메뉴 건너뛰기




Volumn 24, Issue 6, 2011, Pages 626-632

Medulloblastomas in adults: Prognostic factors and lessons from paediatrics

Author keywords

adult medulloblastomas; molecular factors; prognostic factors; treatment

Indexed keywords

BETA CATENIN; CISPLATIN; CYCLIN DEPENDENT KINASE 6; CYCLOPHOSPHAMIDE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ETOPOSIDE; NEUROTROPHIN 3 RECEPTOR; SONIC HEDGEHOG PROTEIN; WNT PROTEIN;

EID: 81855221751     PISSN: 13507540     EISSN: 14736551     Source Type: Journal    
DOI: 10.1097/WCO.0b013e32834cd4b1     Document Type: Review
Times cited : (21)

References (61)
  • 4
    • 0014619880 scopus 로고
    • An operative staging system and a megavoltage radiotherapeutic technic for cerebellar medulloblastomas
    • Chang CH, Housepian EM, Herbert C Jr. An operative staging system and a megavoltage radiotherapeutic technic for cerebellar medulloblastomas. Radiology 1969; 93:1351-1359.
    • (1969) Radiology , vol.93 , pp. 1351-1359
    • Chang, C.H.1    Housepian, E.M.2    Herbert Jr., C.3
  • 7
    • 0025365252 scopus 로고
    • Adjuvant chemotherapy for medulloblastoma: The first multi-centre control trial of the International Society of Paediatric Oncology (SIOP I)
    • Tait DM, Thornton-Jones H, Bloom HJ, et al. Adjuvant chemotherapy for medulloblastoma: the first multicentre control trial of the International Society of Paediatric Oncology (SIOP I). Eur J Cancer 1990; 26:464-469. (Pubitemid 20209976)
    • (1990) European Journal of Cancer , vol.26 , Issue.4 , pp. 464-469
    • Tait, D.M.1    Thornton-Jones, H.2    Bloom, H.J.G.3    Lemerle, J.4    Morris-Jones, P.5
  • 8
    • 0026024121 scopus 로고
    • Improved survival with the use of adjuvant chemotherapy in the treatment of medulloblastoma
    • Packer RJ, Sutton LN, Goldwein JW, et al. Improved survival with the use of adjuvant chemotherapy in the treatment of medulloblastoma. J Neurosurg 1991; 74:433-440.
    • (1991) J Neurosurg , vol.74 , pp. 433-440
    • Packer, R.J.1    Sutton, L.N.2    Goldwein, J.W.3
  • 11
    • 64049087816 scopus 로고    scopus 로고
    • Long-term outcome and clinical prognostic factors in children with medulloblastoma treated in the prospective randomised multicentre trial HIT'91
    • Von Hoff K, Hinkes B, Gerber NU, et al. Long-term outcome and clinical prognostic factors in children with medulloblastoma treated in the prospective randomised multicentre trial HIT'91. Eur J Cancer 2009; 45:1209-1217.
    • (2009) Eur J Cancer , vol.45 , pp. 1209-1217
    • Von Hoff, K.1    Hinkes, B.2    Gerber, N.U.3
  • 15
    • 0038309244 scopus 로고    scopus 로고
    • Medulloblastoma: Present concepts of stratification into risk groups
    • DOI 10.1159/000071316
    • Packer RJ, Rood BR, MacDonald TJ. Medulloblastoma: present concepts of stratification into risk groups. Pediatr Neurosurg 2003; 39:60-67. (Pubitemid 36829097)
    • (2003) Pediatric Neurosurgery , vol.39 , Issue.2 , pp. 60-67
    • Packer, R.J.1    Rood, B.R.2    MacDonald, T.J.3
  • 17
    • 64649086763 scopus 로고    scopus 로고
    • Online quality control, hyperfractionated radiotherapy alone and reduced boost volume for standard risk medulloblastoma: Long-term results of MSFOP 98
    • Carrie C, Grill J, Figarella-Branger D, et al. Online quality control, hyperfractionated radiotherapy alone and reduced boost volume for standard risk medulloblastoma: long-term results of MSFOP 98. J Clin Oncol 2009; 27: 1879-1883.
    • (2009) J Clin Oncol , vol.27 , pp. 1879-1883
    • Carrie, C.1    Grill, J.2    Figarella-Branger, D.3
  • 18
    • 6344282578 scopus 로고    scopus 로고
    • Current treatment of medulloblastoma: Recent advances and future challenges
