메뉴 건너뛰기




Volumn 59, Issue 5, 2011, Pages 807-821

Gastrointestinal stromal tumours-an update for histopathologists

Author keywords

BRAF; Carney syndrome; CD117; DOG1; Gastrointestinal stromal tumour; Imatinib; Insulin growth factor 1 receptor; KIT; Paediatric; PDGFRA; Prognosis; Succinate dehydrogenase; Sunitinib

Indexed keywords

B RAF KINASE; CARBONATE DEHYDRATASE II; DASATINIB; DOG1 PROTEIN; ESTROGEN RECEPTOR ALPHA; FLUORODEOXYGLUCOSE F 18; HEAT SHOCK PROTEIN; IMATINIB; NESTIN; NILOTINIB; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN; PROTEIN KINASE C THETA; SOMATOMEDIN BINDING PROTEIN 1; STEM CELL FACTOR RECEPTOR; SUCCINATE DEHYDROGENASE; SUNITINIB; UNCLASSIFIED DRUG; VEMURAFENIB;

EID: 81555216746     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2011.03812.x     Document Type: Review
Times cited : (47)

References (94)
  • 1
    • 13444270334 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era-a population-based study in western Sweden
    • Nilsson B, Bumming P, Meis-Kindblom JM et al. Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era-a population-based study in western Sweden. Cancer 2005; 103; 821-829.
    • (2005) Cancer , vol.103 , pp. 821-829
    • Nilsson, B.1    Bumming, P.2    Meis-Kindblom, J.M.3
  • 2
    • 25444448316 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors in Iceland, 1990-2003: the Icelandic GIST study, a population-based incidence and pathologic risk stratification study
    • Tryggvason G, Gislason HG, Magnusson MK, Jonasson JG. Gastrointestinal stromal tumors in Iceland, 1990-2003: the Icelandic GIST study, a population-based incidence and pathologic risk stratification study. Int. J. Cancer 2005; 117; 289-293.
    • (2005) Int. J. Cancer , vol.117 , pp. 289-293
    • Tryggvason, G.1    Gislason, H.G.2    Magnusson, M.K.3    Jonasson, J.G.4
  • 3
    • 0036301722 scopus 로고    scopus 로고
    • Diagnosis of gastrointestinal stromal tumors: a consensus approach
    • Fletcher CD, Berman JJ, Corless C et al. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum. Pathol. 2002; 33; 459-465.
    • (2002) Hum. Pathol. , vol.33 , pp. 459-465
    • Fletcher, C.D.1    Berman, J.J.2    Corless, C.3
  • 4
    • 49749122255 scopus 로고    scopus 로고
    • Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours
    • Lasota J, Miettinen M. Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours. Histopathology 2008; 53; 245-266.
    • (2008) Histopathology , vol.53 , pp. 245-266
    • Lasota, J.1    Miettinen, M.2
  • 5
    • 44449178477 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: key to diagnosis and choice of therapy
    • Rutkowski P, Debiec-Rychter M, Ruka W. Gastrointestinal stromal tumors: key to diagnosis and choice of therapy. Mol. Diagn. Ther. 2008; 12; 131-143.
    • (2008) Mol. Diagn. Ther. , vol.12 , pp. 131-143
    • Rutkowski, P.1    Debiec-Rychter, M.2    Ruka, W.3
  • 6
    • 81555211859 scopus 로고    scopus 로고
    • NHS National Institute for Clinical Excellence. Imatinib for the treatment of unresectable and/or metastatic gastrointestinal stromal tumours. Technology Appraisal 86, October. Available at: (accessed 2 December 2010)
    • NHS National Institute for Clinical Excellence. Imatinib for the treatment of unresectable and/or metastatic gastrointestinal stromal tumours. Technology Appraisal 86, October 2004. Available at: (accessed 2 December 2010).
    • (2004)
  • 7
    • 20944443259 scopus 로고    scopus 로고
    • Consensus meeting for the management of gastrointestinal stromal tumors. Report of the GIST Consensus Conference of 20-21 March 2004, under the auspices of ESMO
    • Blay JY, Bonvalot S, Casali P et al. Consensus meeting for the management of gastrointestinal stromal tumors. Report of the GIST Consensus Conference of 20-21 March 2004, under the auspices of ESMO. Ann. Oncol. 2005; 16; 566-578.
    • (2005) Ann. Oncol. , vol.16 , pp. 566-578
    • Blay, J.Y.1    Bonvalot, S.2    Casali, P.3
  • 8
    • 64549158437 scopus 로고    scopus 로고
    • Antigen retrieval and primary antibody type affect sensitivity but not specificity of CD117 immunohistochemistry
    • Wong NA, Melegh Z. Antigen retrieval and primary antibody type affect sensitivity but not specificity of CD117 immunohistochemistry. Histopathology 2009; 54; 529-538.
    • (2009) Histopathology , vol.54 , pp. 529-538
    • Wong, N.A.1    Melegh, Z.2
  • 9
    • 0035101531 scopus 로고    scopus 로고
    • Expression of the intermediate filament nestin in gastrointestinal stromal tumors and interstitial cells of Cajal
    • Tsujimura T, Makiishi-Shimobayashi C, Lundkvist J et al. Expression of the intermediate filament nestin in gastrointestinal stromal tumors and interstitial cells of Cajal. Am. J. Pathol. 2001; 158; 817-823.
