Induction of A:T to G:C transition mutations by 5-(2-chloroethyl)-2′- deoxyuridine (CEDU), an antiviral pyrimidine nucleoside analogue, in the bone marrow of Muta™Mouse

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 568, Issue 2, 2004, Pages 211-220

  Staedtler, Frank ^a   Suter, Willi ^a   Martus, Hans Joerg ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

5 (2 Chloroethyl) 2 deoxyuridine (CEDU); A:T to G:C transition; Antiviral pyrimidine nucleoside analogue; Bacteriophage lambda lacZ transgenic Muta Mouse; DNA sequencing; mutation spectrum

Indexed keywords

5 (2 CHLOROETHYL) 2' DEOXYURIDINE; BETA GALACTOSIDASE;

AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; BONE MARROW; CONTROLLED STUDY; DNA REPLICATION; DNA SEQUENCE; DNA STRAND; GENE MUTATION; INDUCED MUTATION; MOUSE; MUTAGENICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; REVERTANT; TRANSGENIC MOUSE;

ANIMALS; ANTIVIRAL AGENTS; BASE COMPOSITION; BASE SEQUENCE; BONE MARROW CELLS; DEOXYURIDINE; DNA MUTATIONAL ANALYSIS; DNA PRIMERS; DNA REPAIR; LAC OPERON; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTATION; SEQUENCE ANALYSIS, DNA;

ANIMALIA; BACTERIOPHAGE LAMBDA; MUS MUSCULUS; SALMONELLA; SIMPLEXVIRUS;

EID: 8144229162     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2004.08.014     Document Type: Article

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