    • DOI 10.1053/j.seminoncol.2004.07.009, PII S0093775404003318, Brain Tumors
    • Rood BR, Macdonald TJ, Packer RJ. Current treatment of medulloblastoma: recent advances and future challenges. Semin Oncol 2004; 31:666-675. (Pubitemid 39389018)
    • (2004) Seminars in Oncology , vol.31 , Issue.5 , pp. 666-675
    • Rood, B.R.1    MacDonald, T.J.2    Packer, R.J.3
  • 20
    • 41149088349 scopus 로고    scopus 로고
    • Survival of patients with adult medulloblastoma: A population-based study
    • DOI 10.1002/cncr.23329
    • Lai R. Survival of patients with adult medulloblastoma: a population-based study. Cancer 2008; 112:1568-1574. (Pubitemid 351441170)
    • (2008) Cancer , vol.112 , Issue.7 , pp. 1568-1574
    • Lai, R.1
  • 22
    • 70350520490 scopus 로고    scopus 로고
    • Survival and prognostic factors in a series of adults with medulloblastomas
    • Riffaud L, Saikali S, Leray E, et al. Survival and prognostic factors in a series of adults with medulloblastomas. J Neurosurg 2009; 111:478-487.
    • (2009) J Neurosurg , vol.111 , pp. 478-487
    • Riffaud, L.1    Saikali, S.2    Leray, E.3
  • 24
    • 0035407296 scopus 로고    scopus 로고
    • Survival and recurrence factors in adult medulloblastoma: The M.D. Anderson Cancer Center experience from 1978 to 1998
    • DOI 10.1215/S1522851700000582
    • Kunschner LJ, Kuttesch J, Hess K, Yung WK. Survival and recurrence factors in adult medulloblastoma: the M.D. Anderson Cancer Center experience from 1978 to 1998. Neuro Oncol 2001; 3:167-173. (Pubitemid 33674108)
    • (2001) Neuro-Oncology , vol.3 , Issue.3 , pp. 167-173
    • Kunschner, L.J.1    Kuttesch, J.2    Hess, K.3    Yung, W.K.A.4
  • 25
    • 37549007600 scopus 로고    scopus 로고
    • Adult medulloblastoma: Clinical profile and treatment results of 18 patients
    • DOI 10.1016/j.jocn.2007.06.007, PII S0967586807003724
    • Menon G, Krishnakumar K, Nair S. Adult medulloblastoma: clinical profile and treatment results of 18 patients. J Clin Neurosci 2008; 15:122-126. (Pubitemid 50012528)
    • (2008) Journal of Clinical Neuroscience , vol.15 , Issue.2 , pp. 122-126
    • Menon, G.1    Krishnakumar, K.2    Nair, S.3
  • 26
    • 52249104363 scopus 로고    scopus 로고
    • Characteristics and outcomes of medulloblastoma in adults
    • Ang C, Hauerstock D, Guiot MC, et al. Characteristics and outcomes of medulloblastoma in adults. Pediatr Blood Cancer 2008; 51:603-607.
    • (2008) Pediatr Blood Cancer , vol.51 , pp. 603-607
    • Ang, C.1    Hauerstock, D.2    Guiot, M.C.3
  • 27
    • 0034518223 scopus 로고    scopus 로고
    • Adult medulloblastoma: Prognostic factors and patterns of relapse
    • discussion, 631-622
    • Chan AW, Tarbell NJ, Black PM, et al. Adult medulloblastoma: prognostic factors and patterns of relapse. Neurosurgery 2000; 47:623-631; discussion 631-622.
    • (2000) Neurosurgery , vol.47 , pp. 623-631
    • Chan, A.W.1    Tarbell, N.J.2    Black, P.M.3
  • 28
    • 77955931907 scopus 로고    scopus 로고
    • Reappraisal of clinical outcome in adult medulloblastomas with emphasis on patterns of relapse
    • Chargari C, Feuvret L, Levy A, et al. Reappraisal of clinical outcome in adult medulloblastomas with emphasis on patterns of relapse. Br J Neurosurg 2010; 24:460-467.
    • (2010) Br J Neurosurg , vol.24 , pp. 460-467
    • Chargari, C.1    Feuvret, L.2    Levy, A.3
  • 33
    • 35648929959 scopus 로고    scopus 로고
    • Long-term results of a prospective study on the treatment of medulloblastoma in adults
    • DOI 10.1002/cncr.23003
    • Brandes AA, Franceschi E, Tosoni A, et al. Long-term results of a prospective study on the treatment of medulloblastoma in adults. Cancer 2007; 110:2035-2041. (Pubitemid 350036864)
