Effect of penetration enhancer DMSO on in-vitro skin permeation of acyclovir transdermal microemulsion formulation

International Journal of Drug Delivery

Volumn 3, Issue 1, 2011, Pages 83-94

  Kumar, Brajesh ^a   Jain, S K ^a   Prajapati, S K ^a  

^a BUNDELKHAND UNIVERSITY   (India)

Author keywords

Acyclovir (ACV); DMSO; Ethanol; Penetration enhancer; Transdermal Microemulsion

Indexed keywords

ACICLOVIR; DIMETHYL SULFOXIDE;

ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; DRUG PENETRATION; DRUG SOLUBILITY; DRUG TRANSPORT; IN VITRO STUDY; MICROEMULSION; NONHUMAN; PARTICLE SIZE; RAT; SKIN PENETRATION; THERMODYNAMICS; THERMOSTABILITY; TRANSDERMAL DRUG ADMINISTRATION; WISTAR ALBINO GLAXO RAT; DRUG BIOAVAILABILITY; DRUG SAFETY; SKIN PERMEABILITY;

EID: 81855185669     PISSN: None     EISSN: 09750215     Source Type: Journal    
DOI: 10.5138/ijdd.2010.0975.0215.03057     Document Type: Article

References (27)

1. Williams AC, Barry BW. Penetration enhancers; Advanced Drug Delivery Reviews 2004; 56: 603-618.
2. Delgado-Charro MB, Iglesias-Vilas G, Blanco-Me'ndez J. Delivery of a hydrophilic solute though the skin from novel microemulsion systems. Eur. J. Pharm. Biopharm 1991; 43: 37-42.
3. Ktistis G, Niopas I. A study on the in-vitro percutaneous absorption of Propranolol from disperse systems. J. Pharm. Pharmacol 1998; 50: 413-418.
4. Kreilgaard M. Influence of microemulsions on cutaneous drug delivery; Advanced Drug Delivery Reviews 2002;54 Suppl. 1: S77-S98.
5. Dannielsson I, Lindman B. The definition of microemulsion; Colloids and Surfaces 1981; 3: 391-392.
6. El-laithy HM, El-shoboury KMF. The developmental cutina lipogel and gel microemulsion for topical administration of fluconazole. AAPS. Pharm. Sci. Tech 2002;3 (4) 35: 1-9.
7. Hoar TP, Schulman JH. Microemulsion. Transparent water-in-oil dispersions: the oleopathic hydro-micelle. Nature 1943; 152: 102-103.
8. Schulman JH, Stoeckenius W, Prince LM. Mechanism of formation and structure of micro emulsions by electron microscopy, J. Phys. Chem. 63 (1959) 1677-1680.
9. Tenjarla S., Microemulsios: An overview and Pharmaceutical applications. Crit. Rev. Therapeutic Drug Carrier Systems 1999; 16: 461-521.
10. Fini A, Bergamante V, Ceschel GC, Ronchi C, Alberto C, Moraes FD. Control of Transdermal Permeation of Hydrocortisone Acetate from Hydrophilic and Lipophilic Formulations. AAPS Pharm Sci Tech 2008; Vol. 9: No. 3, 762-768.
11. Shakeel F, Baboota S, Ahuja A, Khar RK, Ali M, Shafiq S. Nanoemulsions as Vehicles for Transdermal Delivery of Aceclofenac. AAPS Pharm Sci Tech 2007; 8 (4) Article 104: E1-E9
12. Gaitonde CD, Gui Z, Qu A, Anik S, Flack M, Vengroff. Merthod Validation for particle size distribution of nanoemulsion using Photon Correlation Spectroscopy. Nano Bio Corporation 2008; 27, 1-5.
13. Ammar HO, Ghorab M, El-Nahhas SA, Kamel R. Evaluation of chemical penetration enhancers for transdermal delivery of aspirin; Asian Journal of Pharmaceutical Sciences 2007; 2 (3): 96-105.
14. Panchagnula R, Salve PS, Thomas NS, Jain AK., Ramarao P. Transdermal delivery of naloxone: effect of water, propylene glycol, ethanol and their binary combinations on permeation though rat skin. International Journal of Pharmaceutics 2001; 219: 95-105.
15. Rhee YS, Coi J, Park E, Chi S. Transdermal delivery of ketopropfen using microemulsion; Int. J. Pharm 2001;228: 161-170.
16. Malcolmson C, Shindhu A, Satra C, Kantaria S, Lawrence MJ. Effect of nature of oil on the incorporation of testosterone propionate into non ionic oil-in-water microemulsion. J. Pharm. Sci. 1998; 87: 109-116.
17. Nagarsenker MS, Date AA. Parenteral microemulsion: An overview. Journal of pharmaceutics 2008; 355:19-30.
18. Shakeel F, Baboota S, Ahuja A, Ali J, Shafiq S. Design development and evaluation of novel nanoemulsion formulations for trnsdermal potential of celecoxib. Acia Pharm 2007; 57:315-332.
19. Naik A, Pechtold LA R M, Potts RO, Guy RH. Mechanism of oleic acid-induced skin penetration enhancement in vivo in humans; Journal of Controlled Release, 1995; 37: 299-306.
20. Tanojo H, Boelsma E, Junginger HE, Ponec M, Bodde HE. In vivo human skin permeability enhancement by oleic acid: a laser Doppler velocimetry study. Journal of controlled Release 1998; 58: 97-104.
21. Aboofazeli R, Zia H, Needham TE. Transdermal Delivery of Nicardipine: An Approach to In Vitro Permeation Enhancement. Drug Delivery 2002;9:239-247.
22. Walters KA, Brain KR, Green DM, James VG, Watkinson AC, Sands RH. Comparison of the transdermal delivery of estradiol from two gel formulations. Maturitas. Adv. Drug Deliv. Rev. 1998; 29:189-195.
23. Kogan A, Garti N. Microemulsions as transdermal drug delivery vehicles. Advances in Colloid and Interface Science 2006; 123-126, 369-385.
24. Pershing LK, Lambert LD, Knutson K. Mechanism of a ethanol-enhanced estradiol permeation across human skin in vivo. Pharm. Res. 1990; 7: 170-175.
25. Kligan AM. Topical pharmacology and toxicology of dimethylsulfoxide. J. Am. Med. Assoc. 1965; 193:796.
26. Oertel RP. Protein conformational changes induced in human stratum corneum by organic sulphoxides: an infrared spectroscopic investigation. Biopolymer 1997; 16: 2329-2345.
27. Anigbogu ANC, Williams AC, Barry BW, Edwards HGM. Fourier transforms Raman spectroscopy of interactions between the penetration enhancer dimethylsulphoxide and human stratum corneum. Int. J. Pharm 1995; 125: 265-282.