    • (2001) Am. J. Pathol. , vol.158 , pp. 817-823
    • Tsujimura, T.1    Makiishi-Shimobayashi, C.2    Lundkvist, J.3
  • 10
    • 77952009344 scopus 로고    scopus 로고
    • Carbonic anhydrase II. A novel biomarker for gastrointestinal stromal tumors
    • Parkkila S, Lasota J, Fletcher JA et al. Carbonic anhydrase II. A novel biomarker for gastrointestinal stromal tumors. Mod. Pathol. 2010; 23; 743-750.
    • (2010) Mod. Pathol. , vol.23 , pp. 743-750
    • Parkkila, S.1    Lasota, J.2    Fletcher, J.A.3
  • 11
    • 16444380600 scopus 로고    scopus 로고
    • PKC theta, a novel immunohistochemical marker for gastrointestinal stromal tumors (GIST), especially useful for identifying KIT-negative tumors
    • Motegi A, Sakurai S, Nakayama H, Sano T, Oyama T, Nakajima T. PKC theta, a novel immunohistochemical marker for gastrointestinal stromal tumors (GIST), especially useful for identifying KIT-negative tumors. Pathol. Int. 2005; 55; 106-112.
    • (2005) Pathol. Int. , vol.55 , pp. 106-112
    • Motegi, A.1    Sakurai, S.2    Nakayama, H.3    Sano, T.4    Oyama, T.5    Nakajima, T.6
  • 12
    • 62849083680 scopus 로고    scopus 로고
    • Monoclonal antibody DOG1.1 shows higher sensitivity than KIT in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes
    • Liegl B, Hornick JL, Corless CL, Fletcher CD. Monoclonal antibody DOG1.1 shows higher sensitivity than KIT in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes. Am. J. Surg. Pathol. 2009; 33; 437-446.
    • (2009) Am. J. Surg. Pathol. , vol.33 , pp. 437-446
    • Liegl, B.1    Hornick, J.L.2    Corless, C.L.3    Fletcher, C.D.4
  • 13
    • 38649098794 scopus 로고    scopus 로고
    • A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors
    • Espinosa I, Lee CH, Kim MK et al. A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors. Am. J. Surg. Pathol. 2008; 32; 210-218.
    • (2008) Am. J. Surg. Pathol. , vol.32 , pp. 210-218
    • Espinosa, I.1    Lee, C.H.2    Kim, M.K.3
  • 14
    • 0036337887 scopus 로고    scopus 로고
    • Patterns of nestin and other intermediate filament expression distinguish between gastrointestinal stromal tumors, leiomyomas and schwannomas
    • Sarlomo-Rikala M, Tsujimura T, Lendahl U, Miettinen M. Patterns of nestin and other intermediate filament expression distinguish between gastrointestinal stromal tumors, leiomyomas and schwannomas. APMIS 2002; 110; 499-507.
    • (2002) APMIS , vol.110 , pp. 499-507
    • Sarlomo-Rikala, M.1    Tsujimura, T.2    Lendahl, U.3    Miettinen, M.4
  • 15
    • 77955817308 scopus 로고    scopus 로고
    • DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours
    • Novelli M, Rossi S, Rodriguez-Justo M et al. DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours. Histopathology 2010; 57; 259-270.
    • (2010) Histopathology , vol.57 , pp. 259-270
    • Novelli, M.1    Rossi, S.2    Rodriguez-Justo, M.3
  • 16
    • 77955816314 scopus 로고    scopus 로고
    • Specificity of DOG1 (K9 clone) and protein kinase C theta (clone 27) as immunohistochemical markers of gastrointestinal stromal tumour
    • Wong NA, Shelley-Fraser G. Specificity of DOG1 (K9 clone) and protein kinase C theta (clone 27) as immunohistochemical markers of gastrointestinal stromal tumour. Histopathology 2010; 57; 250-258.
    • (2010) Histopathology , vol.57 , pp. 250-258
    • Wong, N.A.1    Shelley-Fraser, G.2
  • 17
    • 70249090434 scopus 로고    scopus 로고
    • DOG1 antibody in the differential diagnosis of gastrointestinal stromal tumors: a study of 1840 cases
    • Miettinen M, Wang ZF, Lasota J. DOG1 antibody in the differential diagnosis of gastrointestinal stromal tumors: a study of 1840 cases. Am. J. Surg. Pathol. 2009; 33; 1401-1408.
    • (2009) Am. J. Surg. Pathol. , vol.33 , pp. 1401-1408
    • Miettinen, M.1    Wang, Z.F.2    Lasota, J.3
  • 19
    • 3042594995 scopus 로고    scopus 로고
    • The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status
    • West RB, Corless CL, Chen X et al. The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status. Am. J. Pathol. 2004; 165; 107-113.
    • (2004) Am. J. Pathol. , vol.165 , pp. 107-113
    • West, R.B.1    Corless, C.L.2    Chen, X.3
  • 21
    • 37749036850 scopus 로고    scopus 로고
    • Analysis of c-kit protein expression in pancreatic neoplasms and its implication for prognosis
    • Kimura W, Ma J, Takeshita A et al. Analysis of c-kit protein expression in pancreatic neoplasms and its implication for prognosis. Hepatogastroenterology 2007; 54; 2203-2208.
    • (2007) Hepatogastroenterology , vol.54 , pp. 2203-2208
    • Kimura, W.1    Ma, J.2    Takeshita, A.3
  • 22
    • 34250805986 scopus 로고    scopus 로고
    • A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation
    • Preto A, Moutinho C, Velho S et al. A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation. Virchows Arch. 2007; 450; 619-626.
