Update on the endoscopic management of peptic ulcer bleeding

Current Gastroenterology Reports

Volumn 13, Issue 6, 2011, Pages 525-531

  Holster, Ingrid Lisanne ^a   Kuipers, Ernst Johan ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Endoscopy; Management; Peptic ulcer; Pharmacotherapy; Review; Ulcer bleeding

Indexed keywords

ACETYLSALICYLIC ACID; ADRENALIN; ALCOHOL; CYCLOOXYGENASE 2 INHIBITOR; ENBUCRILATE; ETHANOLAMINE; FIBRIN GLUE; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; OXYGEN; PLACEBO; POLIDOCANOL; PROTON PUMP INHIBITOR;

ABLATION THERAPY; ARTERY EMBOLISM; ARTICLE; ARTIFICIAL EMBOLISM; BLEEDING DISORDER; CARDIOVASCULAR DISEASE; CLIP; CONTINUOUS INFUSION; DRUG FATALITY; DRUG MEGADOSE; DRUG WITHDRAWAL; ENDOSCOPIC THERAPY; ERYTHROCYTE TRANSFUSION; FLUID RESUSCITATION; GASTROINTESTINAL ENDOSCOPY; HELICOBACTER INFECTION; HEMOSPRAY; HIGH RISK PATIENT; HUMAN; HYPERTHERMIC THERAPY; INTERMETHOD COMPARISON; META ANALYSIS (TOPIC); OXYGEN THERAPY; PEPTIC ULCER BLEEDING; PERSISTENT REBLEEDING; RANDOMIZED CONTROLLED TRIAL (TOPIC); RISK BENEFIT ANALYSIS; UNSPECIFIED SIDE EFFECT;

ENDOSCOPY, GASTROINTESTINAL; ERYTHROCYTE TRANSFUSION; FLUID THERAPY; HEMOSTASIS, ENDOSCOPIC; HUMANS; PEPTIC ULCER HEMORRHAGE; PROTON PUMP INHIBITORS;

EID: 81255212017     PISSN: 15228037     EISSN: 1534312X     Source Type: Journal    
DOI: 10.1007/s11894-011-0223-7     Document Type: Article

References (39)

