Role of phase behavior in micronization of lysozyme via a supercritical anti-solvent process

Chemical Engineering Journal

Volumn 139, Issue 2, 2008, Pages 416-425

  Chang, Shan Chun ^a   Lee, Ming Jer ^a   Lin, Ho Mu ^a  

^a NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Lysozyme; Micronization process; Phase behavior; Supercritical anti solvent

Indexed keywords

AMORPHOUS MATERIALS; PHASE BEHAVIOR; PRECIPITATION (CHEMICAL); SUPERCRITICAL FLUIDS;

MICRONIZATION PROCESS; SUPERCRITICAL ANTI-SOLVENT;

ENZYMES;

AMORPHOUS MATERIALS; ENZYMES; PHASE BEHAVIOR; PRECIPITATION (CHEMICAL); SUPERCRITICAL FLUIDS;

EID: 42749095540     PISSN: 13858947     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cej.2007.12.008     Document Type: Article

References (35)

1. Manning M.C., Patel K., and Borchardt R.T. Stability of protein pharmaceuticals. Pharm. Res. 6 (1989) 903-918
2. 2-assisted aerosolization. J. Pharm. Sci. 90 (2001) 785-797
3. Matson D.W., Fulton J.L., Peterson R.C., and Smith R.D. Rapid expansion of supercritical fluid solutions: solute formation of powders, thin films, and fibers. Ind. Eng. Chem. Res. 26 (1987) 2298-2306
4. Rodrigues M., Peiriço N., Matos H., Gomes de Azevedo E., Lobato M.R., and Almeida A.J. Microcomposites theophylline/hydrogenated palm oil from a PGSS process for controlled drug delivery systems. J. Supercrit. Fluids 29 (2004) 175-184
5. Dixon D.J., Johnston K.P., and Bodmeier R.A. Polymeric materials formed by precipitation with a compressed fluid anti-solvent. AIChE J. 39 (1993) 127-139
6. Reverchon E. Supercritical-assisted atomization to produce micro- and/or nanoparticles of controlled size and distribution. Ind. Eng. Chem. Res. 41 (2002) 2405-2411
7. R.E. Sievers, S.P. Sellers, J.F. Carpenter, Supercritical fluid-assisted nebulization and bubble drying, World International Property Organization WO0075281 (2000).
8. Jung J., and Perrut M. Particle design using supercritical fluids: literature and patent survey. J. Supercrit. Fluids 20 (2001) 179-219
9. Vemavarapu C., Mollan M.J., Lodaya M., and Needham T.E. Design and process aspects of laboratory scale SCF particle formation systems. Int. J. Pharm. 292 (2005) 1-16
10. Reverchon E., and Adami R. Nanomaterials and supercritical fluids. J. Supercrit. Fluids 37 (2006) 1-22
11. Patton J.S., Trinchero P., and Platz R.M. Bioavailability of pulmonary delivered peptides and proteins: α-interferon, calcitonins and parathyroid hormones. J. Control. Release 28 (1994) 79-85
12. Adjei A., and Garren J. Pulmonary delivery of peptide drugs: effects of particles size on bioavailability of leuprolide acetate in healthy human male volunteers. Pharm. Res. 7 (1990) 565-569
13. Lai M.C., and Topp E.M. Solid-state chemical stability of proteins and peptides. J. Pharm. Sci. 88 (1999) 489-500
14. Yeo S.D., Lim G.B., Debenedetti P.G., and Bernstein H. Formation of microparticulate protein powders using a supercritical fluid antisolvent. Biotechnol. Bioeng. 41 (1993) 341-346
15. Chattopadhyay P., and Gupta R.B. Protein nanoparticles formation by supercritical antisolvent with enhanced mass transfer. AIChE J. 48 (2002) 235-244
16. Bustami R.T., Chan H.K., Dehghani F., and Foster N.R. Generation of micro-particles of proteins for aerosol delivery using high pressure modified carbon dioxide. Pharm. Res. 17 (2000) 1360-1366
17. Muhrer G., and Mazzotti M. Precipitation of lysozyme nanoparticles from dimethyl sulfoxide using carbon dioxide as antisolvent. Biotechnol. Prog. 19 (2003) 549-556