    • (2007) Virchows Arch. , vol.450 , pp. 619-626
    • Preto, A.1    Moutinho, C.2    Velho, S.3
  • 23
    • 33745099617 scopus 로고    scopus 로고
    • An update on molecular genetics of gastrointestinal stromal tumours
    • Tornillo L, Terracciano LM. An update on molecular genetics of gastrointestinal stromal tumours. J. Clin. Pathol. 2006; 59; 557-563.
    • (2006) J. Clin. Pathol. , vol.59 , pp. 557-563
    • Tornillo, L.1    Terracciano, L.M.2
  • 24
    • 68849120567 scopus 로고    scopus 로고
    • KRAS mutation testing in colorectal cancer
    • Plesec TP, Hunt JL. KRAS mutation testing in colorectal cancer. Adv. Anat. Pathol. 2009; 16; 196-203.
    • (2009) Adv. Anat. Pathol. , vol.16 , pp. 196-203
    • Plesec, T.P.1    Hunt, J.L.2
  • 25
    • 10744225271 scopus 로고    scopus 로고
    • Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors
    • Antonescu CR, Sommer G, Sarran L et al. Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors. Clin. Cancer Res. 2003; 9; 3329-3337.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 3329-3337
    • Antonescu, C.R.1    Sommer, G.2    Sarran, L.3
  • 26
    • 33646685694 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors of the jejunum and ileum: a clinicopathologic, immunohistochemical, and molecular genetic study of 906 cases before imatinib with long-term follow-up
    • Miettinen M, Makhlouf H, Sobin LH, Lasota J. Gastrointestinal stromal tumors of the jejunum and ileum: a clinicopathologic, immunohistochemical, and molecular genetic study of 906 cases before imatinib with long-term follow-up. Am. J. Surg. Pathol. 2006; 30; 477-489.
    • (2006) Am. J. Surg. Pathol. , vol.30 , pp. 477-489
    • Miettinen, M.1    Makhlouf, H.2    Sobin, L.H.3    Lasota, J.4
  • 27
    • 14344256167 scopus 로고    scopus 로고
    • PDGFRalpha- and c-kit-mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features
    • Pauls K, Merkelbach-Bruse S, Thal D, Buttner R, Wardelmann E. PDGFRalpha- and c-kit-mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features. Histopathology 2005; 46; 166-175.
    • (2005) Histopathology , vol.46 , pp. 166-175
    • Pauls, K.1    Merkelbach-Bruse, S.2    Thal, D.3    Buttner, R.4    Wardelmann, E.5
  • 28
    • 68249086826 scopus 로고    scopus 로고
    • Gain-of-function PDGFRA mutations, earlier reported in gastrointestinal stromal tumors, are common in small intestinal inflammatory fibroid polyps. A study of 60 cases
    • Lasota J, Wang ZF, Sobin LH, Miettinen M. Gain-of-function PDGFRA mutations, earlier reported in gastrointestinal stromal tumors, are common in small intestinal inflammatory fibroid polyps. A study of 60 cases. Mod. Pathol. 2009; 22; 1049-1056.
    • (2009) Mod. Pathol. , vol.22 , pp. 1049-1056
    • Lasota, J.1    Wang, Z.F.2    Sobin, L.H.3    Miettinen, M.4
  • 29
    • 53149140625 scopus 로고    scopus 로고
    • Inflammatory fibroid polyps harbour mutations in the platelet-derived growth factor receptor alpha (PDGFRA) gene
    • Schildhaus HU, Cavlar T, Binot E, Buttner R, Wardelmann E, Merkelbach-Bruse S. Inflammatory fibroid polyps harbour mutations in the platelet-derived growth factor receptor alpha (PDGFRA) gene. J. Pathol. 2008; 216; 176-182.
    • (2008) J. Pathol. , vol.216 , pp. 176-182
    • Schildhaus, H.U.1    Cavlar, T.2    Binot, E.3    Buttner, R.4    Wardelmann, E.5    Merkelbach-Bruse, S.6
  • 30
  • 31
    • 33750618188 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: pathology and prognosis at different sites
    • Miettinen M, Lasota J. Gastrointestinal stromal tumors: pathology and prognosis at different sites. Semin. Diagn. Pathol. 2006; 23; 70-83.
    • (2006) Semin. Diagn. Pathol. , vol.23 , pp. 70-83
    • Miettinen, M.1    Lasota, J.2
  • 32
    • 49649119001 scopus 로고    scopus 로고
    • Molecular characterization of pediatric gastrointestinal stromal tumors
    • Agaram NP, Laquaglia MP, Ustun B et al. Molecular characterization of pediatric gastrointestinal stromal tumors. Clin. Cancer Res. 2008; 14; 3204-3215.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 3204-3215
    • Agaram, N.P.1    Laquaglia, M.P.2    Ustun, B.3
  • 33
    • 73949152219 scopus 로고    scopus 로고
    • Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: findings in 104 cases
    • Zhang L, Smyrk TC, Young WF Jr, Stratakis CA, Carney JA. Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: findings in 104 cases. Am. J. Surg. Pathol. 2010; 34; 53-64.
    • (2010) Am. J. Surg. Pathol. , vol.34 , pp. 53-64
    • Zhang, L.1    Smyrk, T.C.2    Young Jr., W.F.3    Stratakis, C.A.4    Carney, J.A.5
  • 34
    • 48149093474 scopus 로고    scopus 로고
    • Which is the optimal risk stratification system for surgically treated localized primary GIST? Comparison of three contemporary prognostic criteria in 171 tumors and a proposal for a modified Armed Forces Institute of Pathology risk criteria
    • Goh BK, Chow PK, Yap WM et al. Which is the optimal risk stratification system for surgically treated localized primary GIST? Comparison of three contemporary prognostic criteria in 171 tumors and a proposal for a modified Armed Forces Institute of Pathology risk criteria. Ann. Surg. Oncol. 2008; 15; 2153-2163.
