Serum insulin, cortisol, leptin, neuropeptide Y, galanin and ghrelin levels in epileptic children receiving oxcarbazepine

European Journal of Paediatric Neurology

Volumn 15, Issue 6, 2011, Pages 527-531

  Cansu, Ali ^a   Serdaroglu, Ayse ^b   Cinaz, Peyami ^b  

^a KARADENIZ TECHNICAL UNIVERSITY   (Turkey)

^b GAZI UNIVERSITY FACULTY OF MEDICINE   (Turkey)

Author keywords

Galanin; Ghrelin; Leptin; Neuropeptide Y; Oxcarbazepine

Indexed keywords

GALANIN; GHRELIN; HYDROCORTISONE; INSULIN; LEPTIN; NEUROPEPTIDE Y; OXCARBAZEPINE;

ADOLESCENT; ARTICLE; BENIGN CHILDHOOD EPILEPSY; BODY MASS; BODY WEIGHT; CHILD; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; INSULIN BLOOD LEVEL; MALE; MONOTHERAPY; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SIDE EFFECT; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME;

ADOLESCENT; ANTICONVULSANTS; BLOOD GLUCOSE; BODY WEIGHT; CARBAMAZEPINE; CHILD; CHILD, PRESCHOOL; EPILEPSY; FEMALE; GALANIN; GHRELIN; HUMANS; HYDROCORTISONE; INSULIN; MALE; NEUROPEPTIDE Y;

EID: 81855193935     PISSN: 10903798     EISSN: 15322130     Source Type: Journal    
DOI: 10.1016/j.ejpn.2011.05.004     Document Type: Article

References (46)

