Influence of Mild Metabolic Acidosis on Cardiac Contractility and Isoprenaline Response in Isolated Ovine Myocardium

Artificial Organs

Volumn 35, Issue 11, 2011, Pages 1065-1074

  Schotola, Hanna ^a   Sossalla, Samuel ^a   Rajab, Taufiek K ^b   Toischer, Karl ^a   Quintel, Michael ^a   Bauer, Martin ^a   Schmitto, Jan D ^c  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Catecholamine response; Contractility; Isolated myocardium; Mild acidosis; Sheep

Indexed keywords

HEART; HEMODYNAMICS; METABOLISM; PHYSIOLOGICAL MODELS; SURGERY;

ABSOLUTE VALUES; CATECHOLAMINE RESPONSE; CONTRACTILITY; FORCE AMPLITUDE; ISOLATED MYOCARDIUM; ISOPRENALINE; METABOLIC ACIDOSIS; MILD ACIDOSIS; MYOCARDIAL CONTRACTILITY; SHEEP;

PH;

ISOPRENALINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXPLANT; HEART BEAT; HEART MUSCLE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE RELAXATION; HEART RIGHT VENTRICLE; INOTROPISM; ISOLATED HEART; METABOLIC ACIDOSIS; NONHUMAN; PH; PRIORITY JOURNAL; SHEEP; TREATMENT RESPONSE;

EID: 81855166271     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2011.01390.x     Document Type: Article

References (56)