    • (2008) Ann. Surg. Oncol. , vol.15 , pp. 2153-2163
    • Goh, B.K.1    Chow, P.K.2    Yap, W.M.3
  • 35
    • 50649085726 scopus 로고    scopus 로고
    • Risk stratification of patients diagnosed with gastrointestinal stromal tumor
    • Joensuu H. Risk stratification of patients diagnosed with gastrointestinal stromal tumor. Hum. Pathol. 2008; 39; 1411-1419.
    • (2008) Hum. Pathol. , vol.39 , pp. 1411-1419
    • Joensuu, H.1
  • 36
    • 71449088757 scopus 로고    scopus 로고
    • Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumour: a retrospective analysis
    • Gold JS, Gonen M, Gutierrez A et al. Development and validation of a prognostic nomogram for recurrence-free survival after complete surgical resection of localised primary gastrointestinal stromal tumour: a retrospective analysis. Lancet Oncol. 2009; 10; 1045-1052.
    • (2009) Lancet Oncol. , vol.10 , pp. 1045-1052
    • Gold, J.S.1    Gonen, M.2    Gutierrez, A.3
  • 37
    • 81555211855 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumour (GIST)
    • Sobin L, Gospodarowicz M, Wittekind C eds., 7th edn. Oxford: Wiley-Blackwell
    • Gastrointestinal stromal tumour (GIST). In Sobin L, Gospodarowicz M, Wittekind C eds. TNM classification of malignant tumour, 7th edn. Oxford: Wiley-Blackwell, 2010; 78-81.
    • (2010) TNM classification of malignant tumour , pp. 78-81
  • 38
    • 0037103424 scopus 로고    scopus 로고
    • Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
    • Demetri GD, von MM, Blanke CD et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N. Engl. J. Med. 2002; 347; 472-480.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 472-480
    • Demetri, G.D.1    von, M.M.2    Blanke, C.D.3
  • 39
    • 20844433223 scopus 로고    scopus 로고
    • Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial
    • Verweij J, Casali PG, Zalcberg J et al. Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial. Lancet 2004; 364; 1127-1134.
    • (2004) Lancet , vol.364 , pp. 1127-1134
    • Verweij, J.1    Casali, P.G.2    Zalcberg, J.3
  • 40
    • 24944529613 scopus 로고    scopus 로고
    • Initial and late resistance to imatinib in advanced gastrointestinal stromal tumors are predicted by different prognostic factors: a European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trials Group study
    • Van Glabbeke M, Verweij J, Casali PG et al. Initial and late resistance to imatinib in advanced gastrointestinal stromal tumors are predicted by different prognostic factors: a European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trials Group study. J. Clin. Oncol. 2005; 23; 5795-5804.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 5795-5804
    • Van Glabbeke, M.1    Verweij, J.2    Casali, P.G.3
  • 41
    • 56749098278 scopus 로고    scopus 로고
    • Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor
    • Heinrich MC, Maki RG, Corless CL et al. Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor. J. Clin. Oncol. 2008; 26; 5352-5359.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 5352-5359
    • Heinrich, M.C.1    Maki, R.G.2    Corless, C.L.3
  • 42
    • 68949174991 scopus 로고    scopus 로고
    • Nilotinib in the treatment of advanced gastrointestinal stromal tumours resistant to both imatinib and sunitinib
    • Montemurro M, Schoffski P, Reichardt P et al. Nilotinib in the treatment of advanced gastrointestinal stromal tumours resistant to both imatinib and sunitinib. Eur. J. Cancer 2009; 45; 2293-2297.
    • (2009) Eur. J. Cancer , vol.45 , pp. 2293-2297
    • Montemurro, M.1    Schoffski, P.2    Reichardt, P.3
  • 43
    • 53249152139 scopus 로고    scopus 로고
    • Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation
    • Dewaele B, Wasag B, Cools J et al. Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation. Clin. Cancer Res. 2008; 14; 5749-5758.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 5749-5758
    • Dewaele, B.1    Wasag, B.2    Cools, J.3
  • 44
    • 62849096370 scopus 로고    scopus 로고
    • Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial
    • DeMatteo RP, Ballman KV, Antonescu CR et al. Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial. Lancet 2009; 373; 1097-1104.
    • (2009) Lancet , vol.373 , pp. 1097-1104
    • DeMatteo, R.P.1    Ballman, K.V.2    Antonescu, C.R.3
  • 45
    • 33746401591 scopus 로고    scopus 로고
    • KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours
    • Debiec-Rychter M, Sciot R, Le CA et al. KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours. Eur. J. Cancer 2006; 42; 1093-1103.
