The nature of the dietary protein impacts the tissue-to-diet 15n discrimination factors in laboratory rats

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Poupin, Nathalie ^a,b   Bos, Cécile ^a,b   Mariotti, François ^a,b   Huneau, Jean François ^a,b   Tomé, Daniel ^a,b   Fouillet, Hélène ^a,b  

^a INRA Institut National de la Recherche Agronomique   (France)

^b CENTRE MAURICE HALBWACHS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; MILK PROTEIN; NITROGEN 15; SOYBEAN PROTEIN; STABLE ISOTOPE; UREA; NITROGEN;

AMINO ACID COMPOSITION; AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY WEIGHT; CONTROLLED STUDY; ISOTOPE ANALYSIS; MALE; METABOLIC REGULATION; NITROGEN CONCENTRATION; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; PROTEIN DETERMINATION; PROTEIN INTAKE; PROTEIN MODIFICATION; PROTEIN SYNTHESIS; RAT; TISSUE DISTRIBUTION; TISSUE METABOLISM; UREA BLOOD LEVEL; ANIMAL; ANTIBODY SPECIFICITY; BLOOD; DIET; DRUG EFFECT; LABORATORY; METABOLISM; ORGAN SIZE; WISTAR RAT;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

ANIMALS; BODY COMPOSITION; BODY WEIGHT; DIET; DIETARY PROTEINS; LABORATORIES; MALE; NITROGEN; NITROGEN ISOTOPES; ORGAN SIZE; ORGAN SPECIFICITY; RATS; RATS, WISTAR;

EID: 81555212325     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028046     Document Type: Article

References (55)