    • (2007) Cancer , vol.110 , Issue.9 , pp. 2035-2041
    • Brandes, A.A.1    Franceschi, E.2    Tosoni, A.3    Blatt, V.4    Ermani, M.5
  • 34
    • 84873080526 scopus 로고    scopus 로고
    • Efficacy of tailored treatment for high-and low-risk medulloblastoma in adults: A large prospective phase II trial
    • 4-8 June 2010; Chicago IL.
    • Brandes AA, Franceschi E, Tosoni A, et al. Efficacy of tailored treatment for high-and low-risk medulloblastoma in adults: a large prospective phase II trial. In: Abstracts of American Society of Clinical Oncology Annual Meeting; 4-8 June 2010; Chicago, IL. 2010; 28:2003.
    • (2003) Abstracts of American Society of Clinical Oncology Annual Meeting , pp. 28
    • Brandes, A.A.1    Franceschi, E.2    Tosoni, A.3
  • 35
    • 67649408815 scopus 로고    scopus 로고
    • Adult neuroectodermal tumors of posterior fossa (medulloblastoma) and of supratentorial sites (stPNET)
    • Brandes AA, Franceschi E, Tosoni A, et al. Adult neuroectodermal tumors of posterior fossa (medulloblastoma) and of supratentorial sites (stPNET). Crit Rev Oncol Hematol 2009; 71:165-179.
    • (2009) Crit Rev Oncol Hematol , vol.71 , pp. 165-179
    • Brandes, A.A.1    Franceschi, E.2    Tosoni, A.3
  • 41
    • 0033843435 scopus 로고    scopus 로고
    • Neurotrophin receptor TrkC predicts good clinical outcome in medulloblastoma and other primitive neuroectodermal brain tumors
    • DOI 10.1055/s-2000-10044
    • Grotzer MA, Janss AJ, Phillips PC, Trojanowski JQ. Neurotrophin receptor TrkC predicts good clinical outcome in medulloblastoma and other primitive neuroectodermal brain tumors. Klin Padiatr 2000; 212:196-199. (Pubitemid 30650554)
    • (2000) Klinische Padiatrie , vol.212 , Issue.4 , pp. 196-199
    • Grotzer, M.A.1    Janss, A.J.2    Phillips, P.C.3    Trojanowski, J.Q.4
  • 44
    • 4143081483 scopus 로고    scopus 로고
    • Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients
    • DOI 10.1158/1078-0432.CCR-03-0721
    • Lamont JM, McManamy CS, Pearson AD, et al. Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients. Clin Cancer Res 2004; 10:5482-5493. (Pubitemid 39100486)
    • (2004) Clinical Cancer Research , vol.10 , Issue.16 , pp. 5482-5493
    • Lamont, J.M.1    McManamy, C.S.2    Pearson, A.D.3    Clifford, S.C.4    Ellison, D.W.5
  • 45
    • 70449134364 scopus 로고    scopus 로고
    • Histology and molecular pathology of pediatric brain tumors
    • Pfister S, Hartmann C, Korshunov A. Histology and molecular pathology of pediatric brain tumors. J Child Neurol 2009; 24:1375-1386.
    • (2009) J Child Neurol , vol.24 , pp. 1375-1386
    • Pfister, S.1    Hartmann, C.2    Korshunov, A.3
  • 46
    • 0033801873 scopus 로고    scopus 로고
    • C-MYC expression in medulloblastoma and its prognostic value
    • Herms J, Neidt I, Luscher B, et al. C-MYC expression in medulloblastoma and its prognostic value. Int J Cancer 2000; 89:395-402.
    • (2000) Int J Cancer , vol.89 , pp. 395-402
    • Herms, J.1    Neidt, I.2    Luscher, B.3
  • 48
    • 78049242921 scopus 로고    scopus 로고
    • Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma
    • Traenka C, Remke M, Korshunov A, et al. Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma. Cancer Res 2010; 70:8003-8014.
    • (2010) Cancer Res , vol.70 , pp. 8003-8014
    • Traenka, C.1    Remke, M.2    Korshunov, A.3
  • 49
    • 79954992066 scopus 로고    scopus 로고
    • Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables
    • Ellison DW, Kocak M, Dalton J, et al. Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables. J Clin Oncol 2011; 29:1400-1407.
    • (2011) J Clin Oncol , vol.29 , pp. 1400-1407
    • Ellison, D.W.1    Kocak, M.2    Dalton, J.3