    • (2006) Eur. J. Cancer , vol.42 , pp. 1093-1103
    • Debiec-Rychter, M.1    Sciot, R.2    Le, C.A.3
  • 46
    • 56749156604 scopus 로고    scopus 로고
    • Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal stromal tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group
    • Heinrich MC, Owzar K, Corless CL et al. Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal stromal tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group. J. Clin. Oncol. 2008; 26; 5360-5367.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 5360-5367
    • Heinrich, M.C.1    Owzar, K.2    Corless, C.L.3
  • 47
    • 33646432734 scopus 로고    scopus 로고
    • Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate
    • Prenen H, Cools J, Mentens N et al. Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate. Clin. Cancer Res. 2006; 12; 2622-2627.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 2622-2627
    • Prenen, H.1    Cools, J.2    Mentens, N.3
  • 48
    • 23944476156 scopus 로고    scopus 로고
    • PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib
    • Corless CL, Schroeder A, Griffith D et al. PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib. J. Clin. Oncol. 2005; 23; 5357-5364.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 5357-5364
    • Corless, C.L.1    Schroeder, A.2    Griffith, D.3
  • 49
    • 50249092801 scopus 로고    scopus 로고
    • Heterogeneity of kinase inhibitor resistance mechanisms in GIST
    • Liegl B, Kepten I, Le C et al. Heterogeneity of kinase inhibitor resistance mechanisms in GIST. J. Pathol. 2008; 216; 64-74.
    • (2008) J. Pathol. , vol.216 , pp. 64-74
    • Liegl, B.1    Kepten, I.2    Le, C.3
  • 50
    • 33645693156 scopus 로고    scopus 로고
    • Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate
    • Wardelmann E, Merkelbach-Bruse S, Pauls K et al. Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate. Clin. Cancer Res. 2006; 12; 1743-1749.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 1743-1749
    • Wardelmann, E.1    Merkelbach-Bruse, S.2    Pauls, K.3
  • 51
    • 0042978501 scopus 로고    scopus 로고
    • Neoadjuvant, adjuvant and palliative treatment of gastrointestinal stromal tumours (GIST) with imatinib: a centre-based study of 17 patients
    • Bumming P, Andersson J, Meis-Kindblom JM et al. Neoadjuvant, adjuvant and palliative treatment of gastrointestinal stromal tumours (GIST) with imatinib: a centre-based study of 17 patients. Br. J. Cancer 2003; 89; 460-464.
    • (2003) Br. J. Cancer , vol.89 , pp. 460-464
    • Bumming, P.1    Andersson, J.2    Meis-Kindblom, J.M.3
  • 52
    • 17144412186 scopus 로고    scopus 로고
    • Pathological changes related to Imatinib treatment in a patient with a metastatic gastrointestinal stromal tumour
    • Abdulkader I, Cameselle-Teijeiro J, Forteza J. Pathological changes related to Imatinib treatment in a patient with a metastatic gastrointestinal stromal tumour. Histopathology 2005; 46; 470-472.
    • (2005) Histopathology , vol.46 , pp. 470-472
    • Abdulkader, I.1    Cameselle-Teijeiro, J.2    Forteza, J.3
  • 53
    • 22144464484 scopus 로고    scopus 로고
    • Changing phenotype of gastrointestinal stromal tumours under imatinib mesylate treatment: a potential diagnostic pitfall
    • Pauwels P, Debiec-Rychter M, Stul M, De WI, van Oosterom AT, Sciot R. Changing phenotype of gastrointestinal stromal tumours under imatinib mesylate treatment: a potential diagnostic pitfall. Histopathology 2005; 47; 41-47.
    • (2005) Histopathology , vol.47 , pp. 41-47
    • Pauwels, P.1    Debiec-Rychter, M.2    Stul, M.3    De, W.I.4    van Oosterom, A.T.5    Sciot, R.6
  • 54
    • 47749134584 scopus 로고    scopus 로고
    • The lessons of GIST-PET and PET/CT: a new paradigm for imaging
    • Van den Abbeele AD. The lessons of GIST-PET and PET/CT: a new paradigm for imaging. Oncologist 2008; 13(Suppl. 2); 8-13.
    • (2008) Oncologist , vol.13 , Issue.SUPPL. 2 , pp. 8-13
    • Van den Abbeele, A.D.1
  • 55
    • 59649102913 scopus 로고    scopus 로고
    • Follow-up of hepatic and peritoneal metastases of gastrointestinal tumors (GIST) under imatinib therapy requires different criteria of radiological evaluation (size is not everything!)
    • Mabille M, Vanel D, Albiter M et al. Follow-up of hepatic and peritoneal metastases of gastrointestinal tumors (GIST) under imatinib therapy requires different criteria of radiological evaluation (size is not everything!). Eur. J. Radiol. 2009; 69; 204-208.
    • (2009) Eur. J. Radiol. , vol.69 , pp. 204-208
    • Mabille, M.1    Vanel, D.2    Albiter, M.3
  • 56
    • 60249088620 scopus 로고    scopus 로고
    • Rhabdomyosarcomatous differentiation in gastrointestinal stromal tumors after tyrosine kinase inhibitor therapy: a novel form of tumor progression
    • Liegl B, Hornick JL, Antonescu CR, Corless CL, Fletcher CD. Rhabdomyosarcomatous differentiation in gastrointestinal stromal tumors after tyrosine kinase inhibitor therapy: a novel form of tumor progression. Am. J. Surg. Pathol. 2009; 33; 218-226.
    • (2009) Am. J. Surg. Pathol. , vol.33 , pp. 218-226
    • Liegl, B.1    Hornick, J.L.2    Antonescu, C.R.3    Corless, C.L.4    Fletcher, C.D.5
  • 57
    • 53449086305 scopus 로고    scopus 로고
    • Familial gastrointestinal stromal tumors caused by the novel KIT exon 17 germline mutation N822Y
    • Thalheimer A, Schlemmer M, Bueter M et al. Familial gastrointestinal stromal tumors caused by the novel KIT exon 17 germline mutation N822Y. Am. J. Surg. Pathol. 2008; 32; 1560-1565.
