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Volumn 34, Issue 6, 2011, Pages 1251-1261

MR spectroscopy in schizophrenia

Author keywords

GABA; glutamate; metabolites; MR spectroscopy; neural circuitry; schizophrenia

Indexed keywords

4 AMINOBUTYRIC ACID; CHOLINE; CREATINE PHOSPHATE; DNA METHYLTRANSFERASE 1; DOPAMINE; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; GLUTAMIC ACID; GLUTAMINE; GLYCINE; GLYCINE TRANSPORTER INHIBITOR; LAMOTRIGINE; N ACETYLASPARTYLGLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NAPHTHALENE; PROTEIN INHIBITOR; REELIN; TOPIRAMATE; UNCLASSIFIED DRUG;

EID: 81755177861     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.22787     Document Type: Review
Times cited : (23)

References (79)
  • 2
    • 0033638576 scopus 로고    scopus 로고
    • Catching up on schizophrenia: Natural history and neurobiology
    • Lewis DA, Lieberman JA,. Catching up on schizophrenia: natural history and neurobiology. Neuron 2000; 28: 325-334.
    • (2000) Neuron , vol.28 , pp. 325-334
    • Lewis, D.A.1    Lieberman, J.A.2
  • 3
    • 68949180394 scopus 로고    scopus 로고
    • Schizophrenia
    • van Os J, Kapur S,. Schizophrenia. Lancet 2009; 374: 635-645.
    • (2009) Lancet , vol.374 , pp. 635-645
    • Van Os, J.1    Kapur, S.2
  • 5
    • 65249107131 scopus 로고    scopus 로고
    • Schizophrenia from a neural circuitry perspective: Advancing toward rational pharmacological therapies
    • Lewis DA, Sweet RA,. Schizophrenia from a neural circuitry perspective: advancing toward rational pharmacological therapies. J Clin Invest 2009; 119: 706-716.
    • (2009) J Clin Invest , vol.119 , pp. 706-716
    • Lewis, D.A.1    Sweet, R.A.2
  • 6
    • 84857006612 scopus 로고    scopus 로고
    • Epigenetics of schizophrenia
    • Akbarian S,. Epigenetics of schizophrenia. Curr Top Behav Neurosci 2010; 4: 611-628.
    • (2010) Curr Top Behav Neurosci , vol.4 , pp. 611-628
    • Akbarian, S.1
  • 7
    • 33847325243 scopus 로고    scopus 로고
    • Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder
    • Veldic M, Kadriu B, Maloku E, et al. Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder. Schizophr Res 2007; 91: 51-61.
    • (2007) Schizophr Res , vol.91 , pp. 51-61
    • Veldic, M.1    Kadriu, B.2    Maloku, E.3
  • 9
    • 0000866323 scopus 로고
    • Sulla struttura della sostanza grigia dell cervello
    • Golgi C,. Sulla struttura della sostanza grigia dell cervello. Gazz Med Lombarda 1873; 33: 244-246.
    • (1873) Gazz Med Lombarda , vol.33 , pp. 244-246
    • Golgi, C.1
  • 13
    • 84984929035 scopus 로고
    • Ueber einige neuere Forschungen im Gebiete der Anatomie des Centralnervensystems
    • 1244-1246, 1287-1289, 1331-1332, 1350-1356.
    • von Waldeyer-Hartz HWG,. Ueber einige neuere Forschungen im Gebiete der Anatomie des Centralnervensystems. Deutsche medicinische Wochenschrift 1891; 17: 1213-1218, 1244-1246, 1287-1289, 1331-1332, 1350-1356.
    • (1891) Deutsche Medicinische Wochenschrift , vol.17 , pp. 1213-1218
    • Von Waldeyer-Hartz, H.W.G.1
  • 14
    • 75549084615 scopus 로고    scopus 로고
    • Centenary of Brodmann's map-conception and fate
    • Zilles K, Amunts K,. Centenary of Brodmann's map-conception and fate. Nat Rev Neurosci 2010; 11: 139-145.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 139-145
    • Zilles, K.1    Amunts, K.2
  • 16
    • 70449153603 scopus 로고
    • Modality and topographic properties of single neurons of cat's somatic sensory cortex
    • Mountcastle VB,. Modality and topographic properties of single neurons of cat's somatic sensory cortex. J Neurophysiol 1957; 20: 408-434.
