The roles of extracellular signal-regulated kinase 1/2 pathway in regulating osteogenic differentiation of murine preosteoblasts MC3T3-E1 cells on roughened titanium surfaces

Journal of Biomedical Materials Research - Part A

Volumn 100 A, Issue 1, 2012, Pages 125-133

  Zhuang, Long Fei ^a,b   Jiang, Huan Huan ^a   Qiao, Shi Chong ^a   Appert, Christoph ^c   Si, Mi Si ^a   Gu, Ying Xin ^a   Lai, Hong Chang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c INSTITUT STRAUMANN AG   (Switzerland)

Author keywords

extracellular signal regulated kinase (ERK1 2); in vitro; osteoblast differentiation; surface roughness; titanium

Indexed keywords

ALKALINE PHOSPHATASE ACTIVITY; BONE-TO-IMPLANT CONTACT; CALCIUM DEPOSITION; CELL DIFFERENTIATION; CELL MORPHOLOGY; CONFOCAL MICROSCOPES; ENHANCING EFFECT; EXPRESSION LEVELS; EXTRACELLULAR SIGNAL-REGULATED KINASE; EXTRACELLULAR- SIGNAL-REGULATED KINASE 1/2; IN VITRO; IN-VIVO; INHIBITIVE EFFECTS; MC3T3-E1; MC3T3-E1 CELL; NEGATIVE REGULATORS; OSTEOBLAST DIFFERENTIATION; OSTEOBLASTIC DIFFERENTIATION; OSTEOCALCIN; OSTEOGENIC; OSTEOGENIC DIFFERENTIATION; OSTEOPROTEGERIN; OSTERIX; PREOSTEOBLASTS; REAL-TIME POLYMERASE CHAIN REACTION; ROUGH SURFACES; SCANNING ELECTRON MICROSCOPE; SIGNALING PATHWAYS; TITANIUM DISKS; TITANIUM SURFACES; TITANIUM-BASED IMPLANTS;

GENE EXPRESSION; MORPHOLOGY; OSTEOBLASTS; PHOSPHATASES; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SURFACE MORPHOLOGY; TITANIUM;

SURFACE ROUGHNESS;

ALKALINE PHOSPHATASE; CALCIUM; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OSTEOCALCIN; OSTEOPROTEGERIN; TITANIUM; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL STRUCTURE; CONFOCAL MICROSCOPY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; GENE EXPRESSION; MOUSE; NONHUMAN; OSTEOBLAST; REAL TIME POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY;

ALKALINE PHOSPHATASE; ANIMALS; BLOTTING, WESTERN; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL SHAPE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; MAP KINASE SIGNALING SYSTEM; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; OSTEOBLASTS; OSTEOGENESIS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; REAL-TIME POLYMERASE CHAIN REACTION; SURFACE PROPERTIES; TITANIUM;

EID: 81855183203     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.33247     Document Type: Article

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