Effects of baicalin against oxidative stress injury of SH-SY5Y cells by up-regulating SIRT1

Yaoxue Xuebao

Volumn 46, Issue 9, 2011, Pages 1039-1044

  Chen, Hong Yan ^a   Geng, Miao ^a   Hu, Ya Zhuo ^a   Wang, Jian Hua ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Apoptosis; Baicalin; H2O2; SH SY5Y cell; SIRT1

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BAICALIN; CASPASE 3; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; NITRIC OXIDE; SIRTUIN 1;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL COUNT; CELL LEVEL; CELL VIABILITY; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; NERVE CELL LESION; OXIDATIVE STRESS; PROTEIN CONTENT; UPREGULATION;

ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; FLAVONOIDS; HUMANS; HYDROGEN PEROXIDE; L-LACTATE DEHYDROGENASE; NEUROBLASTOMA; NITRIC OXIDE; OXIDATIVE STRESS; PLANTS, MEDICINAL; SCUTELLARIA; SIRTUIN 1; UP-REGULATION;

EID: 81855200217     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Ye J, Zhai HZ. Oxidative stress and Alzheimer disease [J]. Chin J Clin Rehabil, 2005, 9: 117-119. (Pubitemid 43158501)
2. Smith MA, Hirai K, Hsiao K, et al. Amyloid-beta deposition in Alzheimer's transgenic mice is associated with oxidative stress [J]. Neurochemistry, 1998, 70: 2212-2215. (Pubitemid 28207848)
3. Sano M, Ernesto C, Thomas RG, et al. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study [J]. N Engl J Med, 1997, 336: 1216-1222. (Pubitemid 27183651)
4. Tabet N, Birks J, Grimley Evans J. Vitamin E for Alzheimer's disease [J]. Cochrane Database Syst Rev, 2000, (4): CD002854.
5. Wang YC, Zhang ZY, Jiang XZ. Traditional Chinese medicine baicalin pharmacological effect and application [J]. China Foreign Med Treat, 2009, 13: 158-160.
6. Song DG, Meng QG. Baicalin pharmacological effects commentary [J]. Chin Arch Tradit Chin Med, 2009, 127: 179-182.
7. Anekonda TS, Reddy PH. Neuronal protection by sirtuins in Alzheimer's disease [J]. J Neurochem, 2006, 96: 305-313.
8. Howitz KT, Bitterman KJ, Cohen HY, et al. Small molecule activators of Sirtuins extend Saccharomyces cerevisiae lifespan [J]. Nature, 2003, 425: 191-196. (Pubitemid 37150899)
9. Wang Y, Gao J, Qian JJ. SIRT1 and neurodegenerative diseases [J]. Chin Bull Life Sci, 2010, 1: 4-7.
10. Albani D, Polito L, Forloni G. Sirtuins as novel targets for Alzheimer's disease and other neurodegenerative disorders: experimental and genetic evidence [J]. J Alzheimers Dis, 2010, 19: 11-26.
11. Li LP, Wei Y, Cai J, et al. Hydrogen peroxide induced apoptosis in human vascular endothelial cells in vitro and expression of Caspase-3 [J]. J Shanxi Med, 2008, 37: 960-962.
12. Hu YP, Yuan DP. Effects of Qiancengta Decoction on learning memory ability and apoptosis in model rats with AD [J]. J Liaoning Chin Med, 2009, 36: 1807-1810.
13. Smale G, Nichols NR, Brady DR, et al. Evidence for apoptotic cell death in Alzheimer's disease [J]. Exp Neurol, 1995, 133: 225-230.
14. Lassmann H, Bancher C, Breitschopf H, et al. Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ [J]. Acta Neuropathol, 1995, 89: 35-41.
15. Su JH, Anderson AJ, Cummings BJ, et al. Immunohistochemical evidence for apoptosis in Alzheimer's disease [J]. Neuroreport, 1994, 5: 2529-2533.
16. 2 damage in cultured primary rat hippocampi neurons [J]. Chin J Integr Tradit Chin West Med, 2004, 10: 34-36.
17. Zhao BL. Free radicals, natural antioxidants and neurodegenerative disease [J]. Acta Biophys Sin, 2010, 26: 263-274.
18. Krabchi K, Lavoie J, Coullin P, et al. From the conception of the PRINS to its coronation [J]. Med Sci (Paris), 2004, 20: 465-473.
19. Csiszar A, Labinskyy N, Podlutsky A, et al. Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations [J]. Am J Physiol Heart Circ Physiol, 2008, 294: H2721-H2735.
20. 2-induced stress injury and expression of SIRT1 in PC12 cells [J]. J Trop Med, 2010, 10: 1051-1054.
21. Sun AY, Wang Q, Simonvi A, et al. Resveratrol as a therapeutic agent for neurodegenerative diseases [J]. Mol Neurobiol, 2010, 41: 375-383.
22. Hu YX. Progress in research of SIRT1 in cardiovascular system [J]. J Chin PLA Postgrad Med Sch, 2010, 31: 393-395.