Process development for a key synthetic intermediate of LY2140023, a clinical candidate for the treatment of schizophrenia

Organic Process Research and Development

Volumn 15, Issue 6, 2011, Pages 1266-1274

  Waser, Mario ^a   Moher, Eric D ^b   Borders, Sandy S K ^b   Hansen, Marvin M ^b   Hoard, David W ^b   Laurila, Michael E ^b   Letourneau, Michael E ^b   Miller, Richard D ^b   Phillips, Michael L ^b   Sullivan, Kevin A ^b   Ward, Jeffrey A ^b   Xie, Chaoyu ^b   Bye, Cheryl A ^b   Leitner, Tanja ^a   Herzog Krimbacher, Brigitte ^a   Kordian, Marcus ^a   Müllner, Martin ^a  

^a DSM Fine Chemicals Austria Nfg GmbH & Co KG   (Netherlands)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL DEVELOPMENT; CYCLOPROPANATION; DOUBLE BONDS; HYDANTOINS; HYDROBORATION; L-GLUTAMIC ACIDS; MULTI-STEP; OXIDATION STATE; PROCESS DEVELOPMENT; PROTECTING GROUP; REGIOSELECTIVE FUNCTIONALIZATION; SYNTHETIC INTERMEDIATES;

AMINO ACIDS; RHODIUM; SYNTHESIS (CHEMICAL); THIOPHENE;

REACTION INTERMEDIATES;

EID: 81555200734     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op100325h     Document Type: Article

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