1. Caut S, Angulo E, Courchamp F, (2008) Discrimination factors (Delta N-15 and Delta C-13) in an omnivorous consumer: effect of diet isotopic ratio. Funct Ecol 22: 255-263.
2. Dalerum F, Angerbjorn A, (2005) Resolving temporal variation in vertebrate diets using naturally occurring stable isotopes. Oecologia 144: 647-658.
3. Hobson KA, (1999) Tracing origins and migration of wildlife using stable isotopes: a review. Oecologia 120: 314-326.
4. DeNiro MJ, Epstein S, (1981) Influence of diet on the distribution of nitrogen isotopes in animals. Geochim Cosmochim Acta 45: 341-351.
5. Caut S, Angulo E, Courchamp F, (2009) Variation in discrimination factors (Delta N-15 and Delta C-13): the effect of diet isotopic values and applications for diet reconstruction. J Appl Ecol 46: 443-453.
6. Vanderklift MA, Ponsard S, (2003) Sources of variation in consumer-diet delta N-15 enrichment: a meta-analysis. Oecologia 136: 169-182.
7. Hayes JM, (2001) Fractionation of carbon and hydrogen isotopes in biosynthetic processes. Stable Isotope Geochemistry Washington Mineralogical Soc America pp. 225-277.
8. Gaebler OH, Vitti TG, Vukmirovich R, (1966) Isotope effects in metabolism of 14N and 15N from unlabeled dietary proteins. Can J Biochem 44: 1249-1257.
9. Macko SA, Estep MLF, Engel MH, Hare PE, (1986) Kinetic fractionation of stable nitrogen isotopes during amino-acid transamination. Geochim Cosmochim Acta 50: 2143-2146.
10. Gannes LZ, del Rio CM, Koch P, (1998) Natural abundance variations in stable isotopes and their potential uses in animal physiological ecology. Comp Biochem Physiol A-Mol Integr Physiol 119: 725-737.
11. Steele KW, Daniel RM, (1978) Fractionation of nitrogen isotopes by animals- a further complication to use of variations in natural abundance of n-15 for tracer studies. J Agric Sci 90: 7-9.
12. Petzke KJ, Boeing H, Klaus S, Metges CC, (2005) Carbon and nitrogen stable isotopic composition of hair protein and amino acids can be used as biomarkers for animal-derived dietary protein intake in humans. J Nutr 135: 1515-1520.
13. Fuller BT, Fuller JL, Sage NE, Harris DA, O'Connell TC, et al. (2004) Nitrogen balance and delta N-15: why you're not what you eat during pregnancy. Rapid Commun Mass Spectrom 18: 2889-2896.
14. Fuller BT, Fuller JL, Sage NE, Harris DA, O'Connell TC, et al. (2005) Nitrogen balance and delta N-15: why you're not what you eat during nutritional stress. Rapid Commun Mass Spectrom 19: 2497-2506.
15. Mekota AM, Grupe G, Ufer S, Cuntz U, (2006) Serial analysis of stable nitrogen and carbon isotopes in hair: monitoring starvation and recovery phases of patients suffering from anorexia nervosa. Rapid Commun Mass Spectrom 20: 1604-1610.
16. Petzke KJ, Feist T, Fleig WE, Metges CC, (2006) Nitrogen isotopic composition in hair protein is different in liver cirrhotic patients. Rapid Commun Mass Spectrom 20: 2973-2978.
17. Martinez del Rio C, Wolf BO, (2005) Mass-balance models for animal isotopic ecology. In: Starck JM, Wang T, editors. Physiological and ecological adaptations to feeding in vertebrates Science Publishers, Inc pp. 141-174.
18. Barboza PS, Parker KL, (2006) Body protein stores and isotopic indicators of N balance in female reindeer (Rangifer tarandus) during winter. Physiol Biochem Zool 79: 628-644.
19. Ponsard S, Averbuch P, (1999) Should growing and adult animals fed on the same diet show different delta N-15 values? Rapid Commun Mass Spectrom 13: 1305-1310.
20. Robbins CT, Felicetti LA, Sponheimer M, (2005) The effect of dietary protein quality on nitrogen isotope discrimination in mammals and birds. Oecologia 144: 534-540.
21. Vander Zanden MJ, Rasmussen JB, (2001) Variation in delta N-15 and delta C-13 trophic fractionation: Implications for aquatic food web studies. Limnol Oceanogr 46: 2061-2066.
22. Martinez del Rio C, Wolf N, Carleton SA, Gannes LZ, (2009) Isotopic ecology ten years after a call for more laboratory experiments. Biol Rev 84: 91-111.
23. Gaye-Siessegger J, Focken U, Abel H, Becker K, (2004) Individual protein balance strongly influences delta N-15 and delta C-13 values in Nile tilapia, Oreochromis niloticus. Naturwissenschaften 91: 90-93.
24. Waters-Rist AL, Katzenberg MA, (2010) The Effect of Growth on Stable Nitrogen Isotope Ratios in Subadult Bone Collagen. Int J Osteoarchaeol 20: 172-191.
25. Deutz NEP, Bruins MJ, Soeters PB, (1998) Infusion of soy and casein protein meals affects interorgan amino acid metabolism and urea kinetics differently in pigs. J Nutr 128: 2435-2445.
26. Fouillet H, Juillet B, Gaudichon C, Mariotti F, Tome D, et al. (2009) Absorption kinetics are a key factor regulating postprandial protein metabolism in response to qualitative and quantitative variations in protein intake. Am J Physiol Regul Integr Comp Physiol 297: R1691-R1705.
27. Morens C, Bos C, Pueyo ME, Benamouzig R, Gausseres N, et al. (2003) Increasing habitual protein intake accentuates differences in postprandial dietary nitrogen utilization between protein sources in humans. J Nutr 133: 2733-2740.
