-
1
-
-
49149127016
-
Models of tibial fracture healing in normal and Nf1-deficient mice
-
Schindeler A., Morse A., Harry L., Godfrey C., Mikulec K., McDonald M., et al. Models of tibial fracture healing in normal and Nf1-deficient mice. J Orthop Res 2008, 26:1053-1060.
-
(2008)
J Orthop Res
, vol.26
, pp. 1053-1060
-
-
Schindeler, A.1
Morse, A.2
Harry, L.3
Godfrey, C.4
Mikulec, K.5
McDonald, M.6
-
2
-
-
33750580557
-
Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions
-
Yang F.C., Chen S., Robling A.G., Yu X., Nebesio T.D., Yan J., et al. Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions. J Clin Invest 2006, 116:2880-2891.
-
(2006)
J Clin Invest
, vol.116
, pp. 2880-2891
-
-
Yang, F.C.1
Chen, S.2
Robling, A.G.3
Yu, X.4
Nebesio, T.D.5
Yan, J.6
-
3
-
-
38049043427
-
Modeling bone morphogenetic protein and bisphosphonate combination therapy in wild-type and Nf1 haploinsufficient mice
-
Schindeler A., Ramachandran M., Godfrey C., Morse A., McDonald M., Mikulec K., et al. Modeling bone morphogenetic protein and bisphosphonate combination therapy in wild-type and Nf1 haploinsufficient mice. J Orthop Res 2008, 26:65-74.
-
(2008)
J Orthop Res
, vol.26
, pp. 65-74
-
-
Schindeler, A.1
Ramachandran, M.2
Godfrey, C.3
Morse, A.4
McDonald, M.5
Mikulec, K.6
-
4
-
-
7344222073
-
Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1
-
Klose A., Ahmadian M.R., Schuelke M., Scheffzek K., Hoffmeyer S., Gewies A., et al. Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1. Hum Mol Genet 1998, 7:1261-1268.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1261-1268
-
-
Klose, A.1
Ahmadian, M.R.2
Schuelke, M.3
Scheffzek, K.4
Hoffmeyer, S.5
Gewies, A.6
-
5
-
-
33344474975
-
NF1 gene expression in mouse fracture healing and in experimental rat pseudarthrosis
-
Kuorilehto T., Ekholm E., Nissinen M., Hietaniemi K., Hiltunen A., Paavolainen P., et al. NF1 gene expression in mouse fracture healing and in experimental rat pseudarthrosis. J Histochem Cytochem 2006, 54:363-370.
-
(2006)
J Histochem Cytochem
, vol.54
, pp. 363-370
-
-
Kuorilehto, T.1
Ekholm, E.2
Nissinen, M.3
Hietaniemi, K.4
Hiltunen, A.5
Paavolainen, P.6
-
6
-
-
0142027643
-
Role of osteoclast extracellular signal-regulated kinase (ERK) in cell survival and maintenance of cell polarity
-
Nakamura H., Hirata A., Tsuji T., Yamamoto T. Role of osteoclast extracellular signal-regulated kinase (ERK) in cell survival and maintenance of cell polarity. J Bone Miner Res 2003, 18:1198-1205.
-
(2003)
J Bone Miner Res
, vol.18
, pp. 1198-1205
-
-
Nakamura, H.1
Hirata, A.2
Tsuji, T.3
Yamamoto, T.4
-
7
-
-
33748028794
-
Ras-MAPK signaling in osteogenic differentiation: friend or foe?
-
Schindeler A., Little D.G. Ras-MAPK signaling in osteogenic differentiation: friend or foe?. J Bone Miner Res 2006, 21:1331-1338.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 1331-1338
-
-
Schindeler, A.1
Little, D.G.2
-
8
-
-
57749108178
-
Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation
-
Daginakatte G.C., Gianino S.M., Zhao N.W., Parsadanian A.S., Gutmann D.H. Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation. Cancer Res 2008, 68:10358-10366.
