Signs of cross-seeding: Aortic medin amyloid as a trigger for protein AA deposition

Amyloid

Volumn 18, Issue 4, 2011, Pages 229-234

  Larsson, Annika ^a   Malmström, Susanna ^a,b   Westermark, Per ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b AMYLGEN   (France)

Author keywords

Aamyloid; Aorta; Cross seeding; Heterologous fibrils; Medamyloid; Medin; Seed

Indexed keywords

AMYLOID A PROTEIN; LACTADHERIN; PROTEIN PRECURSOR;

ADULT; AGED; AMYLOIDOSIS; AORTA WALL; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; IMMUNOFLUORESCENCE; IN VITRO STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN SYNTHESIS; THORACIC AORTA; TISSUE DISTRIBUTION;

AGED; AGED, 80 AND OVER; AMYLOID; AMYLOIDOSIS; ANTIGENS, SURFACE; AORTA, THORACIC; ARTHRITIS, PSORIATIC; ARTHRITIS, RHEUMATOID; FEMALE; HUMANS; MALE; MIDDLE AGED; MILK PROTEINS; PROTEIN MULTIMERIZATION; SERUM AMYLOID A PROTEIN;

EID: 81255124248     PISSN: 13506129     EISSN: 17442818     Source Type: Journal    
DOI: 10.3109/13506129.2011.630761     Document Type: Article

References (37)