    • (2008) Am. J. Surg. Pathol. , vol.32 , pp. 1560-1565
    • Thalheimer, A.1    Schlemmer, M.2    Bueter, M.3
  • 58
    • 37349043267 scopus 로고    scopus 로고
    • Clinical, histopathologic, molecular and therapeutic findings in a large kindred with gastrointestinal stromal tumor
    • Kleinbaum EP, Lazar AJ, Tamborini E et al. Clinical, histopathologic, molecular and therapeutic findings in a large kindred with gastrointestinal stromal tumor. Int. J. Cancer 2008; 122; 711-718.
    • (2008) Int. J. Cancer , vol.122 , pp. 711-718
    • Kleinbaum, E.P.1    Lazar, A.J.2    Tamborini, E.3
  • 59
    • 66849135214 scopus 로고    scopus 로고
    • The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney-Stratakis syndrome): molecular genetics and clinical implications
    • Stratakis CA, Carney JA. The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney-Stratakis syndrome): molecular genetics and clinical implications. J. Intern. Med. 2009; 266; 43-52.
    • (2009) J. Intern. Med. , vol.266 , pp. 43-52
    • Stratakis, C.A.1    Carney, J.A.2
  • 60
    • 33644752349 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors in patients with neurofibromatosis 1: a clinicopathologic and molecular genetic study of 45 cases
    • Miettinen M, Fetsch JF, Sobin LH, Lasota J. Gastrointestinal stromal tumors in patients with neurofibromatosis 1: a clinicopathologic and molecular genetic study of 45 cases. Am. J. Surg. Pathol. 2006; 30; 90-96.
    • (2006) Am. J. Surg. Pathol. , vol.30 , pp. 90-96
    • Miettinen, M.1    Fetsch, J.F.2    Sobin, L.H.3    Lasota, J.4
  • 61
    • 19544389327 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors of neurofibromatosis type I (von Recklinghausen's disease)
    • Takazawa Y, Sakurai S, Sakuma Y et al. Gastrointestinal stromal tumors of neurofibromatosis type I (von Recklinghausen's disease). Am. J. Surg. Pathol. 2005; 29; 755-763.
    • (2005) Am. J. Surg. Pathol. , vol.29 , pp. 755-763
    • Takazawa, Y.1    Sakurai, S.2    Sakuma, Y.3
  • 62
    • 37349074531 scopus 로고    scopus 로고
    • Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD
    • Pasini B, McWhinney SR, Bei T et al. Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD. Eur. J. Hum. Genet. 2008; 16; 79-88.
    • (2008) Eur. J. Hum. Genet. , vol.16 , pp. 79-88
    • Pasini, B.1    McWhinney, S.R.2    Bei, T.3
  • 63
    • 34548051808 scopus 로고    scopus 로고
    • Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: a report of three new cases with mutational analysis and comparative genomic hybridization
    • Agaimy A, Pelz AF, Corless CL et al. Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: a report of three new cases with mutational analysis and comparative genomic hybridization. Oncol. Rep. 2007; 18; 9-15.
    • (2007) Oncol. Rep. , vol.18 , pp. 9-15
    • Agaimy, A.1    Pelz, A.F.2    Corless, C.L.3
  • 64
    • 0036499042 scopus 로고    scopus 로고
    • Familial paraganglioma and gastric stromal sarcoma: a new syndrome distinct from the Carney triad
    • Carney JA, Stratakis CA. Familial paraganglioma and gastric stromal sarcoma: a new syndrome distinct from the Carney triad. Am. J. Med. Genet. 2002; 108; 132-139.
    • (2002) Am. J. Med. Genet. , vol.108 , pp. 132-139
    • Carney, J.A.1    Stratakis, C.A.2
  • 65
    • 25444494428 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors of the stomach in children and young adults: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases with long-term follow-up and review of the literature
    • Miettinen M, Lasota J, Sobin LH. Gastrointestinal stromal tumors of the stomach in children and young adults: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases with long-term follow-up and review of the literature. Am. J. Surg. Pathol. 2005; 29; 1373-1381.
    • (2005) Am. J. Surg. Pathol. , vol.29 , pp. 1373-1381
    • Miettinen, M.1    Lasota, J.2    Sobin, L.H.3
  • 66
    • 20944442418 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literature
    • Prakash S, Sarran L, Socci N et al. Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literature. J. Pediatr. Hematol. Oncol. 2005; 27; 179-187.
    • (2005) J. Pediatr. Hematol. Oncol. , vol.27 , pp. 179-187
    • Prakash, S.1    Sarran, L.2    Socci, N.3
  • 68
    • 0032862462 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors/smooth muscle tumors (GISTs) primary in the omentum and mesentery: clinicopathologic and immunohistochemical study of 26 cases
    • Miettinen M, Monihan JM, Sarlomo-Rikala M et al. Gastrointestinal stromal tumors/smooth muscle tumors (GISTs) primary in the omentum and mesentery: clinicopathologic and immunohistochemical study of 26 cases. Am. J. Surg. Pathol. 1999; 23; 1109-1118.
    • (1999) Am. J. Surg. Pathol. , vol.23 , pp. 1109-1118
    • Miettinen, M.1    Monihan, J.M.2    Sarlomo-Rikala, M.3
  • 69
    • 33748601210 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumor of the prostate: a case report and literature review
    • Lee CH, Lin YH, Lin HY, Lee CM, Chu JS. Gastrointestinal stromal tumor of the prostate: a case report and literature review. Hum. Pathol. 2006; 37; 1361-1365.
