Pathogenesis of collagen-induced arthritis: Modulation of disease by arthritogenic T-cell epitope location

Immunology

Volumn 113, Issue 3, 2004, Pages 384-391

  Tang, Bo ^a,b   Brand, David D ^a,b   Ma, Zhijun ^a   Stuart, John M ^a,b   Myers, Linda K ^a   Kang, Andrew H ^a,b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Arthritis; Autoantibodies; Collagen type II; Mutagenesis; T cell epitope

Indexed keywords

COLLAGEN; COLLAGEN TYPE 2; CYTOKINE; EPITOPE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPITOPE MAPPING; FLOW CYTOMETRY; IMMUNOPATHOGENESIS; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; T LYMPHOCYTE ACTIVATION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; AUTOANTIBODIES; CELL DIVISION; CELLS, CULTURED; COLLAGEN; CYANOGEN BROMIDE; CYTOKINES; DISEASE SUSCEPTIBILITY; EPITOPES, B-LYMPHOCYTE; EPITOPES, T-LYMPHOCYTE; LYMPHOCYTE ACTIVATION; MICE; MUTAGENESIS; RECOMBINANT FUSION PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 8144229301     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2004.01987.x     Document Type: Article

References (18)

1. Myers LK, Rosloniec EF, Cremer MA, Kang AH. Collagen-induced arthritis, an animal model of autoimmunity. Life Sci 1997; 61:1861-78.
2. Cremer MA, Kang AH. Collagen-induced arthritis in rodents: a review of immunity to type II collagen with emphasis on the importance of molecular conformation and structure. Int Rev Immunol 1988; 4:65-81.
3. Stuart JM, Townes AS. Kang AH. Collagen autoimmune arthritis. Annu Rev Immunol 1984; 2:199-218.
4. Holmdahl R, Andersson M, Goldschmidt TJ, Gustafsson K, Jansson L, Mo JA. Type II collagen autoimmunity in animals and provocations leading to arthritis. Immunol Rev 1990; 118:193-232.
5. Cremer MA, Rosloniec EF, Kang AH. The cartilage collagens: a review of their structure, organization, and role in the pathogenesis of experimental arthritis in animals and in human rheumatic disease. J Mol Med 1998; 76:275-238.
6. Miyahara H, Myers L, Terato K, Seyer J, Stuart J, Kang A. Identification and characterization of a major tolerogenic T cell epitope of type II collagen which suppresses arthritis in B10.RIII mice. Immunology 1995; 86:110-5.
7. r): localization of an arthritogenic determinant to a fragment of the type II collagen molecule. Immunology 1995; 84:509-13.
8. Tang B, Chiang TM. Brand DD, Gumanovskaya ML, Stuart JM. Kang AH. Myers LK. Molecular definition and characterization of recombinant bovine CB8 and CB10: immunogenicity and arthritogenicity. Clin Immunol 1999; 92:255-64.
9. Tang B, Brand DD. Chiang TM. Stuart JM, Kang AH, Myers LK. Immunogenicity and arthritogenicity of recombinant CB10 in B10.RIII mice. J Immunol 2000; 164:481-7.
10. Wooley PH, Luthra HS, Stuart JM, David CS. Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates. J Exp Med 1981; 154:688-700.
11. Wang W, Malcolm BA. Two-stage PCR protocol allowing introduction of multiple mutations, deletions and insertions using QuikChange site-directed mutagenesis. Biotechniques 1999; 26:680-2.
12. Tang B, Mano H, Yi T. Ihle J. Tec kinase associates with c-kit and is tyrosine phosphorylated and activated following stem cell factor binding. Mol Cell Biol 1994; 14:8432-7.
13. Rosloniec EF. Kang AH, Myers LK. Cremer MA. Collagen-induced arthritis. In; Coico R. Shevach E, eds. Current Protocols in Immunology. New York, NY: Wiley & Sons, 1997: 15.5.1-24.
14. Cirrho TP, Pu Z, Deck MB, Unanue ER. Deamidation of asparagine in a major histocompatibility complex-bound peptide affects T cell recognition but does not explain type B reactivity. J Exp Med 2001; 194:1165-70.
15. Colledge L, Sun MY, Lin W, Blackburn CC, Reay PA. Differing processing requirements of four recombinant antigens containing a single defined T-cell epitope for presentation by major histocompatibility complex class II. Immunology 2001; 103:343-50.
16. Falk K, Rotzschke O, Santambrogio L, Dorf ME, Brosnan C, Strominger JL. Induction and suppression of an autoimmune disease by oligomerized T cell epitopes: enhanced in vivo potency of encephalitogenic peptides. J Exp Med 2000; 191: 717-30.
17. Cremer MA. Collagen-induced arthritis. In; R A A D, Greenwald H.S., eds. Handbook of Animal Models for the Rheumatic Diseases, Vol. I. Boca Raton, FL: CRC Press, 1988:17-27.
18. Myers LK, Brand DD, Ye XJ et al. Characterization of recombinant type II collagen: arthritogenicity and tolerogenicity in DBA/1 mice. Immunology 1998; 95:631-9.