1. Merlini G, Bellotti V. Molecular mechanisms of amyloidosis. N Engl J Med 2003;349:583-596. (Pubitemid 36951371)
2. Westermark P. Aspects on human amyloid forms and their fibril polypeptides. FEBS J 2005;272:5942-5949. (Pubitemid 41713686)
3. Ancsin JB, Kisilevsky R. The heparin/heparan sulfate-binding site on apo-serum amyloid A. Implications for the therapeutic intervention of amyloidosis. J Biol Chem 1999;274:7172-7181.
4. Relini A, Canale C, De Stefano S, Rolandi R, Giorgetti S, Stoppini M, Rossi A, et al. Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis. J Biol Chem 2006;281:16521-16529.
5. Ren R, Hong Z, Gong H, Laporte K, Skinner M, Seldin DC, Costello CE, et al. Role of glycosaminoglycan sulfation in the formation of immunoglobulin light chain amyloid oligomers and fibrils. J Biol Chem 2010;285:37672-37682.
6. Noborn F, O'Callaghan P, Hermansson E, Zhang X, Ancsin JB, Damas AM, Dacklin I, et al. Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein. Proc Natl Acad Sci USA 2011;108:5584-5589.
7. Lai Z, Colón W, Kelly JW. The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can selfassemble into amyloid. Biochemistry 1996;35:6470-6482. (Pubitemid 26164080)
8. Westermark GT, Sletten K, Westermark P. Massive vascular AA-amyloidosis: a histologically and biochemically distinctive subtype of reactive systemic amyloidosis. Scand J Immunol 1989;30:605-613. (Pubitemid 19280818)
9. Abraham RS, Geyer SM, Price-Troska TL, Allmer C, Kyle RA, Gertz MA, Fonseca R. Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain-associated amyloidosis (AL). Blood 2003;101:3801-3808. (Pubitemid 36857849)
10. Enqvist S, Sletten K, Stevens FJ, Hellman U, Westermark P. Germ line origin and somatic mutations determine the target tissues in systemic AL-amyloidosis. PLoS ONE 2007;2:e981.
11. Jarrett JT, Lansbury PT Jr. Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie? Cell 1993;73:1055-1058. (Pubitemid 23180480)
12. Rochet JC, Lansbury PT Jr. Amyloid fibrillogenesis: themes and variations. Curr Opin Struct Biol 2000;10:60-68. (Pubitemid 30099328)
13. O'Nuallain B, Williams AD, Westermark P, Wetzel R. Seeding specificity in amyloid growth induced by heterologous fibrils. J Biol Chem 2004;279:17490-17499. (Pubitemid 38560512)
14. Morales R, Estrada LD, Diaz-Espinoza R, Morales-Scheihing D, Jara MC, Castilla J, Soto C. Molecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseases. J Neurosci 2010;30:4528-4535.
15. Mucchiano G, Cornwell GG 3rd, Westermark P. Senile aortic amyloid. Evidence for two distinct forms of localized deposits. Am J Pathol 1992;140:871-877.
16. Häggqvist B, Näslund J, Sletten K, Westermark GT, Mucchiano G, Tjernberg LO, Nordstedt C, et al. Medin: an integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid. Proc Natl Acad Sci USA 1999;96:8669-8674. (Pubitemid 29354849)
17. Peng S, Glennert J, Westermark P. Medin-amyloid: a recently characterized age-associated arterial amyloid form affects mainly arteries in the upper part of the body. Amyloid 2005;12:96-102. (Pubitemid 40978717)
18. Larsson A, Peng S, Persson H, Rosenbloom J, Abrams WR, Wassberg E, Thelin S, et al. Lactadherin binds to elastin-a starting point for medin amyloid formation? Amyloid 2006;13:78-85. (Pubitemid 44266873)
19. Peng S, Larsson A, Wassberg E, Gerwins P, Thelin S, Fu X, Westermark P. Role of aggregated medin in the pathogenesis of thoracic aortic aneurysm and dissection. Lab Invest 2007;87:1195-1205. (Pubitemid 350126704)
20. Röcken C, Shakespeare A. Pathology, diagnosis and pathogenesis of AA amyloidosis. Virchows Arch 2002;440:111-122. (Pubitemid 34169846)
21. Westermark GT, Westermark P. Prion-like aggregates: infectious agents in human disease. Trends Mol Med 2010;16:501-507.
22. Gustavsson A, Engström U, Westermark P. Mechanisms of transthyretin amyloidogenesis. Antigenic mapping of transthyretin purified from plasma and amyloid fibrils and within in situ tissue localizations. Am J Pathol 1994;144:1301-1311. (Pubitemid 24172092)
23. Bergström J, Gustavsson A, Hellman U, Sletten K, Murphy CL, Weiss DT, Solomon A, et al. Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology. J Pathol 2005;206:224-232. (Pubitemid 40754027)
24. Peng S, Westermark GT, Näslund J, Häggqvist B, Glennert J, Westermark P. Medin and medin-amyloid in ageing inflamed and non-inflamed temporal arteries. J Pathol 2002;196:91-96.
25. Booth DR, Booth SE, Gillmore JD, Hawkins PN, Pepys MB. SAA1 alleles as risk factors in reactive systemic AA amyloidosis. Amyloid 1998;5:262-265. (Pubitemid 128690765)
26. Westermark GT, Sletten K, Grubb A, Westermark P. AA-amyloidosis. Tissue component-specific association of various protein AA subspecies and evidence of a fourth SAA gene product. Am J Pathol 1990;137: 377-383. (Pubitemid 20232998)
27. Li JP, Galvis ML, Gong F, Zhang X, Zcharia E, Metzger S, Vlodavsky I, et al. In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosis. Proc Natl Acad Sci USA 2005;102:6473-6477. (Pubitemid 40617467)
28. Larsson A, Söderberg L, Westermark GT, Sletten K, Engström U, Tjernberg LO, Näslund J, Westermark P. Unwinding fibril formation of medin, the peptide of the most common form of human amyloid. Biochem Biophys Res Commun 2007;361:822-828. (Pubitemid 47259013)
29. Olofsson A, Borowik T, Gröbner G, Sauer-Eriksson AE. Negatively charged phospholipid membranes induce amyloid formation of medin via an alpha-helical intermediate. J Mol Biol 2007;374:186-194. (Pubitemid 47600226)
30. Nerelius C, Gustafsson M, Nordling K, Larsson A, Johansson J. Antiamyloid activity of the C-terminal domain of proSP-C against amyloid beta-peptide and medin. Biochemistry 2009;48:3778-3786.
31. Westermark GT, Westermark P. Localized amyloids important in diseases outside the brain-lessons from the islets of Langerhans and the thoracic aorta. FEBS J 2011;278:3918-3929.
32. Petkova AT, Leapman RD, Guo Z, Yau WM, Mattson MP, Tycko R. Self-propagating, molecular-level polymorphism in Alzheimer's betaamyloid fibrils. Science 2005;307:262-265. (Pubitemid 40116242)
33. Lundmark K, Westermark GT, Nyström S, Murphy CL, Solomon A, Westermark P. Transmissibility of systemic amyloidosis by a prionlike mechanism. Proc Natl Acad Sci USA 2002;99:6979-6984. (Pubitemid 34526243)
34. Lundmark K, Westermark GT, Olsén A, Westermark P. Protein fibrils in nature can enhance amyloid protein A amyloidosis in mice: Cross-seeding as a disease mechanism. Proc Natl Acad Sci USA 2005;102:6098-6102. (Pubitemid 40594261)
35. Solomon A, Richey T, Murphy CL, Weiss DT, Wall JS, Westermark GT, Westermark P. Amyloidogenic potential of foie gras. Proc Natl Acad Sci USA 2007;104:10998-11001. (Pubitemid 47175215)
36. Kurosinski P, Guggisberg M, Götz J. Alzheimer's and Parkinson's disease-overlapping or synergistic pathologies? Trends Mol Med 2002;8:3-5. (Pubitemid 34044668)
37. Masliah E, Rockenstein E, Veinbergs I, Sagara Y, Mallory M, Hashimoto M, Mucke L. Beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease. Proc Natl Acad Sci USA 2001;98:12245-12250. (Pubitemid 32959858)