    • (2006) Hum. Pathol. , vol.37 , pp. 1361-1365
    • Lee, C.H.1    Lin, Y.H.2    Lin, H.Y.3    Lee, C.M.4    Chu, J.S.5
  • 70
    • 33947274698 scopus 로고    scopus 로고
    • Extragastrointestinal stromal tumor presenting as a scrotal mass: an unusual case
    • Kang SH, Kim MJ, Park MG et al. Extragastrointestinal stromal tumor presenting as a scrotal mass: an unusual case. Asian J. Androl. 2007; 9; 275-279.
    • (2007) Asian J. Androl. , vol.9 , pp. 275-279
    • Kang, S.H.1    Kim, M.J.2    Park, M.G.3
  • 74
    • 67349288465 scopus 로고    scopus 로고
    • Extragastrointestinal stromal tumor arising in the rectovaginal septum: report of an unusual case with literature review
    • Zhang W, Peng Z, Xu L. Extragastrointestinal stromal tumor arising in the rectovaginal septum: report of an unusual case with literature review. Gynecol. Oncol. 2009; 113; 399-401.
    • (2009) Gynecol. Oncol. , vol.113 , pp. 399-401
    • Zhang, W.1    Peng, Z.2    Xu, L.3
  • 75
    • 33646437500 scopus 로고    scopus 로고
    • Reclassification of a tubal leiomyosarcoma as an eGIST by molecular evaluation of c-KIT
    • Foster R, Solano S, Mahoney J, Fuller A, Oliva E, Seiden MV. Reclassification of a tubal leiomyosarcoma as an eGIST by molecular evaluation of c-KIT. Gynecol. Oncol. 2006; 101; 363-366.
    • (2006) Gynecol. Oncol. , vol.101 , pp. 363-366
    • Foster, R.1    Solano, S.2    Mahoney, J.3    Fuller, A.4    Oliva, E.5    Seiden, M.V.6
  • 77
    • 21244460383 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors metastatic to the ovary: a report of five cases
    • Irving JA, Lerwill MF, Young RH. Gastrointestinal stromal tumors metastatic to the ovary: a report of five cases. Am. J. Surg. Pathol. 2005; 29; 920-926.
    • (2005) Am. J. Surg. Pathol. , vol.29 , pp. 920-926
    • Irving, J.A.1    Lerwill, M.F.2    Young, R.H.3
  • 78
    • 80054913507 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumours can express CD10 and epithelial membrane antigen but not oestrogen receptor or HMB45
    • press
    • Wong NA, Melegh Z. Gastrointestinal stromal tumours can express CD10 and epithelial membrane antigen but not oestrogen receptor or HMB45. Histopathology, in press.
    • Histopathology
    • Wong, N.A.1    Melegh, Z.2
  • 79
    • 43149124418 scopus 로고    scopus 로고
    • Estrogen and progesterone receptors expression in gastrointestinal stromal tumors and intramural gastrointestinal leiomyomas
    • Brodsky SV, Gimenez C, Ghosh C, Melamed M, Ramaswamy G. Estrogen and progesterone receptors expression in gastrointestinal stromal tumors and intramural gastrointestinal leiomyomas. Int. J. Gastrointest. Cancer 2006; 37; 129-132.
    • (2006) Int. J. Gastrointest. Cancer , vol.37 , pp. 129-132
    • Brodsky, S.V.1    Gimenez, C.2    Ghosh, C.3    Melamed, M.4    Ramaswamy, G.5
  • 80
    • 0033793213 scopus 로고    scopus 로고
    • Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT)
    • Miettinen M, Sobin LH, Sarlomo-Rikala M. Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT). Mod. Pathol. 2000; 13; 1134-1142.
    • (2000) Mod. Pathol. , vol.13 , pp. 1134-1142
    • Miettinen, M.1    Sobin, L.H.2    Sarlomo-Rikala, M.3
  • 81
    • 0035038941 scopus 로고    scopus 로고
    • Utility of CD10 in distinguishing between endometrial stromal sarcoma and uterine smooth muscle tumors: an immunohistochemical comparison of 34 cases
    • Chu PG, Arber DA, Weiss LM, Chang KL. Utility of CD10 in distinguishing between endometrial stromal sarcoma and uterine smooth muscle tumors: an immunohistochemical comparison of 34 cases. Mod. Pathol. 2001; 14; 465-471.
    • (2001) Mod. Pathol. , vol.14 , pp. 465-471
    • Chu, P.G.1    Arber, D.A.2    Weiss, L.M.3    Chang, K.L.4
  • 82
    • 0033015406 scopus 로고    scopus 로고
    • Progesterone receptor activity in leiomyomatosis peritonealis disseminata
    • Butnor KJ, Burchette JL, Robboy SJ. Progesterone receptor activity in leiomyomatosis peritonealis disseminata. Int. J. Gynecol. Pathol. 1999; 18; 259-264.
    • (1999) Int. J. Gynecol. Pathol. , vol.18 , pp. 259-264
    • Butnor, K.J.1    Burchette, J.L.2    Robboy, S.J.3
  • 83
    • 0034761583 scopus 로고    scopus 로고
    • Retroperitoneal leiomyomas: a clinicopathologic and immunohistochemical study of 56 cases with a comparison to retroperitoneal leiomyosarcomas
    • Paal E, Miettinen M. Retroperitoneal leiomyomas: a clinicopathologic and immunohistochemical study of 56 cases with a comparison to retroperitoneal leiomyosarcomas. Am. J. Surg. Pathol. 2001; 25; 1355-1363.