1. ME van Leerdam EM Vreeburg EA Rauws, et al. 2003 Acute upper GI bleeding: did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993/1994 and 2000 Am J Gastroenterol 98 1494 9 12873568 10.1111/j.1572-0241.2003.07517.x (Pubitemid 36875338)
2. F Di Fiore S Lecleire V Merle, et al. 2005 Changes in characteristics and outcome of acute upper gastrointestinal haemorrhage: a comparison of epidemiology and practices between 1996 and 2000 in a multicentre French study Eur J Gastroenterol Hepatol 17 641 7 15879726 10.1097/00042737-200506000-00008 (Pubitemid 40733811)
3. GJ Theocharis KC Thomopoulos G Sakellaropoulos, et al. 2008 Changing trends in the epidemiology and clinical outcome of acute upper gastrointestinal bleeding in a defined geographical area in Greece J Clin Gastroenterol 42 128 33 18209579 10.1097/01.mcg.0000248004.73075.ad
4. SA Hearnshaw RF Logan D Lowe, et al. 2010 Use of endoscopy for management of acute upper gastrointestinal bleeding in the UK: results of a nationwide audit Gut 59 1022 1029 20357318 10.1136/gut.2008.174599 This nationwide UK audit provides important information on the epidemiology of upper gastrointestinal bleeding, the use of endoscopy and other interventions, and outcome with comparisons with published standards. One of the striking findings was the underuse of early endoscopy in patients at high risk of rebleeding. In this group, only 74% received endoscopy during admission, and only 50% underwent endoscopy within the recommended 24 hrs.
5. P Czernichow P Hochain JB Nousbaum, et al. 2000 Epidemiology and course of acute upper gastro-intestinal haemorrhage in four French geographical areas Eur J Gastroenterol Hepatol 12 175 81 10741931 10.1097/00042737-200012020-00007 1:STN:280:DC%2BD3c3gtl2ktw%3D%3D (Pubitemid 30166682)
6. GA Paspatis E Matrella A Kapsoritakis, et al. 2000 An epidemiological study of acute upper gastrointestinal bleeding in Crete, Greece Eur J Gastroenterol Hepatol 12 1215 20 11111778 10.1097/00042737-200012110-00008 1:STN:280:DC%2BD3M7ovVCmuw%3D%3D
7. Jairath V, Hearnshaw S, Brunskill SJ, et al.: Red cell transfusion for the management of upper gastrointestinal haemorrhage. Cochrane Database Syst Rev. 2010:CD006613.
8. SA Hearnshaw RF Logan KR Palmer, et al. 2010 Outcomes following early red blood cell transfusion in acute upper gastrointestinal bleeding Aliment Pharmacol Ther 32 215 24 20456308 10.1111/j.1365-2036.2010.04348.x 1:CAS:528:DC%2BC3cXpslWlsLc%3D
9. JY Lau WK Leung JC Wu, et al. 2007 Omeprazole before endoscopy in patients with gastrointestinal bleeding N Engl J Med 356 1631 40 17442905 10.1056/NEJMoa065703 1:CAS:528:DC%2BD2sXksFCmtLw%3D (Pubitemid 46631672)
10. AN Barkun M Bardou EJ Kuipers, et al. 2010 International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding Ann Intern Med 152 101 113 20083829 This paper published by an international consensus group is of outstanding importance because it provides widely endorsed consensus recommendations on the management of patients with non-variceal upper gastrointestinal bleeding. Similarly important is alike consensus of the Asia-Pacific Working Group which allows for the specific needs of resource-limited countries and ethnic differences in the Asia-Pacific region [29]
11. TA Rockall RF Logan HB Devlin, et al. 1996 Risk assessment after acute upper gastrointestinal haemorrhage Gut 38 316 21 8675081 10.1136/gut.38.3.316 1:STN:280:DyaK283ks12hsQ%3D%3D (Pubitemid 26074312)
12. O Blatchford WR Murray M Blatchford 2000 A risk score to predict need for treatment for upper-gastrointestinal haemorrhage Lancet 356 1318 21 11073021 10.1016/S0140-6736(00)02816-6 1:STN:280:DC%2BD3crhsVSluw%3D%3D
13. SH Pang JY Ching JY Lau, et al. 2010 Comparing the Blatchford and pre-endoscopic Rockall score in predicting the need for endoscopic therapy in patients with upper GI hemorrhage Gastrointest Endosc 71 1134 40 20598244 10.1016/j.gie.2010.01.028
14. GM Schacher D Lesbros-Pantoflickova MA Ortner, et al. 2005 Is early endoscopy in the emergency room beneficial in patients with bleeding peptic ulcer? A "fortuitously controlled" study Endoscopy 37 324 8 15824941 10.1055/s-2004-826237 1:STN:280:DC%2BD2M7ptVertg%3D%3D (Pubitemid 40561654)
15. LE Targownik S Murthy L Keyvani, et al. 2007 The role of rapid endoscopy for high-risk patients with acute nonvariceal upper gastrointestinal bleeding Can J Gastroenterol 21 425 9 17637943 (Pubitemid 47315457)
16. MS Cappell 2010 Medscape. Therapeutic endoscopy for acute upper gastrointestinal bleeding Nat Rev Gastroenterol Hepatol 7 214 29 20212504 10.1038/nrgastro.2010.24
17. CJ Kahi DM Jensen JJ Sung, et al. 2005 Endoscopic therapy versus medical therapy for bleeding peptic ulcer with adherent clot: A meta-analysis Gastroenterology 129 855 62 16143125 10.1053/j.gastro.2005.06.070 (Pubitemid 41242678)
18. Laine L: Systematic review of endoscopic therapy for ulcers with clots: Can a meta-analysis be misleading? Gastroenterology. 2005, 129:2127; author reply 2127-2128.
