Runx2 contributes to murine Col10a1 gene regulation through direct interaction with its cis-enhancer

Journal of Bone and Mineral Research

Volumn 26, Issue 12, 2011, Pages 2899-2910

  Li, Feifei ^a,b   Lu, Yaojuan ^a   Ding, Ming ^a   Napierala, Dobrawa ^c   Abbassi, Sam ^a   Chen, Yuqing ^d   Duan, Xiangyun ^e   Wang, Siying ^b   Lee, Brendan ^d   Zheng, Qiping ^a  

^a RUSH MEDICAL COLLEGE   (United States)

^b ANHUI MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e ILLINOIS MATHEMATICS AND SCIENCE ACADEMY   (United States)

Author keywords

cis enhancer; Col10a1; hypertrophic chondrocytes; Runx2; transgenic studies

Indexed keywords

BETA GALACTOSIDASE; CIS ACTING ELEMENT; COL10A1 PROTEIN; COLLAGEN TYPE 10; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BINDING SITE; CARTILAGE CELL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE CONTROL; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; UPREGULATION;

ANIMALS; BASE PAIRING; BASE SEQUENCE; BINDING SITES; COLLAGEN TYPE X; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DNA; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; GENES, REPORTER; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; TANDEM REPEAT SEQUENCES;

EID: 81855224896     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.504     Document Type: Article

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