    • (2001) Am. J. Surg. Pathol. , vol.25 , pp. 1355-1363
    • Paal, E.1    Miettinen, M.2
  • 84
    • 77953079312 scopus 로고    scopus 로고
    • Primary extragastrointestinal stromal tumor of the pleura: report of a unique case with genetic confirmation
    • Long KB, Butrynski JE, Blank SD et al. Primary extragastrointestinal stromal tumor of the pleura: report of a unique case with genetic confirmation. Am. J. Surg. Pathol. 2010; 34; 907-912.
    • (2010) Am. J. Surg. Pathol. , vol.34 , pp. 907-912
    • Long, K.B.1    Butrynski, J.E.2    Blank, S.D.3
  • 85
    • 67650480850 scopus 로고    scopus 로고
    • V600E BRAF mutations are alternative early molecular events in a subset of KIT/PDGFRA wild-type gastrointestinal stromal tumours
    • Agaimy A, Terracciano LM, Dirnhofer S et al. V600E BRAF mutations are alternative early molecular events in a subset of KIT/PDGFRA wild-type gastrointestinal stromal tumours. J. Clin. Pathol. 2009; 62; 613-616.
    • (2009) J. Clin. Pathol. , vol.62 , pp. 613-616
    • Agaimy, A.1    Terracciano, L.M.2    Dirnhofer, S.3
  • 86
    • 73949094832 scopus 로고    scopus 로고
    • BRAF mutation status in gastrointestinal stromal tumors
    • Hostein I, Faur N, Primois C et al. BRAF mutation status in gastrointestinal stromal tumors. Am. J. Clin. Pathol. 2010; 133; 141-148.
    • (2010) Am. J. Clin. Pathol. , vol.133 , pp. 141-148
    • Hostein, I.1    Faur, N.2    Primois, C.3
  • 87
    • 77957941316 scopus 로고    scopus 로고
    • BRAF inhibitor unveils its potential against advanced melanoma
    • Vultur A, Villanueva J, Herlyn M. BRAF inhibitor unveils its potential against advanced melanoma. Cancer Cell 2010; 18; 301-302.
    • (2010) Cancer Cell , vol.18 , pp. 301-302
    • Vultur, A.1    Villanueva, J.2    Herlyn, M.3
  • 88
    • 46149104384 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors
    • Tarn C, Rink L, Merkel E et al. Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors. Proc. Natl. Acad. Sci. U S A 2008; 105; 8387-8392.
    • (2008) Proc. Natl. Acad. Sci. U S A , vol.105 , pp. 8387-8392
    • Tarn, C.1    Rink, L.2    Merkel, E.3
  • 89
    • 72449212435 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 receptor expression in wild-type GISTs: a potential novel therapeutic target
    • Pantaleo MA, Astolfi A, Di BM et al. Insulin-like growth factor 1 receptor expression in wild-type GISTs: a potential novel therapeutic target. Int. J. Cancer 2009; 125; 2991-2994.
    • (2009) Int. J. Cancer , vol.125 , pp. 2991-2994
    • Pantaleo, M.A.1    Astolfi, A.2    Di, B.M.3
  • 90
    • 78049495856 scopus 로고    scopus 로고
    • Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplification
    • Janeway KA, Zhu MJ, Barretina J, Perez-Atayde A, Demetri GD, Fletcher JA. Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplification. Int. J. Cancer 2010; 127; 2718-2722.
    • (2010) Int. J. Cancer , vol.127 , pp. 2718-2722
    • Janeway, K.A.1    Zhu, M.J.2    Barretina, J.3    Perez-Atayde, A.4    Demetri, G.D.5    Fletcher, J.A.6
  • 91
    • 46149111291 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients
    • Braconi C, Bracci R, Bearzi I et al. Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients. Ann. Oncol. 2008; 19; 1293-1298.
    • (2008) Ann. Oncol. , vol.19 , pp. 1293-1298
    • Braconi, C.1    Bracci, R.2    Bearzi, I.3
  • 92
    • 67651198212 scopus 로고    scopus 로고
    • An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis
    • van Nederveen FH, Gaal J, Favier J et al. An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis. Lancet Oncol. 2009; 10; 764-771.
    • (2009) Lancet Oncol. , vol.10 , pp. 764-771
    • van Nederveen, F.H.1    Gaal, J.2    Favier, J.3
  • 93
    • 77951809464 scopus 로고    scopus 로고
    • Immunohistochemistry for SDHB divides gastrointestinal stromal tumors (GISTs) into 2 distinct types
    • Gill AJ, Chou A, Vilain R et al. Immunohistochemistry for SDHB divides gastrointestinal stromal tumors (GISTs) into 2 distinct types. Am. J. Surg. Pathol. 2010; 34; 636-644.
    • (2010) Am. J. Surg. Pathol. , vol.34 , pp. 636-644
    • Gill, A.J.1    Chou, A.2    Vilain, R.3
  • 94
    • 78650866382 scopus 로고    scopus 로고
    • SDHB immunohistochemistry: a useful tool in the diagnosis of Carney-Stratakis and Carney triad gastrointestinal stromal tumors
    • Gaal J, Stratakis CA, Carney JA et al. SDHB immunohistochemistry: a useful tool in the diagnosis of Carney-Stratakis and Carney triad gastrointestinal stromal tumors. Mod. Pathol. 2011; 24; 147-151.
    • (2011) Mod. Pathol. , vol.24 , pp. 147-151
    • Gaal, J.1    Stratakis, C.A.2    Carney, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.