Effectiveness of Vernonia scorpioides ethanolic extract against skin inflammatory processes

Journal of Ethnopharmacology

Volumn 138, Issue 2, 2011, Pages 390-397

  Rauh, Laryssa K ^a   Horinouchi, Cíntia D S ^a   Loddi, Alliete M V ^a   Pietrovski, Evelise F ^a   Neris, Rosalina ^b   Souza Fonseca Guimarães, Fernando ^a   Buchi, Dorly F ^a   Biavatti, Maique W ^c   Otuki, Michel F ^d   Cabrini, Daniela A ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b UNIVERSIDADE DO VALE DO ITAJAÍ   (Brazil)

^c FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^d STATE UNIVERSITY OF PONTA GROSSA   (Brazil)

Author keywords

Anti inflammatory; Asteraceae; Ear oedema; Skin disorders; Vernonia scorpioides

Indexed keywords

ANTIINFLAMMATORY AGENT; ARACHIDONIC ACID; CROTON OIL; MYELOPEROXIDASE; N ACETYL BETA GLUCOSAMINIDASE; OXAZOLONE; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; UNCLASSIFIED DRUG; VERNONIA SCORPIOIDES EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFECT; EAR DISEASE; ENZYME ACTIVITY; HISTOLOGY; HYPERSENSITIVITY REACTION; LEUKOCYTE; MALE; MOUSE; NONHUMAN; SENSITIZATION; SKIN INFLAMMATION; VERNONIA; VERNONIA SCORPIOIDES;

ANIMALS; ARACHIDONIC ACID; DERMATITIS; ETHANOL; FLOW CYTOMETRY; HYPERSENSITIVITY, DELAYED; MALE; MICE; PLANT EXTRACTS; TETRADECANOYLPHORBOL ACETATE; VERONICA;

ANIMALIA; ASTERACEAE; VERNONIA;

EID: 81255171255     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.09.012     Document Type: Article

References (32)