    • (1957) J Neurophysiol , vol.20 , pp. 408-434
    • Mountcastle, V.B.1
  • 17
    • 0033995327 scopus 로고    scopus 로고
    • Non-invasive visualization of cortical columns by fMRI
    • Grinvald A, Slovin H, Vanzetta I,. Non-invasive visualization of cortical columns by fMRI. Nat Neurosci 2000; 3: 105-107.
    • (2000) Nat Neurosci , vol.3 , pp. 105-107
    • Grinvald, A.1    Slovin, H.2    Vanzetta, I.3
  • 18
    • 33747872904 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders
    • Akbarian S, Huang HS,. Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders. Brain Res Rev 2006; 52: 293-304.
    • (2006) Brain Res Rev , vol.52 , pp. 293-304
    • Akbarian, S.1    Huang, H.S.2
  • 19
    • 0032574841 scopus 로고    scopus 로고
    • A subclass of prefrontal gamma-aminobutyric acid axon terminals are selectively altered in schizophrenia
    • Woo TU, Whitehead RE, Melchitzky DS, Lewis DA,. A subclass of prefrontal gamma-aminobutyric acid axon terminals are selectively altered in schizophrenia. Proc Natl Acad Sci U S A 1998; 95: 5341-5346.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 5341-5346
    • Woo, T.U.1    Whitehead, R.E.2    Melchitzky, D.S.3    Lewis, D.A.4
  • 20
    • 0036569197 scopus 로고    scopus 로고
    • A selective decrease in the relative density of parvalbumin- immunoreactive neurons in the hippocampus in schizophrenia
    • Zhang ZJ, Reynolds GP,. A selective decrease in the relative density of parvalbumin-immunoreactive neurons in the hippocampus in schizophrenia. Schizophr Res 2002; 55: 1-10.
    • (2002) Schizophr Res , vol.55 , pp. 1-10
    • Zhang, Z.J.1    Reynolds, G.P.2
  • 21
    • 42749095376 scopus 로고    scopus 로고
    • Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
    • Lisman JE, Coyle JT, Green RW, et al. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci 2008; 31: 234-242.
    • (2008) Trends Neurosci , vol.31 , pp. 234-242
    • Lisman, J.E.1    Coyle, J.T.2    Green, R.W.3
  • 23
    • 0141889804 scopus 로고    scopus 로고
    • Reversal of phencyclidine-induced prepulse inhibition deficits by clozapine in monkeys
    • Linn GS, Negi SS, Gerum SV, Javitt DC,. Reversal of phencyclidine-induced prepulse inhibition deficits by clozapine in monkeys. Psychopharmacology (Berl) 2003; 169: 234-239.
    • (2003) Psychopharmacology (Berl) , vol.169 , pp. 234-239
    • Linn, G.S.1    Negi, S.S.2    Gerum, S.V.3    Javitt, D.C.4
  • 24
    • 13444267336 scopus 로고    scopus 로고
    • Effects of ketamine on anterior cingulate glutamate metabolism in healthy humans: A 4-T proton MRS study
    • Rowland LM, Bustillo JR, Mullins PG, et al. Effects of ketamine on anterior cingulate glutamate metabolism in healthy humans: a 4-T proton MRS study. Am J Psychiatry 2005; 162: 394-396.
    • (2005) Am J Psychiatry , vol.162 , pp. 394-396
    • Rowland, L.M.1    Bustillo, J.R.2    Mullins, P.G.3
  • 25
    • 0028897733 scopus 로고
    • Clinical experience with excitatory amino acid antagonist drugs
    • Muir KW, Lees KR,. Clinical experience with excitatory amino acid antagonist drugs. Stroke 1995; 26: 503-513.
