The role of phospho-adenosine monophosphate-activated protein kinase and vascular endothelial growth factor in a model of chronic heart failure

Artificial Organs

Volumn 34, Issue 11, 2010, Pages 969-979

  Heidrich, Florian ^a   Sossalla, Samuel ^a   Schotola, Hanna ^a   Vorkamp, Tobias ^a   Ortmann, Philipp ^a   Popov, Aron F ^a   Coskun, Kasim O ^a   Rajab, Taufiek K ^b   Friedrich, Martin ^a   Sohns, Christian ^a   Hinz, Jose ^a   Bauer, Martin ^a   Quintel, Michael ^a   Schöndube, Friedrich A ^a   Schmitto, Jan D ^a,b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Adenosine monophosphate activated protein kinase; Animal model; Chronic heart failure; Coronary microembolization; Phospho adenosine monophosphate activated protein kinase; Sheep; Vascular endothelial growth factor

Indexed keywords

CELL ENGINEERING; ENDOTHELIAL CELLS; ENZYME ACTIVITY; HEART; PHOSPHORYLATION; POLYMERASE CHAIN REACTION;

ACTIVATED PROTEINS; ADENOSINE MONOPHOSPHATE; ADENOSINE MONOPHOSPHATE-ACTIVATED PROTEIN KINASE; ANIMAL MODEL; CHRONIC HEART FAILURES; CORONARY MICROEMBOLIZATION; PHOSPHO-ADENOSINE MONOPHOSPHATE-ACTIVATED PROTEIN KINASE; PROTEIN KINASE; SHEEP; VASCULAR ENDOTHELIAL GROWTH FACTOR;

ANIMALS;

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; MICROSPHERE; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ENERGY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; HEART EJECTION FRACTION; HEART FAILURE; HEART MUSCLE ISCHEMIA; HEART OUTPUT; HOMEOSTASIS; LEFT CORONARY ARTERY; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TACHYCARDIA; TACHYPNEA; UPREGULATION; WESTERN BLOTTING;

ANIMALIA; OVIS ARIES;

EID: 78649585153     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2010.01121.x     Document Type: Article

References (61)

