Conversion of lipid transfer inhibitor protein (apolipoprotein F) to its active form depends on LDL composition

Journal of Lipid Research

Volumn 52, Issue 12, 2011, Pages 2262-2271

  Morton, Richard E ^a   Greene, Diane J ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Cholesteryl ester transfer protein; Lecithin:cholesterol acyltransferase; Lipid packing; Lipoprotein composition

Indexed keywords

APOLIPOPROTEIN F; CHOLESTEROL; CHOLESTEROL ESTER; CHOLESTEROL ESTER TRANSFER PROTEIN; INHIBITOR PROTEIN; LIPID TRANSFER INHIBITOR PROTEIN; LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; PHOSPHOLIPID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL COMPOSITION; CHEMICAL MODIFICATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; INCUBATION TEMPERATURE; LIPID COMPOSITION; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SYNTHESIS; PROTEIN TRANSPORT;

APOLIPOPROTEINS; CHOLESTEROL ESTER TRANSFER PROTEINS; HUMANS; LIPOPROTEINS, LDL; MOLECULAR WEIGHT; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; PROTEIN TRANSPORT;

EID: 81855217495     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M018283     Document Type: Article

References (39)

1. Morton, R. E. 1990. Interaction of lipid transfer protein with plasma lipoproteins and cell membranes. Experientia. 46: 552-560. (Pubitemid 20223812)
2. Tall, A. 1995. Plasma lipid transfer proteins. Annu. Rev. Biochem. 64: 235-257.
3. Morton, R. E., and J. V. Steinbrunner. 1990. Concentration of neutral lipids in the phospholipid surface of substrate particles determines lipid transfer protein activity. J. Lipid Res. 31: 1559-1567. (Pubitemid 20321717)
4. Morton, R. E., and A. P. Serdyuk. 1997. Cholesteryl ester transfer protein (CETP) has no preference for cholesteryl esters in high density- versus low density- lipoproteins. Circulation. 96: I-108.
5. Wang, X., D. M. Driscoll, and R. E. Morton. 1999. Molecular cloning and expression of lipid transfer inhibitor protein reveals its identity with apolipoprotein F. J. Biol. Chem. 274: 1814-1820.
6. Morton, R. E., and D. J. Greene. 1994. Regulation of lipid transfer between lipoproteins by an endogenous plasma protein: selective inhibition among lipoprotein classes. J. Lipid Res. 35: 836-847. (Pubitemid 24157235)
7. Morton, R. E. 1999. Cholesteryl ester transfer protein and its plasma regulator: lipid transfer inhibitor protein. Curr. Opin. Lipidol. 10: 321-327. (Pubitemid 29419689)
8. Lagor, W. R., R. J. Brown, S-A. Toh, J. S. Millar, I. V. Fuki, M. De la Llera-Moya, T. Yuen, G. Rothblat, J. T. Billheimer, and D. J. Rader. 2009. Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo. Arterioscler. Thromb. Vasc. Biol. 29: 40-46.
9. He, Y., D. J. Greene, M. Kinter, and R. E. Morton. 2008. Control of cholesteryl ester transfer protein activity by sequestration of lipid transfer inhibitor protein in an inactive complex. J. Lipid Res. 49: 1529-1537.
10. Stokke, K. T., and K. R. Norum. 1971. Determination of lecithin:cholesterol acyltransfer in human blood plasma. Scand. J. Clin. Lab. Invest. 27: 21-27.
11. Havel, R. J., H. A. Eder, and J. H. Bragdon. 1955. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Clin. Invest. 34: 1345-1353.
12. Morton, R. E., and D. B. Zilversmit. 1981. A plasma inhibitor of triglyceride and cholesteryl ester transfer activities. J. Biol. Chem. 256: 11992-11995. (Pubitemid 12139992)
13. Morton, R. E., and D. B. Zilversmit. 1982. Purification and characterization of lipid transfer protein(s) from human lipoproteindefi cient plasma. J. Lipid Res. 23: 1058-1067. (Pubitemid 13207271)
14. Pattnaik, N. M., A. Montes, L. B. Hughes, and D. B. Zilversmit. 1978. Cholesteryl ester exchange protein in human plasma: isolation and characterization. Biochim. Biophys. Acta. 530: 428-438. (Pubitemid 9016119)
15. Morton, R. E., and D. B. Zilversmit. 1981. The separation of apolipoprotein D from cholesteryl ester transfer protein. Biochim. Biophys. Acta. 663: 350-355. (Pubitemid 11169840)
16. Morton, R. E., H. M. Gnizak, D. J. Greene, K-H. Cho, and V. M. Paromov. 2008. Lipid transfer inhibitor protein (apolipoprotein F) concentration in normolipidemic and hyperlipidemic subjects. J. Lipid Res. 49: 127-135.
17. Peterson, G. L. 1977. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem. 83: 346-356. (Pubitemid 8269786)
18. Bartlett, G. R. 1959. Phosphorus assay in column chromatography. J. Biol. Chem. 234: 466-468.
19. Jauhiainen, M., and P. J. Dolphin. 1986. Human plasma lecithincholesterol acyltransferase: an elucidation of the catalytic mechanism. J. Biol. Chem. 261: 7032-7043. (Pubitemid 17219477)