    • (1995) Stroke , vol.26 , pp. 503-513
    • Muir, K.W.1    Lees, K.R.2
  • 26
    • 0034054949 scopus 로고    scopus 로고
    • Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: Support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists
    • Anand A, Charney DS, Oren DA, et al. Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists. Arch Gen Psychiatry 2000; 57: 270-276.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 270-276
    • Anand, A.1    Charney, D.S.2    Oren, D.A.3
  • 27
    • 20944439080 scopus 로고    scopus 로고
    • Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects
    • Krystal JH, Abi-Saab W, Perry E, et al. Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects. Psychopharmacology (Berl) 2005; 179: 303-309.
    • (2005) Psychopharmacology (Berl) , vol.179 , pp. 303-309
    • Krystal, J.H.1    Abi-Saab, W.2    Perry, E.3
  • 28
    • 34948858402 scopus 로고    scopus 로고
    • Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
    • Patil ST, Zhang L, Martenyi F, et al. Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat Med 2007; 13: 1102-1107.
    • (2007) Nat Med , vol.13 , pp. 1102-1107
    • Patil, S.T.1    Zhang, L.2    Martenyi, F.3
  • 29
    • 23944506267 scopus 로고    scopus 로고
    • Topiramate add-on in treatment-resistant schizophrenia: A randomized, double-blind, placebo-controlled, crossover trial
    • Tiihonen J, Halonen P, Wahlbeck K, et al. Topiramate add-on in treatment-resistant schizophrenia: a randomized, double-blind, placebo-controlled, crossover trial. J Clin Psychiatry 2005; 66: 1012-1015.
    • (2005) J Clin Psychiatry , vol.66 , pp. 1012-1015
    • Tiihonen, J.1    Halonen, P.2    Wahlbeck, K.3
  • 30
    • 52949152393 scopus 로고    scopus 로고
    • Longitudinal progression of negative symptoms in schizophrenia: A new look at an old problem
    • Kelley ME, Haas GL, van Kammen DP,. Longitudinal progression of negative symptoms in schizophrenia: a new look at an old problem. Schizophr Res 2008; 105: 188-196.
    • (2008) Schizophr Res , vol.105 , pp. 188-196
    • Kelley, M.E.1    Haas, G.L.2    Van Kammen, D.P.3
  • 31
    • 0035949688 scopus 로고    scopus 로고
    • Mapping adolescent brain change reveals dynamic wave of accelerated gray matter loss in very early-onset schizophrenia
    • Thompson PM, Vidal C, Giedd JN, et al. Mapping adolescent brain change reveals dynamic wave of accelerated gray matter loss in very early-onset schizophrenia. Proc Natl Acad Sci U S A 2001; 98: 11650-11655.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 11650-11655
    • Thompson, P.M.1    Vidal, C.2    Giedd, J.N.3
  • 32
    • 79951682529 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy and illness stage in schizophrenia-a systematic review and meta-analysis
    • Brugger S, Davis JM, Leucht S, Stone JM,. Proton magnetic resonance spectroscopy and illness stage in schizophrenia-a systematic review and meta-analysis. Biol Psychiatry 2011; 69: 495-503.
    • (2011) Biol Psychiatry , vol.69 , pp. 495-503
    • Brugger, S.1    Davis, J.M.2    Leucht, S.3    Stone, J.M.4
  • 33
    • 30744443492 scopus 로고    scopus 로고
    • Measurement of brain metabolites by 1H magnetic resonance spectroscopy in patients with schizophrenia: A systematic review and meta-analysis
    • Steen RG, Hamer RM, Lieberman JA,. Measurement of brain metabolites by 1H magnetic resonance spectroscopy in patients with schizophrenia: a systematic review and meta-analysis. Neuropsychopharmacology 2005; 30: 1949-1962.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1949-1962
    • Steen, R.G.1    Hamer, R.M.2    Lieberman, J.A.3
  • 34
    • 34249281667 scopus 로고    scopus 로고
    • Reproducibility of GABA measurements using 2D J-resolved magnetic resonance spectroscopy
    • Lymer K, Haga K, Marshall I, Sailasuta N, Wardlaw J,. Reproducibility of GABA measurements using 2D J-resolved magnetic resonance spectroscopy. Magn Reson Imaging 2007; 25: 634-640.