1. M.K. Bedi, and P.D. Shenefelt Herbal therapy in dermatology Archives of Dermatology 138 2002 232 242 (Pubitemid 34160399)
2. J.D. Bos The skin as an organ of immunity Clinical and Experimental Immunology 107 1997 3 5
3. P.P. Bradley, D.A. Priebat, R.D. Christensen, and G. Rothstein Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker Journal of Investigative Dermatology 78 1982 206 209 (Pubitemid 12171880)
4. H. Buskuhl, R.A. Freitas, F.D. Monache, A. Barison, F.R. Campos, Y.E. Corilo, M.N. Eberlind, and M.B. Biavatti A new polyacetylene from Vernonia scorpioides (Lam.) Pers. (Asteraceae) and its in vitro antitumoral activity Journal of Brazilian Chemical Society 20 2009 1327 1333
5. H. Buskuhl, F.L. de Oliveira, L.Z. Blind, R.A. de Freitas, A. Barison, F.R. Campos, Y.E. Corilo, M.N. Eberlin, G.F. Caramori, and M.W. Biavatti Sesquiterpene lactones from Vernonia scorpioides and their in vitro cytotoxicity Phytochemistry 71 2010 1539 1544
6. J.B. Calixto, M.F. Otuki, and A.R.S. Santos Anti-inflammatory compounds of plant origin. Part I. Action on arachidonic acid pathway, nitric oxide and nuclear factor k-B (NF-kB) Planta Medica 69 2003 973 983 (Pubitemid 38064684)
7. C. Cuéllar, M.J. Perterguer, and M. Rodero Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders Fitoterapia 72 2001 221 229
8. L.M. De Young, J.B. Kheifets, S.J. Ballaron, and J.M. Young Edema and cell infiltration in the phorbol ester-treated mouse ear are temporally separate and can be differentially modulated by pharmacologic agents Agents and Actions 26 1989 335 341 (Pubitemid 19078128)
9. M.F.I. Freire, H.S. Abreu, L.C.H. Cruz, and R.B. Freire Inhibition of fungal growth by extracts of Vernonia scorpioides (Lam.) Pers. Microbiology 27 1996 1 6 (Pubitemid 26189450)
10. T. Fujii, K. Tanaka, S. Sakuma, Y. Ohkubo, and S. Mutoh Effects of FK506 (tacrolimus hydrate) on chronic oxazolone-induced dermatitis in rats European Journal of Pharmacology 456 2002 115 121 (Pubitemid 35351744)
11. G. Furstenberger, B.I. Csuk-Glanzer, F. Marks, and D. Keppler Phorbol ester-induced leukotriene biosynthesis and tumor promotion in mouse epidermis Carcinogenesis 15 1994 2823 2827
12. M. Gábor Mouse Ear Inflammation Models and their Pharmacological Applications 2000 Akadémiai Kiadó Budapeste
13. M. Gupta, U.K. Mazumder, L. Manikandan, P.K. Haldar, S. Bhattacharya, and C.C. Kandar Antibacterial activity of Vernonia cinerea Fitoterapia 74 2003 148 150 (Pubitemid 36287263)
14. B. Homey, M. Steinhoff, T. Ruzicka, and D.Y. Leung Cytokines and chemokines orchestrate atopic skin inflammation Journal of Allergy and Clinical Immunology 118 2006 178 189 (Pubitemid 43946487)
15. Y. Huang, Z.H. Ding, and J.K. Liu A new highly oxygenated flavone from Vernonia saligna Zeitschrift für Naturforschung C 58 2003 347 350 (Pubitemid 36814978)
16. E.B. Izevbigie, J.L. Bryant, and A. Walker A novel natural inhibitor of extracellular signal-regulated kinases and human breast cancer cell growth Experimental Biology and Medicine 229 2004 163 169 (Pubitemid 38146560)
17. J. Jakupovic, R.N. Baruah, T.V. Thi, F. Bohlmann, J.D. Msonthi, and G. Schmeda-Hirschmann New vernolepin derivatives from Vernonia glabra and glaucolides from Vernonia scorpioides Planta Medica 51 1985 378 380 (Pubitemid 16253768)
18. R.C. Johri, and C. Singh Medicinal uses of Vernonia species Journal of Medicinal and Aromatic Plant Sciences 19 1997 744 752
19. O. Kos, V. Castro, R. Murillo, L. Poveda, and I. Merfort Ent-kaurane glycosides and sesquiterpene lactones of the hirsutinolide type from Vernonia triflosculosa Phytochemistry 67 2006 62 69 (Pubitemid 41811249)
20. Y.H. Kuo, Y.J. Kuo, A.S. Yu, M.D. Wu, C.W. Ong, and L.M. Yang Kuo Two novel sesquiterpene lactones, cytotoxic vernolide-A and -B, from Vernonia cinerea Chemical and Pharmaceutical Bulletin 51 2003 425 426
21. S.N. Leite, G. Palhano, S. Almeida, and M.W. Biavatti Wound healing activity and systemic effects of Vernonia scorpioides extract in guinea pig Fitoterapia 73 2002 496 500 (Pubitemid 35266804)
22. U.K. Mazumder, M. Gupta, L. Manikandan, S. Bhattacharya, P.K. Haldar, and S. Roy Evaluation of anti-inflammatory activity of Vernonia cinerea less extract in rats Phytomedicine 10 2003 185 188 (Pubitemid 36433215)
23. C.S. Nergard, D. Diallo, T.E. Michaelsen, K.E. Malterud, H. Kiyohara, and T. Matsumoto Isolation, partial characterisation and immunomodulating activities of polysaccharides from Vernonia kotschyana Sch. Bip. Ex Walp. Journal of Ethnopharmacology 91 2004 141 152 (Pubitemid 38292046)
24. L. Pagno, L.Z. Blind, M.W. Biavatti, and M.R.O. Kreuguer Cytotoxic activity of dichloromethane fraction from Vernonia scorpioides (Lam.) Pers. (Asteraceae) against Ehrlich's tumor cells in mice Brazilian Journal of Medical and Biological Research 39 2006 1483 1491 (Pubitemid 46357864)
25. C. Robert, and T.S. Kupper Inflammatory skin diseases, T cells and immune surveillance The New England Journal of Medicine 341 1999 1817 1828
26. M.C. Recio, R.M. Giner, L. Uriburu, S. Máñez, M. Cerdá, and J.R. De La Fuente In vivo activity of pseudoguaianolide sesquiterpene lactones in acute and chronic inflammation Life Sciences 66 2000 2509 2518 (Pubitemid 30327466)
27. T. Sanchez, and J.J. Moreno Role of leukocyte influx in tissue prostaglandin H synthase-2 overexpression induced by phorbol ester and arachidonic acid in skin Biochemical Pharmacology 58 1999 877 879 (Pubitemid 29329539)
28. P.L. Stanley, S. Steiner, M. Havens, and K.M. Tramposh Mouse skin inflammation induced by multiple topical applications of 12-O- tetradecanoylphorbol-13-acetate Skin Pharmacology 4 1991 262 271
29. A.T. Tchinda, P. Tane, J.F. Ayafor, and J.D. Connolly Stigmastane derivatives and isovaleryl sucrose esters from Vernonia guineensis (Asteraceae) Phytochemistry 63 2003 841 846 (Pubitemid 36903598)
30. D.A.R. Valério, T.M. Cunha, N.S. Arakawa, H.P. Lemoa, F.B. Costa, and C.A. Parada Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism European Journal of Pharmacology 562 2003 155 163
31. J.M. Young, D.A. Spires, C.J. Bedord, B. Wagner, S.J. Ballaron, and L.M. De Young The mouse ear inflammatory response to topical arachidonic acid Journal of Investigative Dermatology 82 1984 367 371 (Pubitemid 14131463)
32. J.M. Young, B.M. Wagner, and D.A. Spires Tachyphylaxis in 12-tetradecanoylphorbol acetate- and arachidonic acid ear oedema Journal of Investigative Dermatology 80 1983 48 52 (Pubitemid 13171014)