-
(2008)
Cancer Res
, vol.68
, pp. 10358-10366
-
-
Daginakatte, G.C.1
Gianino, S.M.2
Zhao, N.W.3
Parsadanian, A.S.4
Gutmann, D.H.5
-
9
-
-
0028349997
-
Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues
-
Brannan C.I., Perkins A.S., Vogel K.S., Ratner N., Nordlund M.L., Reid S.W., et al. Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes Dev 1994, 8:1019-1029.
-
(1994)
Genes Dev
, vol.8
, pp. 1019-1029
-
-
Brannan, C.I.1
Perkins, A.S.2
Vogel, K.S.3
Ratner, N.4
Nordlund, M.L.5
Reid, S.W.6
-
10
-
-
0035312367
-
Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain
-
Zhu Y., Romero M.I., Ghosh P., Ye Z., Charnay P., Rushing E.J., et al. Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain. Genes Dev 2001, 15:859-876.
-
(2001)
Genes Dev
, vol.15
, pp. 859-876
-
-
Zhu, Y.1
Romero, M.I.2
Ghosh, P.3
Ye, Z.4
Charnay, P.5
Rushing, E.J.6
-
11
-
-
0027946689
-
Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage
-
Katagiri T., Yamaguchi A., Komaki M., Abe E., Takahashi N., Ikeda T., et al. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J Cell Biol 1994, 127:1755-1766.
-
(1994)
J Cell Biol
, vol.127
, pp. 1755-1766
-
-
Katagiri, T.1
Yamaguchi, A.2
Komaki, M.3
Abe, E.4
Takahashi, N.5
Ikeda, T.6
-
12
-
-
77952696475
-
Rapid cell culture and pre-clinical screening of a transforming growth factor-beta (TGF-beta) inhibitor for orthopaedics
-
Schindeler A., Morse A., Peacock L., Mikulec K., Yu N.Y., Liu R., et al. Rapid cell culture and pre-clinical screening of a transforming growth factor-beta (TGF-beta) inhibitor for orthopaedics. BMC Musculoskelet Disord 2010, 11:105.
-
(2010)
BMC Musculoskelet Disord
, vol.11
, pp. 105
-
-
Schindeler, A.1
Morse, A.2
Peacock, L.3
Mikulec, K.4
Yu, N.Y.5
Liu, R.6
-
13
-
-
27744457043
-
Osteoclasts but not osteoblasts are affected by a calcified surface treated with zoledronic acid in vitro
-
Schindeler A., Little D.G. Osteoclasts but not osteoblasts are affected by a calcified surface treated with zoledronic acid in vitro. Biochem Biophys Res Commun 2005, 338:710-716.
-
(2005)
Biochem Biophys Res Commun
, vol.338
, pp. 710-716
-
-
Schindeler, A.1
Little, D.G.2
-
14
-
-
33748856374
-
Efficient adenoviral-mediated gene delivery into porcine mesenchymal stem cells
-
Bosch P., Fouletier-Dilling C., Olmsted-Davis E.A., Davis A.R., Stice S.L. Efficient adenoviral-mediated gene delivery into porcine mesenchymal stem cells. Mol Reprod Dev 2006, 73:1393-1403.
-
(2006)
Mol Reprod Dev
, vol.73
, pp. 1393-1403
-
-
Bosch, P.1
Fouletier-Dilling, C.2
Olmsted-Davis, E.A.3
Davis, A.R.4
Stice, S.L.5
-
15
-
-
29344435159
-
Dimethyl sulfoxide as an inducer of differentiation in preosteoblast MC3T3-E1 cells
-
Cheung W.M., Ng W.W., Kung A.W. Dimethyl sulfoxide as an inducer of differentiation in preosteoblast MC3T3-E1 cells. FEBS Lett 2006, 580:121-126.