20. Mann, C. J., F. T. Yen, A. M. Grant, and B. E. Bihain. 1991. Mechanism of plasma cholesteryl ester transfer in hypertriglyceridemia. J. Clin. Invest. 88: 2059-2066.
21. Murakami, T., S. Michelagnoli, R. Longhi, G. Gianfranceschi, F. Pazzucconi, L. Calabresi, C. R. Sirtori, and G. Franceschini. 1995. Triglycerides are major determinants of cholesterol esterification/transfer and HDL remodeling in human plasma. Arterioscler. Thromb. Vasc. Biol. 15: 1819-1828.
22. Morton, R. E. 1988. Interaction of plasma-derived lipid transfer protein with macrophages in culture. J. Lipid Res. 29: 1367-1377. (Pubitemid 18261059)
23. Morton, R. E., and D. B. Zilversmit. 1983. Inter-relationship of lipids transferred by the lipid-transfer protein isolated from human lipoprotein-deficient plasma. J. Biol. Chem. 258: 11751-11757. (Pubitemid 13019319)
24. Serdyuk, A. P., and R. E. Morton. 1999. Lipid transfer inhibitor protein defines the participation of lipoproteins in lipid transfer reactions: CETP has no preference for cholesteryl esters in HDL versus LDL. Arterioscler. Thromb. Vasc. Biol. 19: 718-726. (Pubitemid 29135177)
25. Tajima, S., S. Yokoyama, and A. Yamamoto. 1983. Effect of lipid particle size on association of apolipoproteins with lipid. J. Biol. Chem. 258: 10073-10082.
26. Ibdah, J. A., S. Lund-Katz, and M. C. Phillips. 1989. Molecular packing of high-density and low-density lipoprotein surface lipids and apolipoprotein A-I binding. Biochemistry. 28: 1126-1133.
27. Weinberg, R. B., J. A. Ibdah, and M. C. Phillips. 1992. Adsorption of apolipoprotein A-IV to phospholipid monolayers spread at the air/water interface. A model for its labile binding to high density lipoproteins. J. Biol. Chem. 267: 8977-8983.
28. Bisgaier, C. L., O. P. Sachdev, E. S. Lees, K. J. Williams, C. B. Blum, and R. M. Glickman. 1987. Effect of lecithin:cholesterol acyltransferase on distribution of apolipoprotein A-IV among lipoproteins of human plasma. J. Lipid Res. 28: 693-703. (Pubitemid 17085968)
29. Jiang, X. C., C. Bruce, T. Cocke, S. Wang, M. Boguski, and A. R. Tall. 1995. Point mutagenesis of positively charged amino acids of cholesteryl ester transfer protein: conserved residues within the lipid transfer/ lipopolysaccharide binding protein gene family essential for function. Biochemistry. 34: 7258-7263.
30. Qiu, X., A. Mistry, M. Ammirati, B. Chrunyk, R. Clark, Y. Cong, J. Culp, D. Danley, T. Freeman, K. Geoghegan, et al. 2007. Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules. Nat. Struct. Mol. Biol. 14: 106-113.
31. Morton, R. E. 1985. Binding of plasma-derived lipid transfer protein to lipoprotein substrates: the role of binding in the lipid transfer process. J. Biol. Chem. 260: 12593-12599. (Pubitemid 16233463)
32. Morton, R. E., and D. J. Greene. 2007. Partial suppression of CETP activity beneficially modifies the lipid transfer profile of plasma. Atherosclerosis. 192: 100-107. (Pubitemid 46628808)
33. Shen, B. W., A. M. Scanu, and F. J. Kézdy. 1977. Structure of human serum lipoproteins inferred from compositional analysis. Proc. Natl. Acad. Sci. USA. 74: 837-841. (Pubitemid 8068697)
34. Deckelbaum, R. J., S. Eisenberg, Y. Oschry, E. Butbul, I. Sharon, and T. Olivecrona. 1982. Reversible modification of human plasma low density lipoproteins toward triglyceride-rich particles: a mechanism for losing excess cholesterol esters. J. Biol. Chem. 257: 6509-6517. (Pubitemid 12059945)
35. Ben-Yashar, V., and Y. Barenholz. 1991. Characterization of the core and surface of human plasma lipoproteins. A study based on the use of five fluorophores. Chem. Phys. Lipids. 60: 1-14.
36. Massey, J. B., and H. J. Pownall. 1998. Surface properties of native hu man plasma lipoproteins and lipoprotein models. Biophys. J. 74: 869-878. (Pubitemid 28345280)
37. Krimbou, L., M. Marcil, J. Davignon, and J. Genest, Jr. 2001. Interaction of lecithin:cholesterol acyltransferase (LCAT) • alpha 2-macroglobulin complex with low density lipoprotein receptorrelated protein (LRP). Evidence for an alpha 2-macroglobulin/LRP receptor-mediated system participating in LCAT clearance. J. Biol. Chem. 276: 33241-33248.
38. Kärkkäinen, M., T. Oka, V. M. Olkkonen, J. Metso, H. Hattori, M. Jauhiainen, and C. Ehnholm. 2002. Isolation and partial characterization of the inactive and active forms of human plasma phospholipid transfer protein (PLTP). J. Biol. Chem. 277: 15413-15418. (Pubitemid 34967804)
39. Berneis, K. K., and R. M. Krauss. 2002. Metabolic origins and clinical significance of LDL heterogeneity. J. Lipid Res. 43: 1363-1379.