    • (2007) Magn Reson Imaging , vol.25 , pp. 634-640
    • Lymer, K.1    Haga, K.2    Marshall, I.3    Sailasuta, N.4    Wardlaw, J.5
  • 35
    • 0028535504 scopus 로고
    • 1H magnetic resonance spectroscopy characterization of neuronal dysfunction in drug-naive, chronic schizophrenia
    • Choe BY, Kim KT, Suh TS, et al. 1H magnetic resonance spectroscopy characterization of neuronal dysfunction in drug-naive, chronic schizophrenia. Acad Radiol 1994; 1: 211-216.
    • (1994) Acad Radiol , vol.1 , pp. 211-216
    • Choe, B.Y.1    Kim, K.T.2    Suh, T.S.3
  • 36
    • 0029882536 scopus 로고    scopus 로고
    • Observation of metabolic changes in chronic schizophrenia after neuroleptic treatment by in vivo hydrogen magnetic resonance spectroscopy
    • Choe BY, Suh TS, Shinn KS, Lee CW, Lee C, Paik IH,. Observation of metabolic changes in chronic schizophrenia after neuroleptic treatment by in vivo hydrogen magnetic resonance spectroscopy. Invest Radiol 1996; 31: 345-352.
    • (1996) Invest Radiol , vol.31 , pp. 345-352
    • Choe, B.Y.1    Suh, T.S.2    Shinn, K.S.3    Lee, C.W.4    Lee, C.5    Paik, I.H.6
  • 37
    • 0034657022 scopus 로고    scopus 로고
    • Hippocampal pathology in schizophrenia: Magnetic resonance imaging and spectroscopy studies
    • Kegeles LS, Shungu DC, Anjilvel S, et al. Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies. Psychiatry Res 2000; 98: 163-175.
    • (2000) Psychiatry Res , vol.98 , pp. 163-175
    • Kegeles, L.S.1    Shungu, D.C.2    Anjilvel, S.3
  • 38
    • 63449138812 scopus 로고    scopus 로고
    • Duration of untreated psychosis and proton magnetic resonance spectroscopy (1H-MRS) findings in first-episode schizophrenia
    • Galinska B, Szulc A, Tarasow E, et al. Duration of untreated psychosis and proton magnetic resonance spectroscopy (1H-MRS) findings in first-episode schizophrenia. Med Sci Monit 2009; 15: CR82-CR88.
    • (2009) Med Sci Monit , vol.15
    • Galinska, B.1    Szulc, A.2    Tarasow, E.3
  • 40
    • 67349168697 scopus 로고    scopus 로고
    • Reduction of brain gamma-aminobutyric acid (GABA) concentrations in early-stage schizophrenia patients: 3T Proton MRS study
    • Goto N, Yoshimura R, Moriya J, et al. Reduction of brain gamma-aminobutyric acid (GABA) concentrations in early-stage schizophrenia patients: 3T Proton MRS study. Schizophr Res 2009; 112: 192-193.
    • (2009) Schizophr Res , vol.112 , pp. 192-193
    • Goto, N.1    Yoshimura, R.2    Moriya, J.3
  • 43
    • 75949115370 scopus 로고    scopus 로고
    • GABA concentration in schizophrenia patients and the effects of antipsychotic medication: A proton magnetic resonance spectroscopy study
    • Tayoshi S, Nakataki M, Sumitani S, et al. GABA concentration in schizophrenia patients and the effects of antipsychotic medication: a proton magnetic resonance spectroscopy study. Schizophr Res 2010; 117: 83-91.
    • (2010) Schizophr Res , vol.117 , pp. 83-91
    • Tayoshi, S.1    Nakataki, M.2    Sumitani, S.3
  • 44
    • 33846238600 scopus 로고    scopus 로고
    • How do glial-neuronal interactions fit into current neurotransmitter hypotheses of schizophrenia?
    • Kondziella D, Brenner E, Eyjolfsson EM, Sonnewald U,. How do glial-neuronal interactions fit into current neurotransmitter hypotheses of schizophrenia? Neurochem Int 2007; 50: 291-301.
