Reclassification of a tubal leiomyosarcoma as an eGIST by molecular evaluation of c-KIT

Gynecologic Oncology

Volumn 101, Issue 2, 2006, Pages 363-366

  Foster, Rosemary ^a   Solano, Steven ^a   Mahoney, Jennifer ^a   Fuller, Arlan ^a   Oliva, Esther ^a   Seiden, Michael V ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

c KIT mutation; eGIST; Imatinib; Sarcoma

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; DOXORUBICIN; IMATINIB; PLATINUM; PROTEIN TYROSINE KINASE; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR;

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER CLASSIFICATION; CANCER RADIOTHERAPY; CASE REPORT; DIFFERENTIAL DIAGNOSIS; DRUG TARGETING; EXTRAGASTROINTESTINAL STROMAL TUMOR; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; INTESTINE TUMOR; LEIOMYOSARCOMA; METASTASIS; MUTATIONAL ANALYSIS; OVARIECTOMY; PERITONEUM TUMOR; PRIORITY JOURNAL; RADIATION DOSE; RECURRENT CANCER; SMALL INTESTINE; SPINDLE CELL CARCINOMA; TUMOR; UTERINE TUBE TUMOR; VAGINAL HYSTERECTOMY;

BASE SEQUENCE; DIAGNOSIS, DIFFERENTIAL; FALLOPIAN TUBE NEOPLASMS; FEMALE; GASTROINTESTINAL STROMAL TUMORS; HUMANS; LEIOMYOSARCOMA; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROTO-ONCOGENE PROTEINS C-KIT;

EID: 33646437500     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1308/003588406X106540     Document Type: Article

References (23)

1. De Giorgi U., and Verweij J. Imatinib and gastrointestinal stromal tumors: where do we go from here?. Mol. Cancer Ther. 4 3 (2005) 495-501
2. Heinrich M.C., Rubin B.P., Longley B.J., and Fletcher J.A. Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations. Hum. Pathol. 33 5 (2002) 484-495
3. Hirota S., Isozaki K., Moriyama Y., Hashimoto K., Nishida T., Ishiguro S., et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 279 5350 (1998) 577-580
4. Hirota S., Nishida T., Isozaki K., Taniguchi M., Nakamura J., Okazaki T., et al. Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours. J. Pathol. 193 4 (2001) 505-510
5. Corless C.L., Fletcher J.A., and Heinrich M.C. Biology of gastrointestinal stromal tumors. J. Clin. Oncol. 22 18 (2004) 3813-3825
6. Reith J.D., Goldblum J.R., Lyles R.H., and Weiss S.W. Extragastrointestinal (soft tissue) stromal tumors: an analysis of 48 cases with emphasis on histologic predictors of outcome. Mod. Pathol. 13 5 (2000) 577-585
7. Froehner M., Ockert D., Aust D.E., Wirth M.P., and Saeger H.D. Gastrointestinal stromal tumor presenting as a scrotal mass. Int. J. Urol. 11 6 (2004) 445-447
8. Krokowski M., Jocham D., Choi H., Feller A.C., and Horny H.P. Malignant extragastrointestinal stromal tumor of bladder. J. Urol. 169 5 (2003) 1790-1791
9. Carlomagno G., and Beneduce P. A gastrointestinal stromal tumor (GIST) masquerading as an ovarian mass. World J. Surg. Oncol. 2 1 (2004) 15
10. Zighelboim I., Henao G., Kunda A., Gutierrez C., and Edwards C. Gastrointestinal stromal tumor presenting as a pelvic mass. Gynecol. Oncol. 91 3 (2003) 630-635
11. Nakagawa M., Akasaka Y., Kanai T., Yamashita T., Kuroda M., Takayama H., et al. Extragastrointestinal stromal tumor of the greater omentum: case report and review of the literature. Hepatogastroenterology 50 51 (2003) 691-695
12. Siddiq M.A., East D., Hock Y.L., and Warfield A.T. Gastrointestinal stromal tumour of the pharynx. J. Laryngol. Otol. 118 4 (2004) 315-316
13. Goyal A., Mansel R.E., and Goyal S. Gastrointestinal stromal tumour in an inguinal hernial sac: an unusual presentation. Postgrad. Med. J. 79 938 (2003) 707-708
14. Neto M.R., Machuca T.N., Pinho R.V., Yuasa L.D., and Bleggi-Torres L.F. Gastrointestinal stromal tumor: report of two unusual cases. Virchows Arch. 444 6 (2004) 594-596
15. Nasu K., Ueda T., Kai S., Anai H., Kimura Y., Yokoyama S., et al. Gastrointestinal stromal tumor arising in the rectovaginal septum. Int. J. Gynecol. Cancer 14 2 (2004) 373-377
16. Irving J.A., Lerwill M.F., and Young R.H. Gastrointestinal stromal tumors metastatic to the ovary: a report of five cases. Am. J. Surg. Pathol. 29 7 (2005) 920-926
17. Raspollini M.R., Villanucci A., Amunni G., Paglierani M., Taddei A., and Taddei G.L. C-kit expression in uterine leiomyosarcomas: an immunocytochemical study of 29 cases of malignant smooth muscle tumors of the uterus. J. Chemother. 15 1 (2003) 81-84
18. Winter III W.E., Seidman J.D., Krivak T.C., Chauhan S., Carlson J.W., Rose G.S., et al. Clinicopathological analysis of c-kit expression in carcinosarcomas and leiomyosarcomas of the uterine corpus. Gynecol. Oncol. 91 1 (2003) 3-8
19. Tarn C., Merkel E., Canutescu A.A., Shen W., Skorobogatko Y., Heslin M.J., et al. Analysis of KIT mutations in sporadic and familial gastrointestinal stromal tumors: therapeutic implications through protein modeling. Clin. Cancer Res. 11 10 (2005) 3668-3677
20. Chen L.L., Trent J.C., Wu E.F., Fuller G.N., Ramdas L., Zhang W., et al. A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors. Cancer Res. 64 17 (2004) 5913-5919
21. Duensing A., Medeiros F., McConarty B., Joseph N.E., Panigrahy D., Singer S., et al. Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs). Oncogene 23 22 (2004) 3999-4006
22. Carter T.A., Wodicka L.M., Shah N.P., Velasco A.M., Fabian M.A., Treiber D.K., et al. Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases. Proc. Natl. Acad. Sci. U. S. A. 102 31 (2005) 11011-11016
23. Fiedler W., Serve H., Dohner H., Schwittay M., Ottmann O.G., O'Farrell A.M., et al. A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease. Blood 105 3 (2005) 986-993