1. Weir RA, McMurray JJ, Velazquez EJ. Epidemiology of heart failure and left ventricular systolic dysfunction after acute myocardial infarction: prevalence, clinical characteristics, and prognostic importance. Am J Cardiol 2006;97:13-25.
2. Davies MJ, Thomas AC. Plaque fissuring-the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina. Br Heart J 1985;53:363-73.
3. Falk E. Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis. Characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi. Br Heart J 1983;50:127-34.
4. Heusch G, Schulz R, Haude M, et al. Coronary microembolization. J Mol Cell Cardiol 2004;37:23-31.
5. Mehran R, Dangas G, Mintz GS, et al. Atherosclerotic plaque burden and CK-MB enzyme elevation after coronary interventions: intravascular ultrasound study of 2256 patients. Circulation 2000;101:604-10.
6. Bowers TR, Stewart RE, O'Neill WW, et al. Effect of rotablator atherectomy and adjunctive balloon angioplasty on coronary blood flow. Circulation 1997;95:1157-64.
7. Williams MJ, Dow CJ, Newell JB, et al. Prevalence and timing of regional myocardial dysfunction after rotational coronary atherectomy. J Am Coll Cardiol 1996;28:861-9.
8. Ricciardi MJ, Wu E, Davidson CJ, et al. Visualization of discrete microinfarction after percutaneous coronary intervention associated with mild creatine kinase-MB elevation. Circulation 2001;103:2780-3.
9. Schmitto J, Mokashi S, Lee L, et al. Large animals in chronic heart failure. J Surg Res 2009 (Epub ahead of print).
10. McDonald KM, Francis GS, Carlyle PF, et al. Hemodynamic, left ventricular structural and hormonal changes after discrete myocardial damage in the dog. J Am Coll Cardiol 1992;19:460-7.
11. Schmitto JD, Ortmann P, Kolat P, et al. Chronic heart failure induced by multiple sequential microembolization in a sheep model. Int J Artif Organs 2008;31:348-53.
12. Schmitto JD, Ortmann P, Vorkamp T, et al. Histological changes in a model of chronic heart failure induced by multiple sequential coronary microembolization in sheep. J Cardiovasc Surg (Torino) 2008;49:533-7.
13. Carlson CA, Kim KH. Regulation of hepatic acetyl coenzyme A carboxylase by phosphorylation and dephosphorylation. J Biol Chem 1973;248:378-80.
14. Reuben JS, Kosmatka M, Bardeesy N, et al. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc Natl Acad Sci U S A 2004;101:3329-35.
15. Arad M, Seidman CE, Seidman JG. AMP-activated protein kinase in the heart: role during health and disease. Circ Res 2007;100:474-88.
16. Dyck JR, Lopaschuk GD. AMPK alterations in cardiac physiology and pathology: enemy or ally? J Physiol 2006;574 (Pt 1):95-112.
17. Allard MF, Parsons HL, Saeedi R, Wambolt RB, Brownsey R. AMPK and metabolic adaptation by the heart to pressure overload. Am J Physiol Heart Circ Physiol 2007;292:H140-8.
18. Takagi H, Matsui Y, Hirotani S, Sakoda H, Asano T, Sadoshima J. AMPK mediates autophagy during myocardial ischemia in vivo. Circ Res 2007;100:914-22.
19. Matsui Y, Takagi H, Qu X, et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res 2007;100:914-22.
20. Terai K, Hiramoto Y, Masaki M, et al. AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress. Mol Cell Biol 2005;25:9554-75.
21. Sanz P. AMP-activated protein kinase: structure and regulation. Curr Protein Pept Sci 2008;5:478-92.
22. Folkman J, Merler E, Abernathy C, Williams G. Isolation of a tumor factor responsible for angiogenesis. J Exp Med 1971;133:275-88.
23. Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev 2004;25:581-611.
24. Olsson AK, Dimberg A, Kreuger J, Claesson-Welsh L. VEGF receptor signalling-in control of vascular function. Nat Rev Mol Cell Biol 2006;7:359-71.
25. Semenza GL, Agani F, Iyer N, et al. Hypoxia-inducible factor 1: from molecular biology to cardiopulmonary physiology. Chest 1998;114:40-5.
26. Rissanen TT, Vajanto I, Hiltunen MO, et al. Expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in ischemic skeletal muscle and its regeneration. Am J Pathol 2002;160:1393-403.
27. Sabbah HN, Stein PD, Kono T, et al. A canine model of chronic heart failure produced by multiple sequential coronary microembolizations. Am J Physiol 1991;260:H1379-84.
28. Franciosa JA, Heckel R, Limas C, Cohn JN. Progressive myocardial dysfunction associated with increased vascular resistance. Am J Physiol 1980;239:H477-82.
29. Smiseth OA, Lindal S, Mjos OD, Vik-Moh H, Jorgensen L. Progression of myocardial damage following coronary microembolization in dogs. Acta Pathol Microbiol Immunol Stand Sect A Suppl 1983;91:115-24.
30. Weber KT, Malinin TI, Dennison BH, Fuqua JM Jr, Speaker DM, Hastings FW. Experimental myocardial ischemia and infarction: production of diffuse myocardial lesions in unanesthetized calves. Am J Cardiol 1972;29:793-802.
31. Thomaz PG, Assad RS, Abduch MC, Marques E, Aiello VD, Stolf NA. Assessment of a new experimental model of isolated right ventricular failure. Artif Organs 2009;33:258-65.
32. Schmitto JD, Mokashi SA, Chen FY. Letter by Schmitto et al. regarding the article "Large animal models of heart failure: a critical link in the translation of basic science to clinical practice. Circ Heart Fail 2010;3:e3.
