Estrogen increases nitric-oxide production in human bronchial epithelium

Journal of Pharmacology and Experimental Therapeutics

Volumn 339, Issue 3, 2011, Pages 815-824

  Townsend, Elizabeth A ^a   Meuchel, Lucas W ^a   Thompson, Michael A ^b   Pabelick, Christina M ^a,b   Prakash, Y S ^a,b  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,11 DIETHYL 5,6,11,12 TETRAHYDRO 2,8 CHRYSENEDIOL; ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; CALCIUM; CAVEOLIN 1; DIARYLPROPIONITRILE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT; HORMONE RECEPTOR STIMULATING AGENT; NITRIC OXIDE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BRONCHODILATATION; BRONCHOSPASM; BRONCHUS MUCOSA; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL;

AGED; BRONCHI; BRONCHODILATOR AGENTS; CALCIUM; ENDOTHELIUM, VASCULAR; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGENS; FEMALE; FLUORESCEINS; FLUORESCENT DYES; HUMANS; HYDRAZINES; MIDDLE AGED; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, ESTROGEN; RESPIRATORY MUCOSA; SEX FACTORS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 81555195493     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.184416     Document Type: Article

References (41)

1. Becklake MR and Kauffmann F (1999) Gender differences in airway behaviour over the human life span. Thorax 54:1119-1138.
2. Bellia V and Augugliaro G (2007) Asthma and menopause. Monaldi Arch Chest Dis 67:125-127. (Pubitemid 350065965)
3. Belvisi MG, Ward JK, Mitchell JA, and Barnes PJ (1995) Nitric oxide as a neurotransmitter in human airways. Arch Int Pharmacodyn Ther 329:97-110.
4. Boitano S, Dirksen ER, and Sanderson MJ (1992) Intercellular propagation of calcium waves mediated by inositol trisphosphate. Science 258:292-295.
5. Bove PF and van der Vliet A (2006) Nitric oxide and reactive nitrogen species in airway epithelial signaling and inflammation. Free Radic Biol Med 41:515-527. (Pubitemid 44080515)
6. Chhabra SK (2005) Premenstrual asthma. Indian J Chest Dis Allied Sci 47:109-116.
7. Di Maria GU, Spicuzza L, Mistretta A, and Mazzarella G (2000) Role of endogenous nitric oxide in asthma. Allergy 55(Suppl 61):31-35. (Pubitemid 30430376)
8. Dimitropoulou C, White RE, Ownby DR, and Catravas JD (2005) Estrogen reduces carbachol-induced constriction of asthmatic airways by stimulating large-conductance voltage and calcium-dependent potassium channels. Am J Respir Cell Mol Biol 32:239-247. (Pubitemid 40387651)
9. Farha S, Asosingh K, Laskowski D, Hammel J, Dweik RA, Wiedemann HP, and Erzurum SC (2009) Effects of the menstrual cycle on lung function variables in women with asthma. Am J Respir Crit Care Med 180:304-310.
10. Feletou M, Lonchampt M, Coge F, Galizzi JP, Bassoullet C, Merial C, Robineau P, Boutin JA, Huang PL, Vanhoutte PM, et al. (2001) Regulation of murine airway responsiveness by endothelial nitric oxide synthase. Am J Physiol Lung Cell Mol Physiol 281:L258-L267.
11. Folkerts G and Nijkamp FP (2006) Nitric oxide in asthma therapy. Curr Pharm Des 12:3221-3232. (Pubitemid 44364134)
12. García-Cardeña G, Martasek P, Masters BS, Skidd PM, Couet J, Li S, Lisanti MP, and Sessa WC (1997) Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the nos caveolin binding domain in vivo. J Biol Chem 272:25437-25440. (Pubitemid 27438846)
13. Gibbs CJ, Coutts II, Lock R, Finnegan OC, and White RJ (1984) Premenstrual exacerbation of asthma. Thorax 39:833-836. (Pubitemid 14022733)
14. Hanley SP (1981) Asthma variation with menstruation. Br J Dis Chest 75:306-308.
15. Heldring N, Pike A, Andersson S, Matthews J, Cheng G, Hartman J, Tujague M, Ström A, Treuter E, Warner M, et al. (2007) Estrogen receptors: how do they signal and what are their targets. Physiol Rev 87:905-931. (Pubitemid 47084672)
16. Hisamoto K and Bender JR (2005) Vascular cell signaling by membrane estrogen receptors. Steroids 70:382-387. (Pubitemid 40616036)
17. Hurt KJ, Musicki B, Palese MA, Crone JK, Becker RE, Moriarity JL, Snyder SH, and Burnett AL (2002) Akt-dependent phosphorylation of endothelial nitric-oxide synthase mediates penile erection. Proc Natl Acad Sci U S A 99:4061-4066. (Pubitemid 34252229)