1. Schmitto JD, Kolat P, Ortmann P, etal. Early results of coronary artery bypass grafting with coronary endarterectomy for severe coronary artery disease. J Cardiothorac Surg 2009;4:52.
2. Schmitto JD, Mokashi SA, Chen FY, Chen EP. Aortic valve-sparing operations: state of the art. Curr Opin Cardiol 2010;25:102-6.
3. Schmitto JD, Mokashi SA, Cohn LH. Minimally-invasive valve surgery. J Am Coll Cardiol 2010;56:455-62.
4. Schmitto JD, Mohr FW, Cohn LH. Minimally invasive aortic valve replacement: how does this perform in high-risk patients? Curr Opin Cardiol 2011;26:118-22.
5. Gaskell WH. On the tonicity of the heart and blood vessels. J Physiol 1880;3:48-92.
6. Morad M, Trautwein W. The effect of the duration of the action potential on contraction in the mammalian heart muscle. Pflugers Arch Gesamte Physiol Menschen Tiere 1968;299:66-82.
7. Lorkovic H. Influence of changes in pH on the mechanical activity of cardiac muscle. Circ Res 1966;19:711-20.
8. Chesnais JM, Coraboeuf E, Sauviat MP, Vassas JM. Sensitivity to H, Li and Mg ions of the slow inward sodium current in frog atrial fibres. J Mol Cell Cardiol 1975;7:627-42.
9. Donaldson SK, Hermansen L, Bolles L. Differential, direct effects of H+ on Ca2+ -activated force of skinned fibers from the soleus, cardiac and adductor magnus muscles of rabbits. Pflugers Arch 1978;376:55-65.
10. Fabiato A, Fabiato F. Effects of pH on the myofilaments and the sarcoplasmic reticulum of skinned cells from cardiace and skeletal muscles. J Physiol 1978;276:233-55.
11. Kentish JC, Nayler WG. Ca2+-dependent tension generation in chemically "skinned" cardiac trabeculae: effect of pH [proceedings]. J Physiol 1978;284:90P-1P.
12. Solaro RJ, Lee JA, Kentish JC, Allen DG. Effects of acidosis on ventricular muscle from adult and neonatal rats. Circ Res 1988;63:779-87.
13. Kohlhardt M, Wirth K, Dudeck J. On the influence of metabolic alkalosis and metabolic acidosis on contractility of the isolated heart. Pflugers Arch Gesamte Physiol Menschen Tiere 1967;296:352-62.
14. Fry CH, Poole-Wilson PA. Effects of acid-base changes on excitation-contraction coupling in guinea-pig and rabbit cardiac ventricular muscle. J Physiol 1981;313:141-60.
15. Mattiazzi AR, Cingolani HE. Biphasic effect of hypercapnia on myocardial contractility. Arch Int Physiol Biochim 1977;85:11-25.
16. Serur JR, Skelton CL, Bodem R, Sonnenblick EH. Respiratory acid-base changes and myocardial contractility: interaction between calcium and hydrogen ions. J Mol Cell Cardiol 1976;8:823-36.
17. Harding SE, O'Gara P, Jones SM, Brown LA, Vescovo G, Poole-Wilson PA. Species dependence of contraction velocity in single isolated cardiac myocytes. Cardioscience 1990;1:49-53.
18. Camilion de Hurtado MC, Argel MI, Cingolani HE. Influence of acid-base alterations on myocardial sensitivity to catecholamines. Naunyn Schmiedebergs Arch Pharmacol 1981;317:219-24.
19. Andersen MN, Border JR, Mouritzen CV. Acidosis, catecholamines and cardiovascular dynamics: when does acidosis require correction? Ann Surg 1967;166:344-56.
20. Campbell GS, Houle DB, Crisp NW Jr, Weil MN, Brown EB Jr. Depressed response to intravenous sympathicomimetic agents in humans during acidosis. Dis Chest 1958;33:18-22.
21. Ford GD, Cline WH Jr, Fleming WW. Influence of lactic acidosis on cardiovascular response to sympathomimetic amines. Am J Physiol 1968;215:1123-9.
22. Schaer H. Influence of respiratory and metabolic acidosis on epinephrine-inotropic effect in isolated guinea pig atria. Pflugers Arch 1974;347:297-307.
23. Schmitto JD, Mokashi SA, Lee LS, etal. Large animal models of chronic heart failure. J Surg Res 2011;166:131-7.
24. Schmitto JD, Mokashi SA, Chen FY. Letter by Schmitto et al. regarding article "Large animal models of heart failure: a critical link in the translation of basic science to clinical practice." Circ Heart Fail 2010;3:e3, author reply e4.
25. Moainie SL, Gorman JH 3rd, Guy TS, etal. An ovine model of postinfarction dilated cardiomyopathy. Ann Thorac Surg 2002;74:753-60.
26. Thrower WB, Darby TD, Aldinger EE. Acid-base derangements and myocardial contractility. Effects as a complication of shock. Arch Surg 1961;82:56-65.
27. Whipple GH, Sheffield LT, Woodman EG, Thoephilis C, Friedman S. Reversible congestive heart failure due to rapid stimulation of the normal heart. Proc New Eng Cardiovasc Soc 1961;20:39-40.
28. Tessier D, Lajos P, Braunberger E, etal. Induction of chronic cardiac insufficiency by arteriovenous fistula and doxorubicin administration. J Card Surg 2003;18:307-11.
29. Schmitto JD, Ortmann P, Kolat P, etal. Chronic heart failure induced by multiple sequential microembolization in a sheep model. Int J Artif Organs 2008;31:348-53.