-
(2006)
FEBS Lett
, vol.580
, pp. 121-126
-
-
Cheung, W.M.1
Ng, W.W.2
Kung, A.W.3
-
16
-
-
61849095684
-
JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation
-
Matsuguchi T., Chiba N., Bandow K., Kakimoto K., Masuda A., Ohnishi T. JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation. J Bone Miner Res 2009, 24:398-410.
-
(2009)
J Bone Miner Res
, vol.24
, pp. 398-410
-
-
Matsuguchi, T.1
Chiba, N.2
Bandow, K.3
Kakimoto, K.4
Masuda, A.5
Ohnishi, T.6
-
17
-
-
0037013229
-
Signal transductions induced by bone morphogenetic protein-2 and transforming growth factor-beta in normal human osteoblastic cells
-
Lai C.F., Cheng S.L. Signal transductions induced by bone morphogenetic protein-2 and transforming growth factor-beta in normal human osteoblastic cells. J Biol Chem 2002, 277:15514-15522.
-
(2002)
J Biol Chem
, vol.277
, pp. 15514-15522
-
-
Lai, C.F.1
Cheng, S.L.2
-
18
-
-
40849135622
-
Recent insights into bone development, homeostasis, and repair in type 1 neurofibromatosis (NF1)
-
Schindeler A., Little D.G. Recent insights into bone development, homeostasis, and repair in type 1 neurofibromatosis (NF1). Bone 2008, 42:616-622.
-
(2008)
Bone
, vol.42
, pp. 616-622
-
-
Schindeler, A.1
Little, D.G.2
-
19
-
-
20944447547
-
Neurofibromin and its inactivation of Ras are prerequisites for osteoblast functioning
-
Yu X., Chen S., Potter O.L., Murthy S.M., Li J., Pulcini J.M., et al. Neurofibromin and its inactivation of Ras are prerequisites for osteoblast functioning. Bone 2005, 36:793-802.
-
(2005)
Bone
, vol.36
, pp. 793-802
-
-
Yu, X.1
Chen, S.2
Potter, O.L.3
Murthy, S.M.4
Li, J.5
Pulcini, J.M.6
-
20
-
-
33751412300
-
ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae
-
Elefteriou F., Benson M.D., Sowa H., Starbuck M., Liu X., Ron D., et al. ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metab 2006, 4:441-451.
-
(2006)
Cell Metab
, vol.4
, pp. 441-451
-
-
Elefteriou, F.1
Benson, M.D.2
Sowa, H.3
Starbuck, M.4
Liu, X.5
Ron, D.6
-
21
-
-
0033799930
-
Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma
-
Lau N., Feldkamp M.M., Roncari L., Loehr A.H., Shannon P., Gutmann D.H., et al. Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma. J Neuropathol Exp Neurol 2000, 59:759-767.
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, pp. 759-767
-
-
Lau, N.1
Feldkamp, M.M.2
Roncari, L.3
Loehr, A.H.4
Shannon, P.5
Gutmann, D.H.6
-
22
-
-
9044251606
-
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells
-
Bollag G., Clapp D.W., Shih S., Adler F., Zhang Y.Y., Thompson P., et al. Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells. Nat Genet 1996, 12:144-148.
-
(1996)
Nat Genet
, vol.12
, pp. 144-148
-
-
Bollag, G.1
Clapp, D.W.2
Shih, S.3
Adler, F.4
Zhang, Y.Y.5
Thompson, P.6
-
23
-
-
0034730635
-
Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts
-
Sherman L.S., Atit R., Rosenbaum T., Cox A.D., Ratner N. Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts. J Biol Chem 2000, 275:30740-30745.
-
(2000)
J Biol Chem
, vol.275
, pp. 30740-30745
-
-
Sherman, L.S.1
Atit, R.2
Rosenbaum, T.3
Cox, A.D.4
Ratner, N.5
-
24
-
-
0030045594
-
Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia
-
Largaespada D.A., Brannan C.I., Jenkins N.A., Copeland N.G. Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia. Nat Genet 1996, 12:137-143.
