Baicalein, isolated from Scutellaria baicalensis, protects against endothelin-1-induced pulmonary artery smooth muscle cell proliferation via inhibition of TRPC1 channel expression

Journal of Ethnopharmacology

Volumn 138, Issue 2, 2011, Pages 373-381

  Lin, Yi Ling ^a   Lin, Rong Jyh ^a   Shen, Kuo Pyng ^b   Dai, Zen Kong ^c   Chen, Ing Jun ^a   Wu, Jiunn Ren ^c   Wu, Bin Nan ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b MEIHO UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Baicalein; Calcium channel; Cell cycle; ET 1; Pulmonary arterial hypertension; TRPC1 channel

Indexed keywords

BAICALEIN; ENDOTHELIN 1; FURA 2 ACETOXYMETHYL ESTER; PROTEIN KINASE C ALPHA; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL CYCLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; DRUG EFFECT; DRUG MECHANISM; FEMALE; FLOW CYTOMETRY; NONHUMAN; PROTEIN EXPRESSION; PULMONARY ARTERY; RAT; SCUTELLARIA BAICALENSIS; SMOOTH MUSCLE FIBER; UPREGULATION;

ANIMALS; CALCIUM; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIN-1; FEMALE; FLAVANONES; FLOW CYTOMETRY; MUSCLE, SMOOTH, VASCULAR; PROTEIN KINASE C-ALPHA; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; SCUTELLARIA BAICALENSIS; TRPC CATION CHANNELS;

RATTUS; SCUTELLARIA BAICALENSIS;

EID: 81255171399     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.09.014     Document Type: Article

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