McDonnell DP, Wijayaratne A, Chang CY, Norris JD. Elucidation of the molecular mechanism of action of selective estrogen receptor modulators. Am J Cardiol 2002; 90(1A): 35F-43F.
28. Kaenmaki M, Tammimaki A, Garcia-Horsman JA, et al. Importance of membrane-bound catechol-O-methyltransferase in L-DOPA metabolism: a pharmacokinetic study in two types of COMT gene modified mice. Br J Pharmacol 2009; 158(8): 1884-1894.
29. Karoum F, Chrapusta SJ, Egan MF. 3-Methoxytyramine is the major metabolite of released dopamine in the rat frontal cortex: reassessment of the effects of antipsychotics on the dynamics of dopamine release and metabolism in the frontal cortex, nucleus accumbens, and striatum by a simple two pool model. J Neurochem 1994; 63(3): 972-979.
30. Tunbridge EM, Bannerman DM, Sharp T, Harrison PJ. Catechol-o-methyltransferase inhibition improves setshifting performance and elevates stimulated dopamine release in the rat prefrontal cortex. J Neurosci 2004; 24(23): 5331-5335.
31. Aydin M, Yilmaz B, Alcin E, Nedzvetsky VS, Sahin Z, Tuzcu M. Effects of letrozole on hippocampal and cortical catecholaminergic neurotransmitter levels, neural cell adhesion molecule expression and spatial learning and memory in female rats. Neuroscience 2008; 151(1): 186-194.
32. Bershtein LM, Larionov AA, Kriukova OG, Kochnev VA, Semiglazov VF. Aromatase activity in human muscle tissue. Vopr Med Khim 1996; 42(1): 76-82.
33. Longcope C, Billiar RB, Takaoka Y, Reddy PS, Richardson D, Little B. Tissue sites of aromatization in the female rhesus monkey. Endocrinology 1983; 113(5): 1679-1682.
34. Matsumine H, Hirato K, Yanaihara T, Tamada T, Yoshida M. Aromatization by skeletal muscle. J Clin Endocrinol Metab 1986; 63(3): 717-720.
35. Zhao H, Tian Z, Hao J, Chen B. Extragonadal aromatization increases with time after ovariectomy in rats. Reprod Biol Endocrinol 2005; 3: 6.
36. Franczak A, Zmijewska A, Kurowicka B, Wojciechowicz B, Kotwica G. Interleukin 1beta-induced synthesis and secretion of prostaglandin E in the porcine uterus during various periods of pregnancy and the estrous cycle. J Physiol Pharmacol 2010; 61(6): 733-742.
37. Jose PA, Raymond JR, Bates MD, Aperia A, Felder RA, Carey RM. The renal dopamine receptors. J Am Soc Nephrol 1992; 2(8): 1265-1278.
38. +-ATPase activity in rat proximal convoluted tubule segments. Am J Physiol 1987; 252(1 Pt 2): F39-F45.
39. + intake on dopamineinduced inhibition of renal cortical Na(+)-K(+)-ATPase. Am J Physiol 1990; 258(1 Pt 2): F52-F60.
40. Felder CC, Campbell T, Albrecht F, Jose PA. Dopamine inhibits Na(+)-H+ exchanger activity in renal BBMV by stimulation of adenylate cyclase. Am J Physiol 1990; 259(2 Pt 2): F297-303.
41. Odlind C, Goransson V, Reenila I, Hansell P. Regulation of dopamine-induced natriuresisby the dopamine-metabolizing enzyme catechol-O-methyltransferase. Exp Nephrol 1999; 7(4): 314-322.
42. Odlind C, Reenila I, Mannisto PT, et al. Reduced natriuretic response to acute sodium loading in COMT gene deleted mice. BMC Physiol 2002; 2: 14.
43. Odlind C, Reenila I, Mannisto PT, Ekblom J, Hansell P. The role of dopamine-metabolizing enzymes in the regulation of renal sodium excretion in the rat. Pflugers Arch 2001; 442(4): 505-510.
44. Beland FA, McDaniel LP, Marques MM. Comparison of the DNAadducts formed by tamoxifen and 4-hydroxytamoxifen in vivo. Carcinogenesis 1999; 20(3): 471-477.
45. Carthew P, Edwards RE, Nolan BM, Martin EA, Smith LL. Tamoxifen associated uterine pathology in rodents: relevance to women. Carcinogenesis 1996; 17(8): 1577-1582.
46. Ickenstein LM, Bandiera SM. Persistent suppression of hepatic CYP2A1 expression and serum triiodothyronine levels by tamoxifen in intact female rats: dose-response analysis and comparison with 4-hydroxytamoxifen, fulvestrant (ICI 182,780), and 17beta-estradiol-3-benzoate. J Pharmacol Exp Ther 2002; 302(2): 584-593.
47. Wakeling AE, Bowler J. Biology and mode of action of pure antioestrogens. J Steroid Biochem 1988; 30(1-6): 141-147.
48. Cavalieri EL, Devanesan P, Bosland MC, Badawi AF, Rogan EG. Catechol estrogen metabolites and conjugates in different regions of the prostate of Noble rats treated with 4-hydroxyestradiol: implications for estrogen-induced initiation of prostate cancer. Carcinogenesis 2002; 23(2): 329-333.
49. Shughrue PJ, Lane MV, Merchenthaler I. Comparative distribution of estrogen receptor-alpha and-beta mRNA in the rat central nervous system. J Comp Neurol 1997; 388(4): 507-525.
50. Laflamme N, Nappi RE, Drolet G, Labrie C, Rivest S. Expression and neuropeptidergic characterization of estrogen receptors (ERa and ERb) throughout the rat brain: anatomical evidence of distinct roles of each subtype. J Neurobiol 1998; 36(3): 357-378.
51. Shughrue PJ, Merchenthaler I. Distribution of estrogen receptor beta immunoreactivity in the rat central nervous system. J Comp Neurol 2001; 436(1): 64-81.
52. Pelletier G. Localization of androgen and estrogen receptors in rat and primate tissues. Histol Histopathol 2000; 15(4): 1261-1270.
53. Barkhem T, Carlsson B, Nilsson Y, Enmark E, Gustafsson J, Nilsson S. Differential response of estrogen receptor alpha and estrogen receptor beta to partial estrogen agonists/antagonists. Mol Pharmacol 1998; 54(1): 105-112.
54. Smith CL, O'Malley BW. Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev 2004; 25(1): 45-71.
55. Li Y, Birnbaumer L, Teng CT. Regulation of ERR gene expression by estrogen receptor agonists and antagonists in SKBR3 breast cancer cells: differential molecular mechanisms mediated by g protein-coupled receptor GPR30/GPER-1. Mol Endocrinol 2010; 24(5): 969-980.
56. Filice E, Recchia AG, Pellegrino D, Angelone T, Maggiolini M, Cerra MC. A new membrane G protein-coupled receptor (GPR30) is involved in the cardiac effects of 17beta-estradiol in the male rat. J Physiol Pharmacol 2009; 60(4): 3-10.
57. Gillies GE, McArthur S. Estrogen actions in the brain and the basis for differential action in men and women: a case for sexspecific medicines. Pharmacol Rev 2010; 62(2): 155-198.