Linkage of schizophrenia with chromosome 1q32 in Korean multiplex families'

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 144, Issue 3, 2007, Pages 279-284

  Yong, Lee Jang ^a   Jong, Won Kim ^a   Lee, Yu Sang ^b   Dong, Yeon Park ^a   Cho, Eun Young ^a   Hyun, Ok Jeun ^a   Lee, Dongsoo ^a   Kyung, Sue Hong ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Yongin Mental Hospital   (South Korea)

Author keywords

Chromosome 1; Family; Genetic study; Linkage analysis; Schizophrenia

Indexed keywords

ARTICLE; CHROMOSOME 1Q; CHROMOSOME MAP; GENE LOCATION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC EPIDEMIOLOGY; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; KOREA; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MICROSATELLITE MARKER; NONPARAMETRIC TEST; PRIORITY JOURNAL; SCHIZOPHRENIA;

CHROMOSOMES, HUMAN, PAIR 1; FAMILY; GENOTYPE; HUMANS; KOREA; LINKAGE (GENETICS); LOD SCORE; MICROSATELLITE REPEATS; SCHIZOPHRENIA;

EID: 34247376864     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30389     Document Type: Article

References (22)

1. Blackwood DH, Fordyce A, Walker MT, St Clair DM, Porteous DJ, Muir WJ. 2001. Schizophrenia and affective disorders - Cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: Clinical and P300 findings in a family. Am J Hum Genet 69:428-433.
2. Brzustowicz LM, Hodgkinson KA, Chow EW, Honer WG, Bassett AS. 2000. Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22. Science 288:678-682.
3. Cannon TD, Kaprio J, Lonnqvist J, Huttunen M, Koskenvuo M. 1998. The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study. Arch Gen Psychiatry 55:67-74.
4. Cardno AG, Gottesman XX II. 2000. Twin studies of schizophrenia: From bow-and-arrow concordances to star wars Mx and functional genomics. Am J Med Genet 97:12-17.
5. Chiavetto LB, Boin F, Zanardini R, Popoli M, Michelato A, Bignotti S, Tura GB, Gennarelli M. 2002. Association between promoter polymorphic haplotypes of interleukin-10 gene and schizophrenia. Biol Psychiatry 51:480-484.
6. DeLisi LE, Shaw SH, Crow TJ, Shields G, Smith AB, Larach VW, Wellman N, Loftus J, Nanthakumar B, Razi K, Stewart J, Comazzi M, Vita A, Heffner T, Sherrington R. 2002. A genome-wide scan for linkage to chromosomal regions in 382 sibling pairs with schizophrenia or schizoaffective disorder. Am J Psychiatry 159:803-812.
7. Ekelund J, Lichtermann D, Hovatta I, Ellonen P, Suvisaari J, Terwilliger JD, Juvonen H, Varilo T, Arajarvi R, Kokko-Sahin ML, Lonnqvist J, Peltonen L. 2000. Genome-wide scan for schizophrenia in the Finnish population: Evidence for a locus on chromosome 7q22. Hum Mol Genet 9:1049-1057.
8. Ekelund J, Hovatta I, Parker A, Paunio T, Varilo T, Martin R, Suhonen J, Ellonen P, Chan G, Sinsheimer JS, Sobel E, Juvonen H, Arajarvi R, Partonen T, Suvisaari J, Lonnqvist J, Meyer J, Peltonen L. 2001. Chromosome 1 loci in Finnish schizophrenia families. Hum Mol Genet 10:1611-1617.
9. Ekelund J, Hennah W, Hiekkalinna T, Parker A, Meyer J, Lonnqvist J, Peltonen L. 2004. Replication of 1q42 linkage in Finnish schizophrenia pedigrees. Mol Psychiatry 9:1037-1041.
