Chronic Δ-9-tetrahydrocannabinol administration increases lymphocyte CXCR4 expression in rhesus macaques

Journal of Neuroimmune Pharmacology

Volumn 6, Issue 4, 2011, Pages 540-545

  Lecapitaine, Nicole J ^a   Zhang, Ping ^b   Winsauer, Peter ^a   Walker, Edith ^a   Vande Stouwe, Curtis ^a   Porretta, Constance ^a   Molina, Patricia E ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Cannabinoids; CXCR4; Flow cytometry; Lymphocytes; Rhesus macaques

Indexed keywords

CELL MARKER; CHEMOKINE RECEPTOR CXCR4; TETRAHYDROCANNABINOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; IMMUNOMODULATION; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MALE; MEMORY T LYMPHOCYTE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RETROVIRUS INFECTION; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; FLOW CYTOMETRY; MACACA MULATTA; MALE; RECEPTORS, CXCR4; TETRAHYDROCANNABINOL;

EID: 81355138968     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-011-9277-4     Document Type: Article

References (25)

1. CC Bleul L Wu JA Hoxie TA Springer CR Mackay 1997 The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes Proc Natl Acad Sci 94 5 1925 1930 9050881 10.1073/pnas.94.5.1925 1:CAS:528:DyaK2sXhslensLc%3D (Pubitemid 27113938)
2. C Borner M Smida V Hollt B Schraven J Kraus 2009 Cannabinoid receptor type 1- and 2-mediated increase in cyclic AMP inhibits T cell receptor-triggered signaling J Biol Chem 284 35450 35460 19858202 10.1074/jbc.M109.006338
3. R Condie A Herring WS Koh M Lee NE Kaminski 1996 Cannabinoid inhibition of adenylate cyclase-mediated signal transduction and interleukin 2 (IL-2) expression in the murine T-cell line, EL4.IL-2 J Biol Chem 271 22 13175 13183 8662742 10.1074/jbc.271.22.13175 1:CAS:528:DyaK28XjtlGisL0%3D (Pubitemid 26175897)
4. AD Cristillo HC Highbarger RL Dewar DS Dimitrov H Golding BE Bierer 2002 Up-regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP-responsive element FASEB J 16 354 364 11874984 10.1096/fj.01-0744com 1:CAS:528:DC%2BD38XhvVCmtL4%3D (Pubitemid 34195296)
5. ML Dion JF Poulin R Bordi M Sylvestre R Corsini N Kettaf A Dalloul MR Boulassel P Debre JP Routy Z Grossman RP Sekaly R Cheynier 2004 HIV infection rapidly induces and maintains a substantial suppression of thymocyte proliferation Immunity 21 757 768 15589165 10.1016/j.immuni.2004.10.013 1:CAS:528:DC%2BD2MXjvFCquw%3D%3D (Pubitemid 39626667)
6. W Jia VL Hegde NP Singh D Sisco S Grant M Nagarkatti PS Nagarkatti 2006 D9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria Mol Cancer Res 4 8 549 562 16908594 10.1158/1541-7786.MCR-05-0193 1:CAS:528:DC%2BD28XotV2rt7g%3D (Pubitemid 44341365)
7. Y Kawakami TW Klein C Newton JY Djeu G Dennert S Specter H Friedman 1988 Suppression by cannabinoids of a cloned cell line with natural killer cell activity Proc Soc Exp Biol Med 187 3 355 359 2831542 1:CAS:528: DyaL1cXhs1WisLk%3D (Pubitemid 18090794)
8. TW Klein C Newton K Larsen L Lu I Perkins L Nong H Friedman 2003 The cannabinoid system and immune modulation J Leukoc Biol 74 4 486 496 12960289 10.1189/jlb.0303101 1:CAS:528:DC%2BD3sXotlGktLo%3D (Pubitemid 38040375)
9. R Kurihara Y Tohyama S Matsusaka H Naruse E Kinoshita T Tsujioka Y Katsumata H Yamamura 2006 Effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like HL60 cells and human neutrophils J Biol Chem 281 18 12908 12918 16513651 10.1074/jbc.M510871200 1:CAS:528:DC%2BD28XjvFKktbk%3D (Pubitemid 43855384)
10. PE Molina P Winsauer P Zhang E Walker L Birke AM Amedee C Vande Stouwe D Troxclair R McGoey K Varner L Byerley L Lamotte 2010 Cannabinoid administration attenuates the progression of simian immunodeficiency virus AIDS Res Hum Retrovir 10.1089/aid.2010.0218 20874519
11. S Murikinati E Juttler T Keinert DA Ridder S Muhammad Z Waibler C Ledent A Zimmer U Kalinke M Schwaninger 2010 Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment FASEB J 24 3 788 798 19884325 10.1096/fj.09-141275 1:CAS:528:DC%2BC3cXjtFagsbo%3D
