Antisense oligonucleotides targeting the RNA binding region of the NP gene inhibit replication of highly pathogenic avian influenza virus H5N1

International Immunopharmacology

Volumn 11, Issue 12, 2011, Pages 2057-2061

  Zhang, Tao ^a,b   Wang, Tie Cheng ^b   Zhao, Ping Sen ^a   Liang, Meng ^c   Gao, Yu Wei ^b   Yang, Song Tao ^b   Qin, Chuan ^a   Wang, Cheng Yu ^b   Xia, Xian Zhu ^a,b  

^a INSTITUTE OF LABORATORY ANIMAL SCIENCE   (China)

^b Institute of Military Veterinary   (China)

^c JILIN UNIVERSITY   (China)

Author keywords

AIV; AS ODNs; NP gene

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; LIPOSOME; NUCLEOPROTEIN; NUCLEOPROTEIN 267; NUCLEOPROTEIN 628; NUCLEOPROTEIN 749; RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN; CONTROLLED STUDY; DRUG SYNTHESIS; FEMALE; GENE REPLICATION; IMMUNOFLUORESCENCE; INFLUENZA VIRUS A H5N1; LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA BINDING; VIRUS GENE; VIRUS INHIBITION; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DOGS; FEMALE; INFLUENZA A VIRUS, H5N1 SUBTYPE; LIPOSOMES; LUNG; MICE; NUCLEOPROTEINS; OLIGONUCLEOTIDES, ANTISENSE; ORTHOMYXOVIRIDAE INFECTIONS; TREATMENT OUTCOME; VIRAL LOAD; VIRUS REPLICATION;

EID: 81855185304     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.08.019     Document Type: Article

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