Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice

Human Molecular Genetics

Volumn 20, Issue 24, 2011, Pages 4978-4990

  Judge, Luke M ^a   Arnett, Andrea L H ^a   Banks, Glen B ^a   Chamberlain, Jeffrey S ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE; DYSTROPHIN; DYSTROPHIN ISOFORM DP116; ISOPROTEIN; UNCLASSIFIED DRUG; UTROPHIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DISEASE SEVERITY; FEMALE; GENE EXPRESSION; GROWTH; HISTOPATHOLOGY; LIFESPAN; LOCOMOTION; MALE; MOUSE; MUSCLE CELL; MUSCLE CONTRACTION; MUSCLE FORCE; MUSCLE MASS; MUSCULAR DYSTROPHY; NEUROMUSCULAR SYNAPSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DOMAIN; QUADRICEPS FEMORIS MUSCLE; SKELETAL MUSCLE; TRANSGENE;

ANIMALS; BIOMECHANICS; CREATINE KINASE; DYSTROPHIN; ESOPHAGUS; FEMALE; LONGEVITY; MALE; MICE; MICE, INBRED MDX; MICE, TRANSGENIC; MUSCLE CONTRACTION; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, ANIMAL; NEUROMUSCULAR JUNCTION; ORGAN SIZE; PROTEIN ISOFORMS; SURVIVAL ANALYSIS; UTROPHIN;

EID: 81855166063     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr433     Document Type: Article

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