1. A. Cansu Antiepileptic drugs and hormones in children Epilepsy Res 89 2010 89 95 [Review]
2. R.V. Considine Human leptin: an adipocyte hormone with weight-regulatory and endocrine functions Semin Vasc Med 5 2005 15 24 [Review] (Pubitemid 40721041)
3. V. Biton Effect of antiepileptic drugs on bodyweight: overview and clinical implications for the treatment of epilepsy CNS Drugs 17 2003 781 791 [Review] (Pubitemid 37082983)
4. E. Ben-Menachem Weight issues for people with epilepsy - a review Epilepsia 48 2007 42 45 [Review] (Pubitemid 350198229)
5. Y. Buggy, D. Layton, C. Fogg, and S.A. Shakir Safety profile of oxcarbazepine: results from a prescription-event monitoring study Epilepsia 51 2010 818 829
6. A. Beydoun, R.C. Sachdeo, W.E. Rosenfeld, G.L. Krauss, N. Sessler, P. Mesenbrink, L. Kramer, and J. D'Souza Oxcarbazepine monotherapy for partial-onset seizures: a multicenter, double-blind, clinical trial Neurology 54 2000 2245 2251 (Pubitemid 30416274)
7. J.W. Wheless, D.F. Clarke, A. Arzimanoglou, and D. Carpenter Treatment of pediatric epilepsy: European expert opinion 2007 Epileptic Disord 9 2007 353 412 [Review] (Pubitemid 351147653)
8. J. Rättyä, L. Vainionpää, M. Knip, P. Lanning, and J.I. Isojärvi The effects of valproate, carbamazepine, and oxcarbazepine on growth and sexual maturation in girls with epilepsy Pediatrics 103 1999 588 593 (Pubitemid 29274505)
9. E.S. Tecoma Oxcarbazepine Epilepsia 40 1999 S37 S46 [Review] (Pubitemid 29484588)
10. D. Schmidt, and C.E. Elger What is the evidence that oxcarbazepine and carbamazepine are distinctly different antiepileptic drugs? Epilepsy Behav 5 2004 627 635 (Pubitemid 40392577)
11. P. Kwan, G.J. Sills, and M.J. Brodie The mechanisms of action of commonly used antiepileptic drugs Pharmacol Ther 90 2001 21 34 (Pubitemid 32622838)
12. J.I. Isojärvi, J. Turkka, A.J. Pakarinen, M. Kotila, J. Rättyä, and V.V. Myllylä Thyroid function in men taking carbamazepine, oxcarbazepine, or valproate for epilepsy Epilepsia 42 2001 930 934 (Pubitemid 32783103)
13. A. Cansu, A. Serdarolu, O. Camurdan, T. Hirfanolu, A. Bideci, and K. Gücüyener The evaluation of thyroid functions, thyroid antibodies, and thyroid volumes in children with epilepsy during short-term administration of oxcarbazepine and valproate Epilepsia 47 2006 1855 1859 (Pubitemid 44730054)
14. T. Hirfanoglu, A. Serdaroglu, and O. Camurdan Thyroid function and volume in epileptic children using carbamazepine, oxcarbazepine and valproate Pediatr Int 49 2007 822 826 (Pubitemid 350197123)
15. A. Cansu, E. Yesilkaya, and A. Serdarolu Evaluation of bone turnover in epileptic children using oxcarbazepine Pediatr Neurol 39 2008 266 271
16. K. Mikkonen, M. Knip, A.J. Pakarinen, P. Lanning, J.I. Isojärvi, and L.K. Vainionpää Growth and lipid metabolism in girls and young women with epilepsy during pubertal maturation Epilepsia 46 2005 1114 1120 (Pubitemid 40962157)
17. A. Cansu, S.G. Giray, and A. Serdaroglu Effects of chronic treatment with valproate and oxcarbazepine on ovarian folliculogenesis in rats Epilepsia 49 2008 1192 1201 (Pubitemid 351991392)
18. A. Cansu, D. Erdogan, A. Serdaroglu, G. Take, Z.K. Coskun, and S.G. Gurgen Histologic and morphologic effects of valproic acid and oxcarbazepine on rat uterine and ovarian cells Epilepsia 51 2010 98 107
19. J.I. Isojärvi, E. Löfgren, and K.S. Juntunen Effect of epilepsy and antiepileptic drugs on male reproductive health Neurology 62 2004 247 253 (Pubitemid 38167133)
20. Z. Akta, A. Cansu, and D. Erdoan Retinal ganglion cell toxicity due to oxcarbazepine and valproic acid treatment in rat Seizure 18 2009 396 399
21. G.M. Raeven Role of insulin resistance in human disease Diabetes 37 1988 1595 1604
22. K. Aydin, A. Serdaroglu, C. Okuyaz, S. Bideci, and K. Gucuyener Serum insulin, leptin, and neuropeptide Y levels in epileptic children treated with valproate J Child Neurol 20 2005 848 851 (Pubitemid 43124479)
23. A. Sahu Leptin signaling in the hypothalamus: emphasis on energy homeostasis and leptin resistance Front Neuroendocrinol 24 2003 225 253 [Review] (Pubitemid 38064317)
24. A. Asakawa, A. Inui, and T. Kaga Antagonism of ghrelin receptor reduces food intake and body weight gain in mice Gut 52 2003 947 952 (Pubitemid 36765284)
25. Commission on Classification and Terminology of the International League Against Epilepsy Proposal for revised classification of epilepsies and epileptic syndromes Epilepsia 30 1989 389 399
26. M.L. Scheuer, and T.A. Pedley The evaluation and treatment of seizures N Engl J Med 323 1990 1468 1474 (Pubitemid 20384956)
27. W.A. Marshall, and J.M. Tanner Variations in patterns of pubertal changes in girls Arch Dis Child 44 1969 291 303
28. W.A. Marshall, and J.M. Tanner Variations in patterns of pubertal changes in boys Arch Dis Child 45 1970 13 23
29. O. Neyzi, P. Binyildiz, and H. Alp Growth standards for Turkish children: heights and weights Courier 29 1979 553 558
30. O. Neyzi, A. Furman, R. Bundak, H. Gunoz, F. Darendeliler, and F. Bas Growth references for Turkish children aged 6 to 18 years Acta Paediatr 95 2006 1635 1641 (Pubitemid 44863818)
31. S. Turan, A. Bereket, and A. Furman The effect of economic status on height, insulin-like growth factor (IGF)-I and IGF binding protein-3 concentrations in healthy Turkish children Eur J Clin Nutr 61 2007 752 758 (Pubitemid 47232355)
32. A. Bereket, S. Turan, and A. Omar Serum IGF-I and IGFBP-3 levels of Turkish children during childhood and adolescence: establishment of reference ranges with emphasis on puberty Horm Res 65 2006 96 105 (Pubitemid 43289475)
33. T.J. Cole, M.C. Bellizzi, K.M. Flegal, and W.H. Dietz Establishing a standard definition for child overweight and obesity worldwide; international survey BMJ 320 2000 1240 1243 (Pubitemid 30240471)
34. A. Verrotti, F. Basciani, M. De Simone, D. Trotta, G. Morgese, and F. Chiarelli Insulin resistance in epileptic girls who gain weight after therapy with valproic acid J Child Neurol 17 2002 265 268 (Pubitemid 34823422)
35. V. Pylvänen, M. Knip, A. Pakarinen, M. Kotila, J. Turkka, and J.I. Isojärvi Serum insulin and leptin levels in valproate-associated obesity Epilepsia 43 2002 514 517 (Pubitemid 34533707)
36. R.F. Shi, K.L. Wang, and Q.H. Li Changes of body weight and galanin in epileptic children treated with topiramate Zhonghua Er Ke Za Zhi 45 2007 199 202 [Abstract]
37. M. Rauchenzauner, A. Griesmacher, and T. Tatarczyk Chronic antiepileptic monotherapy, bone metabolism, and body composition in non-institutionalized children Dev Med Child Neurol 52 2010 283 288
38. K.L. Johnson, and C.R. Rn The hypothalamic-pituitary-adrenal axis in critical illness AACN Clin Issues 17 2006 39 49 [Review]
39. M. Leśkiewicz, B. Budziszewska, and W. Lasoń Endocrine effects of antiepileptic drugs Przegl Lek 65 2008 795 798 [Abstract]
40. W. Högler, S.A. Wudy, G. Luef, M.F. Hartmann, and M. Rauchenzauner Oxcarbazepine accelerates cortisol elimination via cytochrome P450 3A4 induction Arch Dis Child 95 2010 1065
41. D.C. Lagace, R.S. McLeod, and M.W. Nachtigal Valproic acid inhibits leptin secretion and reduces leptin Messenger ribonucleic acid levels in adipocytes Endocrinology 145 2004 5493 5503 (Pubitemid 39564589)
42. V. Pylvänen, M. Knip, and A.J. Pakarinen Fasting serum insulin and lipid levels in men with epilepsy Neurology 60 2003 571 574 (Pubitemid 36246071)
43. J. Wang, A. Akabayashi, and H. Yu Hypothalamic galanin: control by signals of fat metabolism Brain Res 31 1998 7 20 (Pubitemid 28410474)
44. H. Nagase, G. Bray, and D. York Effect of galanin and enterostatin on sympathetic nerve activity to interscapular brown adipose tissue Brain Res 12 1996 44 50 (Pubitemid 26063268)
45. D.E. Cummings, D.S. Weigle, and R.S. Frayo Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery N Engl J Med 346 2002 1623 1630 (Pubitemid 34755670)
46. F. Prodam, S. Bellone, and G. Casara Ghrelin levels are reduced in prepubertal epileptic children under treatment with carbamazepine or valproic acid Epilepsia 51 2010 312 315