18. Jovanović N., Bouchard A., Hofland G.W., Witkamp G.J., Crommelin D.J.A., and Jiskoot W. Stabilization of proteins in dry powder formulations using supercritical fluid technology. Pharm. Res. 21 (2004) 1955-1969
19. Winters M.A., Knutson B.L., Debenedetti P.G., Sparks H.G., Przybycien T.M., Stevenson C.L., and Prestrelski S.J. Precipitation of proteins in supercritical carbon dioxide. J. Pharm. Sci. 85 (1996) 586-594
20. Moshashaee S., Bisrat M., Forbes R.T., Nyqvist H., and York P. Supercritical fluid processing of proteins. I. Lysozyme precipitation from organic solution. Eur. J. Pharm. Sci. 11 (2000) 239-245
21. Moshashaee S., Bisrat M., Forbes R.T., Quinn E.A., Nyqvist H., and York P. Supercritical fluid processing of proteins: lysozyme precipitation from aqueous solution. J. Pharm. Pharmacol. 55 (2003) 185-192
22. Reverchon E., Caputo G., and De Marco I. Role of phase behavior and atomization in the supercritical antisolvent precipitation. Ind. Eng. Chem. Res. 42 (2003) 6406-6414
23. Reverchon E. Micro and nano particles produced by supercritical fluids assisted techniques: present status and future developments. Chem. Eng. Trans. 2 (2002) 1-10
24. Chang S.C., Lee M.J., and Lin H.M. Nanoparticles formation for metallocene catalyzed cyclic olefin copolymer via a continuous supercritical anti-solvent process. J. Supercrit. Fluids 40 (2007) 420-432
25. Gallagher P.M., Coffey M.P., Krukonis V.J., and Klasutis N. Gas antisolvent recrystallization: new process to recrystallize compounds insoluble in supercritical fluids. ACS Symp. Ser. 406 (1989) 334-354
26. Chiu H.Y., Jung R.F., Lee M.J., and Lin H.M. Vapor-liquid phase equilibrium behavior of mixtures containing supercritical carbon dioxide near critical region. J. Supercrit. Fluids 44 (2008) 273-278
27. Gonzalez A.V., Tufeu R., and Subra P. High-pressure vapor-liquid equilibrium for binary systems carbon dioxide + dimethyl sulfoxide and carbon dioxide + dichloromethane. J. Chem. Eng. Data 47 (2002) 492-495
28. Schmitt W.J., Salada M.C., Shook G.G., and Speaker III S.M. Finely-divided powders by carrier solution injection into a near or supercritical fluid. AIChE J. 41 (1995) 2476-2486
29. Wu H.T., Lee M.J., and Lin H.M. Ultra-fine particles formation of C.I. pigment green 36 in different phase regions via a supercritical anti-solvent process. Dyes Pigments 75 (2007) 328-334
30. Dukhin S.S., Zhu C., Dave R., Pfeffer R., Luo J.J., Chavez F., and Shen Y. Dynamic interfacial tension near critical point of a solvent-antisolvent mixture and laminar jet stabilization. Colloids Surf. A 229 (2003) 181-199
31. He W.Z., Suo Q.L., Jiang Z.H., and Hong S.A.H.L. Precipitation of ephedrine by SEDS process using a specially design prefilming atomizer. J. Supercrit. Fluids 31 (2004) 101-110
32. Wu H.T., Lee M.J., and Lin H.M. Nano-particles formation for pigment red 177 via a continuous supercritical anti-solvent process. J. Supercrit. Fluids 33 (2005) 173-182
33. Chang S.C., Lee M.J., and Lin H.M. The influence of phase behavior on the morphology of protein α-chymotrypsin prepared via a supercritical anti-solvent process. Proceedings of the Eighth International Symposium on Supercritical Fluids. Kyoto, Japan, November 5-8 (2006)
34. Chang S.C., Lee M.J., and Lin H.M. The influence of phase behavior on the morphology of protein α-chymotrypsin prepared via a supercritical anti-solvent process. J. Supercrit. Fluids 44 (2008) 219-229
35. Bouchard A., Jovanović N., Jiskoot W., Mendes E., Witkamp G.J., Daan J.A., Crommelin J.A., and Hofland G.W. Lysozyme particle formation during supercritical fluid drying: particle morphology and molecular integrity. J. Supercrit. Fluids 40 (2007) 293-307