18. Ivanova MM, Mazhawidza W, Dougherty SM, Minna JD, and Klinge CM (2009) Activity and intracellular location of estrogen receptors α and β in human bronchial epithelial cells. Mol Cell Endocrinol 305:12-21.
19. Jiang J, Malavia N, Suresh V, and George SC (2009) Nitric oxide gas phase release in human small airway epithelial cells. Respir Res 10:3.
20. Ju H, Zou R, Venema VJ, and Venema RC (1997) Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activity. J Biol Chem 272:18522-18525. (Pubitemid 27318186)
21. Kharitonov SA, Logan-Sinclair RB, Busset CM, and Shinebourne EA (1994) Peak expiratory nitric oxide differences in men and women: relation to the menstrual cycle. Br Heart J 72:243-245. (Pubitemid 24288735)
22. Kirsch EA, Yuhanna IS, Chen Z, German Z, Sherman TS, and Shaul PW (1999) Estrogen acutely stimulates endothelial nitric oxide synthase in H441 human airway epithelial cells. Am J Respir Cell Mol Biol 20:658-666. (Pubitemid 129495654)
23. Klinge CM, Wickramasinghe NS, Ivanova MM, and Dougherty SM (2008) Resveratrol stimulates nitric oxide production by increasing estrogen receptor α-Src-caveolin-1 interaction and phosphorylation in human umbilical vein endothelial cells. FASEB J 22:2185-2197. (Pubitemid 351948638)
24. Kone BC (2000) Protein-protein interactions controlling nitric oxide synthases. Acta Physiol Scand 168:27-31.
25. Krasteva G, Pfeil U, Drab M, Kummer W, and König P (2006) Caveolin-1 and -2 in airway epithelium: expression and in situ association as detected by FRET-CLSM. Respir Res 7:108.
26. Lammers JW, Barnes PJ, and Chung KF (1992) Nonadrenergic, noncholinergic airway inhibitory nerves. Eur Respir J 5:239-246.
27. Langer G, Bader B, Meoli L, Isensee J, Delbeck M, Noppinger PR, and Otto C (2010) A critical review of fundamental controversies in the field of GPR30 research. Steroids 75:603-610.
28. Levin ER (2002) Cellular functions of plasma membrane estrogen receptors. Steroids 67:471-475.
29. Mandhane PJ, Hanna SE, Inman MD, Duncan JM, Greene JM, Wang HY, and Sears MR (2009) Changes in exhaled nitric oxide related to estrogen and progesterone during the menstrual cycle. Chest 136:1301-1307.
30. Melgert BN, Ray A, Hylkema MN, Timens W, and Postma DS (2007) Are there reasons why adult asthma is more common in females? Curr Allergy Asthma Rep 7:143-150. (Pubitemid 46736336)
31. Meuchel LW, Thompson MA, Cassivi SD, Pabelick CM, and Prakash YS (2011) Neurotrophins induce nitric oxide generation in human pulmonary artery endothelial cells. Cardiovasc Res 91:668-676.
32. Murphy VE and Gibson PG (2008) Premenstrual asthma: prevalence, cycle-to-cycle variability and relationship to oral contraceptive use and menstrual symptoms. J Asthma 45:696-704.
33. Nijkamp FP and Folkerts G (1995) Nitric oxide and bronchial hyperresponsiveness. Arch Int Pharmacodyn Ther 329:81-96.
34. Ortiz PA and Garvin JL (2003) Trafficking and activation of eNOS in epithelial cells. Acta Physiol Scand 179:107-114. (Pubitemid 37249244)
35. Postma DS (2007) Gender differences in asthma development and progression. Gend Med 4(Suppl B):S133-S146.
36. Ricciardolo FL, Sterk PJ, Gaston B, and Folkerts G (2004) Nitric oxide in health and disease of the respiratory system. Physiol Rev 84:731-765. (Pubitemid 38823765)
37. Schatz M and Camargo CA Jr (2003) The relationship of sex to asthma prevalence, health care utilization, and medications in a large managed care organization. Ann Allergy Asthma Immunol 91:553-558. (Pubitemid 38017979)
38. Shaul PW (2002) Regulation of endothelial nitric oxide synthase: location, location, location. Annu Rev Physiol 64:749-774.
39. Simoncini T and Genazzani AR (2003) Non-genomic actions of sex steroid hormones. Eur J Endocrinol 148:281-292. (Pubitemid 36410713)
40. 2+ regulation in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 298:L521-L530.
41. Vrieze A, Postma DS, and Kerstjens HA (2003) Perimenstrual asthma: a syndrome without known cause or cure. J Allergy Clin Immunol 112:271-282. (Pubitemid 36981366)