Ultrasound and microbubble-assisted gene delivery in Achilles tendons: Long lasting gene expression and restoration of fibromodulin KO phenotype

Journal of Controlled Release

Volumn 156, Issue 2, 2011, Pages 223-230

  Delalande, Anthony ^a,b   Bouakaz, Ayache ^b   Renault, Gilles ^c,d   Tabareau, Flore ^e   Kotopoulis, Spiros ^f   Midoux, Patrick ^a   Arbeille, Brigitte ^b   Uzbekov, Rustem ^b,g   Chakravarti, Shukti ^h   Postema, Michiel ⁱ   Pichon, Chantal ^a  

^a CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

^b UNIVERSITÉ DE TOURS   (France)

^c INSTITUT COCHIN   (France)

^d INSERM   (France)

^e CENTRE HOSPITALIER RÉGIONAL D ORLÉANS   (France)

^f UNIVERSITY OF HULL   (United Kingdom)

^g MOSCOW STATE UNIVERSITY   (Russian Federation)

^h JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ UNIVERSITY OF BERGEN   (Norway)

Author keywords

Gene delivery; Sonoporation; Tendon

Indexed keywords

ACHILLES TENDONS; CLINICAL APPLICATION; COLLAGEN FIBRILS; DIAMETER DISTRIBUTIONS; DUTY CYCLES; E. COLI; GENE DELIVERY; LONG LASTING; LUCIFERASE EXPRESSION; LUCIFERASE GENES; MICROBUBBLES; PLASMID ENCODING; PROTEIN EXPRESSIONS; QUANTITATIVE PCR; SONOPORATION; TRANSGENE; ULTRASTRUCTURAL ANALYSIS; WILD TYPES;

DNA; ESCHERICHIA COLI; GENE ENCODING; GENE THERAPY; GENE TRANSFER; MAMMALS; POLYMERASE CHAIN REACTION; RESTORATION; TENDONS; ULTRASONICS;

GENE EXPRESSION;

COLLAGEN; FIBROMODULIN; LUCIFERASE; PLASMID DNA;

ACHILLES TENDON; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ESCHERICHIA COLI; GENE EXPRESSION; MICROBUBBLE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; ULTRASOUND;

ACHILLES TENDON; ANIMALS; DNA; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; LUCIFERASES; MICE; MICE, KNOCKOUT; MICROBUBBLES; PHENOTYPE; PLASMIDS; PROTEOGLYCANS; TRANSFECTION; TRANSGENES; ULTRASONICS;

EID: 81255203782     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.08.020     Document Type: Article

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