    • (2007) Neurochem Int , vol.50 , pp. 291-301
    • Kondziella, D.1    Brenner, E.2    Eyjolfsson, E.M.3    Sonnewald, U.4
  • 45
    • 0030610611 scopus 로고    scopus 로고
    • In vitro 1H-magnetic resonance spectroscopy of postmortem brains with schizophrenia
    • Omori M, Pearce J, Komoroski RA, et al. In vitro 1H-magnetic resonance spectroscopy of postmortem brains with schizophrenia. Biol Psychiatry 1997; 42: 359-366.
    • (1997) Biol Psychiatry , vol.42 , pp. 359-366
    • Omori, M.1    Pearce, J.2    Komoroski, R.A.3
  • 46
    • 7244220611 scopus 로고    scopus 로고
    • Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS
    • Theberge J, Al-Semaan Y, Williamson PC, et al. Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS. Am J Psychiatry 2003; 160: 2231-2233.
    • (2003) Am J Psychiatry , vol.160 , pp. 2231-2233
    • Theberge, J.1    Al-Semaan, Y.2    Williamson, P.C.3
  • 47
    • 0036843574 scopus 로고    scopus 로고
    • Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers
    • Theberge J, Bartha R, Drost DJ, et al. Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers. Am J Psychiatry 2002; 159: 1944-1946.
    • (2002) Am J Psychiatry , vol.159 , pp. 1944-1946
    • Theberge, J.1    Bartha, R.2    Drost, D.J.3
  • 48
    • 39149141357 scopus 로고    scopus 로고
    • Frontolimbic glutamate alterations in first episode schizophrenia: Evidence from a magnetic resonance spectroscopy study
    • Olbrich HM, Valerius G, Rusch N, et al. Frontolimbic glutamate alterations in first episode schizophrenia: evidence from a magnetic resonance spectroscopy study. World J Biol Psychiatry 2008; 9: 59-63.
    • (2008) World J Biol Psychiatry , vol.9 , pp. 59-63
    • Olbrich, H.M.1    Valerius, G.2    Rusch, N.3
  • 49
    • 2942558677 scopus 로고    scopus 로고
    • 3-T proton MRS investigation of glutamate and glutamine in adolescents at high genetic risk for schizophrenia
    • Tibbo P, Hanstock C, Valiakalayil A, Allen P,. 3-T proton MRS investigation of glutamate and glutamine in adolescents at high genetic risk for schizophrenia. Am J Psychiatry 2004; 161: 1116-1118.
    • (2004) Am J Psychiatry , vol.161 , pp. 1116-1118
    • Tibbo, P.1    Hanstock, C.2    Valiakalayil, A.3    Allen, P.4
  • 50
    • 35048894824 scopus 로고    scopus 로고
    • Longitudinal grey-matter and glutamatergic losses in first-episode schizophrenia
    • Theberge J, Williamson KE, Aoyama N, et al. Longitudinal grey-matter and glutamatergic losses in first-episode schizophrenia. Br J Psychiatry 2007; 191: 325-334.
    • (2007) Br J Psychiatry , vol.191 , pp. 325-334
    • Theberge, J.1    Williamson, K.E.2    Aoyama, N.3
  • 51
    • 11844304922 scopus 로고    scopus 로고
    • Evidence for glutamatergic neuronal dysfunction in the prefrontal cortex in chronic but not in first-episode patients with schizophrenia: A proton magnetic resonance spectroscopy study
    • Ohrmann P, Siegmund A, Suslow T, et al. Evidence for glutamatergic neuronal dysfunction in the prefrontal cortex in chronic but not in first-episode patients with schizophrenia: a proton magnetic resonance spectroscopy study. Schizophr Res 2005; 73: 153-157.
    • (2005) Schizophr Res , vol.73 , pp. 153-157
    • Ohrmann, P.1    Siegmund, A.2    Suslow, T.3
  • 52
    • 77956903987 scopus 로고    scopus 로고
    • Assessments of function and biochemistry of the anterior cingulate cortex in schizophrenia
    • Reid MA, Stoeckel LE, White DM, et al. Assessments of function and biochemistry of the anterior cingulate cortex in schizophrenia. Biol Psychiatry 2010; 68: 625-633.
