Improvement of porcine interferon-α production by recombinant pichia pastoris via induction at low methanol concentration and low temperature

Applied Biochemistry and Biotechnology

Volumn 165, Issue 2, 2011, Pages 559-571

  Jin, Hu ^a   Liu, Guoqiang ^a   Dai, Keke ^a   Wang, Huihui ^a   Li, Zhen ^b   Shi, Zhongping ^a  

^a JIANGNAN UNIVERSITY   (China)

^b INSTITUTE OF EDIBLE FUNGI   (China)

Author keywords

Fed batch cultivation; Induction; Metabolic flux; Pichia pastoris; Porcine interferon

Indexed keywords

ALCOHOL OXIDASE; CARBON FLUXES; CULTURE CONDITIONS; EXTRACELLULAR PROTEASE; FED-BATCH CULTIVATION; FORMALDEHYDE DEHYDROGENASE; FORMATE DEHYDROGENASE; INDUCTION; INDUCTION TEMPERATURES; LOW TEMPERATURES; METABOLIC ACTIVITY; METABOLIC FLUX; METHANOL CONCENTRATION; METHANOL CONSUMPTION RATE; PICHIA PASTORIS; POTENTIAL MECHANISM; SPECIFIC ACTIVITY;

ANTIBIOTICS; CELL CULTURE; CONCENTRATION (PROCESS); GLYCOPROTEINS; METABOLISM; METHANOL; OPTIMIZATION; YEAST;

LOW TEMPERATURE PRODUCTION;

ALCOHOL OXIDASE; ALPHA INTERFERON; FORMALDEHYDE DEHYDROGENASE; FORMATE DEHYDROGENASE; METHANOL; PROTEINASE;

ANIMAL TISSUE; ARTICLE; BIOREACTOR; CELL CULTURE; NONHUMAN; PICHIA PASTORIS; SWINE; TEMPERATURE MEASUREMENT;

ALCOHOL OXIDOREDUCTASES; ALDEHYDE OXIDOREDUCTASES; ANIMALS; BIOREACTORS; CULTURE MEDIA; FERMENTATION; FORMATE DEHYDROGENASES; INDUSTRIAL MICROBIOLOGY; INTERFERON-ALPHA; METHANOL; PICHIA; RECOMBINANT PROTEINS; SWINE; TEMPERATURE; TRANSCRIPTIONAL ACTIVATION;

PICHIA PASTORIS; SUS;

EID: 81455135465     PISSN: 02732289     EISSN: 15590291     Source Type: Journal    
DOI: 10.1007/s12010-011-9275-2     Document Type: Article

References (22)

1. Macauley-Patrick, S., Fazenda, M., McNeil, B., & Harvey, L. (2005). Yeast, 22, 249-270.
2. Cereghino, L., & Cregg, J. M. (2000). FEMS Microbiology Reviews, 24, 45-66.
3. Huang, H., Xie, P., Yu, R. S., Liu, H. L., Zhang, D. F., Cao, X. R., et al. (2005). Hereditas, 27, 215-220.
4. Ge, L., Li, Z., Yu, R. S., Liu, H. L., Zhang, D. F., Zhou, Z. A., et al. (2005). Chinese Journal of Veterinary Science, 25, 289-292.
5. Higgins, D. R., & Cregg, J. M. (1998). Methods in molecular biology: Pichia protocols (pp. 1-15). Totowa: Humana.
6. Hong, F., Meinander, N. Q., & Jönsson, L. J. (2002). Biotechnology and Bioengineering, 79, 438-449.
7. Jahic, M., Wallberg, F., Bollok, M., Garcia, P., & Enfors, S. O. (2003). Microbial Cell Factories, 2, 6.
8. Dragosits, M., Stadlmann, J., Albiol, J., Baumann, K., Maurer, M., Gasser, B., et al. (2009). Journal of Proteome Research, 8, 1380-1392.
9. Stratton, J., Chiruvolu, V., & Meagher, M. (1998). Methods in Molecular Biology, 103, 107-120.
10. Khatri, N. K., & Hoffmann, F. (2006). Biotechnology and Bioengineering, 93, 871-879.
11. Gellissen, G. (2002). Hansenula polymorpha-biology and applications. Weinheim: Wiley-VCH.
12. Sakai, Y., Murdanoto, A. P., Konishi, T., Iwamatsu, A., & Kato, N. (1997). Journal of Bacteriology, 179, 4480-4485.
13. Lee, B., Yurimoto, H., Sakai, Y., & Kato, N. (2002). Microbiology, 148, 2697-2704.
14. Katakura, Y., Zhang, W., Zhuang, G., Omasa, T., Kishimoto, M., Goto, Y., et al. (1998). Journal of Fermentation and Bioengineering, 86, 482-487.
15. Tian, M. Y., Huitema, E., da Cunha, L., Torto-Alalibo, T., & Kamoun, S. (2004). Journal of Biological Chemistry, 279, 26370-26377.
16. Suye, S. I., Ogawa, A., Yokoyama, S., & Obayashi, A. (1990). Agricultural and Biological Chemistry, 54, 1297-1298.
17. Schütte, H., Flossdorf, J., Sahm, H., & Kula, M. R. (1976). European Journal of Biochemistry, 62, 151-160.
18. Yu, R. S., Dong, S. J., Zhu, Y. M., Jin, H., Gao, M. J., Duan, Z. Y., et al. (2010). Bioprocess and Biosystems Engineering, 33, 473-483.
19. Jin, H., Zheng, Z. Y., Gao, M. J., Duan, Z. Y., Shi, Z. P., Wang, Z. X., et al. (2007). Biochemical Engineering Journal, 37, 26-33.
20. Duan, S. B., Shi, Z. P., Feng, H. J., Duan, Z. Y., & Mao, Z. G. (2006). Biochemical Engineering Journal, 30, 88-96.
21. Sakai, Y., Nakagawa, T., Shimase, M., & Kato, N. (1998). Journal of Bacteriology, 180, 5885-5890.
22. Sibirny, A. A., Ubiyvovk, V. M., Gonchar, M. V., Titorenko, V. I., Voronovsky, A. Y., Kapultsevich, Y. G., et al. (1990). Archives of Microbiology, 154, 566-575.