30. Schmitto JD, Coskun KO, Coskun ST, etal. Hemodynamic changes in a model of chronic heart failure induced by multiple sequential coronary microembolization in sheep. Artif Organs 2009;33:947-52.
31. Schmitto JD, Ortomann P, Vorkamp T, etal. Histological changes in a model of chronic heart failure induced by multiple sequential coronary microembolization in sheep. J Cardiovasc Surg (Torino) 2008;49:533-7.
32. Christiansen S, Jahn UR, Stypmann J, Redmann K, Scheld HH, Hammel D. Does a suitable animal model for research on partial left ventriculectomy exist? Animal models for PLV. Thorac Cardiovasc Surg 2001;49:259-67.
33. Sossalla S, Schmitto JD. Scientific teamwork-a particular approach. Kardiol Pol 2009;67:1421-3.
34. Harris AS. Delayed development of ventricular ectopic rhythms following experimental coronary occlusion. Circulation 1950;1:1318.
35. Heidrich F, Sossalla S, Schotola H, etal. The role of phospho-adenosine monophosphate-activated protein kinase and vascular endothelial growth factor in a model of chronic heart failure. Artif Organs 2010;34:969-79.
36. Schmitto JD, Ortmann P, Akdis M, etal. Miniaturized HIA microdiagonal pump as left ventricular assist device in a sheep model. ASAIO J. 2008;54:233-6.
37. Mokashi SA, Guan J, Wang D, etal. Preventing cardiac remodeling: the combination of cell-based therapy and cardiac support therapy preserves left ventricular function in rodent model of myocardial ischemia. J Thorac Cardiovasc Surg 2010;140:1374-80.
38. Schmitto JD, Mokashi SA, Lee LS, etal. A novel, innovative ovine model of chronic ischemic cardiomyopathy induced by multiple coronary ligations. Artif Organs 2010;34:918-22.
39. Hoppe H, Pavcnik D, Chuter TA, etal. Percutaneous technique for creation of tricuspid regurgitation in an ovine model. J Vasc Interv Radiol 2007;18(Pt 1):133-6.
40. Schmitto JD, Doerge H, Post H, etal. Progressive right ventricular failure is not explained by myocardial ischemia in a pig model of right ventricular pressure overload. Eur J Cardiothorac Surg 2009;35:229-34.
41. Downing SE, Talner NS, Gardner TH. Cardiovascular responses to metabolic acidosis. Am J Physiol 1965;208:237-42.
42. Sossalla S, Wagner S, Rasenack EC, etal. Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts-role of late sodium current and intracellular ion accumulation. J Mol Cell Cardiol 2008;45:32-43.
43. Smith HW. The actions of acids on turtle heart muscle with reference to the penetration of anions. Am J Physiol 1926;76:411-47.
44. Orchard CH, Kentish JC. Effects of changes of pH on the contractile function of cardiac muscle. Am J Physiol 1990;258(Pt 1):C967-81.
45. Hasenfuss G, Holubarsch C, Hermann HP, Astheimer K, Pieske B, Just H. Influence of the force-frequency relationship on haemodynamics and left ventricular function in patients with non-failing hearts and in patients with dilated cardiomyopathy. Eur Heart J 1994;15:164-70.
46. Pieske B, Kretschmann B, Meyer M, etal. Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy. Circulation 1995;92:1169-78.
47. Kaplan JA, Guffin AV, Yin A. The effects of metabolic acidosis and alkalosis on the response to sympathomimetic drugs in dogs. J Cardiothorac Anesth 1988;2:481-7.
48. Barenbrock M, Hausberg M, Matzkies F, de la Motte S, Schaefer RM. Effects of bicarbonate- and lactate-buffered replacement fluids on cardiovascular outcome in CVVH patients. Kidney Int 2000;58:1751-7.
49. Mathieu D, Neviere R, Billard V, Fleyfel M, Wattel F. Effects of bicarbonate therapy on hemodynamics and tissue oxygenation in patients with lactic acidosis: a prospective, controlled clinical study. Crit Care Med 1991;19:1352-6.
50. Forsythe SM, Schmidt GA. Sodium bicarbonate for the treatment of lactic acidosis. Chest 2000;117:260-7.
51. Moon PF, Gabor L, Gleed RD, Erb HN. Acid-base, metabolic, and hemodynamic effects of sodium bicarbonate or tromethamine administration in anesthetized dogs with experimentally induced metabolic acidosis. Am J Vet Res 1997;58:771-6.
52. Levraut J, Grimaud D. Treatment of metabolic acidosis. Curr Opin Crit Care 2003;9:260-5.
53. Kraut JA, Kurtz I. Use of base in the treatment of acute severe organic acidosis by nephrologists and critical care physicians: results of an online survey. Clin Exp Nephrol 2006;10:111-7.
54. Sossalla S, Schotola H, Schmitto JD, etal. Effects of different proton pump inhibitors on cardiac contractility in isolated human failing myocardium. J Cardiovasc Surg (Torino) 2011;52:437-43.
55. Sossalla S, Fluschnik N, Schotola H, etal. Inhibition of elevated Ca2+/calmodulin-dependent protein kinase II improves contractility in human failing myocardium. Circ Res 2010;107:1150-61.
56. Sossalla S, Kallmeyer B, Wagner S, etal. Altered Na(+) currents in atrial fibrillation effects of ranolazine on arrhythmias and contractility in human atrial myocardium. J Am Coll Cardiol 2010;55:2330-42.