    • (2010) Biol Psychiatry , vol.68 , pp. 625-633
    • Reid, M.A.1    Stoeckel, L.E.2    White, D.M.3
  • 53
    • 34447270812 scopus 로고    scopus 로고
    • Evidence for neuronal dysfunction in the anterior cingulate of patients with schizophrenia: A proton magnetic resonance spectroscopy study at 3 T
    • Wood SJ, Yucel M, Wellard RM, et al. Evidence for neuronal dysfunction in the anterior cingulate of patients with schizophrenia: a proton magnetic resonance spectroscopy study at 3 T. Schizophr Res 2007; 94: 328-331.
    • (2007) Schizophr Res , vol.94 , pp. 328-331
    • Wood, S.J.1    Yucel, M.2    Wellard, R.M.3
  • 54
    • 27544447486 scopus 로고    scopus 로고
    • Increased prefrontal and hippocampal glutamate concentration in schizophrenia: Evidence from a magnetic resonance spectroscopy study
    • van Elst LT, Valerius G, Buchert M, et al. Increased prefrontal and hippocampal glutamate concentration in schizophrenia: evidence from a magnetic resonance spectroscopy study. Biol Psychiatry 2005; 58: 724-730.
    • (2005) Biol Psychiatry , vol.58 , pp. 724-730
    • Van Elst, L.T.1    Valerius, G.2    Buchert, M.3
  • 55
    • 34247612982 scopus 로고    scopus 로고
    • Regarding "increased prefrontal and hippocampal glutamate concentration in schizophrenia: Evidence from a magnetic resonance spectroscopy study"
    • author reply 1219-1220.
    • Theberge J, Jensen JE, Rowland LM,. Regarding "Increased prefrontal and hippocampal glutamate concentration in schizophrenia: evidence from a magnetic resonance spectroscopy study". Biol Psychiatry 2007; 61: 1218-1219; author reply 1219-1220.
    • (2007) Biol Psychiatry , vol.61 , pp. 1218-1219
    • Theberge, J.1    Jensen, J.E.2    Rowland, L.M.3
  • 56
    • 36549069306 scopus 로고    scopus 로고
    • Brain metabolite abnormalities in the white matter of elderly schizophrenic subjects: Implication for glial dysfunction
    • Chang L, Friedman J, Ernst T, Zhong K, Tsopelas ND, Davis K,. Brain metabolite abnormalities in the white matter of elderly schizophrenic subjects: implication for glial dysfunction. Biol Psychiatry 2007; 62: 1396-1404.
    • (2007) Biol Psychiatry , vol.62 , pp. 1396-1404
    • Chang, L.1    Friedman, J.2    Ernst, T.3    Zhong, K.4    Tsopelas, N.D.5    Davis, K.6
  • 57
    • 67349088001 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy in subjects with high genetic risk of schizophrenia: Investigation of anterior cingulate, dorsolateral prefrontal cortex and thalamus
    • Yoo SY, Yeon S, Choi CH, et al. Proton magnetic resonance spectroscopy in subjects with high genetic risk of schizophrenia: investigation of anterior cingulate, dorsolateral prefrontal cortex and thalamus. Schizophr Res 2009; 111: 86-93.
    • (2009) Schizophr Res , vol.111 , pp. 86-93
    • Yoo, S.Y.1    Yeon, S.2    Choi, C.H.3
  • 58
    • 0022611408 scopus 로고
    • Antagonism of phencyclidine-induced hyperactivity by glycine in mice
    • Toth E, Lajtha A,. Antagonism of phencyclidine-induced hyperactivity by glycine in mice. Neurochem Res 1986; 11: 393-400.
    • (1986) Neurochem Res , vol.11 , pp. 393-400
    • Toth, E.1    Lajtha, A.2
  • 59
    • 44249119348 scopus 로고    scopus 로고
    • Glycine and D: -serine, but not D: -cycloserine, attenuate prepulse inhibition deficits induced by NMDA receptor antagonist MK-801
    • Kanahara N, Shimizu E, Ohgake S, et al. Glycine and D: -serine, but not D: -cycloserine, attenuate prepulse inhibition deficits induced by NMDA receptor antagonist MK-801. Psychopharmacology (Berl) 2008; 198: 363-374.