19. L Laine KR McQuaid 2009 Endoscopic therapy for bleeding ulcers: an evidence-based approach based on meta-analyses of randomized controlled trials Clin Gastroenterol Hepatol 7 33 47 18986845 10.1016/j.cgh.2008.08.016 quiz 31-32. This meta-analysis is the largest of five recent meta-analyses comparing endoscopic techniques for treatment of peptic ulcer bleeding (Table 1) and in addition also compares different pharmacotherapeutic regimens after endoscopic hemostatic therapy. Recommendations following these meta-analyses were valuable for the development of international guidelines
20. SC Chung HT Leong AC Chan, et al. 1996 Epinephrine or epinephrine plus alcohol for injection of bleeding ulcers: a prospective randomized trial Gastrointest Endosc 43 591 5 8781939 10.1016/S0016-5107(96)70197-9 1:STN:280:DyaK28znsFKmsg%3D%3D (Pubitemid 26192229)
21. P Rutgeerts E Rauws P Wara, et al. 1997 Randomised trial of single and repeated fibrin glue compared with injection of polidocanol in treatment of bleeding peptic ulcer Lancet 350 692 6 9291903 10.1016/S0140-6736(97)03233-9 1:CAS:528:DyaK2sXmt1Oqsbw%3D (Pubitemid 27371167)
22. K Kurokohchi T Maeta T Ohgi, et al. 2007 Successful treatment of a giant exposed blood vessel in a gastric ulcer by endoscopic sclerotherapy with N-butyl-2-cyanoacrylate Endoscopy 39 Suppl 1 E250 17957633 10.1055/s-2007-967012
23. R Marmo G Rotondano R Piscopo, et al. 2007 Dual therapy versus monotherapy in the endoscopic treatment of high-risk bleeding ulcers: a meta-analysis of controlled trials Am J Gastroenterol 102 279 289 17311650 10.1111/j.1572-0241.2006.01023.x quiz 469 (Pubitemid 46160541)
24. JJ Sung KK Tsoi LH Lai, et al. 2007 Endoscopic clipping versus injection and thermo-coagulation in the treatment of non-variceal upper gastrointestinal bleeding: a meta-analysis Gut 56 1364 73 17566018 10.1136/gut.2007.123976 (Pubitemid 47517828)
25. AN Barkun M Martel Y Toubouti, et al. 2009 Endoscopic hemostasis in peptic ulcer bleeding for patients with high-risk lesions: a series of meta-analyses Gastrointest Endosc 69 786 99 19152905 10.1016/j.gie.2008.05.031
26. Y Yuan C Wang RH Hunt 2008 Endoscopic clipping for acute nonvariceal upper-GI bleeding: a meta-analysis and critical appraisal of randomized controlled trials Gastrointest Endosc 68 339 51 18656600 10.1016/j.gie.2008.03. 1122 (Pubitemid 352010298)
27. HJ Lin CL Perng IC Sun, et al. 2003 Endoscopic haemoclip versus heater probe thermocoagulation plus hypertonic saline-epinephrine injection for peptic ulcer bleeding Dig Liver Dis 35 898 902 14703887 10.1016/j.dld.2003.07.006 1:STN:280:DC%2BD2c%2Fgs1yisA%3D%3D (Pubitemid 41070497)
28. JJ Sung D Luo JC Wu, et al. 2011 Early clinical experience of the safety and effectiveness of Hemospray in achieving hemostasis in patients with acute peptic ulcer bleeding Endoscopy 43 291 295 21455870 10.1055/s-0030-1256311 1:STN:280:DC%2BC3MzosFSkug%3D%3D
29. Sung JJ, Chan FK, Chen M, et al.: Asia-Pacific Working Group consensus on non-variceal upper gastrointestinal bleeding. Gut. 2011.
30. PW Chiu HK Joeng CL Choi, et al. 2006 Predictors of peptic ulcer rebleeding after scheduled second endoscopy: clinical or endoscopic factors? Endoscopy 38 726 9 16810597 10.1055/s-2006-925179 1:STN:280: DC%2BD28zptFOmsg%3D%3D (Pubitemid 44044402)
31. C Ripoll R Banares I Beceiro, et al. 2004 Comparison of transcatheter arterial embolization and surgery for treatment of bleeding peptic ulcer after endoscopic treatment failure J Vasc Interv Radiol 15 447 50 15126653 (Pubitemid 38590867)
32. GI Leontiadis VK Sharma CW Howden 2005 Systematic review and meta-analysis: enhanced efficacy of proton-pump inhibitor therapy for peptic ulcer bleeding in Asia-a post hoc analysis from the Cochrane Collaboration Aliment Pharmacol Ther 21 1055 61 15854166 10.1111/j.1365-2036.2005.02441.x 1:CAS:528:DC%2BD2MXltVWktb0%3D (Pubitemid 40646530)
33. JJ Sung A Barkun EJ Kuipers, et al. 2009 Intravenous esomeprazole for prevention of recurrent peptic ulcer bleeding: a randomized trial Ann Intern Med 150 455 64 19221370
34. JP Gisbert S Khorrami F Carballo, et al. 2004 Meta-analysis: Helicobacter pylori eradication therapy vs. antisecretory non-eradication therapy for the prevention of recurrent bleeding from peptic ulcer Aliment Pharmacol Ther 19 617 629 15023164 10.1111/j.1365-2036.2004.01898.x 1:CAS:528:DC%2BD2cXjslyhurs%3D (Pubitemid 38445423)
35. FK Chan VW Wong BY Suen, et al. 2007 Combination of a cyclo-oxygenase-2 inhibitor and a proton-pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a double-blind, randomised trial Lancet 369 1621 6 17499604 10.1016/S0140-6736(07)60749-1 1:CAS:528:DC%2BD2sXltF2qsrY%3D (Pubitemid 46710125)
36. EM van Soest MC Sturkenboom JP Dieleman, et al. 2007 Adherence to gastroprotection and the risk of NSAID-related upper gastrointestinal ulcers and haemorrhage Aliment Pharmacol Ther 26 265 75 17593072 10.1111/j.1365-2036.2007. 03358.x (Pubitemid 46985490)
37. van Soest EM, Valkhoff VE, Mazzaglia G, et al.: Suboptimal gastroprotective coverage of NSAID use and the risk of upper gastrointestinal bleeding and ulcers: an observational study using three European databases. Gut. 2011, In press
38. JJ Sung JY Lau JY Ching, et al. 2009 Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trial Ann Intern Med 152 1 9 19949136
39. GL Wong VW Wong Y Chan, et al. 2009 High incidence of mortality and recurrent bleeding in patients with Helicobacter pylori-negative idiopathic bleeding ulcers Gastroenterology 137 525 31 19445937 10.1053/j.gastro.2009.05. 006