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Volumn 203, Issue 1, 2012, Pages 19-27

Characterization of [ 3H]CFT binding to the norepinephrine transporter suggests that binding of CFT and nisoxetine is not mutually exclusive

Author keywords

Binding; CFT; Dixon plot; Dopamine transporter; Mutually exclusive; Nisoxetine; Norepinephrine transporter

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; COCAINE; DESIPRAMINE; DOPAMINE; DOPAMINE TRANSPORTER; MAZINDOL; NISOXETINE; NORADRENALIN; NORADRENALIN TRANSPORTER; SODIUM;

EID: 81555219221     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2011.08.044     Document Type: Article
Times cited : (8)

References (38)
  • 1
    • 0024478380 scopus 로고
    • 3H]desipramine binding to rat brain tissue: binding to both noradrenaline uptake sites and sites not related to noradrenaline neurons
    • 3H]desipramine binding to rat brain tissue: binding to both noradrenaline uptake sites and sites not related to noradrenaline neurons. J. Neurochem. 1989, 52:1099-1106.
    • (1989) J. Neurochem. , vol.52 , pp. 1099-1106
    • Backstrom, I.T.1    Ross, S.B.2    Marcusson, J.O.3
  • 4
    • 0242491084 scopus 로고    scopus 로고
    • Interactions of cations and anions with the binding of uptake blockers to the dopamine transporter
    • Bonnet J. Interactions of cations and anions with the binding of uptake blockers to the dopamine transporter. Eur. J. Pharm. 2003, 479:199-212.
    • (2003) Eur. J. Pharm. , vol.479 , pp. 199-212
    • Bonnet, J.1
  • 5
    • 33847159529 scopus 로고    scopus 로고
    • The norepinephrine transporter in physiology and disease
    • Bönisch H., Brüss M. The norepinephrine transporter in physiology and disease. Handb. Exp. Pharmacol. 2006, 175:485-524.
    • (2006) Handb. Exp. Pharmacol. , vol.175 , pp. 485-524
    • Bönisch, H.1    Brüss, M.2
  • 6
    • 0141994011 scopus 로고    scopus 로고
    • Chi-Conopeptide MrIA partially overlaps desipramine and cocaine binding sites on the human norepinephrine transporter
    • Bryan-Lluka L.J., Bonisch H., Lewis R.J. chi-Conopeptide MrIA partially overlaps desipramine and cocaine binding sites on the human norepinephrine transporter. J. Biol. Chem. 2003, 278:40324-40329.
    • (2003) J. Biol. Chem. , vol.278 , pp. 40324-40329
    • Bryan-Lluka, L.J.1    Bonisch, H.2    Lewis, R.J.3
  • 7
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
    • Cheng Y., Prusoff W.H. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem. Pharmacol. 1973, 22:3099-3108.
    • (1973) Biochem. Pharmacol. , vol.22 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.H.2
  • 8
    • 0014617723 scopus 로고
    • Catecholamine uptake by synaptosomes in homogenates of rat brain: stereospecificity in different areas
    • Coyle J.T., Snyder S.H. Catecholamine uptake by synaptosomes in homogenates of rat brain: stereospecificity in different areas. J. Pharmacol. Exp. Ther. 1969, 170:221-231.
    • (1969) J. Pharmacol. Exp. Ther. , vol.170 , pp. 221-231
    • Coyle, J.T.1    Snyder, S.H.2
  • 10
    • 47549097343 scopus 로고    scopus 로고
    • D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action
    • Dutta A.K., Ghosh B., Biswas S., Reith M.E. D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action. Eur. J. Pharmacol. 2008, 589:73-79.
    • (2008) Eur. J. Pharmacol. , vol.589 , pp. 73-79
    • Dutta, A.K.1    Ghosh, B.2    Biswas, S.3    Reith, M.E.4
  • 11
    • 0032927199 scopus 로고    scopus 로고
    • Characteristics of drug interactions with recombinant biogenic amine transporters expressed in the same cell type
    • Eshleman A.J., Carmolli M., Cumbay M., Martens C.R., Neve K.A., Janowsky A. Characteristics of drug interactions with recombinant biogenic amine transporters expressed in the same cell type. J. Pharmacol. Exp. Ther. 1999, 289:877-885.
    • (1999) J. Pharmacol. Exp. Ther. , vol.289 , pp. 877-885
    • Eshleman, A.J.1    Carmolli, M.2    Cumbay, M.3    Martens, C.R.4    Neve, K.A.5    Janowsky, A.6
  • 12
    • 0019732263 scopus 로고
    • 3H] desipramine binding in rat cerebral cortex