    • (2008) Psychopharmacology (Berl) , vol.198 , pp. 363-374
    • Kanahara, N.1    Shimizu, E.2    Ohgake, S.3
  • 60
    • 67651083407 scopus 로고    scopus 로고
    • Oral glycine administration increases brain glycine/creatine ratios in men: A proton magnetic resonance spectroscopy study
    • Kaufman MJ, Prescot AP, Ongur D, et al. Oral glycine administration increases brain glycine/creatine ratios in men: a proton magnetic resonance spectroscopy study. Psychiatry Res 2009; 173: 143-149.
    • (2009) Psychiatry Res , vol.173 , pp. 143-149
    • Kaufman, M.J.1    Prescot, A.P.2    Ongur, D.3
  • 61
    • 78149284957 scopus 로고    scopus 로고
    • Glycine transport inhibitors for the treatment of schizophrenia
    • Hashimoto K,. Glycine transport inhibitors for the treatment of schizophrenia. Open Med Chem J 2010; 4: 10-19.
    • (2010) Open Med Chem J , vol.4 , pp. 10-19
    • Hashimoto, K.1
  • 62
    • 0030846501 scopus 로고    scopus 로고
    • Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS
    • Pouwels PJ, Frahm J,. Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS. NMR Biomed 1997; 10: 73-78.
    • (1997) NMR Biomed , vol.10 , pp. 73-78
    • Pouwels, P.J.1    Frahm, J.2
  • 63
    • 0346057787 scopus 로고    scopus 로고
    • Glutamate carboxypeptidase II gene expression in the human frontal and temporal lobe in schizophrenia
    • Ghose S, Weickert CS, Colvin SM, et al. Glutamate carboxypeptidase II gene expression in the human frontal and temporal lobe in schizophrenia. Neuropsychopharmacology 2004; 29: 117-125.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 117-125
    • Ghose, S.1    Weickert, C.S.2    Colvin, S.M.3
  • 64
    • 0037838880 scopus 로고    scopus 로고
    • N-acetylaspartate and N-Acetylaspartylglutamate deficits in superior temporal cortex in schizophrenia and bipolar disorder: A postmortem study
    • Nudmamud S, Reynolds LM, Reynolds GP,. N-acetylaspartate and N-Acetylaspartylglutamate deficits in superior temporal cortex in schizophrenia and bipolar disorder: a postmortem study. Biol Psychiatry 2003; 53: 1138-1141.
    • (2003) Biol Psychiatry , vol.53 , pp. 1138-1141
    • Nudmamud, S.1    Reynolds, L.M.2    Reynolds, G.P.3
  • 65
    • 0028875197 scopus 로고
    • Abnormal excitatory neurotransmitter metabolism in schizophrenic brains
    • Tsai G, Passani LA, Slusher BS, et al. Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. Arch Gen Psychiatry 1995; 52: 829-836.
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 829-836
    • Tsai, G.1    Passani, L.A.2    Slusher, B.S.3
  • 66
    • 11844305557 scopus 로고    scopus 로고
    • Chronic phencyclidine administration induces schizophrenia-like changes in N-acetylaspartate and N-acetylaspartylglutamate in rat brain
    • Reynolds LM, Cochran SM, Morris BJ, Pratt JA, Reynolds GP,. Chronic phencyclidine administration induces schizophrenia-like changes in N-acetylaspartate and N-acetylaspartylglutamate in rat brain. Schizophr Res 2005; 73: 147-152.
    • (2005) Schizophr Res , vol.73 , pp. 147-152
    • Reynolds, L.M.1    Cochran, S.M.2    Morris, B.J.3    Pratt, J.A.4    Reynolds, G.P.5
  • 67
    • 24944566294 scopus 로고    scopus 로고
    • Central N-acetyl aspartylglutamate deficit: A possible pathogenesis of schizophrenia
    • Tsai SJ,. Central N-acetyl aspartylglutamate deficit: a possible pathogenesis of schizophrenia. Med Sci Monit 2005; 11: HY39-HY45.
    • (2005) Med Sci Monit , vol.11
    • Tsai, S.J.1
  • 69
    • 70350458181 scopus 로고    scopus 로고
    • Optimized glutamate detection at 3T
    • Hancu I,. Optimized glutamate detection at 3T. J Magn Reson Imaging 2009; 30: 1155-1162.
