Mutation of Semaphorin-6A disrupts limbic and cortical connectivity and models neurodevelopmental psychopathology

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Rünker, Annette E ^a,c   O'Tuathaigh, Colm ^b   Dunleavy, Mark ^b   Morris, Derek W ^a   Little, Graham E ^a   Corvin, Aiden P ^a   Gill, Michael ^a   Henshall, David C ^b   Waddington, John L ^b   Mitchell, Kevin J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^c CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; DIZOCILPINE; HALOPERIDOL; SEMAPHORIN; SEMAPHORIN 6A; UNCLASSIFIED DRUG; SEMA6A PROTEIN, MOUSE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; BRAIN CORTEX; BRAIN FUNCTION; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; FEMALE; GENE; GENE INTERACTION; GENE MUTATION; HYPERACTIVITY; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NONHUMAN; PHENOTYPE; PSYCHOSIS; RECOGNITION; SCHIZOPHRENIA; SEMA6A GENE; SOCIAL INTERACTION; WORKING MEMORY; ANIMAL; ANXIETY; C57BL MOUSE; DISEASE MODEL; GAIT; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; LIMBIC SYSTEM; LOCOMOTION; MEMORY; MENTAL DISEASE; MOUSE MUTANT; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PREFRONTAL CORTEX; PSYCHOLOGICAL ASPECT;

MUS;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; FEMALE; GAIT; HUMANS; LIMBIC SYSTEM; LOCOMOTION; MALE; MEMORY; MENTAL DISORDERS; MICE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; MUTATION; NERVE NET; PHENOTYPE; PREFRONTAL CORTEX; SEMAPHORINS;

EID: 81255123172     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026488     Document Type: Article

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