    • 3H] desipramine binding in rat cerebral cortex. Prog. Neuropsychopharmacol. 1981, 5:553-557.
    • (1981) Prog. Neuropsychopharmacol. , vol.5 , pp. 553-557
    • Hrdina, P.D.1
  • 13
    • 0021287012 scopus 로고
    • 3H]mazindol binding associated with neuronal dopamine and norepinephrine uptake sites
    • 3H]mazindol binding associated with neuronal dopamine and norepinephrine uptake sites. Mol. Pharmacol. 1984, 26:35-44.
    • (1984) Mol. Pharmacol. , vol.26 , pp. 35-44
    • Javitch, J.A.1    Blaustein, R.O.2    Snyder, S.H.3
  • 16
    • 0020336446 scopus 로고
    • 3H]desipramine binding associated with neuronal norepinephrine uptake sites in rat brain membranes
    • 3H]desipramine binding associated with neuronal norepinephrine uptake sites in rat brain membranes. J. Neurosci. 1982, 2:1515-1525.
    • (1982) J. Neurosci. , vol.2 , pp. 1515-1525
    • Lee, C.M.1    Javitch, J.A.2    Snyder, S.H.3
  • 17
    • 0032974887 scopus 로고    scopus 로고
    • 3H]WIN 35,428 to the human dopamine transporter
    • 3H]WIN 35,428 to the human dopamine transporter. J. Neurochem. 1999, 72:1095-1109.
    • (1999) J. Neurochem. , vol.72 , pp. 1095-1109
    • Li, L.B.1    Reith, M.E.2
  • 18
    • 0034023604 scopus 로고    scopus 로고
    • - with the binding of amphetamine, octopamine, and tyramine to the human dopamine transporter
    • - with the binding of amphetamine, octopamine, and tyramine to the human dopamine transporter. J. Neurochem. 2000, 74:1538-1552.
    • (2000) J. Neurochem. , vol.74 , pp. 1538-1552
    • Li, L.B.1    Reith, M.E.2
  • 19
    • 0942276396 scopus 로고    scopus 로고
    • Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding
    • Loland C.J., Granas C., Javitch J.A., Gether U. Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding. J. Biol. Chem. 2004, 279:3228-3238.
    • (2004) J. Biol. Chem. , vol.279 , pp. 3228-3238
    • Loland, C.J.1    Granas, C.2    Javitch, J.A.3    Gether, U.4
  • 21
    • 0032480011 scopus 로고    scopus 로고
    • Delineation of an endogenous zinc-binding site in the human dopamine transporter
    • Norregaard L., Frederiksen D., Nielsen E.O., Gether U. Delineation of an endogenous zinc-binding site in the human dopamine transporter. EMBO J. 1998, 17:4266-4273.
    • (1998) EMBO J. , vol.17 , pp. 4266-4273
    • Norregaard, L.1    Frederiksen, D.2    Nielsen, E.O.3    Gether, U.4
  • 22
    • 0026433037 scopus 로고
    • Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter
    • Pacholczyk T., Blakely R.D., Amara S.G. Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter. Nature 1991, 350:350-354.
    • (1991) Nature , vol.350 , pp. 350-354
    • Pacholczyk, T.1    Blakely, R.D.2    Amara, S.G.3
  • 23
    • 34547093872 scopus 로고    scopus 로고
    • Chi-Conotoxin and tricyclic antidepressant interactions at the norepinephrine transporter define a new transporter model
    • Paczkowski F.A., Sharpe I.A., Dutertre S., Lewis R.J. chi-Conotoxin and tricyclic antidepressant interactions at the norepinephrine transporter define a new transporter model. J. Biol. Chem. 2007, 282:17837-17844.
    • (2007) J. Biol. Chem. , vol.282 , pp. 17837-17844
    • Paczkowski, F.A.1    Sharpe, I.A.2    Dutertre, S.3    Lewis, R.J.4
  • 24
    • 68949176654 scopus 로고    scopus 로고
    • Structure and localisation of drug binding sites on neurotransmitter transporters
    • Ravna A.W., Sylte I., Dahl S.G. Structure and localisation of drug binding sites on neurotransmitter transporters. J. Mol. Model. 2009, 15(10):1155-1164.
    • (2009) J. Mol. Model. , vol.15 , Issue.10 , pp. 1155-1164
    • Ravna, A.W.1    Sylte, I.2    Dahl, S.G.3
  • 25
    • 14844311962 scopus 로고    scopus 로고
    • Pharmacological profile of radioligand binding to the norepinephrine transporter: instances of poor indication of functional activity
    • Reith M.E.A., Wang L.C., Dutta A.K. Pharmacological profile of radioligand binding to the norepinephrine transporter: instances of poor indication of functional activity. J. Neurosci. Methods 2005, 143:87-94.
    • (2005) J. Neurosci. Methods , vol.143 , pp. 87-94
    • Reith, M.E.A.1    Wang, L.C.2    Dutta, A.K.3
  • 27