    • (2009) J Magn Reson Imaging , vol.30 , pp. 1155-1162
    • Hancu, I.1
  • 70
    • 53549083275 scopus 로고    scopus 로고
    • Comparative reliability of proton spectroscopy techniques designed to improve detection of J-coupled metabolites
    • Mullins PG, Chen H, Xu J, Caprihan A, Gasparovic C,. Comparative reliability of proton spectroscopy techniques designed to improve detection of J-coupled metabolites. Magn Reson Med 2008; 60: 964-969.
    • (2008) Magn Reson Med , vol.60 , pp. 964-969
    • Mullins, P.G.1    Chen, H.2    Xu, J.3    Caprihan, A.4    Gasparovic, C.5
  • 71
    • 0036522961 scopus 로고    scopus 로고
    • Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: Elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism
    • Lebon V, Petersen KF, Cline GW, et al. Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism. J Neurosci 2002; 22: 1523-1531.
    • (2002) J Neurosci , vol.22 , pp. 1523-1531
    • Lebon, V.1    Petersen, K.F.2    Cline, G.W.3
  • 72
    • 79958839616 scopus 로고    scopus 로고
    • The case of the missing glutamine
    • Hancu I, Port J,. The case of the missing glutamine. NMR Biomed 2011; 24: 529-535.
    • (2011) NMR Biomed , vol.24 , pp. 529-535
    • Hancu, I.1    Port, J.2
  • 73
    • 0031466522 scopus 로고    scopus 로고
    • Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy
    • Bartha R, Williamson PC, Drost DJ, et al. Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy. Arch Gen Psychiatry 1997; 54: 959-965.
    • (1997) Arch Gen Psychiatry , vol.54 , pp. 959-965
    • Bartha, R.1    Williamson, P.C.2    Drost, D.J.3
  • 74
    • 71849110853 scopus 로고    scopus 로고
    • Specific metabolites in the medial prefrontal cortex are associated with the neurocognitive deficits in schizophrenia: A preliminary study
    • Shirayama Y, Obata T, Matsuzawa D, et al. Specific metabolites in the medial prefrontal cortex are associated with the neurocognitive deficits in schizophrenia: a preliminary study. Neuroimage 2010; 49: 2783-2790.
    • (2010) Neuroimage , vol.49 , pp. 2783-2790
    • Shirayama, Y.1    Obata, T.2    Matsuzawa, D.3
  • 76
    • 10744228692 scopus 로고    scopus 로고
    • Ultrahigh field magnetic resonance imaging and spectroscopy
    • Ugurbil K, Adriany G, Andersen P, et al. Ultrahigh field magnetic resonance imaging and spectroscopy. Magn Reson Imaging 2003; 21: 1263-1281.
    • (2003) Magn Reson Imaging , vol.21 , pp. 1263-1281
    • Ugurbil, K.1    Adriany, G.2    Andersen, P.3
  • 77
    • 0032851967 scopus 로고    scopus 로고
    • Chandelier cells and epilepsy
    • DeFelipe J,. Chandelier cells and epilepsy. Brain 1999; 122 (Pt 10): 1807-1822.
    • (1999) Brain , vol.122 , Issue.PART 10 , pp. 1807-1822
    • Defelipe, J.1
  • 78
    • 0031017590 scopus 로고    scopus 로고
    • Regulation of excitatory input to inhibitory interneurons of the dentate gyrus during hypoxia
    • Doherty J, Dingledine R,. Regulation of excitatory input to inhibitory interneurons of the dentate gyrus during hypoxia. J Neurophysiol 1997; 77: 393-404.
    • (1997) J Neurophysiol , vol.77 , pp. 393-404
    • Doherty, J.1    Dingledine, R.2
  • 79
    • 34249789869 scopus 로고    scopus 로고
    • Control of brain glutamine synthesis by NMDA receptors
    • Rodrigo R, Felipo V,. Control of brain glutamine synthesis by NMDA receptors. Front Biosci 2007; 12: 883-890.
    • (2007) Front Biosci , vol.12 , pp. 883-890
    • Rodrigo, R.1    Felipo, V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.