28. Fouillet H, Mariotti F, Gaudichon C, Bos C, Tome D, (2002) Peripheral and splanchnic metabolism of dietary nitrogen are differently affected by the protein source in humans as assessed by compartmental modeling. J Nutr 132: 125-133.
29. O'Brien DM, Kristal AR, Jeannet MA, Wilkinson MJ, Bersamin A, et al. (2009) Red blood cell delta N-15: a novel biomarker of dietary eicosapentaenoic acid and docosahexaenoic acid intake. Am J Clin Nutr 89: 913-919.
30. Ambrose SH, (2000) Controlled diet and climate experiments on nitrogen isotope ratios of rats. In: Ambrose SH, Katzenberg MA, editors. Biogeochemical approaches to paledietary analysis New York Kluwer Academic Publishers pp. 243-259.
31. Arneson LS, MacAvoy SE, (2005) Carbon, nitrogen, and sulfur diet-tissue discrimination in mouse tissues. Can J Zool 83: 989-995.
32. DeMots RL, Novak JM, Gaines KF, Gregor AJ, Romanek CS, et al. (2010) Tissue-diet discrimination factors and turnover of stable carbon and nitrogen isotopes in white-footed mice (Peromyscus leucopus). Can J Zool 88: 961-967.
33. Kurle CM, (2009) Interpreting temporal variation in omnivore foraging ecology via stable isotope modelling. Funct Ecol 23: 733-744.
34. Robbins CT, Felicetti LA, Florin ST, (2009) The impact of protein quality on stable nitrogen isotope ratio discrimination and assimilated diet estimation. Oecologia 162: 571-579.
35. Yoneyama T, Ohta Y, Ohtani T, (1983) Variations of natural carbon-13 and nitrogen-15 abundances in rat tissues and their correlation. Radioisotopes 32: 330-332.
36. MacAvoy SE, Arneson LS, Bassett E, (2006) Correlation of metabolism with tissue carbon and nitrogen turnover rate in small mammals. Oecologia 150: 190-201.
37. Schoeller DA, (1999) Isotope fractionation: Why aren't we what we eat? J Archaeol Sci 26: 667-673.
38. Sick H, Roos N, Saggau E, Haas K, Meyn V, et al. (1997) Amino acid utilization and isotope discrimination of amino nitrogen in nitrogen metabolism of rat liver in vivo. Z Ernahrung 36: 340-346.
39. Sponheimer M, Robinson TF, Roeder BL, Passey BH, Ayliffe LK, et al. (2003) An experimental study of nitrogen flux in llamas: is N-14 preferentially excreted? J Archaeol Sci 30: 1649-1655.
40. Roth JD, Hobson KA, (2000) Stable carbon and nitrogen isotopic fractionation between diet and tissue of captive red fox: implications for dietary reconstruction. Can J Zool 78: 848-852.
41. Seila AC, Okuda K, Nunez S, Seila AF, Strobel SA, (2005) Kinetic isotope effect analysis of the ribosomal peptidyl transferase reaction. Biochemistry 44: 4018-4027.
42. Silfer JA, Engel MH, Macko SA, (1992) Kinetic fractionation of stable carbon and nitrogen isotopes during peptide-bond hydrolysis- experimental-evidence and geochemical implications. Chem Geol 101: 211-221.
43. Lohrke B, Saggau E, Schadereit R, Beyer M, Bellmann O, et al. (2001) Activation of skeletal muscle protein breakdown following consumption of soyabean protein in pigs. Br J Nutr 85: 447-457.
44. Fouillet H, Bos C, Gaudichon C, Tome D, (2002) Approaches to quantifying protein metabolism in response to nutrient ingestion. J Nutr 132: 3208S-3218S.
45. Smith K, Rennie MJ, (1996) The measurement of tissue protein turnover. Baillieres Clin Endocrinol Metab 10: 469-495.
46. MacAvoy SE, Macko SA, Arneson LS, (2005) Growth versus metabolic tissue replacment in mouse tissues. Canadian Journal of Zoology-Revue Canadienne De Zoologie 83: 631-641.
47. Arneson LS, MacAvoy S, Basset E, (2006) Metabolic protein replacement drives tissue turnover in adult mice. Can J Zool 84: 992-1002.
48. Balter V, Simon L, Fouillet H, Lecuyer C, (2006) Box-modeling of N-15/N-14 in mammals. Oecologia 147: 212-222.
49. Blakey GE, Nestorov IA, Arundel PA, Aarons LJ, Rowland M, (1997) Quantitative structure-pharmacokinetics relationships: I. Development of a whole-body physiologically based model to characterize changes in pharmacokinetics across a homologous series of barbiturates in the rat. J Pharmacokinet Biopharm 25: 277-312.
50. Morens C, Gaudichon C, Metges CC, Fromentin G, Baglieri A, et al. (2000) A high-protein meal exceeds anabolic and catabolic capacities in rats adapted to a normal protein diet. J Nutr 130: 2312-2321.
51. Lacroix M, Gaudichon C, Martin A, Morens C, Mathe V, et al. (2004) A long-term high-protein diet markedly reduces adipose tissue without major side effects in Wistar male rats. Am J Physiol Regul Integr Comp Physiol 287: R934-R942.
52. Waynforth HB, (1980) Experimental and surgical technique in the rat. Experimental and surgical technique in the rat London UK Academic Press pp. xv + 269.
53. Morens C, Gaudichon C, Fromentin GE, Marsset-Baglieri A, Bensaid A, et al. (2001) Daily delivery of dietary nitrogen to the periphery is stable in rats adapted to increased protein intake. Am J Physiol Endocrinol Metab 281: E826-E836.
54. Boutry C, Fouillet H, Mariotti F, Blachier F, Tome D, et al. (2011) Rapeseed and milk protein exhibit a similar overall nutritional value but marked difference in postprandial regional nitrogen utilization in rats. Nutr Metab (Lond) 8: 52.
55. Sharp PE, M.C. L, (1998) The laboratory rat The Laboratory Animal Pocket Reference Series: CRC Press LLC.