    • 78649920349 scopus 로고    scopus 로고
    • The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter
    • Sarker S., Weissensteiner R., Steiner I., Sitte H.H., Ecker G.F., Freissmuth M., Sucic S. The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter. Mol. Pharmacol. 2010, 78:1026-1035.
    • (2010) Mol. Pharmacol. , vol.78 , pp. 1026-1035
    • Sarker, S.1    Weissensteiner, R.2    Steiner, I.3    Sitte, H.H.4    Ecker, G.F.5    Freissmuth, M.6    Sucic, S.7
  • 29
    • 54349096623 scopus 로고    scopus 로고
    • Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties
    • Schmitt K.C., Zhen J., Kharkar P., Mishra M., Chen N., Dutta A.K., Reith M.E. Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties. J. Neurochem. 2008, 107:928-940.
    • (2008) J. Neurochem. , vol.107 , pp. 928-940
    • Schmitt, K.C.1    Zhen, J.2    Kharkar, P.3    Mishra, M.4    Chen, N.5    Dutta, A.K.6    Reith, M.E.7
  • 32
    • 24944441653 scopus 로고    scopus 로고
    • Roles of transmembrane domain 2 and the first intracellular loop in human noradrenaline transporter function: pharmacological and SCAM analysis
    • Sucic S., Bryan-Lluka L.J. Roles of transmembrane domain 2 and the first intracellular loop in human noradrenaline transporter function: pharmacological and SCAM analysis. J. Neurochem. 2005, 94:1620-1630.
    • (2005) J. Neurochem. , vol.94 , pp. 1620-1630
    • Sucic, S.1    Bryan-Lluka, L.J.2
  • 33
    • 0026610297 scopus 로고
    • 3H]nisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding
    • 3H]nisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding. J. Pharmacol. Exp. Ther. 1992, 260:427-436.
    • (1992) J. Pharmacol. Exp. Ther. , vol.260 , pp. 427-436
    • Tejani-Butt, S.M.1
  • 34
    • 0023921625 scopus 로고
    • Potential misconceptions arising from the application of enzyme kinetic equations to ligand-receptor systems at equilibrium
    • Tomlinson G. Potential misconceptions arising from the application of enzyme kinetic equations to ligand-receptor systems at equilibrium. Can. J. Physiol. Pharmacol. 1988, 66:342-349.
    • (1988) Can. J. Physiol. Pharmacol. , vol.66 , pp. 342-349
    • Tomlinson, G.1
  • 35
    • 0034628495 scopus 로고    scopus 로고
    • Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationships, and behavioral pharmacological studies
    • Wang S., Sakamuri S., Enyedy I.J., Kozikowski A.P., Deschaux O., Bandyopadhyay B.C., Tella S.R., Zaman W.A., Johnson K.M. Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationships, and behavioral pharmacological studies. J. Med. Chem. 2000, 43:351-360.
    • (2000) J. Med. Chem. , vol.43 , pp. 351-360
    • Wang, S.1    Sakamuri, S.2    Enyedy, I.J.3    Kozikowski, A.P.4    Deschaux, O.5    Bandyopadhyay, B.C.6    Tella, S.R.7    Zaman, W.A.8    Johnson, K.M.9
  • 36
    • 26944446958 scopus 로고    scopus 로고
    • + gradient and membrane potential: dopamine versus other substrates
    • + gradient and membrane potential: dopamine versus other substrates. Neuropharmacology 2005, 49:769-779.
    • (2005) Neuropharmacology , vol.49 , pp. 769-779
    • Zhen, J.1    Chen, N.2    Reith, M.E.A.3
  • 37
    • 67349282342 scopus 로고    scopus 로고
    • Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures
    • Zhou Z., Zhen J., Karpowich N.K., Law C.J., Reith M.E., Wang D.N. Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures. Nat. Struct. Mol. Biol. 2009, 16:652-657.
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 652-657
    • Zhou, Z.1    Zhen, J.2    Karpowich, N.K.3    Law, C.J.4    Reith, M.E.5    Wang, D.N.6
  • 38
    • 1242269210 scopus 로고    scopus 로고
    • The persistent membrane retention of desipramine causes lasting inhibition of norepinephrine transporter function
    • Zhu M.Y., Kyle P.B., Hume A.S., Ordway G.A. The persistent membrane retention of desipramine causes lasting inhibition of norepinephrine transporter function. Neurochem. Res. 2004, 29:419-427.
    • (2004) Neurochem. Res. , vol.29 , pp. 419-427
    • Zhu, M.Y.1    Kyle, P.B.2    Hume, A.S.3    Ordway, G.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.