-
(1996)
Nat Genet
, vol.12
, pp. 137-143
-
-
Largaespada, D.A.1
Brannan, C.I.2
Jenkins, N.A.3
Copeland, N.G.4
-
25
-
-
34447328431
-
Multiple roles for neurofibromin in skeletal development and growth
-
Kolanczyk M., Kossler N., Kuhnisch J., Lavitas L., Stricker S., Wilkening U., et al. Multiple roles for neurofibromin in skeletal development and growth. Hum Mol Genet 2007, 16:874-886.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 874-886
-
-
Kolanczyk, M.1
Kossler, N.2
Kuhnisch, J.3
Lavitas, L.4
Stricker, S.5
Wilkening, U.6
-
26
-
-
41149133470
-
Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1
-
Yan J., Chen S., Zhang Y., Li X., Li Y., Wu X., et al. Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1. Hum Mol Genet 2008, 17:936-948.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 936-948
-
-
Yan, J.1
Chen, S.2
Zhang, Y.3
Li, X.4
Li, Y.5
Wu, X.6
-
27
-
-
72149091706
-
M-Ras is activated by bone morphogenetic protein-2 and participates in osteoblastic determination, differentiation, and transdifferentiation
-
Watanabe-Takano H., Takano K., Keduka E., Endo T. M-Ras is activated by bone morphogenetic protein-2 and participates in osteoblastic determination, differentiation, and transdifferentiation. Exp Cell Res 2009, 316:477-490.
-
(2009)
Exp Cell Res
, vol.316
, pp. 477-490
-
-
Watanabe-Takano, H.1
Takano, K.2
Keduka, E.3
Endo, T.4
-
28
-
-
79955631436
-
Activation of c-Jun NH(2)-terminal kinase 1 increases cellular responsiveness to BMP-2 and decreases binding of inhibitory Smad6 to the type 1 BMP receptor
-
Liu H., Liu Y., Viggeswarapu M., Zheng Z., Titus L., Boden S.D. Activation of c-Jun NH(2)-terminal kinase 1 increases cellular responsiveness to BMP-2 and decreases binding of inhibitory Smad6 to the type 1 BMP receptor. J Bone Miner Res 2011, 26:1122-1132.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 1122-1132
-
-
Liu, H.1
Liu, Y.2
Viggeswarapu, M.3
Zheng, Z.4
Titus, L.5
Boden, S.D.6
-
29
-
-
0033547411
-
Serial passage of MC3T3-E1 cells alters osteoblastic function and responsiveness to transforming growth factor-beta1 and bone morphogenetic protein-2
-
Chung C.Y., Iida-Klein A., Wyatt L.E., Rudkin G.H., Ishida K., Yamaguchi D.T., et al. Serial passage of MC3T3-E1 cells alters osteoblastic function and responsiveness to transforming growth factor-beta1 and bone morphogenetic protein-2. Biochem Biophys Res Commun 1999, 265:246-251.
-
(1999)
Biochem Biophys Res Commun
, vol.265
, pp. 246-251
-
-
Chung, C.Y.1
Iida-Klein, A.2
Wyatt, L.E.3
Rudkin, G.H.4
Ishida, K.5
Yamaguchi, D.T.6
-
30
-
-
33745259022
-
Double inactivation of NF1 in tibial pseudarthrosis
-
Stevenson D.A., Zhou H., Ashrafi S., Messiaen L.M., Carey J.C., D'Astous J.L., et al. Double inactivation of NF1 in tibial pseudarthrosis. Am J Hum Genet 2006, 79:143-148.
-
(2006)
Am J Hum Genet
, vol.79
, pp. 143-148
-
-
Stevenson, D.A.1
Zhou, H.2
Ashrafi, S.3
Messiaen, L.M.4
Carey, J.C.5
D'Astous, J.L.6
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