10. Faraone SV, Matise T, Svrakic D, Pepple J, Malaspina D, Suarez B, Hampe C, Zambuto CT, Schmitt K, Meyer J, Markel P, Lee H, Harkavy Friedman J, Kaufmann C, Cloninger CR, Tsuang MT. 1998. Genome scan of European-American schizophrenia pedigrees: Results of the NIMH Genetics Initiative and Millennium Consortium. Am J Med Genet 81:290-295.
11. Gurling HM, Kalsi G, Brynjolfson J, Sigmundsson T, Sherrington R, Mankoo BS, Read T, Murphy P, Blaveri E, McQuillin A, Petursson H, Curtis D. 2001. Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23. Am J Hum Genet 68:661-673.
12. Hovatta I, Varilo T, Suvisaari J, Terwilliger JD, Ollikainen V, Arajarvi R, Juvonen H, Kokko-Sahin ML, Vaisanen L, Mannila H, Lonnqvist J, Peltonen L. 1999. A genomewide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci. Am J Hum Genet 65:1114-1124.
13. Hwu HG, Liu CM, Fann CS, Ou-Yang WC, Lee SF. 2003. Linkage of schizophrenia with chromosome 1q loci in Taiwanese families. Mol Psychiatry 8:445-452.
14. Joo EJ, Joo YH, Hong JP, Hwang S, Maeng SJ, Han JH, Yang BH, Lee YS, Kim YS. 2004. Korean version of the diagnostic interview for genetic studies: Validity and reliability. Compr Psychiatry 45(3):225-229.
15. Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES. 1996. Parametric and nonparametric linkage analysis: A unified multipoint approach. Am J Hum Genet 58:1347-1363.
16. Levinson DF, Holmans PA, Laurent C, Riley B, Pulver AE, Gejman PV, Schwab SG, Williams NM, Owen MJ, Wildenauer DB, Sanders AR, Nestadt G, Mowry BJ, Wormley B, Bauche S, Soubigou S, Ribble R, Nertney DA, Liang KY, Martinolich L, Maier W, Norton N, Williams H, Albus M, Carpenter EB, DeMarchi N, Ewen-White KR, Walsh D, Jay M, Deleuze JF, O'Neill FA, Papadimitriou G, Weilbaecher A, Lerer B, O'Donovan MC, Dikeos D, Silverman JM, Kendler KS, Mallet J, Crowe RR, Walters M. 2002. No major schizophrenia locus detected on chromosome 1q in a large multicenter sample. Science 296:739-741.
17. Maziade M, Fournier A, Phaneuf D, Cliche D, Fournier JP, Roy MA, Merette C. 2002. Chromosome 1q12-q22 linkage results in eastern Quebec families affected by schizophrenia. Am J Med Genet 114:51-55.
18. Millar JK, Wilson-Annan JC, Anderson S, Christie S, Taylor MS, Semple CA, Devon RS, Clair DM, Muir WJ, Blackwood DH, Porteous DJ. 2000. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet 9:1415-1423.
19. Paunio T, Ekelund J, Varilo T, Parker A, Hovatta I, Turunen JA, Rinard K, Foti A, Terwilliger JD, Juvonen H, Suvisaari J, Arajarvi R, Suokas J, Partonen T, Lonnqvist J, Meyer J, Peltonen L. 2001. Genome-wide scan in a nationwide study sample of schizophrenia families in Finland reveals susceptibility loci on chromosomes 2q and 5q. Hum Mol Genet 10:3037-3048.
20. Shaw SH, Kelly M, Smith AB, Shields G, Hopkins PJ, Loftus J, Laval SH, Vita A, De Hert M, Cardon LR, Crow TJ, Sherrington R, DeLisi LE. 1998. A genome-wide search for schizophrenia susceptibility genes. Am J Med Genet 81:364-376.
21. Stone WS, Faraone SV, Su J, Tarbox SI, Van Eerdewegh P, Tsuang MT. 2004. Evidence for linkage between regulatory enzymes in glycolysis and schizophrenia in a multiplex sample. Am J Med Genet Part B Neuropsychiatr Genet 127B:5-10.
22. Yu L, Yang MS, Zhao J, Shi YY, Zhao XZ, Yang JD, Liu ZJ, Gu NF, Feng GY, He L. 2004. An association between polymorphisms of the interleukin-10 gene promoter and schizophrenia in the Chinese population. Schizophr Res 71:179-183.