Thrombin induces inducible nitric oxide synthase expression via the MAPK, MSK1, and NF-κB signaling pathways in alveolar macrophages

European Journal of Pharmacology

Volumn 672, Issue 1-3, 2011, Pages 180-187

  Lin, Chen Chun ^a   Shih, Chung Huang ^b,c   Yang, You Lan ^b   Bien, Mauo Ying ^b,c   Lin, Chien Huang ^b,d,e   Yu, Ming Chih ^d   Sureshbabu, Munisamy ^b   Chen, Bing Chang ^b  

^a SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Alveolar macrophage; iNOS (inducible nitric oxide synthase); MAPK (mitogen activated protein kinase); MSK1 (mitogen stress activated kinase 1); NF B (nuclear factor B); Thrombin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN STRESS ACTIVATED PROTEIN KINASE 1; PROTEIN SERINE THREONINE KINASE; PYRROLIDINE DITHIOCARBAMATE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; THROMBIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; LUNG ALVEOLUS MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TIME;

ANIMALS; CATTLE; CELL LINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MACROPHAGES, ALVEOLAR; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; RATS; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; SERINE; THROMBIN; TRANSCRIPTION FACTOR RELA;

EID: 81255135743     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.10.005     Document Type: Article

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