  • 50
    • 79953321410 scopus 로고    scopus 로고
    • Rapid diagnosis of medulloblastoma molecular subgroups
    • Schwalbe EC, Lindsey JC, Straughton D, et al. Rapid diagnosis of medulloblastoma molecular subgroups. Clin Cancer Res 2011; 17: 1883-1894.
    • (2011) Clin Cancer Res , vol.17 , pp. 1883-1894
    • Schwalbe, E.C.1    Lindsey, J.C.2    Straughton, D.3
  • 52
    • 79954991010 scopus 로고    scopus 로고
    • Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
    • Cho YJ, Tsherniak A, Tamayo P, et al. Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. J Clin Oncol 2011; 29:1424-1430.
    • (2011) J Clin Oncol , vol.29 , pp. 1424-1430
    • Cho, Y.J.1    Tsherniak, A.2    Tamayo, P.3
  • 53
    • 79953146403 scopus 로고    scopus 로고
    • Predicting relapse in patients with medulloblastoma by integrating evidence from clinical and genomic features
    • Tamayo P, Cho YJ, Tsherniak A, et al. Predicting relapse in patients with medulloblastoma by integrating evidence from clinical and genomic features. J Clin Oncol 2011; 29:1415-1423.
    • (2011) J Clin Oncol , vol.29 , pp. 1415-1423
    • Tamayo, P.1    Cho, Y.J.2    Tsherniak, A.3
  • 54
    • 79955034739 scopus 로고    scopus 로고
    • Medulloblastoma comprises four distinct molecular variants
    • Northcott PA, Korshunov A, Witt H, et al. Medulloblastoma comprises four distinct molecular variants. J Clin Oncol 2011; 29:1408-1414.
    • (2011) J Clin Oncol , vol.29 , pp. 1408-1414
    • Northcott, P.A.1    Korshunov, A.2    Witt, H.3
  • 55
    • 52449119078 scopus 로고    scopus 로고
    • Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
    • Kool M, Koster J, Bunt J, et al. Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS One 2008; 3:e3088.
    • (2008) PLoS One , vol.3
    • Kool, M.1    Koster, J.2    Bunt, J.3
  • 56
    • 77954602395 scopus 로고    scopus 로고
    • Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification
    • Korshunov A, Remke M, Werft W, et al. Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification. J Clin Oncol 2010; 28:3054-3060.
    • (2010) J Clin Oncol , vol.28 , pp. 3054-3060
    • Korshunov, A.1    Remke, M.2    Werft, W.3
  • 57
    • 79960119129 scopus 로고    scopus 로고
    • Adult medulloblastoma comprises three major molecular variants
    • Remke M, Hielscher T, Northcott PA, et al. Adult medulloblastoma comprises three major molecular variants. J Clin Oncol 2011; 29:2717-2723.
    • (2011) J Clin Oncol , vol.29 , pp. 2717-2723
    • Remke, M.1    Hielscher, T.2    Northcott, P.A.3
  • 58
    • 78650811198 scopus 로고    scopus 로고
    • Subtypes of medulloblastoma have distinct developmental origins
    • Gibson P, Tong Y, Robinson G, et al. Subtypes of medulloblastoma have distinct developmental origins. Nature 2010; 468:1095-1099.
    • (2010) Nature , vol.468 , pp. 1095-1099
    • Gibson, P.1    Tong, Y.2    Robinson, G.3
  • 60
    • 79955010717 scopus 로고    scopus 로고
    • Hedgehogs, flies, Wnts and MYCs: The time has come for many things in medulloblastoma
    • Monje M, Beachy PA, Fisher PG. Hedgehogs, flies, Wnts and MYCs: the time has come for many things in medulloblastoma. J Clin Oncol 2011; 29:1395-1398.
    • (2011) J Clin Oncol , vol.29 , pp. 1395-1398
    • Monje, M.1    Beachy, P.A.2    Fisher, P.G.3
  • 61
    • 70349244812 scopus 로고    scopus 로고
    • Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449
    • Rudin CM, Hann CL, Laterra J, et al. Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449. N Engl J Med 2009; 361:1173-1178.
    • (2009) N Engl J Med , vol.361 , pp. 1173-1178
    • Rudin, C.M.1    Hann, C.L.2    Laterra, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.