33. Dixon JA, Spinale FG. Large animal models of heart failure: a critical link in the translation of basic science to clinical practice. Circ Heart Fail 2009;2:262-71 (Review).
34. Schmitto JD, Coskun KO, Coskun ST, et al. Hemodynamic changes in a model of chronic heart failure induced by multiple sequential coronary microembolization in sheep. Artif Organs 2009;33:947-52. Epub 2009 Oct 10.
35. Watkins L Jr, Burton JA, Haber E, et al. The renin-angiotensin system in congestive failure in conscious dogs. J Clin Invest 1976;57:1606-17.
36. Lindal S, Smiseth OA, Mjos OD, Myklebust R, Jorgensen L. Reversible and irreversible changes in the dog heart during acute left ventricular failure due to experimental multifocal ischaemia. Acta Pathol Microbiol Immunol Stand Sect A Suppl 1986;94:177-86.
37. Belosjorow S, Schulz R, Dörge H, Schade FU, Heusch G. Endotoxin and ischemic preconditioning: TNF-α concentration and myocardial infarct development in rabbits. Am J Physiol 1999;46:H2470-5.
38. Dörge H, Schulz R, Belosjorow S, et al. Coronary microembolization: the role of TNF-alpha in contractile dysfunction. J Mol Cell Cardiol 2002;34:51-62.
39. Frederich M, Zhang L, Balschi JA. Hypoxia and AMP independently regulate AMP-activated protein kinase activity in heart. Am J Physiol Heart Circ Physiol 2005;288:2412-21.
40. Li J, Coven DL, Miller EJ, et al. Activation of AMPK alpha- and gamma-isoform complexes in the intact ischemic rat heart. Am J Physiol Heart Circ Physiol 2006;291:1927-34.
41. Wang Y, Gao E, Tao L, et al. AMP-activated protein kinase deficiency enhances myocardial ischemia/reperfusion injury but has minimal effect on the antioxidant/antinitrative protection of adiponectin. Circulation 2009;119:835-44.
42. Hardie DG. Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease. FEBS Lett 2008;582:81-90.
43. Lopaschuk GD. AMP-activated protein kinase control of energy metabolism in the ischemic heart. Int J Obes (Lond) 2008;4:29-35.
44. Nickel R, Schummer A, Seiferle E. Lehrbuch der Anatomie der Haustiere, Band III: Kreislaufsystem, Haut und Hautorgane. 4. Auflage; hrsg. v. Habermehl KH, Vollmerhaus B Medizinverlage, Stuttgart. 2005, 62-4.
45. Kim WG, Park JJ, Oh SI. Chronic heart failure model with sequential ligation of the homonymous artery and its diagonal branch in the sheep. ASAIO J 2001;47:667-72.
46. Wong AK, Howie J, Petrie JR, Lang CC. AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease. Clin Sci (Lond) 2009;116:607-20.
47. Matsumoto T, Mugishima H. Signal transduction via vascular endothelial growth factor (VEGF) receptors and their roles in atherogenesis. J Atheroscler Thromb 2006;13:130-5.
48. Minchenko A, Bauer T, Salceda S, Caro J. Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo. Lab Invest 1994;71:374-9.
49. Henry TD, Annex BH, McKendall GR, et al.; VIVA Investigators. The VIVA trial: vascular endothelial growth factor in ischemia for vascular angiogenesis. Circulation 2003;107:1359-65.
50. Schumacher B, Pecher P, Von Specht BU, Stegmann TJ. Induction of neoangiogenesis in ischemic myocardium by human growth factors. Circulation 1998;97:645-50.
51. Li J, Hampton T, Morgan JP, Simons M. Stretch-induced VEGF expression in the heart. J Clin Invest 1997;100:18-24.
52. Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev 2004;25:581-611.
53. Lee SH, Wolf PL, Escudero R, Deutsch R, Jamieson SW, Thistlethwaite PA. Early expression of angiogenesis factors in acute myocardial ischemia and infarction. N Engl J Med 2000;342:626-33.
54. Miraliakbari R, Francalancia NA, Lust RM, et al. Differences in myocardial and peripheral VEGF and KDR levels after acute ischemia. Ann Thorac Surg 2000;69:1750-3.
55. Mascio CE, Olison AK, Ralphe JC, Tomanek RJ, Scholz TD, Segar JL. Myocardial vascular and metabolic adaptations in chronically anemic fetal sheep. Am J Physiol Regul Integr Comp Physiol 2005;289:1736-45.
56. Sato K, Wu T, Laham RJ, et al. Efficacy of intracoronary or intravenous VEGF165 in a pig model of chronic myocardial ischemia. J Am Coll Cardiol 2001;37:616-23.
57. Schirmer SH, Van Nooijen FC, Piek JJ, Van Royen N. Stimulation of collateral artery growth: travelling further down the road to clinical application. Heart 2009;95:191-7.
58. Scholz D, Cai WJ, Schaper W. Arteriogenesis, a new concept of vascular adaptation in occlusive disease. Angiogenesis 2001;4:247-57.
59. Schmitto JD, Mokashi SA, Lee LS, et al. A novel, innovative ovine model of chronic ischemic cardiomyopathy induced by multiple coronary ligations. Artif Organs 2010;34:918-22.
60. Schmitto JD, Doerge H, Post H, Coulibaly M, Sellin C, Popov AF, et al. Progressive right ventricular failure is not explained by myocardial ischemia in a pig model of right ventricular pressure overload. Eur J Cardiothorac Surg 2009;35:229-34.
61. Schmitto JD, Ortmann P, Akdis M, Alekuzei H, Steinke K, Kolat P, et al. Miniaturized HIA microdiagonal pump as left ventricular assist device in a sheep model. ASAIO J 2008;54: 233-6.