12. GG Nahas A Moirishima B Desoize 1977 Effects of cannabinoids on macromolecular synthesis and replication of cultured lymphocytes Fed Proc 36 1748 1752 844617 1:CAS:528:DyaE2sXktVSitLg%3D (Pubitemid 8078416)
13. BH Petersen J Graham L Lemberger 1976 Marijuana, tetrahydrocannabinol and T-cell function Life Sci 19 395 400 1085394 10.1016/0024-3205(76)90044-8 1:CAS:528:DyaE28XltFKrurw%3D
14. R Phillips A Ager 2002 Activation of pertussis toxin-sensitive CXCL12 (SDF-1) receptors mediates transendothelial migration of T lymphocytes across lymph node high endothelial cells Eur J Immunol 32 3 837 847 11870628 10.1002/1521-4141(200203)32:3<837::AID-IMMU837>3.0.CO;2-Q 1:CAS:528:DC%2BD38Xitl2nsL0%3D (Pubitemid 34257561)
15. S Pross T Klein C Newton J Smith R Widen H Friedman 1990 Differential suppression of T-cell subpopulations by THC (delta-9-tetrahydrocannabinol) Int J Immunopharmacol 12 539 544 2170281 10.1016/0192-0561(90)90118-7 1:CAS:528:DyaK3cXls1Ggs70%3D (Pubitemid 20263600)
16. RB Rock G Gekker S Hu WS Sheng GA Cabral BR Martin 2007 WIN55,212-2-mediated inhibition of HIV-1 expression in microglial cells: involvement of cannabinoid receptors J Neuroimmune Pharmacol 2 178 183 18040842 10.1007/s11481-006-9040-4
17. S Sopper D Nierwetberg A Halbach U Sauer C Scheller C Stahl-Hennig K Matz-Rensing F Schafer T Schneider V ter Meulen JG Muller 2003 Impact of simian immunodeficiency virus (SIV) infection on lymphocyte numbers and T-cell turnover in different organs of rhesus monkeys Blood 101 1213 1219 12393472 10.1182/blood-2002-06-1644 1:CAS:528:DC%2BD3sXht1agt7Y%3D (Pubitemid 36182488)
18. H Schuitemaker M Koot NA Kootstra MW Dercksen RE deGoede RP van Steenwijk JM Lange JK Schattenkerk F Miedema M Tersmette 1992 Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell tropic virus populations J Virol 66 1354 1360 1738194 1:STN:280: DyaK387kvV2itQ%3D%3D
19. AH Shay R Choi K Whittaker K Salehi CM Kitchen DP Tashkin MD Roth CG Balwin 2003 Impairement of antimicrobial activity and nitric oxide production in alveolar macrophages from smokers of marijuana and cocaine J Infect Dis 187 4 700 704 12599091 10.1086/368370 1:CAS:528:DC%2BD3sXit1yhur4%3D (Pubitemid 36250038)
20. B Tindall DA Cooper B Donovan T Barnes CR Philpot J Gold R Penny 1988 The Sydney AIDS project: development of acquired immunodeficiency syndrome in a group of HIV seropositive homosexual men Aust N Z J Med 18 8 15 3395303 10.1111/j.1445-5994.1988.tb02232.x 1:STN:280:DyaL1c3otVKqtA%3D%3D
21. JM Wallace JS Oishi RG Barbers MS Simmons DP Tashkin 1994 Lymphocytic subpopulation profiles in bronchoalveolar lavage fluid and peripheral blood from tobacco and marijuana smokers Chest 105 847 852 7907538 10.1378/chest.105.3.847 1:STN:280:DyaK2c7nvVSitg%3D%3D (Pubitemid 24088468)
22. Winsauer PJ, Molina PE, Amedee AM, Filipeanu CM, McGoey RR, Troxclair DA, Walker EM, Birke LL, Vande Stouwe C, Howard JM, Leonard ST, Moerschbaecher JM, and Lewis PB (2011) Tolerance to chronic delta-9-tetrahydrocannabinol (Δ9-THC) in Rhesus Macaques infected with simian immunodeficiency virus. Exp and Clin Psychopharm (in press)
23. SC White SC Brin BW Janicki 1975 Mitogen-induced blastogenic responses of lymphocytes from marihuana smokers Science 188 71 72 1078732 10.1126/science.1078732 1:CAS:528:DyaE2MXhs1Gjs7k%3D
24. M Yuan S Kiertscher Q Cheng R Zoumalan D Tashkin M Roth 2002 Delta-9-tetrahydrocannabinol regulates Th1/Th2 cytokine balance in activated human T cells J Neuroimmunol 133 124 131 12446015 10.1016/S0165-5728(02)00370-3 1:CAS:528:DC%2BD38Xoslant7k%3D (Pubitemid 35346734)
25. W Zhu H Friedman TW Klein 1998 Δ9-Tetrahydrocannabinol induces apoptosis in macrophages and lymphocytes: involvement of Bcl-2 and caspase-1 J Pharmacol Exp Ther 286 1103 1109 9694974 1:CAS:528:DyaK1cXlsVWhtr4%3D (Pubitemid 29003509)